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Results for "

Cyclohexane

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Antibiotic (4) Apoptosis (3) Arrestin (2) Autophagy (5) Bacterial (18) Biochemical Assay Reagents (7) CXCR (2) Drug-Linker Conjugates for ADC (1) EGFR (1) Endogenous Metabolite (2) Endothelin Receptor (2) ERK (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) Fungal (3) GHSR (1) Glucosidase (1) HCV (1) HIF/HIF Prolyl-Hydroxylase (3) IFNAR (1) Integrin (11) Isotope-Labeled Compounds (4) Ligands for E3 Ligase (5) MMP (2) NF-κB (1) Nuclear Factor of activated T Cells (NFAT) (1) Opioid Receptor (2) Oxytocin Receptor (1) Parasite (1) PD-1/PD-L1 (1) Phosphatase (1) PI3K (1) PROTAC Linkers (1) Proteasome (1) Raf (1) Ras (1) Reactive Oxygen Species (1) Somatostatin Receptor (4) STAT (1) Topoisomerase (1) Vasopressin Receptor (1) VEGFR (1)
By Research Areas:	Cancer (43) Cardiovascular Disease (5) Endocrinology (3) Infection (20) Inflammation/Immunology (13) Metabolic Disease (7) Neurological Disease (4)

By Targets:

Adrenergic Receptor (2)

Antibiotic (4)

Apoptosis (3)

Arrestin (2)

Autophagy (5)

Bacterial (18)

Biochemical Assay Reagents (7)

CXCR (2)

Drug-Linker Conjugates for ADC (1)

EGFR (1)

Endogenous Metabolite (2)

Endothelin Receptor (2)

ERK (1)

Estrogen Receptor/ERR (1)

Fluorescent Dye (1)

Fungal (3)

GHSR (1)

Glucosidase (1)

HCV (1)

HIF/HIF Prolyl-Hydroxylase (3)

IFNAR (1)

Integrin (11)

Isotope-Labeled Compounds (4)

Ligands for E3 Ligase (5)

MMP (2)

NF-κB (1)

Nuclear Factor of activated T Cells (NFAT) (1)

Opioid Receptor (2)

Oxytocin Receptor (1)

Parasite (1)

PD-1/PD-L1 (1)

Phosphatase (1)

PI3K (1)

PROTAC Linkers (1)

Proteasome (1)

Raf (1)

Ras (1)

Reactive Oxygen Species (1)

Somatostatin Receptor (4)

STAT (1)

Topoisomerase (1)

Vasopressin Receptor (1)

VEGFR (1)

By Research Areas:

Cancer (43)

Cardiovascular Disease (5)

Endocrinology (3)

Infection (20)

Inflammation/Immunology (13)

Metabolic Disease (7)

Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

100

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W007466

Cyclohexane-1,3-dione	Biochemical Assay Reagents	Others
Cyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W092895

Cyclohexane-PEG1-Br

PROTAC Linkers Cancer

Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Cyclohexane-PEG1-Br	PROTAC Linkers	Cancer
Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W021265

Cyclohexane-1,2,3,4,5,6-hexaol Cyclohexane-1,2,3,4,5,6-hexol	Biochemical Assay Reagents	Others
Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.

HY-130755

Cyclohexanoyl coenzyme A CHCoA; Cyclohexanecarboxyl-CoA; Cyclohexanoyl CoA	Others	Others
Cyclohexanoyl coenzyme A is the active form of cyclohexane carboxylic acid (CHC) from anaerobic degradation in Rhodopseudomonas palustris .

HY-Y1051S

*(Chlorocarbonyl)cyclohexane-d11* Cyclohexanecarboxylic acid chloride-d₁₁; Cyclohexanoic acid chlorid-d11e; Cyclohexanoyl chloride-d₁₁; Cyclohexylcarbonyl chloride-d₁₁; Hexahydrobenzoyl chloride-d₁₁; NSC 85181-d₁₁	Isotope-Labeled Compounds	Others
(Chlorocarbonyl)cyclohexane-d₁₁ is the deuterium labeled (Chlorocarbonyl)cyclohexane[1].

HY-W007732BS

1,4-Cyclohexane-d10

Isotope-Labeled Compounds Others

1,4-Cyclohexane-d₁₀ is the deuterium labeled 1,4-Cyclohexane[1].
HY-W007517S

(Bromomethyl)cyclohexane-d11

Isotope-Labeled Compounds Others

(Bromomethyl)cyclohexane-d₁₁ is the deuterium labeled (Bromomethyl)cyclohexane[1].
HY-W010514

trans-Cyclohexane-1,2-diol

Endogenous Metabolite Metabolic Disease

trans-Cyclohexane-1,2-diol is an endogenous metabolite.

*1,4-Cyclohexane-d10*	Isotope-Labeled Compounds	Others
1,4-Cyclohexane-d₁₀ is the deuterium labeled 1,4-Cyclohexane[1].

