Emtricitabine S-oxide
Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
For research use only. We do not sell to patients.
- CAS No.: 152128-77-3
- Formula: C8H10FN3O4S
- Molecular Weight:263.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Reverse Transcriptase |
HIV |
Emtricitabine, an antiretroviral agent is used to evaluate degradation pathways under different stress conditions in order to identify degradation products as prescribed by ICH guidelines. Emtricitabine degrades over 51%, 13% and 53% during acid, base and oxidative degradation respectively followed by formation of three major degradation products (Degradant-I to Degradant-III)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 152128-77-3
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Molecular Weight 263.25
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Formula C8H10FN3O4S
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SMILES
O=C1N=C(N)C(F)=CN1[C@@H](O[C@H]2CO)CS2=O
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Synonyms
Emtricitabine sulfoxide; Emtricitabine Degradant-III
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)