Search Result

Results for "

degradation+product

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADAMTS (1) Akt (1) Amino Acid Derivatives (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (12) Apoptosis (5) Aryl Hydrocarbon Receptor (1) Bacterial (9) Biochemical Assay Reagents (9) Complement System (1) Cuproptosis (3) CXCR (1) Cyclophilin (1) DNA/RNA Synthesis (1) Drug Derivative (17) Drug Intermediate (5) Drug Metabolite (55) Endogenous Metabolite (13) Environmental Pollutants (7) Estrogen Receptor/ERR (1) GLP Receptor (1) GnRH Receptor (2) HCV (2) Herbicide (6) Histamine Receptor (2) HIV (2) HIV Protease (1) HPPD (1) IFNAR (1) Insecticide (3) Interleukin Related (1) Isotope-Labeled Compounds (10) MDM-2/p53 (1) Neprilysin (1) Parasite (3) PDK-1 (1) PTEN (1) Reactive Oxygen Species (ROS) (4) Reference Standards (21) Reverse Transcriptase (2) TNF Receptor (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (6) Endocrinology (4) Infection (33) Inflammation/Immunology (14) Metabolic Disease (16) Neurological Disease (6)

By Targets:

ADAMTS (1)

Akt (1)

Amino Acid Derivatives (1)

Angiotensin-converting Enzyme (ACE) (1)

Antibiotic (12)

Apoptosis (5)

Aryl Hydrocarbon Receptor (1)

Bacterial (9)

Biochemical Assay Reagents (9)

Complement System (1)

Cuproptosis (3)

CXCR (1)

Cyclophilin (1)

DNA/RNA Synthesis (1)

Drug Derivative (17)

Drug Intermediate (5)

Drug Metabolite (55)

Endogenous Metabolite (13)

Environmental Pollutants (7)

Estrogen Receptor/ERR (1)

GLP Receptor (1)

GnRH Receptor (2)

HCV (2)

Herbicide (6)

Histamine Receptor (2)

HIV (2)

HIV Protease (1)

HPPD (1)

IFNAR (1)

Insecticide (3)

Interleukin Related (1)

Isotope-Labeled Compounds (10)

MDM-2/p53 (1)

Neprilysin (1)

Parasite (3)

PDK-1 (1)

PTEN (1)

Reactive Oxygen Species (ROS) (4)

Reference Standards (21)

Reverse Transcriptase (2)

TNF Receptor (1)

By Research Areas:

Cancer (20)

Cardiovascular Disease (6)

Endocrinology (4)

Infection (33)

Inflammation/Immunology (14)

Metabolic Disease (16)

Neurological Disease (6)

150

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7387

3-Oxocholic acid 3-Dehydrocholic acid	Endogenous Metabolite	Metabolic Disease
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-113063

3-Methyl-2-oxovaleric acid 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-B1027

4-Nonylphenol polyethoxylate Nonoxynol; Nonoxinol	Environmental Pollutants Biochemical Assay Reagents	Others
4-Nonylphenol polyethoxylate (Nonoxynol) is a non-ionic surfactant. 4-Nonylphenol polyethoxylate forms degradation products including 4-nonylphenol and short ethoxyl chain polyethoxylates. 4-Nonylphenol polyethoxylate generates degradation products that exhibit estrogenic activity, persist in aquatic environments, and bioaccumulate in the food chain .

HY-N7449

Neamine	Antibiotic Bacterial	Infection Cardiovascular Disease Neurological Disease Cancer
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-W724905

gamma-Glutamylisoleucine γ-Glu-Ile; H-γ-Glu-Ile-OH	Amino Acid Derivatives	Others
gamma-Glutamylisoleucine (γ-Glu-Ile; H-γ-Glu-Ile-OH) is a dipeptide composed of γ-glutamic acid and isoleucine, and it is also a degradation product of macromolecular proteins after proteolysis .

