Search Result

Results for "

o,p

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminopeptidase (1) Anaplastic lymphoma kinase (ALK) (1) Antibiotic (2) Apoptosis (7) Bacterial (7) Beta-lactamase (2) Biochemical Assay Reagents (10) CaMK (1) CD73 (2) CDK (1) Cholinesterase (ChE) (3) Deubiquitinase (1) DNA/RNA Synthesis (2) Drug Derivative (4) Endogenous Metabolite (1) ERK (2) Estrogen Receptor/ERR (6) Glucocorticoid Receptor (1) GLUT (1) Histone Acetyltransferase (1) Insecticide (4) Isotope-Labeled Compounds (8) JNK (1) MOFs (1) NF-κB (2) Nucleoside Antimetabolite/Analog (10) Opioid Receptor (8) PARP (1) PGE synthase (2) Phosphoramidites (2) Piezo Channel (1) Prostaglandin Receptor (1) Reference Standards (4) Small Interfering RNA (siRNA) (3) Survivin (1)
By Research Areas:	Cancer (27) Cardiovascular Disease (2) Endocrinology (3) Infection (7) Inflammation/Immunology (8) Metabolic Disease (4) Neurological Disease (9)
Oligonucleotides:	Nucleoside Analogs (9) Uridine (4) Inosine (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (1) Uracil (2) Phosphoramidites (2) siRNAs (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148789

Palazestrant OP-1250	Estrogen Receptor/ERR	Inflammation/Immunology Cancer
Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC₅₀ value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC₅₀ value of 1.4-1.6 nM. Palazestrant can inhibit ER ⁺/HER2 ⁺ cancer .

HY-13690

Mitotane 5 Publications Verification 2,4′-DDD; o,p'-DDD	Apoptosis	Cancer
Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-17593

Solithromycin 3 Publications Verification CEM-101; OP-1068	Bacterial Antibiotic	Infection
Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC₅₀s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis .

HY-109008

Nacubactam 2 Publications Verification OP0595 free acid	Beta-lactamase Bacterial	Infection
Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and C β-lactamases. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Nacubactam potentiates the antimicrobial activities of Piperacillin (HY-B1923), Cefepime (HY-B0692), and Meropenem (HY-13678) against CTX-M-15-positive Escherichia coli and KPC-positive Klebsiella pneumoniae .

HY-B0683

Limaprost 1 Publications Verification 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206	PGE synthase	Cardiovascular Disease Inflammation/Immunology
Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .

HY-W009004

Trilysine Lys-Lys-Lys; H-Lys-Lys-Lys-OH	Biochemical Assay Reagents	Others
Trilysine is a tripeptide and also a substrate for specific peptidases. Trilysine serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .

HY-U00177

GDP366 2 Publications Verification	Survivin	Cancer
GDP366, a dual inhibitor of survivin and *Op18*, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.

HY-W016188

1-Naphthyl acetate	Cholinesterase (ChE)	Others
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .

HY-137878

*2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid* PNP-α-NeuNAc	Biochemical Assay Reagents	Others
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) is a classic chromogenic substrate for neuraminidase. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid releases p-nitrophenol upon enzymatic hydrolysis, allowing quantification of enzyme activity and inhibitory effects via spectrophotometry. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) acts as a sialyl donor in the process of enzyme-catalyzed trans-sialylation .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Drug Derivative	Inflammation/Immunology
Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is a flavonoid glycoside present in Ginkgo biloba leaves, with antioxidant activity. Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside serves as the major antioxidant component in Shuxuening Injection .

HY-165607S

MCB-22-174	Piezo Channel Isotope-Labeled Compounds ERK CaMK	Metabolic Disease
MCB-22-174 is a deuterated Piezo1 agonist, with an EC₅₀ value of 6.28 μM. MCB-22-174 remarkably activates the CaMKII/ERK signaling pathway and initiates Ca ²⁺ influx in rMSCs. MCB-22-174 significantly decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. MCB-22-174 can effectively improve bone quality in hind-limb unloading (HU) model rats. MCB-22-174 can be used for the study of disuse osteoporosis (OP) .

HY-N5047

*Orientin-2''-O-p-trans-coumarate*	Others	Others
Orientin-2''-O-p-trans-coumarate is a flavonoid found in Trigonella foenum-graecum, with potent antioxidant activity .

HY-RS16219

SPP1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SPP1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

SPP1 Mouse Pre-designed siRNA Set A SPP1 Mouse Pre-designed siRNA Set A

HY-P1302

Orphanin FQ(1-11)	Opioid Receptor	Neurological Disease
Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a K_i of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (K_i>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice .

