1. Anti-infection
  2. Bacterial

Solithromycin (Synonyms: CEM-101; OP-1068)

Cat. No.: HY-17593 Purity: 99.81%
Handling Instructions

Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.

For research use only. We do not sell to patients.

Solithromycin Chemical Structure

Solithromycin Chemical Structure

CAS No. : 760981-83-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 323 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
2 mg USD 96 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 192 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 348 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 1080 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness. Target: Antibacterial Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations (IC50s) for Solithromycin inhibition of cell viability, protein synthesis, and growth rate were 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively.

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 32 mg/mL (37.87 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1834 mL 5.9171 mL 11.8342 mL
5 mM 0.2367 mL 1.1834 mL 2.3668 mL
10 mM 0.1183 mL 0.5917 mL 1.1834 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

845.01

Formula

C₄₃H₆₅FN₆O₁₀

CAS No.

760981-83-7

SMILES

C[[email protected]]([[email protected]](OC([[email protected]@](F)(C([[email protected]](C)[[email protected]]1O[[email protected]@](O[[email protected]](C)C[[email protected]@H]2N(C)C)([H])[[email protected]@H]2O)=O)C)=O)CC)(O3)[[email protected]]([[email protected]](C([[email protected]@H](C[[email protected]@]1(C)OC)C)=O)C)([H])N(CCCCN4C=C(C5=CC(N)=CC=C5)N=N4)C3=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Solithromycin
Cat. No.:
HY-17593
Quantity:

Solithromycin

Cat. No.: HY-17593