*(Bromomethyl)cyclohexane-d11*	Isotope-Labeled Compounds	Others
(Bromomethyl)cyclohexane-d₁₁ is the deuterium labeled (Bromomethyl)cyclohexane[1].

*trans-Cyclohexane-1,2-diol*	Endogenous Metabolite	Metabolic Disease
trans-Cyclohexane-1,2-diol is an endogenous metabolite.

HY-153067

*Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a coupling compound that can be used for the synthesis of ADC. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan synthesized ADC shows good antitumor activity in vitro and in vivo .

HY-163225

*(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc*	Ligands for E3 Ligase Autophagy	Cancer
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-163221

*(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc*	Ligands for E3 Ligase Autophagy	Cancer
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-163229

*(1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc*	Ligands for E3 Ligase Autophagy	Cancer
(1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-W403633

Hexahydrohippuric acid	Bacterial	Infection
Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity .

HY-163226

*(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc*	Ligands for E3 Ligase Autophagy	Cancer
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-163227

*(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc*	Ligands for E3 Ligase Autophagy	Cancer
(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-W013326S

Bisphenol Z-d6

Isotope-Labeled Compounds Others

Bisphenol Z-d₆is the deuterium labeled4,4'-(Cyclohexane-1,1-diyl)diphenol(HY-W013326) .
HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Phosphatase Others

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.
HY-W142997

Decylcyclohexane

N-DecylCyclohexane
Others Others

Decylcyclohexane (N-Decylcyclohexane) is a chemical composition that can be isolated from Spermadictyon suaveolens leaves .

Bisphenol Z-d6	Isotope-Labeled Compounds	Others
Bisphenol Z-d₆is the deuterium labeled4,4'-(Cyclohexane-1,1-diyl)diphenol(HY-W013326) .

AMPPD Lumi-Phos Plus; Lumigen PPD; PPD	Phosphatase	Others
AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

Decylcyclohexane N-DecylCyclohexane	Others	Others
Decylcyclohexane (N-Decylcyclohexane) is a chemical composition that can be isolated from Spermadictyon suaveolens leaves .

HY-19204

Zinc phthalocyanine ZnPc	Fluorescent Dye	Cancer
Zinc phthalocyanine is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT) . Zinc phthalocyanine can be used to photooxidise cyclohexane .

HY-N2383

Validamine (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)Cyclohexane-1,2,3-triol	Glucosidase	Metabolic Disease
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC₅₀ value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme .

HY-P0031

Cyclo(RADfK) 1 Publications Verification	Integrin	Others
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	NF-κB Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P0023

Cyclo(-RGDfK) Maximum Cited Publications 10 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-P0231

AZP-531

2 Publications Verification

GHSR Metabolic Disease Endocrinology

AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

AZP-531 2 Publications Verification	GHSR	Metabolic Disease Endocrinology
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

HY-P1934

Cyclo(Phe-Pro) 4 Publications Verification Cyclo(phenylalanylprolyl); A-64863	HCV	Infection
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)), a Vibrio vulnificus quorum-sensing molecule, inhibits retinoic acid-inducible gene-I (RIG-I) polyubiquitination, through its specific interaction with RIG-I, to blunt IRF-3 activation and type-I IFN production. Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) enhances susceptibility to hepatitis C virus (HCV), as well as Sendai and influenza viruses .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P0023A

Cyclo(-RGDfK) TFA Maximum Cited Publications 10 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-126810

NP213	Fungal	Infection
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .

HY-107245

Segetalin B

1 Publications Verification

Estrogen Receptor/ERR Metabolic Disease

Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity .

Segetalin B 1 Publications Verification	Estrogen Receptor/ERR	Metabolic Disease
Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P2300

Cyclo(Arg-Gly-Asp-D-Phe-Cys) Cyclo(RGDfC)	Integrin	Cancer
Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .

HY-P1938

Cyclo(L-Pro-L-Val)	Bacterial	Infection
Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide .

HY-P5033

Cyclo(Gly-His)	Bacterial	Cancer
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC₅₀ values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .

HY-P5314

OK2	EGFR STAT	Others
OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research .

HY-P1935

Cyclo(Ala-Pro)

Biochemical Assay Reagents Cancer

Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

Cyclo(Ala-Pro)	Biochemical Assay Reagents	Cancer
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P5038

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) c(GRGDSP)	Integrin	Cancer
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells .

HY-P5698

Cyclopetide 1

Bacterial Infection

Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .
HY-P5699

Cyclopetide 2

Bacterial Infection

Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

Cyclopetide 1	Bacterial	Infection
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

Cyclopetide 2	Bacterial	Infection
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P10052

CBO-P11	VEGFR	Cancer
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .

HY-P10222

Cyclo(CRLLIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 14.5 and 10.2 μM, respectively .

HY-P10223

Cyclo(CRVIIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CRVIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 65 and 123 μM, respectively .

