(+)-Blebbistatin (Standard)
(+)-Blebbistatin (Standard) is the analytical standard of (+)-Blebbistatin (HY-107657). This product is intended for research and analytical applications. (+)-Blebbistatin is the inactive enantiomer of (-)-Blebbistatin (HY-13441). (-)-Blebbistatin is a selective inhibitor of non-muscle myosin II ATPase activity.
For research use only. We do not sell to patients.
- CAS No.: 1177356-70-5
- Formula: C18H16N2O2
- Molecular Weight:292.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1177356-70-5
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Molecular Weight 292.33
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Formula C18H16N2O2
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SMILES
O[C@]12C(N(C3=CC=CC=C3)CC2)=NC4=CC=C(C)C=C4C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[3]. Ponsaerts R, et al. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellular calcium wave propagation in corneal endothelial cells. Investigative ophthalmology & visual science. 2008 Nov;49(11):4816-27. [Content Brief]
[5]. Straight AF, et al. Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (New York, N.Y.). 2003 Mar 14;299(5613):1743-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- (+)-Blebbistatin (Standard)
- 1177356-70-5
- Reference Standards
- Myosin
- myosin II motor domain
- HeLa cells
- cytoskeletal diseases
- myosin light chain phosphorylation
- Xenopus tissue culture cells
- myosin II
- primary cultured bovine corneal endothelial cells
- corneal endothelial cells
- actin-activated ATPase activity
- skeletal muscle myosin II subfragment-1
- Inhibitor
- inhibitor
- inhibit