1. Metabolic Enzyme/Protease
  2. HMG-CoA Reductase (HMGCR)
  3. (3S,5R)-Fluvastatin sodium

(3S,5R)-Fluvastatin sodium  (Synonyms: (3S,5R)-XU 62-320)

Cat. No.: HY-14664C Purity: 98.16% ee.: 98.59%
COA Handling Instructions

(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

For research use only. We do not sell to patients.

(3S,5R)-Fluvastatin sodium Chemical Structure

(3S,5R)-Fluvastatin sodium Chemical Structure

CAS No. : 94061-81-1

Size Price Stock Quantity
5 mg USD 510 In-stock
10 mg USD 816 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of (3S,5R)-Fluvastatin sodium:

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Description

(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].

Molecular Weight

433.45

Formula

C24H25FNNaO4

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC1=CC=C(C2=C(/C=C/[C@H](O)C[C@H](O)CC(O[Na])=O)N(C(C)C)C3=C2C=CC=C3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (115.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3071 mL 11.5354 mL 23.0707 mL
5 mM 0.4614 mL 2.3071 mL 4.6141 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3071 mL 11.5354 mL 23.0707 mL 57.6768 mL
5 mM 0.4614 mL 2.3071 mL 4.6141 mL 11.5354 mL
10 mM 0.2307 mL 1.1535 mL 2.3071 mL 5.7677 mL
15 mM 0.1538 mL 0.7690 mL 1.5380 mL 3.8451 mL
20 mM 0.1154 mL 0.5768 mL 1.1535 mL 2.8838 mL
25 mM 0.0923 mL 0.4614 mL 0.9228 mL 2.3071 mL
30 mM 0.0769 mL 0.3845 mL 0.7690 mL 1.9226 mL
40 mM 0.0577 mL 0.2884 mL 0.5768 mL 1.4419 mL
50 mM 0.0461 mL 0.2307 mL 0.4614 mL 1.1535 mL
60 mM 0.0385 mL 0.1923 mL 0.3845 mL 0.9613 mL
80 mM 0.0288 mL 0.1442 mL 0.2884 mL 0.7210 mL
100 mM 0.0231 mL 0.1154 mL 0.2307 mL 0.5768 mL
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(3S,5R)-Fluvastatin sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(3S,5R)-Fluvastatin sodium
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