4-Chloropinselin
4-Chloropinselin is a chlorine-containing xanthone herbicide that can be isolated from Alternaria sonchi. 4-Chloropinselin is a biosynthetic precursor or degradation product of chloromonilicin and exhibits phytotoxic and antimicrobial activity. 4-Chloropinselin can inhibit the growth of weeds such as field sowthistle and suppress the proliferation of certain microorganisms.
For research use only. We do not sell to patients.
- CAS No.: 104022-83-5
- Formula: C16H11ClO6
- Molecular Weight:334.71
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 104022-83-5
-
Molecular Weight 334.71
-
Formula C16H11ClO6
-
SMILES
O=C(C(C(O)=CC(Cl)=C1OC2=CC(C)=CC(O)=C23)=C1C3=O)OC
-
Structure Classification
-
Initial Source
Alternaria sonchi S-102
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
-
Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Chloropinselin Related Classifications
HY-N9715 Related Classifications
Powered by Bioz