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  4. RR-RJW100

RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease.

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RR-RJW100 Chemical Structure

RR-RJW100 Chemical Structure

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5 mg USD 750 In-stock
10 mg USD 1200 In-stock
25 mg USD 2400 In-stock
50 mg USD 3840 In-stock
100 mg USD 6140 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease[1][2].

Molecular Weight

386.57

Formula

C28H34O
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

O[C@@H]1CC[C@@]2(C(C3=CC=CC=C3)=C)C(C4=CC=CC=C4)=C(CCCCCC)C[C@@]12[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (258.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5869 mL 12.9343 mL 25.8685 mL
5 mM 0.5174 mL 2.5869 mL 5.1737 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5869 mL 12.9343 mL 25.8685 mL 64.6713 mL
5 mM 0.5174 mL 2.5869 mL 5.1737 mL 12.9343 mL
10 mM 0.2587 mL 1.2934 mL 2.5869 mL 6.4671 mL
15 mM 0.1725 mL 0.8623 mL 1.7246 mL 4.3114 mL
20 mM 0.1293 mL 0.6467 mL 1.2934 mL 3.2336 mL
25 mM 0.1035 mL 0.5174 mL 1.0347 mL 2.5869 mL
30 mM 0.0862 mL 0.4311 mL 0.8623 mL 2.1557 mL
40 mM 0.0647 mL 0.3234 mL 0.6467 mL 1.6168 mL
50 mM 0.0517 mL 0.2587 mL 0.5174 mL 1.2934 mL
60 mM 0.0431 mL 0.2156 mL 0.4311 mL 1.0779 mL
80 mM 0.0323 mL 0.1617 mL 0.3234 mL 0.8084 mL
100 mM 0.0259 mL 0.1293 mL 0.2587 mL 0.6467 mL
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RR-RJW100 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RR-RJW100OthersLRH-1SF-1RJW100enantiomerSS-RJW100metabolic homeostasisdiabetesInhibitorinhibitorinhibit

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