HY-121779

o,p'-DDE 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene	Insecticide	Endocrinology
o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC₅₀ value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).

HY-155993

YCH1899	PARP	Cancer
YCH1899 is an orally active PARP inhibitor, with an IC₅₀< 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib (HY-10162)-resistant and Talazoparib (HY-16106)-resistant Capan-1 cells (Capan-1/OP and Capan-1/TP cells) , with IC₅₀ values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats .

HY-P1317A

Nociceptin (1-13), amide TFA	Opioid Receptor	Neurological Disease
Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC₅₀ of 7.9 for mouse vas deferens and a K_i of 0.75 nM for binding to rat forebrain membranes .

HY-136978

OP-5244	CD73	Inflammation/Immunology Cancer
OP-5244 is a potent and orally active inhibitor of CD73, with an IC₅₀ of 0.25 nM. OP-5244 reverses immunosuppression through blocking of adenosine production, and has the potential for the cancer research .

HY-N1961

Ophiopogonin B OP-B	JNK Apoptosis	Cancer
Ophiopogonin B (OP-B) induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway. Ophiopogonin B is a saponin compound isolated from Radix Ophiopogonjaponicus .

HY-B1970

o,p'-DDT 2,4'-DDT	Insecticide Estrogen Receptor/ERR	Endocrinology
o,p'-DDT (2,4'-DDT) is a chlorinated organic pesticide with estrogenic activity. o,p'-DDT is persistent in the environment, can accumulate in organisms and disrupt the endocrine system. o,p'-DDT is used in agriculture as a pesticide, especially for controlling insect pests. The use of o,p'-DDT has led to toxic effects in organisms, raising widespread concern about its environmental and health effects. o,p'-DDT has also led to research into its long-term effects in ecosystems .

HY-B1970S

o,p'-DDT-d8 2,4'-DDT-d₈	Isotope-Labeled Compounds Insecticide	Others
o,p'-DDT-d₈ is the deuterium labeled o,p'-DDT .

HY-N2203A

*Vitexin2''-O-p-trans-coumarate*	Others	Others
Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ .

HY-W016188R

1-Naphthyl acetate (Standard)	Reference Standards Cholinesterase (ChE)	Others
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .

HY-13690R

Mitotane (Standard) 2,4′-DDD (Standard); o,p'-DDD (Standard)	Reference Standards Apoptosis	Cancer
Mitotane (Standard) is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-P10345

OP-145	Bacterial	Infection
OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .

HY-125839

OP-3633	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology
OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC₅₀ of 29 nM, with inhibition of GR transcriptional activity. OP-3633 exhibits low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism .

HY-125263

OP-1074	Estrogen Receptor/ERR	Cancer
OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC₅₀ values of 1.6 and 3.2 nM, respectively.

HY-N9238

*3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin*	Others	Others
3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin is a flavonoid that can be isolated from Quercus ilex .

HY-131244

ALK-IN-9	Anaplastic lymphoma kinase (ALK)	Cancer
ALK-IN-9 (compound 40) is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC₅₀s of <0.2 nM, <0.2 nM, 0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), KG-l cell (OP2-FGFR1), respectively .

HY-RS16853

Csf1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Csf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Csf1 Mouse Pre-designed siRNA Set A Csf1 Mouse Pre-designed siRNA Set A

HY-162633

USP1-IN-9	Deubiquitinase	Cancer
USP1-IN-9 (Compound 1m) is reversible and noncompetitive ubiquitin-specific proteases (USP1) inhibitors with an IC₅₀ of 8.8 nM, which is designed and synthesized to pyrido[2,3-d]pyrimidin-7(8H)-one derivative based on the disclosed structure of ML323(HY-17543) and KSQ-4279(HY-145471). USP1-IN-9 displays excellent USP1/UAF inhibition and exhibits strong antiproliferation effect in breast cancer cells. USP1-IN-9 can generate enhanced cell killing with PARP inhibitor olaparib(HY-10162) in olaparib-resistant MDA-MB-436/OP cells, which is promising for research in the field of cancer .

HY-P1302A

Orphanin FQ(1-11) TFA	Opioid Receptor	Neurological Disease
Orphanin FQ(1-11) TFA, a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a K_i of 55 nM. Orphanin FQ(1-11) TFA has no affinity for μ, δ, κ1 and κ3 receptors (K_i>1000 nM). Orphanin FQ(1-11) TFA is analgesic in CD-1 mice .

