6-O-p-Hydroxybenzoylglutinoside
6-O-p-Hydroxybenzoylglutinoside acts as a selective NF-κB inhibitor that suppresses the transcriptional activity of TNF-α-activated NF-κB (IC50=52.78 μM). 6-O-p-Hydroxybenzoylglutinoside shows no significant inhibitory activity against sEH, AChE, or BChE. 6-O-p-Hydroxybenzoylglutinoside is a caged chlorinated iridoid glycoside identified from the seeds of Catalpa bungei (Manchurian catalpa).
For research use only. We do not sell to patients.
- CAS No.: 202337-44-8
- Formula: C13H16O8
- Molecular Weight:300.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NF-κB 52.78 μM (IC50) |
6-O-p-Hydroxybenzoylglutinoside (compound 3) (1 h pretreatment; 20 h post TNF-α treatment) inhibits TNF-α-induced NF-κB transcriptional activity in HepG2 cells with an IC50 of 52.78 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 202337-44-8
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Molecular Weight 300.26
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Formula C13H16O8
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SMILES
O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COC(C1=CC=C(C=C1)O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-O-p-Hydroxybenzoylglutinoside Related Classifications
HY-N9731 Related Classifications
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