HY-W017386

3-Methyl-2-oxovaleric acid sodium 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-B1514

Allantoic acid 1 Publications Verification	Endogenous Metabolite	Others
Allantoic acid is a degradative product of uric acid and associated with purine metabolism .

HY-113412A

3-Methylhistamine dihydrochloride	Endogenous Metabolite	Inflammation/Immunology
3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice .

HY-129043

3-Formyl rifamycin	Drug Metabolite	Infection
3-Formyl rifamycin is an acid degradation product of the broad-spectrum antibiotic Rifampicin (HY-B0272). 3-Formyl rifamycin forms via acid hydrolysis of Rifampicin in an acidic environment .

HY-115349

Neamine tetrahydrochloride	Antibiotic Bacterial	Infection Neurological Disease Cancer
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .

HY-133597

4-Chlorocatechol	Drug Derivative	Others
4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase .

HY-129072

Isocyclosporin A	Complement System Cyclophilin Drug Metabolite	Cardiovascular Disease
Isocyclosporin A is a degradation product of the immunosuppressant Cyclosporin A .

HY-121652

Mefox	Drug Metabolite	Others
Mefox is a degradation product of folic acid (HY-16637) .

HY-W010593

Ethylenethiourea	Environmental Pollutants Drug Metabolite	Cancer
Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active .

HY-125947

4-Epioxytetracycline	Drug Metabolite	Others
4-Epioxytetracycline, the degradation product of Oxytetracycline (OTC), can be found in swine manure compost and wastewater .

HY-122207

Erythromycin A enol ether	Antibiotic	Infection
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .

HY-132995

DP-1	Drug Metabolite	Others
DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib. Ganetespib is a heat shock protein 90 (HSP90) inhibitor with anti-tumor activity .

HY-79602

p-Toluenesulfonamide	Biochemical Assay Reagents Drug Derivative Drug Intermediate	Others
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-125446

2-Hydroxymethyl olanzapine LY-290411; 2-OH-OLZ	Drug Metabolite	Others
2-Hydroxymethyl olanzapine is a metabolite and a degradation product of Olanzapine (HY-14541) ^[1][2].

HY-137252

22,23-Dihydroavermectin B1a aglycon Ivermectin Impurity G	Parasite	Infection
22,23-Dihydroavermectin B1a aglycon is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.

HY-17412B

4-Epiminocycline	Drug Metabolite	Others
4-Epiminocycline is a Minocycline (HY-17412A) degradation product. Minocycline (HY-17412A) is an antibiotic that has anti-inflammatory, anticancer, antibacterial, immunomodulatory and neuroprotective effects .

HY-138149

2-epi-Abamectin epi-Avermectin B1a	Drug Metabolite	Infection
2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.

HY-W717548

Safinamide acid	Drug Metabolite	Others
Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .

HY-W718316

5,6-Chrysenedione	Drug Metabolite	Others
5,6-Chrysenedione is the photochemical degradation product of 6-Aminochrysene (HY-108315) .

HY-137196

Anhydrochlortetracycline hydrochloride	Bacterial	Infection
Anhydrochlortetracycline hydrochloride is a degradation product of chlortetracycline (HY-B1327A). Anhydrochlortetracycline hydrochloride inhibits the growth of actinomycetes .

HY-P4724

(β-Asp28)-Exenatide	Drug Derivative	Metabolic Disease
(β-Asp28)-Exenatide is a potential degradation product of exenatide produced by the formation and cleavage of asparagine.

HY-100096

Emtricitabine S-oxide Emtricitabine sulfoxide; Emtricitabine Degradant-III	HIV Reverse Transcriptase	Infection
Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.

HY-13938

Iretol 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .

HY-P3675

LH-RH (4-10)	GnRH Receptor	Endocrinology
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .

HY-P3674

LH-RH (7-10)	GnRH Receptor	Endocrinology
LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes .

