Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
Based on 1 Customer Validation
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells.
For research use only. We do not sell to patients.
- Purity : 98.11%
- CAS No.: 135432-37-0
- Formula: C22H35N9O9
- Molecular Weight:569.57
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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CAS No. 135432-37-0
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Appearance Solid
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Molecular Weight 569.57
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Formula C22H35N9O9
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Color White to off-white
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Synonyms
c(GRGDSP)
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Sequence
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
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Sequence Shortening
Cyclo(GRGDSP)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : ≥ 100 mg/mL (175.57 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.7557 mL | 8.7786 mL | 17.5571 mL | 43.8928 mL |
| 5 mM | 0.3511 mL | 1.7557 mL | 3.5114 mL | 8.7786 mL | |
| 10 mM | 0.1756 mL | 0.8779 mL | 1.7557 mL | 4.3893 mL | |
| 15 mM | 0.1170 mL | 0.5852 mL | 1.1705 mL | 2.9262 mL | |
| 20 mM | 0.0878 mL | 0.4389 mL | 0.8779 mL | 2.1946 mL | |
| 25 mM | 0.0702 mL | 0.3511 mL | 0.7023 mL | 1.7557 mL | |
| 30 mM | 0.0585 mL | 0.2926 mL | 0.5852 mL | 1.4631 mL | |
| 40 mM | 0.0439 mL | 0.2195 mL | 0.4389 mL | 1.0973 mL | |
| 50 mM | 0.0351 mL | 0.1756 mL | 0.3511 mL | 0.8779 mL | |
| 60 mM | 0.0293 mL | 0.1463 mL | 0.2926 mL | 0.7315 mL | |
| 80 mM | 0.0219 mL | 0.1097 mL | 0.2195 mL | 0.5487 mL | |
| 100 mM | 0.0176 mL | 0.0878 mL | 0.1756 mL | 0.4389 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.