Cyclorasin 9A5
Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC50 of 120 nM.
For research use only. We do not sell to patients.
- CAS No.: 1782098-79-6
- Formula: C75H108FN25O13
- Molecular Weight:1586.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 120 nM (Ras-Raf protein interaction)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H1299 | EC50 |
3 μM
Compound: Cyclorasin 9A5
|
Induction of apoptosis in human NCI-H1299 cells by MTT assay
Induction of apoptosis in human NCI-H1299 cells by MTT assay
|
[PMID: 34415745] |
Chemical Information
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CAS No. 1782098-79-6
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Molecular Weight 1586.82
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Formula C75H108FN25O13
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Sequence
Cyclo({d-Ala}-Arg-Arg-Arg-{d-Nal}-Arg-{4F-Phe}-{d-Nle}-Gln-Trp-Thr)
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Sequence Shortening
Cyclo({d-Ala}-RRR-{d-Nal}-R-{4F-Phe}-{d-Nle}-QWT)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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