HY-B1855

cis-Heptachlor epoxide Epoxyheptachlor	Biochemical Assay Reagents	Others
(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.

HY-136381

N-Nitrosoglyphosate sodium N-Nitroso-N-(phosphonoMethyl)glycine sodium; Glyphosate-N-nitroso sodium	Drug Metabolite	Others
N-Nitrosoglyphosate sodium is the nitrosamine degradation product and synthetic impurity of glyphosate herbicide .

HY-111742

Bifenazate-diazene	Drug Metabolite	Others
Bifenazate-diazene is a major degradation product of Bifenazate. Bifenazate is a selective carbazate acaricide and an insecticide .

HY-W705140A

Monohydroxy melphalan hydrochloride Hydroxymelphalan hydrochloride	Drug Metabolite	Cancer
Monohydroxy melphalan hydrochloride (Hydroxymelphalan hydrochloride) is a degradation product of Melphalan (HY-17575), obtained through the hydrolysis of Melphalan in aqueous solutions (including cell culture media and human plasma) .

HY-B0300S

Penicillamine-d3 D-(-)-Penicillamine-d₃	Drug Metabolite Isotope-Labeled Compounds Cuproptosis	Inflammation/Immunology
Penicillamine-d₃ is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.

HY-N7449R

Neamine (Standard)	Antibiotic Reference Standards Bacterial	Infection Cardiovascular Disease Neurological Disease Cancer
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-N15681

β-Apo-10'-carotenal 10'-Apo-β-carotenal	Drug Metabolite	Others
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-112108D

Chitosan oligosaccharide (MW 2000) COS (MW 2000)	Biochemical Assay Reagents	Others
Chitosan oligosaccharide (MW 2000) (COS (MW 2000)) is a degradation product of chitosan. It is an oligosaccharide composed of 2-20 glucosamine groups linked by β-(1→4) glycosidic bonds .

HY-125947R

4-Epioxytetracycline (Standard)	Reference Standards Drug Metabolite	Others
4-Epioxytetracycline (Standard) is the analytical standard of 4-Epioxytetracycline. This product is intended for research and analytical applications. 4-Epioxytetracycline, the degradation product of Oxytetracycline (OTC), can be found in swine manure compost and wastewater .

HY-W174556

2-(3-Methylbenzyl)succinic acid 3-mBSA	Drug Derivative	Others
2-(3-Methylbenzyl)succinic acid (3-mBSA) is a degradation product of anaerobic toluene and ethylbenzene/xylene. 2-(3-Methylbenzyl)succinic acid can serve as a qualitative in situ indicator of toluene and ethylbenzene/xylene in contaminated groundwater .

HY-P2658

[Des-Tyr1]-Met-Enkephalin	Neprilysin	Others
[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins .

HY-W518478

Zolpyridine	Drug Metabolite	Others
Zolpyridine is a degradation product of Zolpidem tartrate .

HY-122035

Flambalactone	Bacterial	Infection
Flambalactone is a degradation product formed by methanolysis of the antibiotic flambamycin.

HY-135586

Raloxifene N-Oxide	Drug Metabolite	Metabolic Disease
Raloxifene N-Oxide is a Raloxifene oxidative degradation product .

HY-Z9082

Dihydroxy melphatalan	Drug Metabolite	Others
Dihydroxy melphalan is an inactive degradation product of Melphalan (HY-17575).

HY-119660

Surgumycin	Antibiotic Bacterial	Others
Surgumycin is a compound with antimicrobial activity, and its structure was determined by studying its degradation products.

HY-N12842

2-Deoxokanshone L	Drug Metabolite	Others
2-Deoxokanshone L is a degradation product of Nardosinone (HY-N0380) .

HY-W585893

Endrin ketone	Drug Metabolite	Cancer
Endrin ketone is an Endrin (HY-W585893) degradation product. Endrin is a carcinogen .

