35285-69-9
Chemical Structure
Propylparaben sodium
Synonym(s): Propyl parahydroxybenzoate sodium; Propyl 4-hydroxybenzoate sodium
- CAS No.: 35285-69-9
- Formula:C10H11NaO3
- Molecular Weight:202.18
IUPAC Name: sodium 4-(propoxycarbonyl)phenolate
InChIKey: IXMINYBUNCWGER-UHFFFAOYSA-M
SMILES: O=C(OCCC)C1=CC=C(O[Na])C=C1
Biological Activity: Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury[1][2][3][4][5].
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Propylparaben sodium | 99.03% | Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury. | ||||||||||||||||||||
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Propylparaben sodium (Standard) | ≥98% | Propylparaben (Propyl parahydroxybenzoate) sodium (Standard) is the analytical standard of Propylparaben sodium (HY-N2026A). Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury. | ||||||||||||||||||||
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- [1]. Oishi S, et al. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol. 2002;40(12):1807-1813. [Content Brief]
- [2]. Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products. Int J Toxicol. 2008;27 Suppl 4:1-82. [Content Brief]
- [3]. Ji X, et al. Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury. Life Sci. 2004;74(24):3043-3052. [Content Brief]
- [4]. Yan W, et al. Chronic exposure to propylparaben at the humanly relevant dose triggers ovarian aging in adult mice. Ecotoxicol Environ Saf. 2022;235:113432. [Content Brief]
- [5]. Gal A, et al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019;89:100-106. [Content Brief]
