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Fluvastatin sodium monohydrate

(Synonyms: XU 62-320 monohydrate)
20 Cited Publications
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Based on 20 publication(s) in Google Scholar

Fluvastatin (XU 62-320) sodium monohydrate is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8 nM. Fluvastatin (sodium monohydrate) protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

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  • CAS No.: 201541-53-9
  • Formula: C24H27FNNaO5
  • Molecular Weight:451.46
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Fluvastatin sodium monohydrate Chemical Structure
    Fluvastatin sodium monohydrate Chemical Structure
  • Experimental Validation Results for Fluvastatin sodium monohydrate
  • Experimental Validation Results for Fluvastatin sodium monohydrate
  • Experimental Validation Results for Fluvastatin sodium monohydrate
  • Experimental Validation Results for Fluvastatin sodium monohydrate
  • Experimental Validation Results for Fluvastatin sodium monohydrate
CAS No.: 201541-53-9
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  • Fluvastatin sodium monohydrate Chemical Structure
    Fluvastatin sodium monohydrate Chemical Structure
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    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592. [Abstract]

    Customer Validation
     HFD C57BL/6 mice intravenously injected with 1 × 106 Cd36NC or Cd36KO C1498 cells were treated with or without reagents (fluvastatin, 40 mg/kg, 5 times/week, intragastric).

  • 1/16

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592. [Abstract]

    Customer Validation
     Tumors from 3 recipients were dissected for immunohistochemistry staining with anti-human CD3 antibody treated with fluvastatin (40 mg/kg, 5 times/week, i.g.) for 2 weeks.

  • 1/16

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 May 29:101592. [Abstract]

    Customer Validation
     NOG mice intravenously implanted with 5 × 106 BMMCs from patients with AML were treated with or without fluvastatin (40 mg/kg, 5 times/week, i.g.) for 2 weeks starting 7 days after implantation. 3 days after the last treatment, percentages of human AML cells and human T cells in BM were tested.

  • 1/16

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: PLoS Biol.2024 May 28;22(5):e3002621. [Abstract]

    Customer Validation
     The 7-DHC, cholesterol levels, and qRT-PCR analyses of metastatic-related genes of A549 cells cultured in LPDS medium treated with 5 μg/mL cholesterol with or without 10 μM fluvastatin for 24 h.

  • 1/16

    Fluvastatin sodium monohydrate purchased from MedChemExpress. Usage Cited in: PLoS Biol.2024 May 28;22(5):e3002621. [Abstract]

    Customer Validation
     Cell viability of foxa3hi PDO treated with 10 μM Magnolol, 10 μM Fluvastatin, or 10 μM Cisplatin by ATP assay.

  • Fluvastatin sodium monohydrate