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Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.

For research use only. We do not sell to patients.

Ethylenethiourea Chemical Structure

Ethylenethiourea Chemical Structure

CAS No. : 96-45-7

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Description

Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active[1][2].

In Vitro

Ethylenethiourea is stable at elevated temperature over a wide pH range[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ethylenethiourea (10-80 mg/kg; p.o.) is teratogenic in rats[1].
Ethylenethiourea (5-500 ppm; in the diet; 12 month) induces thyroid carcinomas in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Virgin Wistar female rats[1]
Dosage: 0, 5, 10, 20, 40 or 80 mg/kg
Administration: Oral administration, from 21-42 days before conception to pregnancy day 15, and on days 6-15 or 7-20 of pregnancy
Result: Induced meningoencephalocele, meningorrhagia, meningorrhea, hydrocephalus, obliterated neural canal, abnormal pelvic limb posture with equinovarus, and short or kinky tail after 10 mg/kg or more.
Molecular Weight

102.16

Formula

C3H6N2S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C1NCCN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Ethylenethiourea Related Classifications

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Ethylenethiourea
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HY-W010593
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