2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. WL12

WL12 

Cat. No.: HY-P3440 Purity: 98.49%
COA Handling Instructions

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

WL12 Chemical Structure

WL12 Chemical Structure

Size Price Stock Quantity
1 mg USD 350 In-stock
5 mg USD 950 In-stock
10 mg USD 1550 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

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Description

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression[1].

IC50 & Target

PD-L1[1]
Molecular Weight

1882.19

Appearance

Solid

Formula

C91H128N22O20S
Sequence Shortening

Cyclo(Ac-Y-{A(Me)}-NPHL-{Hyp}-WS{W(Me)}-{Nle(Me)}-{Nle(Me)}-{Orn}-C)G-NH2 (Thioether bridge: Cys14-Ac-Tyr)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (26.56 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5313 mL 2.6565 mL 5.3130 mL
5 mM 0.1063 mL 0.5313 mL 1.0626 mL
10 mM 0.0531 mL 0.2656 mL 0.5313 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

WL12WL 12WL-12PD-1/PD-L1PD-1/Programmed death-ligand 1binding peptidetumorInhibitorinhibitorinhibit

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