2. Cytoskeleton
  3. Integrin
  4. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)  (Synonyms: c(GRGDSP))

製品番号: HY-P5038 純度: 98.11%
COA 取扱説明書 Technical Support

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells.

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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) 構造式

CAS 番号 : 135432-37-0

容量 価格（税別） 在庫状況 数量
1 mg $115 在庫あり
5 mg $285 在庫あり
10 mg $425 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) 関連抗体

Top Publications Citing Use of Products

Integrin アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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製品説明

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells[1].

分子量

569.57

分子式

C22H35N9O9
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
Sequence Shortening

Cyclo(GRGDSP)
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (175.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7557 mL 8.7786 mL 17.5571 mL
5 mM 0.3511 mL 1.7557 mL 3.5114 mL
10 mM 0.1756 mL 0.8779 mL 1.7557 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7557 mL 8.7786 mL 17.5571 mL 43.8928 mL
5 mM 0.3511 mL 1.7557 mL 3.5114 mL 8.7786 mL
10 mM 0.1756 mL 0.8779 mL 1.7557 mL 4.3893 mL
15 mM 0.1170 mL 0.5852 mL 1.1705 mL 2.9262 mL
20 mM 0.0878 mL 0.4389 mL 0.8779 mL 2.1946 mL
25 mM 0.0702 mL 0.3511 mL 0.7023 mL 1.7557 mL
30 mM 0.0585 mL 0.2926 mL 0.5852 mL 1.4631 mL
40 mM 0.0439 mL 0.2195 mL 0.4389 mL 1.0973 mL
50 mM 0.0351 mL 0.1756 mL 0.3511 mL 0.8779 mL
60 mM 0.0293 mL 0.1463 mL 0.2926 mL 0.7315 mL
80 mM 0.0219 mL 0.1097 mL 0.2195 mL 0.5487 mL
100 mM 0.0176 mL 0.0878 mL 0.1756 mL 0.4389 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)135432-37-0c(GRGDSP)Integrininhibitory peptideInhibitorinhibitorinhibit

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製品名:
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
製品番号:
HY-P5038
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