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  6. Astin C

Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Astin C Chemical Structure

Astin C Chemical Structure

CAS No. : 148057-23-2

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1 mg USD 175 In-stock
5 mg USD 350 In-stock
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Description

Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties[1].

Molecular Weight

570.47

Formula

C25H33Cl2N5O6
CAS No.
Appearance

Solid

Color

Off-white to yellow

Sequence

Cyclo({Abu}-Pro-{Abu}-Ser-{Oaa})
Sequence Shortening

Cyclo({Abu}-P-{Abu}-S-{Oaa})
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (175.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7529 mL 8.7647 mL 17.5294 mL
5 mM 0.3506 mL 1.7529 mL 3.5059 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.77%

COA (259 KB) RP-HPLC (261 KB) MS (71 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7529 mL 8.7647 mL 17.5294 mL 43.8235 mL
5 mM 0.3506 mL 1.7529 mL 3.5059 mL 8.7647 mL
10 mM 0.1753 mL 0.8765 mL 1.7529 mL 4.3824 mL
15 mM 0.1169 mL 0.5843 mL 1.1686 mL 2.9216 mL
20 mM 0.0876 mL 0.4382 mL 0.8765 mL 2.1912 mL
25 mM 0.0701 mL 0.3506 mL 0.7012 mL 1.7529 mL
30 mM 0.0584 mL 0.2922 mL 0.5843 mL 1.4608 mL
40 mM 0.0438 mL 0.2191 mL 0.4382 mL 1.0956 mL
50 mM 0.0351 mL 0.1753 mL 0.3506 mL 0.8765 mL
60 mM 0.0292 mL 0.1461 mL 0.2922 mL 0.7304 mL
80 mM 0.0219 mL 0.1096 mL 0.2191 mL 0.5478 mL
100 mM 0.0175 mL 0.0876 mL 0.1753 mL 0.4382 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Astin C148057-23-2AsterinOthersnonribosomal peptidecyclic pentapeptideanticancer and anti-inflammatory propertiesInhibitorinhibitorinhibit

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