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(2S,3R)-Brassinazole 

Cat. No.: HY-121161B Purity: 99.94% ee.: 100%
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(2S,3R)-Brassinazole, the enantiomer of Brassinazole (BRZ). Brassinazole inhibits brassinosteroid (BR) biosynthesis, via acting on the oxidative processes from 6-oxo-campestanol to teasterone. (2S,3R)-Brassinazole might be the most active form of Brz.

For research use only. We do not sell to patients.

(2S,3R)-Brassinazole Chemical Structure

(2S,3R)-Brassinazole Chemical Structure

CAS No. : 259200-31-2

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1 mg USD 110 In-stock
5 mg USD 330 In-stock
10 mg USD 530 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (2S,3R)-Brassinazole:

(2S,3R)-Brassinazole Related Antibodies

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Description

(2S,3R)-Brassinazole, the enantiomer of Brassinazole (BRZ). Brassinazole inhibits brassinosteroid (BR) biosynthesis, via acting on the oxidative processes from 6-oxo-campestanol to teasterone. (2S,3R)-Brassinazole might be the most active form of Brz[1][2][3].

IC50 & Target

Brassinosteroid (BR) biosynthesis[1]
In Vitro

Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(2S,3R)-Brassinazole Related Antibodies
Molecular Weight

327.81

Formula

C18H18ClN3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@](O)(C1=CC=CC=C1)[C@H](N2C=NC=N2)CC3=CC=C(C=C3)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (61.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0505 mL 15.2527 mL 30.5055 mL
5 mM 0.6101 mL 3.0505 mL 6.1011 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0505 mL 15.2527 mL 30.5055 mL 76.2637 mL
5 mM 0.6101 mL 3.0505 mL 6.1011 mL 15.2527 mL
10 mM 0.3051 mL 1.5253 mL 3.0505 mL 7.6264 mL
15 mM 0.2034 mL 1.0168 mL 2.0337 mL 5.0842 mL
20 mM 0.1525 mL 0.7626 mL 1.5253 mL 3.8132 mL
25 mM 0.1220 mL 0.6101 mL 1.2202 mL 3.0505 mL
30 mM 0.1017 mL 0.5084 mL 1.0168 mL 2.5421 mL
40 mM 0.0763 mL 0.3813 mL 0.7626 mL 1.9066 mL
50 mM 0.0610 mL 0.3051 mL 0.6101 mL 1.5253 mL
60 mM 0.0508 mL 0.2542 mL 0.5084 mL 1.2711 mL
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(2S,3R)-Brassinazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(2S,3R)-Brassinazole259200-31-2OthersBrassinazole EnantiomerInhibitorinhibitorinhibit

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