Cyclo(Ala-Arg-Gly-Asp-Mamb)
Based on 1 Customer Validation
Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension research.
For research use only. We do not sell to patients.
- Purity : 99.70%
- CAS No.: 153381-95-4
- Formula: C23H32N8O7
- Molecular Weight:532.55
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
IC50 & Target
IC50: αVβ3 integrin[1]
Chemical Information
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CAS No. 153381-95-4
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Appearance Solid
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Molecular Weight 532.55
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Formula C23H32N8O7
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Color White to light yellow
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Synonyms
XJ735
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Sequence
Cyclo(Ala-Arg-Gly-Asp-{Oaa})
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Sequence Shortening
Cyclo(ARGD-{Oaa})
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (46.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8778 mL | 9.3888 mL | 18.7776 mL | 46.9440 mL |
| 5 mM | 0.3756 mL | 1.8778 mL | 3.7555 mL | 9.3888 mL | |
| 10 mM | 0.1878 mL | 0.9389 mL | 1.8778 mL | 4.6944 mL | |
| 15 mM | 0.1252 mL | 0.6259 mL | 1.2518 mL | 3.1296 mL | |
| 20 mM | 0.0939 mL | 0.4694 mL | 0.9389 mL | 2.3472 mL | |
| 25 mM | 0.0751 mL | 0.3756 mL | 0.7511 mL | 1.8778 mL | |
| 30 mM | 0.0626 mL | 0.3130 mL | 0.6259 mL | 1.5648 mL | |
| 40 mM | 0.0469 mL | 0.2347 mL | 0.4694 mL | 1.1736 mL |