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Penicillamine (Synonyms: D-(-)-Penicillamine)

Cat. No.: HY-B0300 Purity: ≥98.0%
Handling Instructions

Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics.

For research use only. We do not sell to patients.

Penicillamine Chemical Structure

Penicillamine Chemical Structure

CAS No. : 52-67-5

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Solution
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
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Estimated Time of Arrival: December 31
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100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Penicillamine

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. Target: Others Penicillamine is used as an antirheumatic and as a chelating agent in Wilson's disease and is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of penicillamine. Penicillamine also reduces excess cystine excretion in cystinuria. The mechanism of action of penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, Penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, Penicillamine in vitro depresses T-cell activity but not B-cell activity [1-3].

Clinical Trial
Molecular Weight

149.21

Formula

C5H11NO2S

CAS No.
SMILES

N[[email protected]](C(C)(S)C)C(O)=O

Structure Classification
Source

Penicillium

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (837.75 mM; ultrasonic and warming and heat to 60°C)

DMSO : 1.43 mg/mL (9.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.7020 mL 33.5098 mL 67.0196 mL
5 mM 1.3404 mL 6.7020 mL 13.4039 mL
10 mM 0.6702 mL 3.3510 mL 6.7020 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: ≥98.0%

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Product Name:
Penicillamine
Cat. No.:
HY-B0300
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