HY-136978A

OP-5244 sodium	CD73	Inflammation/Immunology Cancer
OP-5244 sodium is a potent and orally active inhibitor of CD73, with an IC₅₀ of 0.25 nM. OP-5244 sodium reverses immunosuppression through blocking of adenosine production, and has the potential for the cancer research .

HY-106110

OP-2507	Prostaglandin Receptor	Metabolic Disease
OP-2507 is a prostacyclin analog. OP-2507 can increase brain glucose levels in mice, suppress the breakdown of energy metabolism under hypoxic conditions, and has a protective effect against changes in cyclic nucleotides in hypoxic brain tissue (specifically, an increase in cyclic AMP and a decrease in cyclic GMP). OP-2507 provides protective effects against brain hypoxia and edema .

HY-125263B

(R)-OP-1074	Estrogen Receptor/ERR	Cancer
(R)-OP-1074 is an isomer of OP-1074 (HY-125263) and can serve as a control compound in experiments. OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC₅₀ values of 1.6 and 3.2 nM, respectively.

HY-13690S1

Mitotane-13C6 2,4′-DDD-¹³C₆; o,p'-DDD-¹³C₆	Apoptosis	Cancer
Mitotane- ¹³C₆ is the ¹³C labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-13690S3

Mitotane-13C12 2,4′-DDD-¹³C₁₂; o,p'-DDD-¹³C₁₂	Isotope-Labeled Compounds Apoptosis	Cancer
Mitotane- ¹³C₁₂ (2,4′-DDD- ¹³C₁₂) is ¹³C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-RS04914

FGFR1OP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FGFR1OP2 Human Pre-designed siRNA Set A contains three designed siRNAs for FGFR1OP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FGFR1OP2 Human Pre-designed siRNA Set A FGFR1OP2 Human Pre-designed siRNA Set A

HY-N12512

*6-O-p-Coumaroyl scandoside methyl ester*	Others	Inflammation/Immunology
6-O-p-Coumaroyl scandoside methyl ester is a compound that can be isolated from oldenlandia diffusa. 6-O-p-Coumaroyl scandoside methyl ester has anti-inflammatory activity .

HY-N2203

*Vitexin2''-O-p-coumarate*	Others	Others
Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ .

HY-N12980

*4-O-p-Coumaroylquinic acid*	Others	Others
4-O-p-Coumaroylquinic acid is a phenolic compound that can be isolated from Viburnum dilatatum .

HY-N2726

*6'-O-p-Hydroxybenzoylcatalposide*	Others	Others
6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .

HY-W145591

*Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin* Mono-6-O-(p-toluenesulfonyl)-alpha-cyclodextrin	Biochemical Assay Reagents	Others
Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145642

*Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin* Mono-2-O-(p-toluenesulfonyl)-gamma-cyclodextrin	Biochemical Assay Reagents	Others
Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145639

*Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin* Mono-2-o-(p-toluenesulfonyl)-alpha-cyclodextrin	Biochemical Assay Reagents	Others
Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145643

*Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin* Mono-6-O-(p-toluenesulfonyl)-gamma-cyclodextrin; Ts-γ-CD	Biochemical Assay Reagents	Others
Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145627

*Mono-2-O-(p-toluenesulfonyl)-β-cyclodextrin*	Biochemical Assay Reagents	Others
Mono-2-O-(p-toluenesulfonyl)-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W766965

*3,5-Di-O-p-chlorobenzoyl a-Floxuridine-13C,15N2*	Isotope-Labeled Compounds	Others
3,5-Di-O-p-chlorobenzoyl a-Floxuridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 3,5-Di-O-p-chlorobenzoyl a-Floxuridine.

HY-W411439

*1-O-p-Coumaroyl-β-D-glucose*	GLUT	Metabolic Disease
1-O-p-Coumaroyl-β-D-glucose can promote glucose uptake in HuH7 cells, and be be extracted from Luffa cylindrica (L.) Roem (sponge gourds) .

HY-W766967

*3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine-13C,15N2*	Isotope-Labeled Compounds	Others
3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine.

Cat. No.	Product Name	Type

HY-137878

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid

PNP-α-NeuNAc

Biochemical Assay Reagents

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) is a classic chromogenic substrate for neuraminidase. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid releases p-nitrophenol upon enzymatic hydrolysis, allowing quantification of enzyme activity and inhibitory effects via spectrophotometry. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) acts as a sialyl donor in the process of enzyme-catalyzed trans-sialylation .

