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Results for "

binders

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Antibiotic (3) Apoptosis (6) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (13) c-Myc (1) COX (1) DNA Alkylator/Crosslinker (6) DNA/RNA Synthesis (6) Drug-Linker Conjugates for ADC (2) Endogenous Metabolite (2) Enterovirus (3) Epigenetic Reader Domain (2) FAK (1) G-quadruplex (1) HCV (1) Histone Acetyltransferase (1) Histone Methyltransferase (2) HIV (1) Influenza Virus (1) JAK (1) Keap1-Nrf2 (1) Ligands for E3 Ligase (5) Ligands for Target Protein for PROTAC (3) mAChR (2) MDM-2/p53 (1) MicroRNA (1) Microtubule/Tubulin (1) Molecular Glues (1) Nuclear Hormone Receptor 4A/NR4A (2) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (1) Paraptosis (1) Parasite (2) Phosphodiesterase (PDE) (2) Potassium Channel (1) PPAR (1) PROTACs (8) PSMA (3) RAD51 (1) RAR/RXR (1) Reactive Oxygen Species (1) RIP kinase (1) Sodium Channel (1) Tau Protein (1)
By Research Areas:	Cancer (40) Infection (9) Inflammation/Immunology (8) Metabolic Disease (6) Neurological Disease (4)

By Targets:

Androgen Receptor (1)

Antibiotic (3)

Apoptosis (6)

Autophagy (1)

Bacterial (1)

Biochemical Assay Reagents (13)

c-Myc (1)

COX (1)

DNA Alkylator/Crosslinker (6)

DNA/RNA Synthesis (6)

Drug-Linker Conjugates for ADC (2)

Endogenous Metabolite (2)

Enterovirus (3)

Epigenetic Reader Domain (2)

FAK (1)

G-quadruplex (1)

HCV (1)

Histone Acetyltransferase (1)

Histone Methyltransferase (2)

HIV (1)

Influenza Virus (1)

JAK (1)

Keap1-Nrf2 (1)

Ligands for E3 Ligase (5)

Ligands for Target Protein for PROTAC (3)

mAChR (2)

MDM-2/p53 (1)

MicroRNA (1)

Microtubule/Tubulin (1)

Molecular Glues (1)

Nuclear Hormone Receptor 4A/NR4A (2)

Orexin Receptor (OX Receptor) (1)

Orthopoxvirus (1)

Paraptosis (1)

Parasite (2)

Phosphodiesterase (PDE) (2)

Potassium Channel (1)

PPAR (1)

PROTACs (8)

PSMA (3)

RAD51 (1)

RAR/RXR (1)

Reactive Oxygen Species (1)

RIP kinase (1)

Sodium Channel (1)

Tau Protein (1)

By Research Areas:

Cancer (40)

Infection (9)

Inflammation/Immunology (8)

Metabolic Disease (6)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-156215

NCI-B16

HCV Infection

NCI-B16 is a small molecule RNA binder and inhibits HCV viral replication .
HY-141536

PSMA-ALB-56

Drug-Linker Conjugates for ADC Cancer

PSMA-ALB-56 is a PSMA-targeting radioligand designed by combining the glutamate-urea PSMA-binding entity and an albumin binder .

NCI-B16	HCV	Infection
NCI-B16 is a small molecule RNA binder and inhibits HCV viral replication .

PSMA-ALB-56	Drug-Linker Conjugates for ADC	Cancer
PSMA-ALB-56 is a PSMA-targeting radioligand designed by combining the glutamate-urea PSMA-binding entity and an albumin binder .

HY-156970

*Phosphatase Binder-1*	Others	Cancer
Phosphatase Binder-1 (comppund i-196) provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Phosphatase Binder-1 plays an important role in cancer .

HY-152243

*YEATS4 binder-1*	Others	Others
YEATS4 binder-1(4e) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a K_i value of 37 nM .

HY-152242

YEATS4-IN-1	Others	Others
YEATS4-IN-1 (Compound 4d) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a K_i value of 33 nM .

HY-112939

Colestilan MCI-196; Colestimide	Others	Metabolic Disease
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research .

HY-153910

AGPS-IN-1	Others	Cancer
AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells .

HY-N1428C

Ferric citrate 1 Publications Verification Iron(III) citrate; Zerenex	Reactive Oxygen Species Antibiotic	Metabolic Disease
Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research .

HY-B2225C

Starch (pregelatinized) Edible corn starch (pregelatinized)	Biochemical Assay Reagents	Others
Starch pregelatinized can be used as an excipient, such as Glidants, diluents, disintegrants, binders, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-112058

Distamycin A NSC-82150	Antibiotic Apoptosis	Infection
Distamycin A (NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis .

