1. Anti-infection
  2. Bacterial

Solithromycin (Synonyms: CEM-101; OP-1068)

Cat. No.: HY-17593 Purity: 99.81%
Data Sheet SDS Handling Instructions

Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.

For research use only. We do not sell to patients.
Solithromycin Chemical Structure

Solithromycin Chemical Structure

CAS No. : 760981-83-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $270 In-stock
2 mg $80 In-stock
5 mg $160 In-stock
10 mg $290 In-stock
50 mg $900 In-stock
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness. Target: Antibacterial Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations (IC50s) for Solithromycin inhibition of cell viability, protein synthesis, and growth rate were 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively.

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.1834 mL 5.9171 mL 11.8342 mL
5 mM 0.2367 mL 1.1834 mL 2.3668 mL
10 mM 0.1183 mL 0.5917 mL 1.1834 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

845.01

Formula

C₄₃H₆₅FN₆O₁₀

CAS No.

760981-83-7

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 32 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Solithromycin
Cat. No.:
HY-17593
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