2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc 

Art. -Nr.: HY-163225
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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Chemische Struktur

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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Beschreibung

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

IC50 & Target

Cereblon

 

Molekulargewicht

553.65

Formel

C29H39N5O6
SMILES

O=C1NC(CC[C@@H]1N2C(C3=C(C=CC(N4CCN(CC4)C[C@H]5CC[C@@H](CC5)NC(OC(C)(C)C)=O)=C3)C2=O)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Related Classifications

  • Molaritätsrechner

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

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Keywords:

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-BocE3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisE3 ligase ligand-linker conjugatesPomalidomidePROTACInhibitorinhibitorinhibit

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