Search Result

Results for "

enantiomers

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5-HT Receptor (6) Acyltransferase (1) Adrenergic Receptor (3) Amino Acid Derivatives (1) Amyloid-β (1) Antibiotic (1) Apoptosis (7) Arrestin (1) ATP Synthase (1) Autophagy (5) Bacterial (2) Biochemical Assay Reagents (10) Calcium Channel (3) Cannabinoid Receptor (1) Carnitine Palmitoyltransferase (CPT) (1) CFTR (1) CGRP Receptor (1) Cholinesterase (ChE) (2) COX (1) Cytochrome P450 (3) Dengue Virus (2) Deubiquitinase (1) DNA/RNA Synthesis (2) Drug Derivative (4) Drug Intermediate (2) Drug Isomer (12) Drug Metabolite (1) EGFR (1) Endogenous Metabolite (10) Enterovirus (2) Epigenetic Reader Domain (1) Eukaryotic Initiation Factor (eIF) (1) Flavivirus (2) Fluorescent Dye (1) Fructose-1,6-bisphosphate aldolase (1) Fungal (2) Galectin (1) Glucocorticoid Receptor (1) Glucokinase (1) HBV (1) Histamine Receptor (4) HIV (3) IKZF Family (1) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (5) Ligands for E3 Ligase (2) Liposome (1) mAChR (2) Mitochondrial Metabolism (1) Molecular Glues (3) Monoamine Oxidase (1) Monoamine Transporter (1) Mucin (1) Myosin (2) Na+/K+ ATPase (2) nAChR (1) Neprilysin (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (3) Orphan Nuclear Receptor (2) P-glycoprotein (1) P2X Receptor (1) Parasite (4) PDK-1 (1) Phosphodiesterase (PDE) (5) Phytohormone (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (1) PPAR (1) Prostaglandin Receptor (1) Reactive Oxygen Species (ROS) (1) Reference Standards (7) Reverse Transcriptase (1) SARS-CoV (2) Serotonin Transporter (4) Sodium Channel (2) Somatostatin Receptor (1) TNF Receptor (1) Toll-like Receptor (TLR) (2) UGT (1) β-catenin (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (7) Endocrinology (2) Infection (13) Inflammation/Immunology (20) Metabolic Disease (18) Neurological Disease (26)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (1)

128

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W048449

L-Biotin	Drug Isomer	Metabolic Disease
L-Biotin is the unnatural enantiomer of Biotin (HY-B0511) .

HY-B0105B

Levoketoconazole 1 Publications Verification (-)-Ketoconazole; (-)-Ketoconazol; (-)-R 41400	Cytochrome P450	Infection Inflammation/Immunology
Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushing’s syndrome .

HY-A0295

(R)-Propranolol hydrochloride 1 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology
(R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β₁AR and β₂AR with K_i values of 1.8 nM and 0.8 nM, respectively .

HY-D1314

FAM azide, 6-isomer 6-FAM azide	Fluorescent Dye	Others
FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .

HY-14507

YK-4-279 Maximum Cited Publications 7 Publications Verification	DNA/RNA Synthesis Apoptosis	Cancer
YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer .

HY-14658B

(R)-Thalidomide (R)-(+)-Thalidomide	Molecular Glues Ligands for E3 Ligase Autophagy Apoptosis	Metabolic Disease
(R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties .

HY-W012874

D-Threonine H-D-Thr-OH	Fructose-1,6-bisphosphate aldolase Endogenous Metabolite Drug Intermediate	Metabolic Disease
D-Threonine (H-D-Thr-OH) is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase .

HY-131445B

RR-RJW100 1 Publications Verification	Orphan Nuclear Receptor	Metabolic Disease
RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease .

HY-N0424

Cyclogalegenin Cyclogalegigenin	Others	Others
Cyclogalegenin (Cyclogalegigenin) is an isoprenoid. Cyclogalegenin can be isolated from Astragalus galegiformis. Cyclogalegenin is an isomer of cycloastragenol.

