GID4 Ligand 1
GID4 Ligand 1 (compound 88) is a cell-permeable and high-selective GID4 binder (IC50=5.4 μM; Kd=5.6 μM), binds to GID4 in cells (EC50=558 nM). GID4 Ligand 1 can be used for the synthesis of PROTACs.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 3031442-96-0
- Formule: C28H34N4O5S
- Masse moléculaire:538.66
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
IC50 & Target
IC50: 5.4 μM (GID4)[1].
In Vitro
GID4 Ligand 1 (50 μM; 1 h) shows the ability to engage endogenous GID4 protein in HEK293 cells with considerable selectivity[1].
GID4 Ligand 1 (50 μM; 10 min) binds GID4 in lysates of HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:HEK293 cells (expressing FLAG-GID4)
-
Concentration:50 μM
-
Incubation Time:1 h
-
Result:Exhibited the ability to permeate the cell membrane and engage FLAG-GID4 in living cells.
-
Cell Line:HEK293 cells (expressing FLAG-GID4)
-
Concentration:50 μM
-
Incubation Time:10 min
-
Result:Produced a Tm shift of 5.4°C.
Chemical Information
-
CAS No. 3031442-96-0
-
Masse moléculaire 538.66
-
Formule C28H34N4O5S
-
SMILES
O=C(NC)[C@@H](NC([C@H](NC(CNCC1=CC=C(OC)C=C1OC)=O)C2=CC=CS2)=O)CCC3=CC=CC=C3
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GID4 Ligand 1 Related Classifications
HY-151475 Related Classifications
Powered by Bioz