HY-W145591

*Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin* Mono-6-O-(p-toluenesulfonyl)-alpha-cyclodextrin	Biochemical Assay Reagents
Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145642

*Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin* Mono-2-O-(p-toluenesulfonyl)-gamma-cyclodextrin	Biochemical Assay Reagents
Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145639

*Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin* Mono-2-o-(p-toluenesulfonyl)-alpha-cyclodextrin	Biochemical Assay Reagents
Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145643

*Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin* Mono-6-O-(p-toluenesulfonyl)-gamma-cyclodextrin; Ts-γ-CD	Biochemical Assay Reagents
Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145627

*Mono-2-O-(p-toluenesulfonyl)-β-cyclodextrin*	Biochemical Assay Reagents
Mono-2-O-(p-toluenesulfonyl)-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-113948

*2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl chloride*	Biochemical Assay Reagents
2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl chloride is a biochemical assay reagent.

HY-W776856

1,2:5,6-Di-O-isopropylidene-3-O-p-toluenesulfonyl-α-D-allofuranose

Biochemical Assay Reagents

1,2:5,6-Di-O-isopropylidene-3-O-p-toluenesulfonyl-α-D-allofuranose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W699077

3,4-Di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose

Biochemical Assay Reagents

3,4-Di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Target	Research Area

HY-W009004

Trilysine Lys-Lys-Lys; H-Lys-Lys-Lys-OH	Biochemical Assay Reagents	Others
Trilysine is a tripeptide and also a substrate for specific peptidases. Trilysine serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .

HY-P1302

Orphanin FQ(1-11)	Opioid Receptor	Neurological Disease
Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a K_i of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (K_i>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice .

HY-P1317A

Nociceptin (1-13), amide TFA	Opioid Receptor	Neurological Disease
Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC₅₀ of 7.9 for mouse vas deferens and a K_i of 0.75 nM for binding to rat forebrain membranes .

HY-P10345

OP-145	Bacterial	Infection
OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .

HY-P1302A

Orphanin FQ(1-11) TFA	Opioid Receptor	Neurological Disease
Orphanin FQ(1-11) TFA, a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a K_i of 55 nM. Orphanin FQ(1-11) TFA has no affinity for μ, δ, κ1 and κ3 receptors (K_i>1000 nM). Orphanin FQ(1-11) TFA is analgesic in CD-1 mice .

HY-W009004B

Trilysine TFA Lys-Lys-Lys TFA; H-Lys-Lys-Lys-OH TFA	Aminopeptidase	Others
Trilysine TFA is a tripeptide and also a substrate for specific peptidases. Trilysine TFA serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .

HY-P1317

Nociceptin (1-13), amide	Opioid Receptor	Neurological Disease
Nociceptin (1-13)，amide is a potent ORL1 receptor (opioid receptor-like 1 receptor，OP4) agonist with a pEC₅₀ of 7.9 for mouse vas deferens and a K_i of 0.75 nM for binding to rat forebrain membranes .

HY-P1301

[Arg14,Lys15]Nociceptin	Opioid Receptor	Neurological Disease
[Arg14,Lys15]Nociceptin is a highly potent and selective NOP receptor (ORL1; OP4) agonist, with an EC₅₀ of 1 nM. [Arg14,Lys15]Nociceptin displays high selectivity over opioid receptors, with IC₅₀s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively .

HY-P1300

[(pF)Phe4]Nociceptin(1-13)NH2	Opioid Receptor	Neurological Disease
[(pF)Phe4]Nociceptin(1-13)NH2 is a highly potent and selective NOP receptor (OP4) agonist, with a pK_i of 10.68 and a pEC₅₀ of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold) .

HY-P1301A

[Arg14,Lys15]Nociceptin TFA	Opioid Receptor	Neurological Disease
[Arg14,Lys15]Nociceptin TFA is a highly potent and selective NOP receptor (ORL1; OP4) agonist, with an EC₅₀ of 1 nM. [Arg14,Lys15]Nociceptin TFA displays high selectivity over opioid receptors, with IC₅₀s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively .

HY-P1300A

[(pF)Phe4]Nociceptin(1-13)NH2 TFA	Opioid Receptor	Neurological Disease
[(pF)Phe4]Nociceptin(1-13)NH2 TFA is a highly potent and selective NOP receptor (OP4) agonist, with a pK_i of 10.68 and a pEC₅₀ of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 TFA displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Ginkgo biloba Disease Research Fields Source Classification	Drug Derivative
Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is a flavonoid glycoside present in Ginkgo biloba leaves, with antioxidant activity. Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside serves as the major antioxidant component in Shuxuening Injection .

HY-N5047

*Orientin-2''-O-p-trans-coumarate*	Flavonoids other families Classification of Application Fields Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Orientin-2''-O-p-trans-coumarate is a flavonoid found in Trigonella foenum-graecum, with potent antioxidant activity .