HY-W104125

Zopiclone impurity-1 RP 29307	Drug Metabolite	Others
Zopiclone impurity-1 (RP 29307) is an impurity and degradation product in the production process of zopiclone .

HY-136986

Desthiazolylmethyl ritonavir	HIV Protease	Infection
Desthiazolylmethyl ritonavir is a base-catalyzed degradation product of the HIV protease inhibitor Ritonavir (HY-90001).

Cat. No.	Product Name	Type

HY-W017386

3-Methyl-2-oxovaleric acid sodium 3 Publications Verification	Biochemical Assay Reagents
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-79602

p-Toluenesulfonamide	Biochemical Assay Reagents
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-B1855

cis-Heptachlor epoxide Epoxyheptachlor	Biochemical Assay Reagents
(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.

HY-112108D

Chitosan oligosaccharide (MW 2000) COS (MW 2000)	Biochemical Assay Reagents
Chitosan oligosaccharide (MW 2000) (COS (MW 2000)) is a degradation product of chitosan. It is an oligosaccharide composed of 2-20 glucosamine groups linked by β-(1→4) glycosidic bonds .

HY-79602R

p-Toluenesulfonamide (Standard)

Biochemical Assay Reagents

p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-B1855R

cis-Heptachlor epoxide (Standard)

Epoxyheptachlor (Standard)

Biochemical Assay Reagents

cis-Heptachlor epoxide (Standard) is the analytical standard of cis-Heptachlor epoxide. This product is intended for research and analytical applications. (±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.

Cat. No.	Product Name	Target	Research Area

HY-W724905

gamma-Glutamylisoleucine γ-Glu-Ile; H-γ-Glu-Ile-OH	Amino Acid Derivatives	Others
gamma-Glutamylisoleucine (γ-Glu-Ile; H-γ-Glu-Ile-OH) is a dipeptide composed of γ-glutamic acid and isoleucine, and it is also a degradation product of macromolecular proteins after proteolysis .

HY-P4846

Ac-Pro-Gly-Pro-OH 2 Publications Verification	CXCR Apoptosis IFNAR TNF Receptor Interleukin Related	Infection Inflammation/Immunology
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .

HY-106263B

Tyroserleutide hydrochloride	PTEN PDK-1 MDM-2/p53 Apoptosis Akt	Cancer
Tyroserleutide hydrochloride is a tripeptide isolated from the degradation products of porcine spleen with antitumor activity. Tyroserleutide hydrochloride can upregulate the expression of the tumor suppressor gene PTEN and inhibit the activity of AKT and PDK1. Tyroserleutide hydrochloride inhibits tumor cell proliferation and MDM2 phosphorylation by inhibiting the PI3K/AKT pathway, and also upregulates P21, P27, P53, and induces mitochondrial damage and cell apoptosis .

HY-P4724

(β-Asp28)-Exenatide	Drug Derivative	Metabolic Disease
(β-Asp28)-Exenatide is a potential degradation product of exenatide produced by the formation and cleavage of asparagine.

HY-P3675

LH-RH (4-10)	GnRH Receptor	Endocrinology
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .

HY-P3674

LH-RH (7-10)	GnRH Receptor	Endocrinology
LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes .

HY-P2658

[Des-Tyr1]-Met-Enkephalin	Neprilysin	Others
[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins .

HY-P4372

Hepcidin-22 (human)	Peptides	Others
Hepcidin-22 (human) is an inactive degradation product of hepcidin-25 that is present in the urine .

HY-106263A

Tyroserleutide TFA	Peptides	Cancer
Tyroserleutide TFA, isolated from the degradation products of porcine spleen , is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo .

HY-106263

Tyroserleutide	Peptides	Cancer
Tyroserleutide (YSL), isolated from the degradation products of porcine spleen , is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo .

