Chitosan oligosaccharide (MW 2000)
Based on 1 Customer Validation
Chitosan oligosaccharide (MW 2000) is a natural oligomer derived from chitosan, with a molecular weight of 2000 Da. Chitosan oligosaccharide (MW 2000∼3000 Da) activates the P53, MAPK and NF-κB signaling pathways. As an ideal immunopotentiator, chitosan oligosaccharide is mainly used as a feed additive in aquaculture.
For research use only. We do not sell to patients.
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
Chitosan oligosaccharide (MW 2000∼3000 Da) activates the MAPK, NF-κB and p53 signaling pathways in head kidney macrophages of blunt snout bream in a time-dependent manner within 4-16 h[1].
Chitosan oligosaccharide (MW 2000∼3000 Da) at a concentration of 20 µg/mL for 16 h significantly induces apoptosis in head kidney macrophages of blunt snout bream[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:blunt snout bream (Megalobrama amblycephala) head kidney macrophages
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Concentration:20 µg/mL
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Incubation Time:16 h
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Result:Exhibited the highest level of apoptosis (both early apoptosis labeled by Annexin V-FITC and late apoptosis labeled by PI) compared to lower molecular weight COS groups and the control group.
Chemical Information
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Appearance Solid
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SMILES
[Chitosan oligosaccharide (MW 2000)]
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Synonyms
COS (MW 2000)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
DMSO : 40 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)