Cyclo(RGDyC)
Based on 1 Customer Validation
Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer.
For research use only. We do not sell to patients.
- Purity: 98.29%
- CAS No.: 1206475-79-7
- Formula: C24H34N8O8S
- Molecular Weight:594.64
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 1206475-79-7
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Appearance Solid
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Molecular Weight 594.64
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Formula C24H34N8O8S
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Color White to off-white
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Sequence
cyclo(Arg-Gly-Asp-{d-Tyr}-Cys)
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Sequence Shortening
cyclo(RGD-{d-Tyr}C)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 83.33 mg/mL (140.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Lu Y, et al. Aqueous synthesized near-infrared-emitting quantum dots for RGD-based in vivo active tumour targeting. Nanotechnology. 2013 Apr 5;24(13):135101. [Content Brief]
[2]. Tang M, et al. Photostable and Biocompatible Fluorescent Silicon Nanoparticles-Based Theranostic Probes for Simultaneous Imaging and Treatment of Ocular Neovascularization. Anal Chem. 2018 Jul 3;90(13):8188-8195. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6817 mL | 8.4084 mL | 16.8169 mL | 42.0422 mL |
| 5 mM | 0.3363 mL | 1.6817 mL | 3.3634 mL | 8.4084 mL | |
| 10 mM | 0.1682 mL | 0.8408 mL | 1.6817 mL | 4.2042 mL | |
| 15 mM | 0.1121 mL | 0.5606 mL | 1.1211 mL | 2.8028 mL | |
| 20 mM | 0.0841 mL | 0.4204 mL | 0.8408 mL | 2.1021 mL | |
| 25 mM | 0.0673 mL | 0.3363 mL | 0.6727 mL | 1.6817 mL | |
| 30 mM | 0.0561 mL | 0.2803 mL | 0.5606 mL | 1.4014 mL | |
| 40 mM | 0.0420 mL | 0.2102 mL | 0.4204 mL | 1.0511 mL | |
| 50 mM | 0.0336 mL | 0.1682 mL | 0.3363 mL | 0.8408 mL | |
| 60 mM | 0.0280 mL | 0.1401 mL | 0.2803 mL | 0.7007 mL | |
| 80 mM | 0.0210 mL | 0.1051 mL | 0.2102 mL | 0.5255 mL | |
| 100 mM | 0.0168 mL | 0.0841 mL | 0.1682 mL | 0.4204 mL |