(1S,2S,3R)-PLX-4545
Based on 1 Customer Validation
(1S,2S,3R)-PLX-4545 is the (1S,2S,3R) enantiomer of PLX-4545 (HY-159647). PLX-4545 is an orally active and selective cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). PLX-4545 can reprogram immunosuppressive regulatory T cells into pro-inflammatory effector T cells, thereby enhancing anti-tumor immune responses.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 91.78%
- No. CAS: 2892066-42-9
- Fòrmula: C28H31N3O4
- Peso molecular:473.56
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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IZKF2 |
Chemical Information
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No. CAS 2892066-42-9
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Appearance Solid
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Peso molecular 473.56
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Fòrmula C28H31N3O4
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SMILES
O=C([C@H](N(CC1=C2C=CC(O[C@@H]3[C@@H](N4CC(C5=CC=CC=C5)C4)CCCC3)=C1)C2=O)CC6)NC6=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(1S,2S,3R)-PLX-4545 Related Classifications
HY-159647B Related Classifications
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