2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc 

Cat. No.: HY-163225
Handling Instructions Technical Support

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc 화학구조

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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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제품 설명

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

IC50 & Target

Cereblon

 

분자량

553.65

화학식

C29H39N5O6
SMILES

O=C1NC(CC[C@@H]1N2C(C3=C(C=CC(N4CCN(CC4)C[C@H]5CC[C@@H](CC5)NC(OC(C)(C)C)=O)=C3)C2=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-BocE3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisE3 ligase ligand-linker conjugatesPomalidomidePROTACInhibitorinhibitorinhibit

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상품명:
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc
Cat. No.:
HY-163225
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