1. Metabolic Enzyme/Protease
    Autophagy
  2. HMG-CoA Reductase (HMGCR)
    Autophagy
  3. (3R,5S)-Fluvastatin

(3R,5S)-Fluvastatin (Synonyms: (3R,5S)-XU 62-320 free acid)

Cat. No.: HY-14664B
Handling Instructions

(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

For research use only. We do not sell to patients.

(3R,5S)-Fluvastatin Chemical Structure

(3R,5S)-Fluvastatin Chemical Structure

CAS No. : 155229-75-7

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Description

(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].

Molecular Weight

411.47

Formula

C₂₄H₂₆FNO₄

CAS No.

155229-75-7

SMILES

O=C(O)C[[email protected]](O)C[[email protected]](O)/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(3R,5S)-Fluvastatin(3R,5S)-XU 62-320HMG-CoA Reductase (HMGCR)AutophagyHMG-CoAreductasevascularsmoothmuscleoxidativestressNrf2-dependentantioxidantpathwayInhibitorinhibitorinhibit

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