HY-P4386

(Asp28)-Exenatide	GLP Receptor	Metabolic Disease
(Asp28)-Exenatide is a degradation product of exenatide (HY-13443). (Asp28)-Exenatide can be used as a GLP-1R agonist .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0300

Penicillamine 3 Publications Verification D-(-)-Penicillamine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Inflammation/Immunology Disease Research Fields Source Classification	Cuproptosis Drug Metabolite
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine increases free copper and increases oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-N7387

3-Oxocholic acid 3-Dehydrocholic acid	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-N7495

all-trans-Anhydro Retinol Anhydrovitamin A	Classification of Application Fields Terpenoids Metabolic Disease Diterpenoids Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

HY-113063

3-Methyl-2-oxovaleric acid 3 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-N7449

Neamine	Infection Cardiovascular Disease Classification of Application Fields Disease Research Fields	Antibiotic Bacterial
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-W012575

2,4-Dihydroxybenzoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
2,4-Dihydroxybenzoic acid is a degradation product of acid cherry anthocyanins during in vitro cell culture and an analogue of coenzyme Q precursor molecules. 2,4-Dihydroxybenzoic acid can improve the related symptoms of kidney diseases caused by ADCK4/Coq6 deficiency .

HY-B1514

Allantoic acid 1 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Allantoic acid is a degradative product of uric acid and associated with purine metabolism .

HY-113412A

3-Methylhistamine dihydrochloride	Alkaloids Classification of Application Fields Other Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice .

HY-113063R

3-Methyl-2-oxovaleric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
3-Methyl-2-oxovaleric acid (Standard) is the analytical standard of 3-Methyl-2-oxovaleric acid (HY-113063). This product is intended for research and analytical applications. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone.

HY-13938

Iretol 1 Publications Verification	Classification of Application Fields Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .

HY-N15681

β-Apo-10'-carotenal 10'-Apo-β-carotenal	Natural Products Microorganisms Source Classification	Drug Metabolite
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-N7454

Anhydroerythromycin A	Infection Structural Classification Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Bacterial
Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

HY-N12842

2-Deoxokanshone L	Natural Products Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae Source Classification	Drug Metabolite
2-Deoxokanshone L is a degradation product of Nardosinone (HY-N0380) .

HY-N12843

2-Deoxokanshone M Nardosinone acid	Natural Products Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae Source Classification	Drug Metabolite
2-Deoxokanshone M (Nardosinone acid) is a degradation product of Nardosinone (HY-N0380) and has potent vasodilatory activity .

HY-113412AR

3-Methylhistamine dihydrochloride (Standard)	Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
3-Methylhistamine (dihydrochloride) (Standard) is the analytical standard of 3-Methylhistamine (dihydrochloride). This product is intended for research and analytical applications. 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice .

HY-113137R

N2,N2-Dimethylguanosine (Standard)	Structural Classification Natural Products Other disease Disease markers Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
N2,N2-Dimethylguanosine (Standard) is the analytical standard of N2,N2-Dimethylguanosine. This product is intended for research and analytical applications. N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.

HY-N16427

2,3,-Dihydroxybenzoylserine 2,3-Dihydroxy-N-benzoylserine	Microorganisms Ketones, Aldehydes, Acids Source Classification	Endogenous Metabolite
2,3,-Dihydroxybenzoylserine (2,3-Dihydroxy-N-benzoylserine) is a conjugate of 2,3-dihydroxybenzoic acid and serine. 2,3,-Dihydroxybenzoylserine can be isolated from the culture of E.coli. 2,3,-Dihydroxybenzoylserine is a growth factor with growth-promoting activity in multiple aromatic auxotrophs such as E.coli KI2, strain AB2830. 2,3,-Dihydroxybenzoylserine is a degradation product of biological active compounds .