HY-W007337

3-Bromopropan-1-ol	Endogenous Metabolite	Metabolic Disease
3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly up-regulated during the estrous period of buffaloes. 3-Bromopropan-1-ol acts as an alkylating agent . 3-Bromopropan-1-ol participates in the enantioselective synthesis of nornicotine enantiomers. 3-Bromopropan-1-ol can be used in studies related to estrus detection in buffaloes .

HY-W017442

DL-Asparagine	Endogenous Metabolite	Others
DL-Asparagine is a racemic melange of the Aparagine L and D-enantiomers. DL-Asparagine has been used in growth-media for bacteria-growth .

HY-121161B

(2S,3R)-Brassinazole	Drug Isomer	Metabolic Disease
(2S,3R)-Brassinazole, the enantiomer of Brassinazole (BRZ). Brassinazole inhibits brassinosteroid (BR) biosynthesis, via acting on the oxidative processes from 6-oxo-campestanol to teasterone. (2S,3R)-Brassinazole might be the most active form of Brz .

HY-I0636

(R)-Apremilast (R)-CC-10004	Phosphodiesterase (PDE)	Inflammation/Immunology
(R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .

HY-107657

(+)-Blebbistatin 1 Publications Verification	Myosin	Others
(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective inhibitor of myosin II ATPase .

HY-W010042S3

L-Glucose-13C6 L-(-)-Glucose-¹³C₆	Isotope-Labeled Compounds	Metabolic Disease
L-Glucose- ¹³C₆ (L-(-)-Glucose- ¹³C₆) is C13-labeled L-Glucose. L-Glucose is an enantiomer of D-glucose. L-Glucose enhances food intake .

HY-15997B

(±)-U-50488 hydrochloride (±)-Trans-(1R,2R)-U-50488 hydrochloride	Opioid Receptor	Neurological Disease
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist .

HY-W420033

(S)-(+)-Etomoxir	Acyltransferase Carnitine Palmitoyltransferase (CPT)	Others
(S)-(+)-Etomoxir is the S enantiomer of Etomoxir (HY-50202). Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .

HY-121161C

(2R,3S)-Brassinazole	Phytohormone	Metabolic Disease
Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism .

HY-116196

17-HETE	Na+/K+ ATPase Cytochrome P450	Cardiovascular Disease Inflammation/Immunology
17-HETE is arachidonic acid metabolite through cytochrome P-450 pathways, which consists of 17R-HETE and 17S-HETE enantiomers. 17-HETE serves as allosteric activator of the cytochrome P450 1B1 and inhibitor of ATPase, induces cardic hypertrophy .

HY-B0265B

(S)-Nimodipine (S)-BAY-e 9736	Calcium Channel	Cardiovascular Disease
(S)-Nimodipine ((S)-BAY-e 9736) is an enantiomer of Nimodipine. Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders .

HY-B1370B

(R)-Hydroxychloroquine (R)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine . Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-W012885

(S)-Methyl 3-hydroxybutanoate	Biochemical Assay Reagents	Others
(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-13856

(R)-PS210	PDK-1	Cancer
(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC₅₀ value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of?PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment .

HY-110289

(R)-Citalopram oxalate	Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression .

HY-B1370A

(S)-Hydroxychloroquine (S)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine . Hydroxychloroquine, a synthetic antimalarial agent, inhibits Toll-like receptor 7/9 (TLR7/9) signaling, and shows efficiently inhibits SARS-CoV-2 infection in vitro .

HY-108908A

Modipafant UK-80067	Platelet-activating Factor Receptor (PAFR)	Inflammation/Immunology
Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor (PAF) antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505 .

