1. GPCR/G Protein
  2. Adenosine Receptor
  3. Derenofylline

Derenofylline (Synonyms: SLV 320)

Cat. No.: HY-14858
Handling Instructions

Derenofylline is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2Areceptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats.

For research use only. We do not sell to patients.

Derenofylline Chemical Structure

Derenofylline Chemical Structure

CAS No. : 251945-92-3

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Description

Derenofylline is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2Areceptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1].

IC50 & Target

Ki: 1 nM (adenosine A1 receptor)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

308.38

Formula

C₁₈H₂₀N₄O

CAS No.

251945-92-3

SMILES

O[[email protected]]1CC[[email protected]](NC2=C3C(NC=C3)=NC(C4=CC=CC=C4)=N2)CC1

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Derenofylline
Cat. No.:
HY-14858
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Derenofylline

Cat. No.: HY-14858