HY-P10221

Cyclo(CKLIIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CKLIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 2.6 and 2.2 μM, respectively .

HY-P4820A

*SYNV-cyclo(CGGYF) TFA*	Bacterial	Inflammation/Immunology
SYNV-cyclo(CGGYF) TFA is a Staphylococcus hominis (S. hominis) C5 autoinducing peptide. SYNV-cyclo(CGGYF) TFA inhibits S. aureus activity. SYNV-cyclo(CGGYF) TFA has the potential for the research of S. aureus-mediated epithelial damage and inflammation .

HY-P4820

*SYNV-cyclo(CGGYF)*	Bacterial	Inflammation/Immunology
SYNV-cyclo(CGGYF) is a Staphylococcus hominis (S. hominis) C5 autoinducing peptide. SYNV-cyclo(CGGYF) inhibits S. aureus activity. SYNV-cyclo(CGGYF) has the potential for the research of S. aureus-mediated epithelial damage and inflammation .

HY-P3227

Cyclo(Ala-Arg-Gly-Asp-Mamb) XJ735	Integrin	Inflammation/Immunology
Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research .

HY-P5712

Gramicidin S Gramicidin soviet	Antibiotic Bacterial	Infection
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase .

HY-P1201

Cyclosomatostatin	Somatostatin Receptor	Cancer
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells .

HY-P1201A

Cyclosomatostatin TFA	Somatostatin Receptor	Cancer
Cyclosomatostatin TFA is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin TFA can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells .

HY-149205

CXJ-2	PI3K ERK	Inflammation/Immunology
CXJ-2 is a cyclic peptide, and exhibits moderate affinity toward elastin derived peptides (EDPs). CXJ-2 exhibits potent activities to inhibit the PI3K/ERK pathway and decrease hepatic stellate cell proliferation and migration. CXJ-2 possesses potent antifibrotic efficacy .

HY-P5840

Cyclo(RGDyC)	Biochemical Assay Reagents	Cancer
Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010514

*trans-Cyclohexane-1,2-diol*	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
trans-Cyclohexane-1,2-diol is an endogenous metabolite.

HY-107245

Segetalin B 1 Publications Verification	Vaccaria segetalis (Neck.) Garcke Classification of Application Fields Cyclopeptides Source classification Metabolic Disease Plants Disease Research Fields Caryophyllaceae	Estrogen Receptor/ERR
Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity .

HY-W142997

Decylcyclohexane N-DecylCyclohexane	Structural Classification Natural Products Source classification Rubiaceae Plants Spermadictyon suaveolens Roxb.	Others
Decylcyclohexane (N-Decylcyclohexane) is a chemical composition that can be isolated from Spermadictyon suaveolens leaves .

HY-N2383

Validamine (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)Cyclohexane-1,2,3-triol	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Glucosidase
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC₅₀ value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme .

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal IFNAR Reactive Oxygen Species
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P1938

Cyclo(L-Pro-L-Val)	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide .

HY-P1935

Cyclo(Ala-Pro)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Biochemical Assay Reagents
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P5698

Cyclopetide 1	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-P5699

Cyclopetide 2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P1680

Astin C Asterin	Structural Classification Natural Products Source classification Plants Compositae Erythrina latissima E. Mey.	Others
Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties .

HY-P2040

Nodularin	Structural Classification other families Cyclopeptides Ketones, Aldehydes, Acids Source classification Marine natural products Plants	Others
Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-W019721

Cyclosporin D	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Nuclear Factor of activated T Cells (NFAT)
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

HY-P2005

Malformin C	Structural Classification Natural Products Microorganisms Source classification	Others
Malformin C is an algicidal peptide can be isolated from Aspergillus and exhibits dose-dependent algicidal activity. Malformin C induces a significant increase in ROS levels in algal cells, resulting in impaired SOD activity and high production of MDA content .

HY-P5957

Omphalotin A

Structural Classification Microorganisms Cyclopeptides Source classification

Parasite

Omphalotin A is a cyclic peptide, and shows nematicidal activity .

Cat. No.	Product Name	Chemical Structure

HY-W013326S

Bisphenol Z-d6

Bisphenol Z-d₆is the deuterium labeled4,4'-(Cyclohexane-1,1-diyl)diphenol(HY-W013326) .
HY-Y1051S

(Chlorocarbonyl)cyclohexane-d11

(Chlorocarbonyl)cyclohexane-d₁₁ is the deuterium labeled (Chlorocarbonyl)cyclohexane[1].
HY-W007732BS

1,4-Cyclohexane-d10

1,4-Cyclohexane-d₁₀ is the deuterium labeled 1,4-Cyclohexane[1].
HY-W007517S

(Bromomethyl)cyclohexane-d11

(Bromomethyl)cyclohexane-d₁₁ is the deuterium labeled (Bromomethyl)cyclohexane[1].

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