JLB2-110c
JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect.
For research use only. We do not sell to patients.
- CAS No.: 3032608-72-0
- Formula: C71H108N28O12
- Molecular Weight:1545.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 3032608-72-0
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Molecular Weight 1545.80
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Formula C71H108N28O12
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Sequence
Cyclo(Pro-His-{d-Phe}-Arg-Trp-{Dap}-{Lys(Ac-Arg-Arg-Arg)}-{d-Pro})
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Sequence Shortening
Cyclo(PH-{d-Phe}-RW-{Dap}-{Lys(Ac-RRR)}-{d-Pro})
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ericson MD, et al. Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS Pharmacol Transl Sci. 2024 Apr 2;7(4):1114-1125. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JLB2-110c Related Classifications
HY-P6176 Related Classifications
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