HY-148433

*SpdSyn binder-1*	Parasite	Infection Inflammation/Immunology
SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria .

HY-145287

S-MGB-234	DNA/RNA Synthesis Parasite	Infection
S-MGB-234 is a minor groove binder of Animal African Trypanosomiasis (AAT). S-MGB-234 displays excellent in vitro activities against the principal causative organisms of AAT; Trypanosoma congolense, and Trypanosoma vivax. S-MGB-234 does not show cross-resistance with the current diamidine agents and are not internalized via the transporters used by diamidines .

HY-W595340

*E3 ubiquitin ligase binder-1*	Ligands for E3 Ligase	Cancer
E3 ubiquitin ligase binder-1 (compound 11) is a potent E3 ubiquitin ligase binder. E3 ubiquitin ligase binder-1 is a ligand for E3 Ligase .

HY-116785

BRD32048	DNA/RNA Synthesis	Cancer
BRD32048 is a direct binder of ETV1 with a K_D of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen .

HY-146186

*JAK2 JH2 binder-1*	JAK	Cancer
JAK2 JH2 binder-1 (compound 11) is a potent and selective JAK2 JH2 binder, with a K_d of 37.1 nM. JAK2 JH2 binder-1 has the potential for various myeloproliferative neoplasms research .

HY-163289

*TSLP binder-1*	Others	Inflammation/Immunology
TSLP binder-1 (compound 46) is a bicyclic peptide, which binds to thymic stromal lymphopoietin (TSLP) at the site used by IL-7Rα subunit, shows high affinity for TSLP, with K_D of 13 nM. TSLP binder-1 reveals good stability in rat plasma and rat lung S9 fraction .

HY-W250721D

Carbomer Carboxy polymethylene	Biochemical Assay Reagents	Others
Carbomer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W250721E

Carbomer copolymer Carboxy polymethylene (copolymer)	Biochemical Assay Reagents	Others
Carbomer copolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W250721F

Carbomer homopolymer Carboxy polymethylene (homopolymer)	Biochemical Assay Reagents	Others
Carbomer homopolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W250721G

Carbomer interpolymer Carboxy polymethylene (interpolymer)	Biochemical Assay Reagents	Others
Carbomer interpolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-133821

N-Methylmesoporphyrin IX	G-quadruplex	Neurological Disease
N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .

HY-149934

*DCAF1 binder* 1**	Ligands for E3 Ligase	Cancer
DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD) .

HY-B0327

Irsogladine 1 Publications Verification Dicloguamine	mAChR Phosphodiesterase (PDE)	Inflammation/Immunology
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.

HY-B0327A

Irsogladine maleate

Dicloguamine maleate; MN1695
mAChR Phosphodiesterase (PDE) Inflammation/Immunology

Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.
HY-156499

RNF114 ligand 1

Others Others

RNF114 ligand 1 is a E3 Ubiquitin ligase binder .
HY-139645

MtDTBS-IN-1

Others Infection

MtDTBS-IN-1 is a particularly potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.
HY-139620

MS83

PROTACs Cancer

MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder.
HY-156743

DCAF1 binder 2

Others Others

DCAF1 binder 2, a ligands for E3 Ligase, involves in BRD9, kinase and selective BTK degration.
HY-144980

E3 ligase Ligand 21

Ligands for E3 Ligase Cancer

E3 ligase Ligand 21 (compound 2) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .

Irsogladine maleate Dicloguamine maleate; MN1695	mAChR Phosphodiesterase (PDE)	Inflammation/Immunology
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.

RNF114 ligand 1	Others	Others
RNF114 ligand 1 is a E3 Ubiquitin ligase binder .

MtDTBS-IN-1	Others	Infection
MtDTBS-IN-1 is a particularly potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.

MS83	PROTACs	Cancer
MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder.

*DCAF1 binder* 2**	Others	Others
DCAF1 binder 2, a ligands for E3 Ligase, involves in BRD9, kinase and selective BTK degration.

E3 ligase Ligand 21	Ligands for E3 Ligase	Cancer
E3 ligase Ligand 21 (compound 2) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .

HY-144983

E3 ligase Ligand 22	Ligands for E3 Ligase	Cancer
E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .

HY-144985

E3 ligase Ligand 23	Ligands for E3 Ligase	Cancer
E3 ligase Ligand 23 (compound 17-6) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway .

HY-146382

WRNA10

HIV Inflammation/Immunology

WRNA10 is a potent HIV-1 TAR RNA binder with an IC₅₀ of 10 µM and an CC₅₀ of 40 µM .

WRNA10	HIV	Inflammation/Immunology
WRNA10 is a potent HIV-1 TAR RNA binder with an IC₅₀ of 10 µM and an CC₅₀ of 40 µM .