HY-N16375

(3R,6S)-Bassiatin	Drug Metabolite Fungal ATP Synthase	Infection
(3R,6S)-Bassiatin (Compound 5) is an enantiomer of the fungal metabolite Bassiatin (HY-165143). Bassianin is a compound isolated from fungi that has the activity of inhibiting erythrocyte membrane ATPase and causing cell lysis. Its inhibitory effect on ATPase may be due to membrane disruption .

HY-B0590D

(-)-Tetrabenazine (-)-TBZ; (3S,11bS)-TBZ; (3S,11bS)-Tetrabenazine	Monoamine Transporter	Neurological Disease
(-)-Tetrabenazine ((-)-TBZ; compound 13) is an enantiomer of Tetrabenazine (HY-B0590). (+)-Tetrabenazine proves 3-fold more active than (-)-Tetrabenazine in inhibiting vesicular monoamine transporter 2 (VMAT2) .

HY-15997C

(±)-U-50488 hydrate hydrochloride (±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride	Opioid Receptor	Neurological Disease
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate hydrochloride is a selective κ opioid receptor (KOR) agonist .

HY-N16602

(±)-Blephenanthrofuran B	Others	Others
(±)-Blephenanthrofuran B is a pair of enantiomers can be found in Bletilla striata. (±)-Blephenanthrofuran B shows no cytotoxic activity against human lung cancer A549 cells .

HY-N12962A

11R(12S)-EET	Others	Others
11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .

HY-W295313

(+)-Neoisomenthol	Drug Derivative	Others
(+)-Neoisomenthol is one of the isomers of (±)-Neoisomenthol. (±)-Neoisomenthol is a compound that belongs to the class of monoterpenes. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. It is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-neoisomenthol and (-)-neoisomenthol.

HY-109022A

(3R,5R,6S)-Atogepant (3R,5R,6S)-MK-8031; (3R,5R,6S)-AGN-241689	CGRP Receptor	Neurological Disease
(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant (HY-109022). Atogepant is a calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.

HY-I0636R

(R)-Apremilast (Standard) (R)-CC-10004 (Standard)	Phosphodiesterase (PDE) Reference Standards	Inflammation/Immunology
(R)-Apremilast (Standard) is the analytical standard of (R)-Apremilast. This product is intended for research and analytical applications. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .

HY-112653A

(±)8-HETE 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid	Endogenous Metabolite	Metabolic Disease
(±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).

HY-147041A

(2S)-Selvigaltin (2S)-GB1211	Galectin	Cancer
(2S)-Selvigaltin is the S-enantiomer of Selvigaltin (HY-147041). Selvigaltin is an orally active galectin-3 (Gal-3) inhibitor .

HY-N2267

(+)-Schisandrin B	Reactive Oxygen Species (ROS)	Inflammation/Immunology
(+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart .

HY-22385B

(S)-Salsolidine	Monoamine Oxidase Endogenous Metabolite	Neurological Disease
(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (K_i=63 μM). The R enantiomer of Salsolidine is more potent than the S form (K_i=26 μM) .

HY-153093A

(1R,2R)-Elpipodect (1R,2R)-MK-8189	Phosphodiesterase (PDE)	Neurological Disease
(1R,2R)-Elpipodect ((1R,2R)-MK-8189) is the (1R,2R) enantiomer of Elpipodect (HY-153093). Elpipodect (MK-8189) is an orally active and selective PDE10A inhibitor with a K_i of 29 pM. Elpipodect can be used in research of schizophrenia .

HY-106993B

Cipralisant (enantiomer) GT-2331 (enantiomer)	Histamine Receptor	Neurological Disease
Cipralisant (GT-2331) enantiomer is the enantiomer of Cipralisant (HY-106993), Cipralisant is an orally active, potent, selective, and high affinity histamine H₃ receptor antagonist (rat K_i=0.47 nM) . Cipralisant (enantiomer) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126082

(+)-Carbovir triphosphate	HIV Reverse Transcriptase	Infection
(+)-Carbovir triphosphate is an enantiomer of Carbovir triphosphate (HY-131607). (+)-Carbovir triphosphate is an inhibitor and substrate of HIV reverse transcriptase .

