1-Oxo Ibuprofen
1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a potential impurity in the formulation of Ibuprofen (HY-78131). Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2, with IC50 values of 13 μM and 370 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 65813-55-0
- Formula: C13H16O3
- Molecular Weight:220.26
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
1-Oxo Ibuprofen is a major transformation product of Ibuprofen generated during the ozonation water treatment process, formed by the further oxidation of the hydroxyl group in 1-OH-IBU into a ketone group. During the ozonation reaction, the concentration of 1-Oxo Ibuprofen peaks at 60 minutes, accounting for approximately 3% of the initial Ibuprofen concentration, and then gradually decreases, indicating that it can be further degraded and transformed by ozone. Research on 1-Oxo Ibuprofen falls within the fields of environmental chemistry and wastewater treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 65813-55-0
-
Molecular Weight 220.26
-
Formula C13H16O3
-
SMILES
O=C(O)C(C)C1=CC=C(C(C(C)C)=O)C=C1
-
Synonyms
Ibuprofen EP impurity J
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1-Oxo Ibuprofen Related Classifications
HY-121899 Related Classifications
Powered by Bioz