HY-112961

Patiromer	Potassium Channel	Others
Patiromer is an orally active and potent hyperkalemia inhibitor and a nonabsorbed potassium binder. Patiromer polymer is bound with calcium which is released in the colon in exchange for binding potassium .

HY-123885

NSC243928 mesylate

Others Cancer

NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity .

NSC243928 mesylate	Others	Cancer
NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity .

HY-139325

NHS-Modified MMAF	Drug-Linker Conjugates for ADC	Others
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .

HY-149306

MS78	Histone Acetyltransferase MDM-2/p53	Cancer
MS78 is an acetylation targeting chimera (AceTAC) that acetylates the p53 tumor suppressor protein. MS78 recruits histone acetyltransferase p300/CBP to acetylate the p53Y220C mutant. MS78 upregulates TRAIL apoptotic genes and downregulates DNA damage response pathways. MS78 contains a CBP/p300 binder, a p53Y220C binder and a linker .

HY-144333

DNA crosslinker 1 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 1 (dihydrochloride) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.1 °C. DNA crosslinker 1 (dihydrochloride) can be used for researching anticancer .

HY-Y0319C1

Calcium acetate, United States Pharmacopeia (USP) Reference Standard Calcium acetate (Pharmaceutical primary standard, USP)	Biochemical Assay Reagents	Metabolic Disease
Calcium acetate, United States Pharmacopeia (USP) Reference Standard (Calcium acetate (Pharmaceutical primary standard, USP)), a phosphate binder that can reduce phosphorus content, United States Pharmacopeia (USP) reference standard .

HY-111870

PROTAC RIPK degrader-6	PROTACs RIP kinase	Cancer
PROTAC RIPK degrader-6 (example 1) is a Cereblon-based PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder .

HY-144336

DNA crosslinker 3 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 3 (dihydrochloride) (compound 1) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.4 °C. DNA crosslinker 3 (dihydrochloride) can be used for researching anticancer .

HY-158125

*PSMA binder-2*	PSMA	Cancer
PSMA binder-2 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with ¹¹¹In, it can be used as DOTA chelating agent and imaging agent. Or labeled with ²²⁵Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .

HY-16293

Lurbinectedin 2 Publications Verification PM01183; LY-01017	DNA Alkylator/Crosslinker DNA/RNA Synthesis	Cancer
Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC₅₀ values of 1.25 and 1.16 nM, respectively.

HY-139620A

MS83 epimer 1

PROTACs Others

MS83 epimer 1 is the epimer of MS83 (HY-139620). MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder .

MS83 epimer 1	PROTACs	Others
MS83 epimer 1 is the epimer of MS83 (HY-139620). MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder .

HY-W039943

Acetyl-cyclosporin A aldehyde	Molecular Glues	Cancer
Acetyl-cyclosporin A aldehyde is an acetylated Cyclosporin A (HY-B0579) derivative with a reducing aldehyde group. Cyclosporin A is a potent calmodulin inhibitor and cyclophilin binder that can target the nuclear translocation of NF-AT and cause mitochondrial damage.

HY-N8773

3,5,7-Trihydroxychromone	Others	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-N6800A

Netropsin dihydrochloride	DNA/RNA Synthesis Bacterial Influenza Virus Antibiotic Orthopoxvirus	Infection Inflammation/Immunology
Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei . Netropsin dihydrochloride exhibits antiviral activity against the vaccinia virus .

HY-151476

GID4 Ligand 2	Ligands for Target Protein for PROTAC	Cancer
GID4 Ligand 2 (compound 67) is a selective GID4 binder (IC₅₀=18.9 μM; K_d=17 μM). GID4 Ligand 2 can be used for the synthesis of PROTACs .

HY-151479

GID4 Ligand 3	Others	Cancer
GID4 Ligand 3 (compound 16) is a binder of GID4 with an K_d value of 110 μM in vitro and an IC₅₀ value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau .

HY-106254

Vapendavir BTA798	Enterovirus	Infection
Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC₅₀ values of 0.5-1.4 μM in different EV71 strains .

HY-16293S

Lurbinectedin-d3 PM01183-d₃; LY-01017-d₃	DNA Alkylator/Crosslinker DNA/RNA Synthesis	Cancer
Lurbinectedin-d₃ is deuterium labeled Lurbinectedin. Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively[1].

