2. Metabolic Enzyme/Protease Apoptosis
  3. HMG-CoA Reductase (HMGCR) Apoptosis
  4. Fluvastatin sodium monohydrate

Fluvastatin sodium monohydrate  (Synonyms: XU 62-320 monohydrate)

Cat. No.: HY-14664D
Handling Instructions Technical Support

Fluvastatin (XU 62-320) sodium monohydrate is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8 nM. Fluvastatin (sodium monohydrate) protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

For research use only. We do not sell to patients.

CAS No. : 201541-53-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Fluvastatin sodium monohydrate:

Other Forms of Fluvastatin sodium monohydrate:

Fluvastatin sodium monohydrate Related Antibodies

Top Publications Citing Use of Products

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592.  [Abstract]

    HFD C57BL/6 mice intravenously injected with 1 × 106 Cd36NC or Cd36KO C1498 cells were treated with or without reagents (fluvastatin, 40 mg/kg, 5 times/week, intragastric).

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592.  [Abstract]

    Tumors from 3 recipients were dissected for immunohistochemistry staining with anti-human CD3 antibody treated with fluvastatin (40 mg/kg, 5 times/week, i.g.) for 2 weeks.

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592.  [Abstract]

    NOG mice intravenously implanted with 5 × 106 BMMCs from patients with AML were treated with or without fluvastatin (40 mg/kg, 5 times/week, i.g.) for 2 weeks starting 7 days after implantation. 3 days after the last treatment, percentages of human AML cells and human T cells in BM were tested.

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: PLoS Biol.2024 May 28;22(5):e3002621.  [Abstract]

    The 7-DHC, cholesterol levels, and qRT-PCR analyses of metastatic-related genes of A549 cells cultured in LPDS medium treated with 5 μg/mL cholesterol with or without 10 μM fluvastatin for 24 h.

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: PLoS Biol.2024 May 28;22(5):e3002621.  [Abstract]

    Cell viability of foxa3hi PDO treated with 10 μM Magnolol, 10 μM Fluvastatin, or 10 μM Cisplatin by ATP assay.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Fluvastatin (XU 62-320) sodium monohydrate is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8 nM. Fluvastatin (sodium monohydrate) protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2].

    Molecular Weight

    451.46

    Formula

    C24H27FNNaO5
    CAS No.
    SMILES

    O=C(O[Na])C[C@@H](O)C[C@@H](O)/C=C/C1=C(C2=CC=C(C=C2)F)C3=CC=CC=C3N1C(C)C.O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    Fluvastatin sodium monohydrate Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Fluvastatin sodium201541-53-9XU 62-320HMG-CoA Reductase (HMGCR)Apoptosishuman coronary artery smooth muscle cellsantioxidantHepG2SMMC-7721MHCC-97HInhibitorinhibitorinhibit

    Your Recently Viewed Products:

    Inquiry Online

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Requested Quantity *

    Applicant Name *

    		 

    Salutation

    Email Address *

    		 

    Phone Number *

    Department

    		 

    Organization Name *

    City

    State

    Country or Region *

    		      

    Remarks

    Bulk Inquiry

    Inquiry Information

    Product Name:
    Fluvastatin sodium monohydrate
    Cat. No.:
    HY-14664D
    Quantity:
    MCE Japan Authorized Agent:

    Customer Review

    Thank You for Your Feedback!

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Lot #

    Applicant Name *

    		 

    Email Address *

    Phone Number

    		 

    Department *

    Organization Name *

    		 

    Country or Region *

    Remarks

    SAFETY DATA SHEET (SDS)

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.