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United States

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Cat. No.: HY-139645

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MtDTBS-IN-1

MtDTBS-IN-1 is a particularly potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.

For research use only. We do not sell to patients.

Formula: C₁₆H₁₆N₄O₅
Molecular Weight:344.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

MtDTBS-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MtDTBS-IN-1 is a particularly potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.

All Antibiotic Isoforms :

Chemical Information

Molecular Weight 344.32
Formula C₁₆H₁₆N₄O₅
SMILES

O=C([C@@H]1CCC[C@H]1C(C(O)=O)C(O)=O)C2=CC=C(C3=NN=NN3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Schumann NC, et al. Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS): Toward Next-Generation Antituberculosis Agents. ACS Chem Biol. 2021 Nov 19;16(11):2339-2347. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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MtDTBS-IN-1

All Antibiotic Isoforms