1. Anti-infection
  2. HIV
    Reverse Transcriptase
  3. Emtricitabine S-oxide

Emtricitabine S-oxide (Synonyms: Emtricitabine sulfoxide; Emtricitabine Degradant-III)

Cat. No.: HY-100096
Handling Instructions

Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.

For research use only. We do not sell to patients.

Emtricitabine S-oxide Chemical Structure

Emtricitabine S-oxide Chemical Structure

CAS No. : 152128-77-3

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Description

Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.

IC50 & Target[1]

Reverse Transcriptase

 

HIV

 

In Vitro

Emtricitabine, an antiretroviral agent is used to evaluate degradation pathways under different stress conditions in order to identify degradation products as prescribed by ICH guidelines. Emtricitabine degrades over 51%, 13% and 53% during acid, base and oxidative degradation respectively followed by formation of three major degradation products (Degradant-I to Degradant-III)[1].

Molecular Weight

263.25

Formula

C₈H₁₀FN₃O₄S

CAS No.

152128-77-3

SMILES

O=C1N=C(N)C(F)=CN1[[email protected]@H](O[[email protected]]2CO)CS2=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Emtricitabine S-oxide
Cat. No.:
HY-100096
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