Cat. No.	Product Name

HY-L129

Target Protein Ligand Library

39 compounds

Proteolysis-targeting chimera (PROTAC) has been developed to be a useful technology for targeted protein degradation. PROTACs consist of a ligand for E3 ligase (E3 ligase binder), a linker and a ligand (mostly small-molecule inhibitor) for protein of interest（target binder）. Upon binding to the target protein, the PROTACs can recruit E3 for target protein ubiquitination, which is subjected to proteasome-mediated degradation. Therefore, PROTACs execute their functions by degrading the target proteins rather than inhibiting them, which has a great superiority in overcoming resistance caused by target mutation or overexpression. To date, PROTAC technology has been applied to a variety of targets, including AR, ER, BTK, BET, and BCR-ABL to overcome resistance.

MCE carefully prepared a unique collection of 39 ligands for target proteins, which have been reported to be used in PROTAC design. MCE Target Protein Ligand Library is a useful tool for PROTAC development.

HY-L128

E3 Ligase Ligand Library

88 compounds

Although there are more than 600 E3 ubiquitin ligases, only several with small molecule ligands have been used for designing PROTACs, including Skp1-Cullin-F box complex containing Hrt1 (SCF), Von Hippel-Lindau tumor suppressor (VHL), Cereblon (CRBN), inhibitor of apoptosis proteins (IAPs), and mouse double minute 2 homolog (MDM2).

MCE carefully prepared a unique collection of 88 ligands for E3 ligase, which have been reported to be used in PROTAC design. MCE E3 ligase ligand library is a useful tool for PROTAC development.

Cat. No.	Product Name	Type

HY-W115731

Dextrin

Biochemical Assay Reagents

Dextrins are a group of low molecular weight carbohydrates produced by the hydrolysis of starch. Dextrin is commonly used as a thickener, stabilizer or binder in a variety of foods including baked goods, beverages and confectionary. In addition, it is used in the production of adhesives, paper and textiles. Its unique chemical properties make it an important ingredient in a variety of industrial processes, especially in construction and packaging.

HY-Y0319C1

Calcium acetate, United States Pharmacopeia (USP) Reference Standard Calcium acetate (Pharmaceutical primary standard, USP)	Biochemical Assay Reagents
Calcium acetate, United States Pharmacopeia (USP) Reference Standard (Calcium acetate (Pharmaceutical primary standard, USP)), a phosphate binder that can reduce phosphorus content, United States Pharmacopeia (USP) reference standard .

HY-B2225B

Starch (from corn)

Edible corn starch (from corn)

Biochemical Assay Reagents

Starch (from corn) is a carbohydrate extracted from the kernel of the corn plant. It contains two main components, namely amylose and amylopectin. Starches from corn have various applications in the food industry as thickeners, stabilizers and binders. It is commonly used in the production of products such as baked goods, snacks, sauces and soups. In addition, it can be used as a raw material for the production of biofuels and bioplastics.

HY-W250194

Luviquat FC 550

Biochemical Assay Reagents

Luviquat FC 550 is a cationic polymer commonly used in a variety of personal care and cosmetics. It is a viscous liquid containing quaternary ammonium groups which give it a positive charge. Luviquat FC 550 has a variety of properties suitable for these applications including its ability to provide conditioning, antistatic and film-forming properties to hair and skin. In addition, it is used as a binder in oral care products and as a flocculant in industrial water treatment.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8773

3,5,7-Trihydroxychromone	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-N6800A

Netropsin dihydrochloride	Classification of Application Fields Inflammation/Immunology Disease Research Fields	DNA/RNA Synthesis Bacterial Influenza Virus Antibiotic Orthopoxvirus
Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei . Netropsin dihydrochloride exhibits antiviral activity against the vaccinia virus .

HY-W115731

Dextrin	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Biochemical Assay Reagents Endogenous Metabolite
Dextrins are a group of low molecular weight carbohydrates produced by the hydrolysis of starch. Dextrin is commonly used as a thickener, stabilizer or binder in a variety of foods including baked goods, beverages and confectionary. In addition, it is used in the production of adhesives, paper and textiles. Its unique chemical properties make it an important ingredient in a variety of industrial processes, especially in construction and packaging.

HY-112058

Distamycin A NSC-82150	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Apoptosis
Distamycin A (NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis .

HY-B2225B

Starch (from corn) Edible corn starch (from corn)	Structural Classification Polysaccharides Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Biochemical Assay Reagents Endogenous Metabolite
Starch (from corn) is a carbohydrate extracted from the kernel of the corn plant. It contains two main components, namely amylose and amylopectin. Starches from corn have various applications in the food industry as thickeners, stabilizers and binders. It is commonly used in the production of products such as baked goods, snacks, sauces and soups. In addition, it can be used as a raw material for the production of biofuels and bioplastics.

Cat. No.	Product Name	Chemical Structure

HY-16293S

Lurbinectedin-d3
Lurbinectedin-d₃ is deuterium labeled Lurbinectedin. Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively[1].

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