3031442-96-0
3031442-96-0
Chemical Structure
GID4 Ligand 1
- CAS No.: 3031442-96-0
- Formula:C28H34N4O5S
- Molecular Weight:538.66
IUPAC Name: (S)-2-((S)-2-(2-((2,4-dimethoxybenzyl)amino)acetamido)-2-(thiophen-2-yl)acetamido)-N-methyl-4-phenylbutanamide
InChIKey: TUQBDKJHGPFTTD-BKMJKUGQSA-N
SMILES: O=C(NC)[C@@H](NC([C@H](NC(CNCC1=CC=C(OC)C=C1OC)=O)C2=CC=CS2)=O)CCC3=CC=CC=C3
Biological Activity: GID4 Ligand 1 (compound 88) is a cell-permeable and high-selective GID4 binder (IC50=5.4 μM; Kd=5.6 μM), binds to GID4 in cells (EC50=558 nM). GID4 Ligand 1 can be used for the synthesis of PROTACs[1].
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GID4 Ligand 1 | GID4 Ligand 1 (compound 88) is a cell-permeable and high-selective GID4 binder (IC50=5.4 μM; Kd=5.6 μM), binds to GID4 in cells (EC50=558 nM). GID4 Ligand 1 can be used for the synthesis of PROTACs. | |||||||||||||||||||||
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References
Keywords
