2. Peptides
  3. E(c(RGDfK))2

E(c(RGDfK)) is an αvβ3 integrin-specific binding moiety with tumor targeting properties. Increased uptake of E(c(RGDfK)) in human ovarian cancer OVCAR-3 xenograft tumors may be useful in cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

E(c(RGDfK))2 Chemical Structure

E(c(RGDfK))2 Chemical Structure

CAS No. : 250612-47-6

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1 mg USD 120 In-stock
5 mg USD 300 In-stock
10 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

E(c(RGDfK))2 Related Antibodies

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Description

E(c(RGDfK)) is an αvβ3 integrin-specific binding moiety with tumor targeting properties. Increased uptake of E(c(RGDfK)) in human ovarian cancer OVCAR-3 xenograft tumors may be useful in cancer research[1].

Molecular Weight

1318.44

Formula

C59H87N19O16
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Glu[cyclo(Arg-Gly-Asp-{d-Phe}-Lys)]-cyclo(Arg-Gly-Asp-{d-Phe}-Lys)
Sequence Shortening

E[cyclo(RGD-{d-Phe}-K)]-cyclo(RGD-{d-Phe}-K)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (75.85 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7585 mL 3.7924 mL 7.5847 mL
5 mM 0.1517 mL 0.7585 mL 1.5169 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7585 mL 3.7924 mL 7.5847 mL 18.9618 mL
5 mM 0.1517 mL 0.7585 mL 1.5169 mL 3.7924 mL
10 mM 0.0758 mL 0.3792 mL 0.7585 mL 1.8962 mL
15 mM 0.0506 mL 0.2528 mL 0.5056 mL 1.2641 mL
20 mM 0.0379 mL 0.1896 mL 0.3792 mL 0.9481 mL
25 mM 0.0303 mL 0.1517 mL 0.3034 mL 0.7585 mL
30 mM 0.0253 mL 0.1264 mL 0.2528 mL 0.6321 mL
40 mM 0.0190 mL 0.0948 mL 0.1896 mL 0.4740 mL
50 mM 0.0152 mL 0.0758 mL 0.1517 mL 0.3792 mL
60 mM 0.0126 mL 0.0632 mL 0.1264 mL 0.3160 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E(c(RGDfK))2250612-47-6OthersPeptidesInhibitorinhibitorinhibit

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