HY-B0300R

Penicillamine (Standard) D-(-)-Penicillamine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Cuproptosis Reference Standards Drug Metabolite
Penicillamine (Standard) is the analytical standard of Penicillamine. This product is intended for research and analytical applications. Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine increases free copper and increases oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-W012575R

2,4-Dihydroxybenzoic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS)
2,4-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,4-Dihydroxybenzoic acid (HY-W012575). This product is intended for research and analytical applications. 2,4-Dihydroxybenzoic acid is a degradation product of acid cherry anthocyanins during in vitro cell culture and an analogue of coenzyme Q precursor molecules. 2,4-Dihydroxybenzoic acid can improve the related symptoms of kidney diseases caused by ADCK4/Coq6 deficiency .

HY-N7495R

all-trans-Anhydro Retinol (Standard) Anhydrovitamin A (Standard)	Structural Classification Terpenoids Diterpenoids Endogenous metabolite Source Classification	Reference Standards Drug Metabolite
all-trans-Anhydro Retinol (Standard) (Anhydrovitamin A (Standard)) is the analytical standard of all-trans-Anhydro Retinol (HY-N7495). This product is intended for research and analytical applications. all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

HY-N7782

Arborinone	Triterpenes Structural Classification Iris tenuifolia Pall. Iridaceae Terpenoids Plants Source Classification	Others
Arborinone is a diagenetic degradation product.

HY-N17882

Hydroxysaikosaponin A Bupleuroside III	Structural Classification Sonchus asper (L.) Hill Terpenoids Umbelliferae Plants Pentacyclic Triterpenoids Source Classification	Drug Derivative
Hydroxysaikosaponin A (Bupleuroside III) is the acid hydrolysis degradation product of Saikosaponin A (HY-N0246) .

HY-N18055

Derritol	Structural Classification Leguminosae Lignans Phenylpropanoids Plants Derris elliptica (Roxb.) Benth. Source Classification	Drug Derivative
Derritol is a rotenone degradation product formed by the loss of C-6 and C-6a carbons from Rotenone (HY-B1756) .

HY-N13193

Pterosin A-2-O-glucoside	Pteridium caudatum Maxon Plants Saccharides Pteridiaceae Monosaccharides Source Classification	Others
Pterosin A-2-O-glucoside is a sesquiterpene glucoside. Pterosin A-2-O-glucoside might be a degradation product of an illudanetype diglucoside .

HY-113281

5-Hydroxyhexanoic acid	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
5-Hydroxyhexanoic acid is a normal monohydroxy carboxylic acid degradation product of fatty acids with medium chain lengths (particularly hexanoic acid). 5-Hydroxyhexanoic acid functions as a predictor of early renal functional decline in type 2 diabetes with microalbuminuria .

HY-N16643

7-O-Ethylepirosmanol Epirosmanol ethyl ether	Structural Classification Paramacrolobium coeruleum (Taub.) J.Léonard Labiatae Phenols Polyphenols Plants Source Classification	Others
7-O-Ethylepirosmanol (Epirosmanol ethyl ether) (Compound 6b) is the derivative of Epirosmanol (HY-111898). 7-O-Ethylepirosmanol is the degradation product of Carnosol (HY-N0643), the main antioxidant component in rosemary .

HY-N9715

4-Chloropinselin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Herbicide
4-Chloropinselin is a chlorine-containing xanthone herbicide that can be isolated from Alternaria sonchi. 4-Chloropinselin is a biosynthetic precursor or degradation product of chloromonilicin and exhibits phytotoxic and antimicrobial activity. 4-Chloropinselin can inhibit the growth of weeds such as field sowthistle and suppress the proliferation of certain microorganisms .

HY-N18965

Formyline	Structural Classification Alkaloids Pyrrole Alkaloids Animals Source Classification	Biochemical Assay Reagents
Formyline (Compound 8) is a Maillard reaction product (glycated compound). Formyline is an advanced glycation end product formed by the reaction of lysine with 3-deoxypentosone, pentose, disaccharide degradation products or glucuronic acid. Formyline is commonly found in heat-processed foods such as milk, baked goods and beer, and can serve as a characteristic marker for food processing .