HY-W751734

HU 433	Cannabinoid Receptor	Others Neurological Disease Inflammation/Immunology
HU 433 is a synthetic cannabinoid CB2 receptor agonist and is the enantiomer of HU 308 (HY-161510). HU 433 exerts its anti-inflammatory and neuroprotective effects by binding to CB2 receptors. HU 433 can be used in the study of neuroinflammation and retinal diseases .

HY-148151

(-)-5′-Noraristeromycin	HBV	Cancer
(-)-5′-Noraristeromycin is an antiviral agent. (-)-5′-Noraristeromycin also is an enantiomer of 5'-noraristeromycin and can inhibit intracellular HBV replication and virion production. (-)-5′-Noraristeromycin can be used for the research of cancer .

HY-125137

(R)-(-)-Chlorpheniramine maleate	Histamine Receptor	Inflammation/Immunology
(R)-(-)-Chlorpheniramine maleate is an enantiomer of Chlorpheniramine maleate (HY-B0286A). Chlorpheniramine maleate is a H1 antihistamines. (R)-(-)-Chlorpheniramine maleate can be used for allergic diseases such as rhinitis and urticaria research .

HY-100540B

Golgicide A-2 GCA-2	Flavivirus Dengue Virus Enterovirus	Infection
Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases .

HY-147180

Dansyl-DL-valine cyclohexylammonium	Biochemical Assay Reagents	Others
Dansyl-DL-valine cyclohexylammonium is a salt form of Dansyl-DL-valine. Dansyl-DL-valine cyclohexylammonium can be used as analyte in chromatographic separation and separation column for the separation of enantiomers and diastereomers for dansyl amino acids, aromatic carboxylic acids, and isoxazolines .

HY-110289S1

(R)-Citalopram-d4 oxalate	Isotope-Labeled Compounds Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram-d₄ (oxalate) is deuterium labeled (R)-Citalopram Oxalate. (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression .

HY-110289R

(R)-Citalopram oxalate (Standard)	Serotonin Transporter 5-HT Receptor Reference Standards	Neurological Disease
(R)-Citalopram oxalate (Standard) is the analytical standard of (R)-Citalopram oxalate. This product is intended for research and analytical applications. (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression .

HY-125630

Decacyclene	Biochemical Assay Reagents	Others
Decacyclene is a large polycyclic aromatic hydrocarbon with a triple symmetry. Decacyclene is a three-blade molecular propeller in the solid state, and crystal structure analysis shows that the molecule has a non-planar twisted form, and the crystal is chiral, which may correspond to the enantiomers of the Decacyclene propeller. Decacyclene can be used for research in chemical synthesis and materials science .

HY-N9761

Murrayanine	Others	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

Cat. No.	Product Name	Type

HY-W007337

3-Bromopropan-1-ol	Biochemical Assay Reagents
3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly up-regulated during the estrous period of buffaloes. 3-Bromopropan-1-ol acts as an alkylating agent . 3-Bromopropan-1-ol participates in the enantioselective synthesis of nornicotine enantiomers. 3-Bromopropan-1-ol can be used in studies related to estrus detection in buffaloes .

HY-W015993

Nonyl β-D-glucopyranoside n-Nonyl-β-D-glucopyranoside	Biochemical Assay Reagents
Nonyl β-D-glucopyranoside (n-Nonyl-β-D-glucopyranoside) is a surfactant that can be used in studies on interactions with lipid monolayers. Nonyl β-D-glucopyranoside can also be used for the enantiomer separation of phenoxy acid herbicides and amino acid derivatives .

