1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. UFP-101

UFP-101 

Cat. No.: HY-P1299
Handling Instructions

UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect.

For research use only. We do not sell to patients.

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UFP-101 Chemical Structure

UFP-101 Chemical Structure

CAS No. : 849024-68-6

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Description

UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[1][2].

In Vivo

UFP-101 elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST)[1].

Molecular Weight

1908.17

Formula

C₈₂H₁₃₈N₃₂O₂₁

CAS No.

849024-68-6

Sequence Shortening

Bn-GGGFTGARKSARKRKNQ-NH2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

UFP-101UFP101UFP 101Opioid Receptorselectivecompetitiveantidepressantforcedswimmingtestligand,Inhibitorinhibitorinhibit

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