Zopiclone impurity-1
Based on 1 Customer Validation
Zopiclone impurity-1 (RP 29307) is an impurity and degradation product in the production process of zopiclone.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 43200-81-3
- Formula: C11H7ClN4O2
- Molecular Weight:262.66
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 43200-81-3
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Appearance Solid
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Molecular Weight 262.66
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Formula C11H7ClN4O2
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SMILES
C1=CC(=NC=C1Cl)N2C(C3=C(C2=O)N=CC=N3)O
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Synonyms
RP 29307
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (380.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8072 mL | 19.0360 mL | 38.0720 mL | 95.1801 mL |
| 5 mM | 0.7614 mL | 3.8072 mL | 7.6144 mL | 19.0360 mL | |
| 10 mM | 0.3807 mL | 1.9036 mL | 3.8072 mL | 9.5180 mL | |
| 15 mM | 0.2538 mL | 1.2691 mL | 2.5381 mL | 6.3453 mL | |
| 20 mM | 0.1904 mL | 0.9518 mL | 1.9036 mL | 4.7590 mL | |
| 25 mM | 0.1523 mL | 0.7614 mL | 1.5229 mL | 3.8072 mL | |
| 30 mM | 0.1269 mL | 0.6345 mL | 1.2691 mL | 3.1727 mL | |
| 40 mM | 0.0952 mL | 0.4759 mL | 0.9518 mL | 2.3795 mL | |
| 50 mM | 0.0761 mL | 0.3807 mL | 0.7614 mL | 1.9036 mL | |
| 60 mM | 0.0635 mL | 0.3173 mL | 0.6345 mL | 1.5863 mL | |
| 80 mM | 0.0476 mL | 0.2380 mL | 0.4759 mL | 1.1898 mL | |
| 100 mM | 0.0381 mL | 0.1904 mL | 0.3807 mL | 0.9518 mL |
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