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NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity.

For research use only. We do not sell to patients.

NSC243928 mesylate Chemical Structure

NSC243928 mesylate Chemical Structure

CAS No. : 59988-01-1

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5 mg USD 400 In-stock
10 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

NSC243928 mesylate Related Antibodies

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Description

NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1].

In Vitro

NSC243928 mesylate (2 μM, 24 h) induced cell death in MDA-MB-231 control cells and showed an increase in cell viability in LY6K knockdown cells, thus suggesting that NSC243928 may induce cell death through the LY6K pathway[1].
NSC243928 mesylate inhibits MDA-MB-231, Hs-578-T, BT-549 and OVCAR-8 cells with the IC50 values of 5.683 μM, 7.309 μM, 7.954 μM and 4.167 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NSC243928 mesylate Related Antibodies
Molecular Weight

503.59

Formula

C23H25N3O6S2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=S(O)(C)=O.O=S(NC1=CC=C(C(OC)=C1)NC2=C3C=CC=CC3=NC4=C2C=CC=C4)(CC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (19.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9857 mL 9.9287 mL 19.8574 mL
5 mM 0.3971 mL 1.9857 mL 3.9715 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9857 mL 9.9287 mL 19.8574 mL 49.6436 mL
5 mM 0.3971 mL 1.9857 mL 3.9715 mL 9.9287 mL
10 mM 0.1986 mL 0.9929 mL 1.9857 mL 4.9644 mL
15 mM 0.1324 mL 0.6619 mL 1.3238 mL 3.3096 mL
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NSC243928 mesylate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC24392859988-01-1NSC 243928NSC-243928OthersLY6cell growthanticancerInhibitorinhibitorinhibit

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