HY-W012885

(S)-Methyl 3-hydroxybutanoate

Biochemical Assay Reagents

(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-NP002C

Rabbit Serum Albumin (globulin free)	Biochemical Assay Reagents
Rabbit Serum Albumin (globulin free) is a plasma protein derived from rabbits. Rabbit Serum Albumin (globulin-free) can stereoselectively bind to a variety of bioactive molecules. Rabbit Serum Albumin (globulin free) acts as the allergen Ory c RSA with cross-reactivity to other mammalian serum albumins. Rabbit Serum Albumin (globulin free) can be used for the research of allergy .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-134200

1-Palmitoyl-2-oleoyl-sn-glycerol	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-Palmitoyl-2-oleoyl-sn-glycerol is a diacylglycerol hormogonium inducer that can be isolated from the coralloid roots of Cycas revoluta. 1-Palmitoyl-2-oleoyl-sn-glycerol promotes the differentiation of filamentous Nostoc cell aggregates into motile hormogonia, and further induces the formation of dense bundle-like structures. 1-Palmitoyl-2-oleoyl-sn-glycerol is not only commonly used as a diacylglycerol standard, but also can effectively identify and separate glycerophosphate-containing phospholipid enantiomers after acetylation. 1-Palmitoyl-2-oleoyl-sn-glycerol is also used to study cyanobacterial developmental mechanisms and lipid analysis .

HY-W012874

D-Threonine H-D-Thr-OH	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Fructose-1,6-bisphosphate aldolase Endogenous Metabolite Drug Intermediate
D-Threonine (H-D-Thr-OH) is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase .

HY-N0424

Cyclogalegenin Cyclogalegigenin	Triterpenes Classification of Application Fields Leguminosae Anti-aging Terpenoids Other Diseases Plants Disease Research Fields Astragalus galegiformis	Others
Cyclogalegenin (Cyclogalegigenin) is an isoprenoid. Cyclogalegenin can be isolated from Astragalus galegiformis. Cyclogalegenin is an isomer of cycloastragenol.

HY-W017442

DL-Asparagine	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-Asparagine is a racemic melange of the Aparagine L and D-enantiomers. DL-Asparagine has been used in growth-media for bacteria-growth .

HY-N16375

(3R,6S)-Bassiatin	Natural Products Microorganisms Source Classification	Drug Metabolite Fungal ATP Synthase
(3R,6S)-Bassiatin (Compound 5) is an enantiomer of the fungal metabolite Bassiatin (HY-165143). Bassianin is a compound isolated from fungi that has the activity of inhibiting erythrocyte membrane ATPase and causing cell lysis. Its inhibitory effect on ATPase may be due to membrane disruption .

HY-N12360A

2,3-Dehydrosilybin B	Flavonols Flavonoids Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Source Classification	UGT
2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A .

HY-N16602

(±)-Blephenanthrofuran B	Bletilla striata (Thunb. ex Murray) Rchb. f. Structural Classification Orchidaceae Lignans Phenylpropanoids Plants Source Classification	Others
(±)-Blephenanthrofuran B is a pair of enantiomers can be found in Bletilla striata. (±)-Blephenanthrofuran B shows no cytotoxic activity against human lung cancer A549 cells .

HY-N12962A

11R(12S)-EET	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others
11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .

HY-112653A

(±)8-HETE 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
(±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).

HY-N2267

(+)-Schisandrin B	Structural Classification Classification of Application Fields Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Inflammation/Immunology Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
(+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart .

HY-22385B

(S)-Salsolidine	Alkaloids Salsola Plants Isoquinoline Alkaloids Source Classification Chenopodiaceae	Monoamine Oxidase Endogenous Metabolite
(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (K_i=63 μM). The R enantiomer of Salsolidine is more potent than the S form (K_i=26 μM) .

HY-N9761

Murrayanine	Alkaloids Pyrrole Alkaloids Rutaceae Murraya koenigii (L.) Spreng Plants Source Classification	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

HY-W017442R

DL-Asparagine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
DL-Asparagine is a racemic melange of the Aparagine L and D-enantiomers. DL-Asparagine has been used in growth-media for bacteria-growth .

