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Cat. No.: HY-N12843

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2-Deoxokanshone M

(Synonyms: Nardosinone acid)

2-Deoxokanshone M (Nardosinone acid) is a degradation product of Nardosinone (HY-N0380) and has potent vasodilatory activity.

For research use only. We do not sell to patients.

CAS No.: 53859-07-7
Formula: C₁₂H₁₆O₂
Molecular Weight:192.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

2-Deoxokanshone M Chemical Structure

CAS No.: 53859-07-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

2-Deoxokanshone M (Nardosinone acid) is a degradation product of Nardosinone (HY-N0380) and has potent vasodilatory activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>50 μM Compound: 10	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method	[PMID: 22079762]

Chemical Information

CAS No. 53859-07-7
Molecular Weight 192.25
Formula C₁₂H₁₆O₂
SMILES

C[C@@]12C(C(CC(C2)=O)=O)=CCC[C@H]1C
Synonyms

Nardosinone acid
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xue BX, et al. Degradation Profiling of Nardosinone at High Temperature and in Simulated Gastric and Intestinal Fluids. Molecules. 2023 Jul 13;28(14):5382. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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