(S,S)-Sinogliatin
(S,S)-Sinogliatin ((S,S)-HMS-5552) is the (S,S) -enantiomer of Sinogliatin. Sinogliatin is a glucokinase activator that can be used to study type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 1191996-10-7
- Formula: C22H27ClN4O5
- Molecular Weight:462.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1191996-10-7
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Molecular Weight 462.93
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Formula C22H27ClN4O5
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SMILES
CC(C[C@@H](C(NC1=NN(C=C1)C[C@@H](CO)O)=O)N2CC(OC3=CC=CC=C3Cl)=CC2=O)C
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Synonyms
(S,S)-HMS-5552; (S,S)-RO-5305552
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Song L, et al. Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration-Mean Residence Time Methods: Mechanistic Understanding of its Pharmacokinetics. Clin Pharmacokinet. 2018 Oct;57(10):1307-1323. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)