Cyclo(CRVIIF)
Cyclo CRVIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains KD of 65 and 123 μM, respectively.
For research use only. We do not sell to patients.
- Formula: C35H57N9O6S
- Molecular Weight:731.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIF-1α 65 μM (Kd) |
HIF-2α 123 μM (Kd) |
Chemical Information
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Molecular Weight 731.95
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Formula C35H57N9O6S
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Sequence
Cyclo(Cys-Arg-Val-Ile-Ile-Phe)
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Sequence Shortening
Cyclo(CRVIIF)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)