HY-W178699

(±)-Neoisomenthol	Structural Classification Other Monoterpenes Philadelphus coronarius L. Terpenoids Hydrangeaceae Plants Source Classification	Drug Derivative
(±)-Neoisomenthol is a monoterpene. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. (±)-Neoisomenthol is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-Neoisomenthol and (-)-Neoisomenthol .

HY-N0424R

Cyclogalegenin (Standard) Cyclogalegigenin (Standard)	Triterpenes Structural Classification Leguminosae Terpenoids Plants Astragalus galegiformis	Reference Standards Others
Cyclogalegenin (Standard) is the analytical standard of Cyclogalegenin. This product is intended for research and analytical applications. Cyclogalegenin (Cyclogalegigenin) is an isoprenoid. Cyclogalegenin can be isolated from Astragalus galegiformis. Cyclogalegenin is an isomer of cycloastragenol .

HY-N11965

4'-Methoxyisoagarotetrol	Natural Products Thymelaeaceae Plants Aquilaria sinensis (Lour.) Spreng. Source Classification	Phosphodiesterase (PDE)
4'-Methoxyisoagarotetrol is chromone derivative and shows moderate PDE 3A inhibitory activity (IC₅₀=54 μM) .

HY-N19703

(+)-Hydrangenol monomethyl ether 4′-O-Methylhydrangenol	Structural Classification Flavonoids other families Plants Other Flavonoids Plagiochila gracilis Lindenb. & Gottsche Source Classification	Drug Isomer
(+)-Hydrangenol monomethyl ether is a hydrangenol-monomethyl ether (+)-enantiomer found in axenic cultures of the liverwort Plagiochila adianthoides .

HY-N12970

14S(15R)-EET	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

HY-134045

(-)-Anatoxin A	Structural Classification Alkaloids Microorganisms Other Alkaloids Source Classification	nAChR
(-)-Anatoxin A is an enantiomer of (±)-Anatoxin A (HY-N2326). (-)-Anatoxin A is a neuronal nicotinic acetylcholine receptor agonist. (-)-Anatoxin A can be used for pain and inflammation research .

HY-N17473

(+)-(6R)-Eucomegastigmane A	Structural Classification Eucommia ulmoides Oliver Terpenoids Sesquiterpenes Eucommiaceae Plants Source Classification	Drug Derivative
(+)-(6R)-Eucomegastigmane A (Compound 1a) is a grandisinane enantiomer found in the leaves of Eucommia ulmoides .

Cat. No.	Product Name	Chemical Structure

HY-W010042S3

L-Glucose-13C6
L-Glucose- ¹³C₆ (L-(-)-Glucose- ¹³C₆) is C13-labeled L-Glucose. L-Glucose is an enantiomer of D-glucose. L-Glucose enhances food intake .

HY-78131AS

(S)-(+)-Ibuprofen-d3
(S)-(+)-Ibuprofen-d₃ is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC₅₀s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects .

HY-110289S1

(R)-Citalopram-d4 oxalate
(R)-Citalopram-d₄ (oxalate) is deuterium labeled (R)-Citalopram Oxalate. (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression .

HY-B0105BS

Levoketoconazole-d3
(-)-Ketoconazole-d₃ is deuterium labeled (-)-Ketoconazole. (-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).

HY-12085S2

(Rac)-Apremilast-d5
(Rac)-Apremilast-d₅ is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .

HY-B0352BS

(R)-Mirtazapine-d3
(R)-Mirtazapine-d₃ is a deuterium labeled (R)-Mirtazapine. (R)-Mirtazapine is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4[1].

HY-B0352AS

(S)-Mirtazapine-d3
(S)-Mirtazapine-d₃ is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception.(S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].

Cat. No.	Product Name		Classification

HY-D1314

FAM azide, 6-isomer 6-FAM azide		Azide Labeling and Fluorescence Imaging
FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

enantiomers

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products