PSMA binder-2
Based on 1 Customer Validation
PSMA binder-2 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC).
For research use only. We do not sell to patients.
- Purity: 97.35%
- CAS No.: 2149567-00-8
- Formula: C33H50N4O8
- Molecular Weight:630.77
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2149567-00-8
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Appearance Solid
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Molecular Weight 630.77
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Formula C33H50N4O8
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Color White to off-white
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SMILES
C#CC1=CC=CC(NC(NCCCC[C@@H](C(OC(C)(C)C)=O)NC(N[C@H](C(OC(C)(C)C)=O)CCC(OC(C)(C)C)=O)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (158.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5854 mL | 7.9268 mL | 15.8536 mL | 39.6341 mL |
| 5 mM | 0.3171 mL | 1.5854 mL | 3.1707 mL | 7.9268 mL | |
| 10 mM | 0.1585 mL | 0.7927 mL | 1.5854 mL | 3.9634 mL | |
| 15 mM | 0.1057 mL | 0.5285 mL | 1.0569 mL | 2.6423 mL | |
| 20 mM | 0.0793 mL | 0.3963 mL | 0.7927 mL | 1.9817 mL | |
| 25 mM | 0.0634 mL | 0.3171 mL | 0.6341 mL | 1.5854 mL | |
| 30 mM | 0.0528 mL | 0.2642 mL | 0.5285 mL | 1.3211 mL | |
| 40 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9909 mL | |
| 50 mM | 0.0317 mL | 0.1585 mL | 0.3171 mL | 0.7927 mL | |
| 60 mM | 0.0264 mL | 0.1321 mL | 0.2642 mL | 0.6606 mL | |
| 80 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4954 mL | |
| 100 mM | 0.0159 mL | 0.0793 mL | 0.1585 mL | 0.3963 mL |
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