2. Vitamin D Related/Nuclear Receptor Anti-infection Membrane Transporter/Ion Channel PI3K/Akt/mTOR MAPK/ERK Pathway Apoptosis
  3. Estrogen Receptor/ERR Bacterial Sodium Channel PI3K JNK Akt Apoptosis
  4. Propylparaben sodium

Propylparaben sodium  (Synonyms: Propyl parahydroxybenzoate sodium; Propyl 4-hydroxybenzoate sodium)

Cat. No.: HY-N2026A Pureza: 99.03%
COA
SDS
Instrucciones de manejo Technical Support

Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury.

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Propylparaben sodium

Propylparaben sodium Estructura química

No. CAS : 35285-69-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Propylparaben sodium:

Propylparaben sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Propylparaben sodium

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Descripciòn

Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury[1][2][3][4][5].

In Vitro

Propylparaben sodium shows weak estrogenic activity, with a potency approximately 30,000-fold less than 17β-estradiol[1].
Propylparaben sodium disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Propylparaben sodium Related Antibodies
In Vivo

Propylparaben (0-1% in diet; dietary; continuous; 28 days) sodium disrupts male reproductive function in immature rats, causing dose-dependent reductions in sperm parameters and serum testosterone[1].
Propylparaben (7.5 mg/kg; p.o.; daily for 8 months) sodium significantly alters the estrous cycle, hormone levels and ovarian reserve, and accelerated ovarian aging in mice[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Crj:Wistar rats (male, 19-21 days old, 52.5 g) fed with slightly modified AIN93G diet[1]
Dosage: 0; 0.01; 0.1; 1% in diet
Administration: dietary; continuous; 28 days
Result: Reduced final body weight slightly but significantly at 1.00% dietary concentration.
Decreased cauda epididymal sperm reserves and sperm concentrations in a dose-dependent manner.
Decreased daily sperm production (DSP) and sperm production efficiency in the testes in a dose-dependent manner.
Decreased serum testosterone concentration in a dose-dependent manner, with a significant reduction to 64.6% of the control value at the 1.00% dietary concentration.
Animal Model: Cycling wild-type female Swiss mice[5]
Dosage: 7.5 mg/kg
Administration: p.o.; daily for 8 months
Result: Significantly altered the estrous cycle, hormone levels and ovarian reserve.
Accelerated ovarian aging of female mice.
Peso molecular

202.18

Fòrmula

C10H11NaO3
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCC)C1=CC=C(O[Na])C=C1
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación

Purity: 99.03%

SDS (476 KB)

COA (245 KB) HNMR (230 KB) LCMS (95 KB)

Instrucciones de manejo (2659 KB)
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Propylparaben sodium Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propylparaben35285-69-9Propyl parahydroxybenzoatePropyl 4-hydroxybenzoateEstrogen Receptor/ERRBacterialSodium ChannelPI3KJNKAktApoptosisNa channelsNa+ channelsPhosphoinositide 3-kinasec-Jun N-terminal kinasePKBProtein kinase Boxidative stressestrus cyclesantral follicleJNK signaling pathwaysPI3K-AKT signaling pathwaysovarian reservespermandrogen receptorsestrogen receptorsInhibitorinhibitorinhibit

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Nombre del producto:
Propylparaben sodium
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