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Atorvastatin Epoxy Tetrahydrofuran Impurity 

Cat. No.: HY-136185
Handling Instructions

Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

For research use only. We do not sell to patients.

Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

CAS No. : 873950-19-7

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Description

Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589)[1]. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

In Vitro

Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.

Molecular Weight

449.47

Formula

C₂₆H₂₄FNO₅

CAS No.

873950-19-7

SMILES

O=C(C12C(C(C)C)(O)OC(O)(C3=CC=C(F)C=C3)C1(C4=CC=CC=C4)O2)NC5=CC=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Atorvastatin Epoxy Tetrahydrofuran ImpurityOthersoxidativedegradationproductsAtorvastatinorallyHMG-CoAreductasebloodlipidsInhibitorinhibitorinhibit

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Atorvastatin Epoxy Tetrahydrofuran Impurity
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HY-136185
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