2. Vitamin D Related/Nuclear Receptor Anti-infection Membrane Transporter/Ion Channel PI3K/Akt/mTOR MAPK/ERK Pathway Apoptosis
  3. Estrogen Receptor/ERR Bacterial Sodium Channel PI3K JNK Akt Apoptosis
  4. Propylparaben sodium

Propylparaben sodium  (Synonyms: Propyl parahydroxybenzoate sodium; Propyl 4-hydroxybenzoate sodium)

製品番号: HY-N2026A 純度: 99.03%
COA 取扱説明書 Technical Support

Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury.

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Propylparaben sodium

Propylparaben sodium 構造式

CAS 番号 : 35285-69-9

容量 価格（税別） 在庫状況 数量
100 mg $25 在庫あり
500 mg $50 在庫あり
1 g $70 在庫あり
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10 g   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

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Propylparaben sodium 関連抗体

Top Publications Citing Use of Products

Estrogen Receptor/ERR アイソフォーム固有の製品をすべて表示:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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JNK1 JNK2 JNK3 JNK

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Akt Akt1 Akt2 Akt3

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製品説明

Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury[1][2][3][4][5].

体外実験

Propylparaben sodium shows weak estrogenic activity, with a potency approximately 30,000-fold less than 17β-estradiol[1].
Propylparaben sodium disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Propylparaben sodium 関連抗体
体内実験

Propylparaben (0-1% in diet; dietary; continuous; 28 days) sodium disrupts male reproductive function in immature rats, causing dose-dependent reductions in sperm parameters and serum testosterone[1].
Propylparaben (7.5 mg/kg; p.o.; daily for 8 months) sodium significantly alters the estrous cycle, hormone levels and ovarian reserve, and accelerated ovarian aging in mice[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Crj:Wistar rats (male, 19-21 days old, 52.5 g) fed with slightly modified AIN93G diet[1]
Dosage: 0; 0.01; 0.1; 1% in diet
Administration: dietary; continuous; 28 days
Result: Reduced final body weight slightly but significantly at 1.00% dietary concentration.
Decreased cauda epididymal sperm reserves and sperm concentrations in a dose-dependent manner.
Decreased daily sperm production (DSP) and sperm production efficiency in the testes in a dose-dependent manner.
Decreased serum testosterone concentration in a dose-dependent manner, with a significant reduction to 64.6% of the control value at the 1.00% dietary concentration.
Animal Model: Cycling wild-type female Swiss mice[5]
Dosage: 7.5 mg/kg
Administration: p.o.; daily for 8 months
Result: Significantly altered the estrous cycle, hormone levels and ovarian reserve.
Accelerated ovarian aging of female mice.
分子量

202.18

分子式

C10H11NaO3
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCC)C1=CC=C(O[Na])C=C1
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション

純度: 99.03%

COA (245 KB) HNMR (230 KB) LCMS (95 KB)

取扱説明書 (2659 KB)
参考文献
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Propylparaben sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propylparaben35285-69-9Propyl parahydroxybenzoatePropyl 4-hydroxybenzoateEstrogen Receptor/ERRBacterialSodium ChannelPI3KJNKAktApoptosisNa channelsNa+ channelsPhosphoinositide 3-kinasec-Jun N-terminal kinasePKBProtein kinase Boxidative stressestrus cyclesantral follicleJNK signaling pathwaysPI3K-AKT signaling pathwaysovarian reservespermandrogen receptorsestrogen receptorsInhibitorinhibitorinhibit

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製品名:
Propylparaben sodium
製品番号:
HY-N2026A
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