Orphanin FQ(1-11)
Based on 1 Customer Validation
Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 178249-41-7
- Formula: C49H75N15O14
- Molecular Weight:1098.21
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
![[Nphe1]Nociceptin(1-13)NH2](https://file.medchemexpress.com/product_pic/hy-p1320.gif)
![[Arg14,Lys15]Nociceptin](https://file.medchemexpress.com/product_pic/hy-p1301.gif)
![[(pF)Phe4]Nociceptin(1-13)NH2](https://file.medchemexpress.com/product_pic/hy-p1300.gif)
All Opioid Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 178249-41-7
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Appearance Solid
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Molecular Weight 1098.21
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Formula C49H75N15O14
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Color White to off-white
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Sequence Shortening
FGGFTGARKSA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (91.06 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Reinscheid RK, et al. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem. 1996;271(24):14163-14168. [Content Brief]
[2]. Rossi GC, et al. Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J Pharmacol Exp Ther. 1997;282(2):858-865. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.9106 mL | 4.5529 mL | 9.1057 mL | 22.7643 mL |
| 5 mM | 0.1821 mL | 0.9106 mL | 1.8211 mL | 4.5529 mL | |
| 10 mM | 0.0911 mL | 0.4553 mL | 0.9106 mL | 2.2764 mL | |
| 15 mM | 0.0607 mL | 0.3035 mL | 0.6070 mL | 1.5176 mL | |
| 20 mM | 0.0455 mL | 0.2276 mL | 0.4553 mL | 1.1382 mL | |
| 25 mM | 0.0364 mL | 0.1821 mL | 0.3642 mL | 0.9106 mL | |
| 30 mM | 0.0304 mL | 0.1518 mL | 0.3035 mL | 0.7588 mL | |
| 40 mM | 0.0228 mL | 0.1138 mL | 0.2276 mL | 0.5691 mL | |
| 50 mM | 0.0182 mL | 0.0911 mL | 0.1821 mL | 0.4553 mL | |
| 60 mM | 0.0152 mL | 0.0759 mL | 0.1518 mL | 0.3794 mL | |
| 80 mM | 0.0114 mL | 0.0569 mL | 0.1138 mL | 0.2846 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Orphanin FQ(1-11) Related Classifications
HY-P1302 Related Classifications
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