HY-N1961

Ophiopogonin B OP-B	Other Terpenoids Classification of Application Fields Terpenoids Plants Disease Research Fields Asparagaceae Juss. Source Classification Cancer	JNK Apoptosis
Ophiopogonin B (OP-B) induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway. Ophiopogonin B is a saponin compound isolated from Radix Ophiopogonjaponicus .

HY-N2203A

*Vitexin2''-O-p-trans-coumarate*	Flavonoids Flavones Leguminosae Plants Trigonella foenum-graecum Linn. Source Classification	Others
Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ .

HY-N9238

*3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin*	Flavonoids Flavones Plants Fagaceae Source Classification Croton argyratus Blume	Others
3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin is a flavonoid that can be isolated from Quercus ilex .

HY-N12512

*6-O-p-Coumaroyl scandoside methyl ester*	Iridoids Terpenoids Rubiaceae Plants Hedyotis diffusa Willd. Source Classification	Others
6-O-p-Coumaroyl scandoside methyl ester is a compound that can be isolated from oldenlandia diffusa. 6-O-p-Coumaroyl scandoside methyl ester has anti-inflammatory activity .

HY-N2203

*Vitexin2''-O-p-coumarate*	Flavonoids other families Classification of Application Fields Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ .

HY-N12980

*4-O-p-Coumaroylquinic acid*	Monophenols Viburnum dilatatum Thunb. Viburnaceae Phenols Plants Source Classification	Others
4-O-p-Coumaroylquinic acid is a phenolic compound that can be isolated from Viburnum dilatatum .

HY-N2726

*6'-O-p-Hydroxybenzoylcatalposide*	Catalpa ovata G. Don Iridoids Terpenoids Bignoniaceae Plants Source Classification	Others
6'-O-p-Hydroxybenzoylcatalposide is a Iridoids product that can be isolated from the leaves of Catalpa ovata G. Don. .

HY-W411439

*1-O-p-Coumaroyl-β-D-glucose*	Monophenols Simple Phenylpropanols Cucurbitaceae Phenols Phenylpropanoids Plants Luffa aegyptiaca Miller Source Classification	GLUT
1-O-p-Coumaroyl-β-D-glucose can promote glucose uptake in HuH7 cells, and be be extracted from Luffa cylindrica (L.) Roem (sponge gourds) .

HY-N10757

*Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside*	Anthocyans Flavonoids Vitis vinifera cv. Zalema Plants Vitaceae Source Classification	Others
Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside is a natural product that can be isolated from grapes .

HY-N1742

2''-O-Coumaroyljuglanin 2''-O-p-Cumaroyleuglanin; Kaempferol 3-O-[2′′-(E)-p-coumaroyl]-α-L-arabinofuranoside	Flavonoids Prunus spinosa L. Flavones Rosaceae Plants Source Classification	Others
2''-O-Coumaroyljuglanin (2''-O-p-Cumaroyleuglanin) is a flavonoid which can be isolated from the flowers of Prunus spinosa .

HY-125048

Racemomycin B 229-B; Streptothricin D	Natural Products Microorganisms Source Classification	Bacterial
Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.

HY-N17146

*6'-O-p-Hydroxybenzoylgastrodin*	Structural Classification Monophenols Cucurbitaceae Phenols Plants Lagenaria siceraria (Molina) Standl. Source Classification	Drug Derivative
6'-O-p-Hydroxybenzoylgastrodin is a natural phenolic compound.

HY-N9731

*6-O-p-Hydroxybenzoylglutinoside*	Structural Classification Catalpa bungei C. A. Mey. Phenols Bignoniaceae Plants Source Classification	NF-κB
6-O-p-Hydroxybenzoylglutinoside acts as a selective NF-κB inhibitor that suppresses the transcriptional activity of TNF-α-activated NF-κB (IC₅₀=52.78 μM). 6-O-p-Hydroxybenzoylglutinoside shows no significant inhibitory activity against sEH, AChE, or BChE. 6-O-p-Hydroxybenzoylglutinoside is a caged chlorinated iridoid glycoside identified from the seeds of Catalpa bungei (Manchurian catalpa) .

HY-N9775

*3'',4''-Di-O-p-Coumaroylquercitrin*	Flavonoids Flavones Rosaceae Crataegus pinnatifida Bge. Plants Source Classification	Others
3'',4''-Di-O-p-Coumaroylquercitrin is a natural product .

