(-)-5′-Noraristeromycin
(-)-5′-Noraristeromycin is an antiviral agent. (-)-5′-Noraristeromycin also is an enantiomer of 5'-noraristeromycin and can inhibit intracellular HBV replication and virion production. (-)-5′-Noraristeromycin can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 150132-22-2
- Formula: C10H13N5O3
- Molecular Weight:251.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| FM3A | EC50 |
0.072 μM
Compound: 3
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Inhibitory activity against mammalian FM3A cell
Inhibitory activity against mammalian FM3A cell
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[PMID: 14592485] |
| Hepatoblastoma cell line | CC50 |
446 μM
Compound: 1
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Cytotoxic concentration against Hepatitis B virus in human hepatoblastoma cell line
Cytotoxic concentration against Hepatitis B virus in human hepatoblastoma cell line
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[PMID: 9622558] |
| Hepatoblastoma cell line | EC50 |
1.4 μM
Compound: 1
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Effective concentration against Hepatitis B virus in human hepatoblastoma cell line
Effective concentration against Hepatitis B virus in human hepatoblastoma cell line
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[PMID: 9622558] |
| L1210 | IC50 |
0.5 μM
Compound: (-)-2
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Inhibitory concentration on murine leukemia L1210/0 cells
Inhibitory concentration on murine leukemia L1210/0 cells
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[PMID: 8120872] |
| L929 | IC50 |
0.032 μM
Compound: (-)-2
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Inhibitory concentration on L929 cells
Inhibitory concentration on L929 cells
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[PMID: 8120872] |
| MOLT-4 | IC50 |
0.39 μM
Compound: (-)-2
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Inhibitory concentration on human T-lymphocyte Molt4 (clone 8) cells
Inhibitory concentration on human T-lymphocyte Molt4 (clone 8) cells
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[PMID: 8120872] |
In Vitro
Chemical Information
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CAS No. 150132-22-2
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Molecular Weight 251.24
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Formula C10H13N5O3
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SMILES
O[C@H]1[C@](C[C@@H]([C@H]1O)O)([H])N2C3=NC=NC(N)=C3N=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(-)-5′-Noraristeromycin Related Classifications
HY-148151 Related Classifications
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