p-Toluenesulfonamide (Standard)
p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 70-55-3
- Formula: C7H9NO2S
- Molecular Weight:171.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 70-55-3
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Molecular Weight 171.22
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Formula C7H9NO2S
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SMILES
O=S(C1=CC=C(C)C=C1)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[3]. Tian YM, et al. A p-toluenesulfonamide-modified benzo[h]chromene hydrazone: Fluorescent turn-on detection of hypochlorite and its application to imaging the endoplasmic reticula of living cells and zebrafishes. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Aug 5;296:122669. [Content Brief]
[4]. Ajibola A, et al. Benzosulfonamides in wastewater: method development, occurrence and removal efficiencies. Chemosphere. 2015 Jan;119 Suppl:S21-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p-Toluenesulfonamide (Standard) Related Classifications
HY-79602R Related Classifications
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Keywords
- p-Toluenesulfonamide (Standard)
- 70-55-3
- Reference Standards
- Biochemical Assay Reagents
- Drug Derivative
- Drug Intermediate
- F344/N rats
- endoplasmic reticulum
- Chinese hamster lung cells
- Salmonella typhimurium
- hypochlorite
- B6C3F1/N mice
- F344/NTac rats
- micronuclei
- C57BL/6 mice
- malignant pleural effusion
- Inhibitor
- inhibitor
- inhibit