HY-N17005

*3-O-(p-Hydroxybenzoyl)serratriol*	Lycopodiaceae Structural Classification Palhinhaea cernua (L.) Vasc. & Franco Terpenoids Phenols Plants Pentacyclic Triterpenoids Source Classification	Others
3-O-(p-Hydroxybenzoyl)serratriol is a serratene-type triterpenoid compound with low cytotoxicity against cancer cells (IC₅₀ >100 μg/mL against three human cancer cell lines: K562, SMMC-7721, and SGC7901). 3-O-(p-Hydroxybenzoyl)serratriol can be naturally extracted from the whole plant of Palhinhaea cernua .

HY-N16993

*1-O-p-Coumaroyl-3-O-feruloylglycerol*	Structural Classification Liliaceae Lilium auratum Lindl. Phenols Polyphenols Plants Source Classification	Drug Derivative
1-O-p-Coumaroyl-3-O-feruloylglycerol is a natural phenylacetylene.

HY-N18220

*Naringenin-7-O-(3″,6″-di-O-p-E-coumaroyl)-β-glucopyranoside*	Structural Classification Flavonoids Phenols Polyphenols Quercus mongolica Fischer ex Ledebour Euphorbiaceae Plants Other Flavonoids Source Classification	Others
Naringenin-7-O-(3″,6″-di-O-p-E-coumaroyl)-β-glucopyranoside (Compound 7) is a flavonoid found in Cnidoscolus texanus. Naringenin-7-O-(3″,6″-di-O-p-E-coumaroyl)-β-glucopyranoside does not functionally modulate DNA topoisomerase I activity .

HY-N4196

*4-(4'-Hydroxyphenyl)-2-butanone4'-O-β-D-(2''-O-galloyl-6''-O-p-coumaroyl)glucopyranoside*	Polygonaceae Phenols Polyphenols Plants Rheum tanguticum Source Classification	Others
4-(4'-Hydroxyphenyl)-2-butanone4'-O-β-D-(2''-O-galloyl-6''-O-p-coumaroyl)glucopyranoside is a natural product .

HY-N17167

*Maltol 3-O-(5-O-p-coumaroyl)-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside* 3'''-Deoxyshimobashiraside A	Structural Classification Labiatae Other Phenylpropanoids Phenylpropanoids Plants Cremanthodium helianthus (Franch.) W. W. Sm. Source Classification	Drug Derivative
Maltol 3-O-(5-O-p-coumaroyl)-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (3'''-Deoxyshimobashiraside A) is a natural phenolic compound.

HY-N17771

*(6-O-p-Coumaroyl)-β-D-glucopyranosyl-2-O-(4-hydroxybenzoyl)-4-O-β-D-glucopyranosyl-6-hydroxyphenylacetate*	Structural Classification Impatiens balsamina Linn. Balsaminaceae Phenols Polyphenols Plants Source Classification	Endogenous Metabolite
(6-O-p-Coumaroyl)-β-D-glucopyranosyl-2-O-(4-hydroxybenzoyl)-4-O-β-D-glucopyranosyl-6-hydroxyphenylacetate is a selective α-glucosidase inhibitor (IC₅₀=10.53 μg/mL) with anti-hepatic fibrosis and anti-diabetic properties. It also inhibits the growth of mouse hepatic stellate cells (t-HSC/Cl-6) with an IC₅₀ of 109.2 μg/mL. (6-O-p-Coumaroyl)-β-D-glucopyranosyl-2-O-(4-hydroxybenzoyl)-4-O-β-D-glucopyranosyl-6-hydroxyphenylacetate can be isolated from the ester derivatives of Impatiens balsamina L. flowers. (6-O-p-Coumaroyl)-β-D-glucopyranosyl-2-O-(4-hydroxybenzoyl)-4-O-β-D-glucopyranosyl-6-hydroxyphenylacetate can be used in research related to hepatic fibrosis and type 2 diabetes.

HY-N12512A

Oldenlandoside I (E)-6-O-p-Coumaroyl scandoside methyl ester	Structural Classification Iridoids Terpenoids Rubiaceae Plants Hedyotis diffusa Willd. Source Classification

Species:	Human (8) Mouse (1)
Tag:	His (8) Tag Free (1) GST (1)
Source:	Sf9 insect cells (1) P. pastoris (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71786

