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  3. Cyclo(RGDyC)

Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer.

For research use only. We do not sell to patients.

Cyclo(RGDyC) Chemical Structure

Cyclo(RGDyC) Chemical Structure

CAS No. : 1206475-79-7

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1 mg USD 70 In-stock
5 mg USD 180 In-stock
10 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Cyclo(RGDyC):

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Description

Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer[1][2].

Molecular Weight

594.64

Formula

C24H34N8O8S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

cyclo(Arg-Gly-Asp-{d-Tyr}-Cys)

Sequence Shortening

cyclo(RGD-{d-Tyr}C)

SMILES

O=C([C@@H](NC(CNC([C@@H](NC([C@@H](NC1=O)CS)=O)CCCNC(N)=N)=O)=O)CC(O)=O)N[C@@H]1CC2=CC=C(C=C2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (140.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6817 mL 8.4084 mL 16.8169 mL
5 mM 0.3363 mL 1.6817 mL 3.3634 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6817 mL 8.4084 mL 16.8169 mL 42.0422 mL
5 mM 0.3363 mL 1.6817 mL 3.3634 mL 8.4084 mL
10 mM 0.1682 mL 0.8408 mL 1.6817 mL 4.2042 mL
15 mM 0.1121 mL 0.5606 mL 1.1211 mL 2.8028 mL
20 mM 0.0841 mL 0.4204 mL 0.8408 mL 2.1021 mL
25 mM 0.0673 mL 0.3363 mL 0.6727 mL 1.6817 mL
30 mM 0.0561 mL 0.2803 mL 0.5606 mL 1.4014 mL
40 mM 0.0420 mL 0.2102 mL 0.4204 mL 1.0511 mL
50 mM 0.0336 mL 0.1682 mL 0.3363 mL 0.8408 mL
60 mM 0.0280 mL 0.1401 mL 0.2803 mL 0.7007 mL
80 mM 0.0210 mL 0.1051 mL 0.2102 mL 0.5255 mL
100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.4204 mL
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Cyclo(RGDyC) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cyclo(RGDyC)
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