1. Immunology/Inflammation
  2. COX
  3. (S)-(+)-Ibuprofen D3

(S)-(+)-Ibuprofen D3 (Synonyms: (S)-Ibuprofen D3)

Cat. No.: HY-78131AS
Handling Instructions

(S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects.

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(S)-(+)-Ibuprofen D3 Chemical Structure

(S)-(+)-Ibuprofen D3 Chemical Structure

CAS No. : 1329643-44-8

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Description

(S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].

IC50 & Target[1]

COX-1

2.1 μM (IC50)

COX-2

1.6 μM (IC50)

Molecular Weight

209.30

Formula

C₁₃H₁₅D₃O₂

CAS No.

1329643-44-8

SMILES

OC([[email protected]](C1=CC=C(CC(C)C)C=C1)C([2H])([2H])[2H])=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(S)-(+)-Ibuprofen D3(S)-Ibuprofen D3COXCyclooxygenaseDeuteriumlabeledenantiomerCOX-1COX-2analgesicanti-inflammatoryantipyreticInhibitorinhibitorinhibit

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(S)-(+)-Ibuprofen D3
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HY-78131AS
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