	Osteopontin/OPN Protein, Mouse (P.pastoris, His) 3 Publications Verification Spp1; Eta-1; Op; Spp-1; Osteopontin; 2AR; Minopontin; Secreted phosphoprotein 1; SPP-1	Mouse	P. pastoris
	Osteopontin/OPN Protein, a crucial non-collagenous bone protein, binds strongly to hydroxyapatite, integral to the mineralized matrix.It likely plays a vital role in mediating cell-extracellular matrix interactions.Moreover, as a cytokine, OPN efficiently induces interferon-gamma and interleukin-12 production while inhibiting interleukin-10, pivotal in promoting type I immunity.Osteopontin/OPN Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Osteopontin/OPN protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P7008

	BMP-7 Protein, Human 5 Publications Verification rHuBMP-7; OP-1	Human	E. coli
	Bone morphogenetic protein 7 (BMP-7) is a polymorphic ligand protein belonging to the TGFβ family. BMP-7 is involved in regulating the proliferation, invasion and migration of cancer cells and is associated with a variety of human tumors. BMP-7 binds ALK2 or ACVR2A/BMPR2 excitation signal, which is terminated by SMADs regulation. BMP-7 is involved in the BMP-7-SMad1/5/9 signaling pathway, which is associated with the epithelial-mesenchymal transition (EMT) process. BMP-7 also eliminates vascular inflammation, maintains vascular integrity, reduces vascular calcification, and stimulates in situ phosphate ossification deposition. The total length of human BMP-7 protein is 431 amino acids (M1-H431), with 4 glycosylation domains. BMP-7 Protein, Human has a total length of 139 amino acids (S293-H431), is expressed in E. coli cells.

HY-P7008A

	BMP-7 Protein, Human (His) rHuBMP-7; OP-1	Human	E. coli
	Bone morphogenetic protein 7 (BMP-7) is a polymorphic ligand protein belonging to the TGF-β family. BMP-7 is involved in regulating the proliferation, invasion and migration of cancer cells and is associated with a variety of human tumors. BMP-7 binds ALK2 or ACVR2A/BMPR2 excitation signal, which is terminated by SMADs regulation. BMP-7 is involved in the BMP-7-SMad1/5/9 signaling pathway, which is associated with the epithelial-mesenchymal transition (EMT) process. BMP-7 also eliminates vascular inflammation, maintains vascular integrity, reduces vascular calcification, and stimulates in situ phosphate ossification deposition.

HY-P700030AF

	Animal-Free BMP-7 Protein, Human (His) Osteogenic Protein-1; OP-1	Human	E. coli
	BMP-7 protein is an important member of the TGF-β superfamily and is critical in embryogenesis, hematopoiesis, neurogenesis and bone morphogenesis. It activates canonical BMP signaling through ACVR1 and ACVR2A, phosphorylates and activates ACVR1, which in turn phosphorylates SMAD1/5/8 for target gene transcriptional regulation. Animal-Free BMP-7 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-7 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P700031AF

	Animal-Free BMP-8a Protein, Human (His) BMP-8; OP-2; Osteogenic Protein-2	Human	E. coli
	BMP-8 is a pleiotropic ligand protein act as a reproductive system regulator, enriched in the ovary. BMP-8 is encoded by a pair of genes BMP8A and BMP8B, belonging to TNF-β family. BMP-8A activates the SMAD1/5/8 and the SMAD2/3 pathways in granulosa cells, to inhibit gonadotropin-induced progesterone production and steroidogenesis-related gene expression. BMP-8A also involves in Nrf2 phosphorylation in cancer cells to promote survival and drug resistance. BMP-8a Protein, Human is 402 a.a. with 2 glycosylation domains. Animal-Free BMP-8a Protein, Human (His) is a animal free recombinant human protein produced in E. coli cells, with 139 a.a. (A264-H402) and C-terminal His-tag.This product is for cell culture use only.

HY-P71121

	Stathmin Protein, Human (C-His) Stathmin; Leukemia-Associated Phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18	Human	E. coli
	Stathmin proteins critically regulate the microtubule filament system by actively destabilizing microtubules, inhibiting assembly, and promoting disassembly. Phosphorylation of Ser-16 is critical for axon formation during neurogenesis, highlighting its importance in neuronal development. Stathmin Protein, Human (C-His) is the recombinant human-derived Stathmin protein, expressed by E. coli , with C-6*His labeled tag.

