1-Palmitoyl-2-oleoyl-sn-glycerol
Based on 1 Customer Validation
1-Palmitoyl-2-oleoyl-sn-glycerol is a diacylglycerol hormogonium inducer that can be isolated from the coralloid roots of Cycas revoluta. 1-Palmitoyl-2-oleoyl-sn-glycerol promotes the differentiation of filamentous Nostoc cell aggregates into motile hormogonia, and further induces the formation of dense bundle-like structures. 1-Palmitoyl-2-oleoyl-sn-glycerol is not only commonly used as a diacylglycerol standard, but also can effectively identify and separate glycerophosphate-containing phospholipid enantiomers after acetylation. 1-Palmitoyl-2-oleoyl-sn-glycerol is also used to study cyanobacterial developmental mechanisms and lipid analysis.
For research use only. We do not sell to patients.
- Purity : 99.56%
- CAS No.: 29541-66-0
- Formula: C37H70O5
- Molecular Weight:594.95
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
Hormogonium-inducing factor[1]
In Vitro
1-Palmitoyl-2-oleoyl-sn-glycerol (10 pmol/disc-100 nmol/disc) shows potent hormogonium-inducing activity toward Nostoc sp. strain Yaku-1, with maximum activity at 100 and 10 nmol/disc rated as (++), maintained activity rated as (+) at 1 nmol/disc, (±) at 100 pmol/disc, and no activity at 10 pmol/disc[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 29541-66-0
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Appearance Liquid (Density: 0.932±0.06 g/cm3)
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Molecular Weight 594.95
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Formula C37H70O5
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Color Colorless to light yellow
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SMILES
CCCCCCCC/C=C\CCCCCCCC(O[C@@H](CO)COC(CCCCCCCCCCCCCCC)=O)=O
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (168.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (2.10 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (587 KB)
- English - EN (587 KB)
- Français - FR (587 KB)
- Deutsch - DE (587 KB)
- Norwegian - NO (587 KB)
- Español - ES (587 KB)
- Swedish - SV (587 KB)
- Italian - IT (587 KB)
- Korean - KR (587 KB)
- Portuguese - PT (587 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6808 mL | 8.4041 mL | 16.8081 mL | 42.0203 mL |
| 5 mM | 0.3362 mL | 1.6808 mL | 3.3616 mL | 8.4041 mL | |
| 10 mM | 0.1681 mL | 0.8404 mL | 1.6808 mL | 4.2020 mL | |
| 15 mM | 0.1121 mL | 0.5603 mL | 1.1205 mL | 2.8014 mL | |
| 20 mM | 0.0840 mL | 0.4202 mL | 0.8404 mL | 2.1010 mL | |
| 25 mM | 0.0672 mL | 0.3362 mL | 0.6723 mL | 1.6808 mL | |
| 30 mM | 0.0560 mL | 0.2801 mL | 0.5603 mL | 1.4007 mL | |
| 40 mM | 0.0420 mL | 0.2101 mL | 0.4202 mL | 1.0505 mL | |
| 50 mM | 0.0336 mL | 0.1681 mL | 0.3362 mL | 0.8404 mL | |
| 60 mM | 0.0280 mL | 0.1401 mL | 0.2801 mL | 0.7003 mL | |
| 80 mM | 0.0210 mL | 0.1051 mL | 0.2101 mL | 0.5253 mL | |
| 100 mM | 0.0168 mL | 0.0840 mL | 0.1681 mL | 0.4202 mL |
1-Palmitoyl-2-oleoyl-sn-glycerol Related Classifications
HY-134200 Related Classifications
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