HY-W750682

β-Carotene 5,6-epoxide	Natural Products Microorganisms Source Classification	Drug Derivative
β-Carotene 5,6-epoxide, a carotenoid, is a degradation product of β-carotene. β-Carotene 5,6-epoxide can be found in isolated chloroplasts. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W450115

USF 2550A	Structural Classification Natural Products Microorganisms Source Classification	Reactive Oxygen Species (ROS)
USF 2550A is a class of fungus-derived 2-pyran compound with DPPH free radical scavenging activity. USF 2550A binds to DPPH free radicals in organic solvents to form adducts, thereby achieving free radical scavenging; in acetate buffer, the formed adducts undergo degradation, and the degradation products can continuously scavenge free radicals. USF 2550A can be used in antioxidant-related research .

Cat. No.	Product Name	Chemical Structure

HY-W017386S

3-Methyl-2-oxovaleric acid-d8 sodium
3-Methyl-2-oxovaleric acid-d₈ sodium is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-79602S1

p-Toluenesulfonamide-15N
p-Toluenesulfonamide- ¹⁵N is the ¹⁵N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-B0300S

Penicillamine-d3
Penicillamine-d₃ is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.

HY-W142446S

2,6-Dichlorobenzamide-3,4,5-d3
2,6-Dichlorobenzamide-3,4,5-d₃ is the deuterium labeled 2,6-Dichlorobenzamide (HY-W142446). 2,6-Dichlorobenzamide is a herbicide degradation product that is relatively difficult to degrade .

HY-W018171S2

3,5,6-Trichloro-2-pyridinol-13C3
3,5,6-Trichloro-2-pyridinol- ¹³C₃ (TCPy- ¹³C₃) is the ¹³C-labeled 3,5,6-Trichloro-2-pyridinol (HY-W018171). 3,5,6-Trichloro-2-pyridinol (TCPy) is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and Chlorpyrifos-methyl .

HY-W743390

Propylene thiourea-d6
4-Methylimidazolidine-2-thione-d₆ (4-Methylimidazolidine-2-thione-d₆) is deuterium labeled 4-Methylimidazolidine-2-thione. Propylene thiourea is one of the main degradation products of Propineb (HY-119630) in animals, plants and during processing .

HY-W777582

4-tert-Octylphenol monoethoxylate-13C6

4-tert-Octylphenol monoethoxylate- ¹³C₆ is the ¹³C labeled isotope of 4-tert-Octylphenol monoethoxylate (HY-W777582) . 4-tert-Octylphenol monoethoxylate is an alkylphenolethoxylate (APE) and a degradation product of non-ionic surfactants (such as 4-tert-octylphenol polyethoxylate). 4-tert-Octylphenol monoethoxylate also possesses non-steroidal estrogenic activity. Additionally, 4-tert-Octylphenol monoethoxylate has been found in wastewater effluent .

HY-W010593S

Ethylenethiourea-d4
Ethylenethiourea-d₄ is the deuterium labeled Ethylenethiourea . Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active .

HY-23331S

Propylene thiourea-d3
4-Methylimidazolidine-2-thione-d₃ (4-Methylimidazolidine-2-thione-d₃) is deuterium labeled 4-Methylimidazolidine-2-thione. Propylene thiourea is one of the main degradation products of Propineb (HY-119630) in animals, plants and during processing .

HY-W042337S

3-Methyl-4-nitrophenol-d3

3-Methyl-4-nitrophenol-d₃ is the deuterium labeled 3-Methyl-4-nitrophenol (HY-W042337). 3-Methyl-4-nitrophenol, an environmental contaminant, is a well-known constituent of diesel exhaust particles and degradation products of insecticide fenitrothion. 3-Methyl-4-nitrophenol can induce nasal epithelial cell apoptosis and increase the permeability of the nasal epithelial barrier. 3-Methyl-4-nitrophenol is also toxic to the female reproductive system.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

degradation+product

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products