HY-P71121A

	Stathmin Protein, Human (His) "Stathmin; Leukemia-Associated Phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18 "	Human	E. coli
	Stathmin Protein, a widely distributed cytosolic phosphoprotein, integrates regulatory signals and destabilizes microtubules, crucial for their assembly and disassembly. It exhibits broad expression in various tissues, highlighting its versatile role in cellular processes. Stathmin Protein, Human (His) is the recombinant human-derived Stathmin protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76927

	FGFR1OP Protein, Human (sf9, His-GST) Centrosomal protein 43; FGFR1 oncogene partner; CEP43; FOP	Human	Sf9 insect cells
	FGFR1OP is critical for microtubule dynamics, anchoring microtubules at centrosomes, which is critical for cell organization. It plays an integral role in cilia formation and helps control the complex process of cilia formation. FGFR1OP Protein, Human (sf9, His-GST) is the recombinant human-derived FGFR1OP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P700032AF

	Animal-Free BMP-8b Protein, Human (His) Bone Morphogenetic Protein 8b; Osteogenic Protein 2; OP-2; BMP8	Human	E. coli
	BMP-8 is a pleiotropic ligand protein act as a reproductive system regulator, enriched in the ovary. BMP-8 is encoded by a pair of genes BMP8A and BMP8B, belonging to TNF-β family. BMP-8B is secreted by brown/beige adipocytes and enhances energy dissipation, serves as a potential targets in obesity. BMP-8B also caspase-3 and -9 activation in pancreatic cancer cell, as well as decreasing mitochondrial membrane potential to induce apoptosis. BMP-8b Protein, Human is 402 a.a. with 2 glycosylation domains. Animal-Free BMP-8a Protein, Human (His) is a animal free recombinant human protein produced in E. coli cells, with 139 a.a. (A264-H402) and N-terminal His-tag.This product is for cell culture use only.

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Cat. No.	Product Name	Chemical Structure

HY-165607S

MCB-22-174

MCB-22-174 is a deuterated Piezo1 agonist, with an EC₅₀ value of 6.28 μM. MCB-22-174 remarkably activates the CaMKII/ERK signaling pathway and initiates Ca ²⁺ influx in rMSCs. MCB-22-174 significantly decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. MCB-22-174 can effectively improve bone quality in hind-limb unloading (HU) model rats. MCB-22-174 can be used for the study of disuse osteoporosis (OP) .

HY-B1970S

o,p'-DDT-d8
o,p'-DDT-d₈ is the deuterium labeled o,p'-DDT .

HY-13690S1

Mitotane-13C6

Mitotane- ¹³C₆ is the ¹³C labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-13690S3

Mitotane-13C12

Mitotane- ¹³C₁₂ (2,4′-DDD- ¹³C₁₂) is ¹³C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-W766965

*3,5-Di-O-p-chlorobenzoyl a-Floxuridine-13C,15N2*
3,5-Di-O-p-chlorobenzoyl a-Floxuridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 3,5-Di-O-p-chlorobenzoyl a-Floxuridine.

HY-W766967

*3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine-13C,15N2*
3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 3,5-Di-O-p-chlorobenzoyl a,b-Floxuridine.

HY-W766046

*2'-Deoxy-3',5'-di-O-p-toluoyl Uridine-13C,15N2*
2'-Deoxy-3',5'-di-O-p-toluoyl Uridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 2'-Deoxy-3',5'-di-O-p-toluoyl Uridine.

HY-B0683S

Limaprost-d3
Limaprost-d₃ (17α,20-dimethyl-δ2-PGE1-d₃) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .

HY-13690S2

Mitotane-d8

Mitotane-d₈ is the deuterium labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-W766964

*3,5-Di-O-p-chlorobenzoyl Floxuridine-13C,15N2*
3,5-Di-O-p-chlorobenzoyl Floxuridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 3,5-Di-O-p-chlorobenzoyl Floxuridine (HY-W778028).

Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (1) ICC/IF (1) IP (1) WB (3) ELISA (2)
Isotype:	IgG (1) IgG2a (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87491

	FGFR1OP2 Antibody (YA7178)	WB, ELISA
	FGFR1OP2 Antibody (YA7178) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FGFR1OP2.

HY-P82810

	BMP7 Antibody (YA2555) Bmp7; Bone morphogenetic protein 7; Eptotermin alfa; OP 1; Osteogenic protein 1	WB, IP	Human, Mouse, Rat
	BMP7 Antibody (YA2555) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BMP7.

HY-P85937

	Stathmin 1 Antibody (YA5629) C1orf215; Lag; LAP 18; LAP18; Leukemia associated phosphoprotein p18; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; OP 18; Op18; p18; p19; Phosphoprotein 19; Phosphoprotein p19; pp17; pp19; PR22; Pr22 protein; Prosolin; Protein Pr22; SMN; Stathmin; Stathmin1; STMN 1; Stmn1; STMN1_HUMAN	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Stathmin 1 Antibody (YA5629) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Stathmin 1.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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