RR-RJW100
Based on 1 publication(s) in Google Scholar
RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 3127027-61-3
- Formula: C28H34O
- Molecular Weight:386.57
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) RR-RJW100
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
1.5 μM
Compound: RJW100
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Agonist activity at human full length LRH1 transfected in human HeLa cells incubated for 24 hrs by renilla luciferase reporter gene assay
Agonist activity at human full length LRH1 transfected in human HeLa cells incubated for 24 hrs by renilla luciferase reporter gene assay
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[PMID: 31419141] |
Chemical Information
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CAS No. 3127027-61-3
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Appearance Liquid
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Molecular Weight 386.57
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Formula C28H34O
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Color Colorless to light yellow
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SMILES
O[C@@H]1CC[C@@]2(C(C3=CC=CC=C3)=C)C(C4=CC=CC=C4)=C(CCCCCC)C[C@@]12[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
LRH-1 is a novel regulator of neutrophil-driven immune responses within the tumor microenvironment. [Abstract]2025 Sep 18:2025.09.16.676030. PMID: 41000858
Solvent & Solubility
DMSO : 100 mg/mL (258.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5869 mL | 12.9343 mL | 25.8685 mL | 64.6713 mL |
| 5 mM | 0.5174 mL | 2.5869 mL | 5.1737 mL | 12.9343 mL | |
| 10 mM | 0.2587 mL | 1.2934 mL | 2.5869 mL | 6.4671 mL | |
| 15 mM | 0.1725 mL | 0.8623 mL | 1.7246 mL | 4.3114 mL | |
| 20 mM | 0.1293 mL | 0.6467 mL | 1.2934 mL | 3.2336 mL | |
| 25 mM | 0.1035 mL | 0.5174 mL | 1.0347 mL | 2.5869 mL | |
| 30 mM | 0.0862 mL | 0.4311 mL | 0.8623 mL | 2.1557 mL | |
| 40 mM | 0.0647 mL | 0.3234 mL | 0.6467 mL | 1.6168 mL | |
| 50 mM | 0.0517 mL | 0.2587 mL | 0.5174 mL | 1.2934 mL | |
| 60 mM | 0.0431 mL | 0.2156 mL | 0.4311 mL | 1.0779 mL | |
| 80 mM | 0.0323 mL | 0.1617 mL | 0.3234 mL | 0.8084 mL | |
| 100 mM | 0.0259 mL | 0.1293 mL | 0.2587 mL | 0.6467 mL |
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