Camptothecin (Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT)

Name: Camptothecin
Brand: MedChemExpress
SKU: HY-16560
Rating: 5.0 (68 reviews)

Cat. No.: HY-16560 Purity: 99.77%: Data Sheet
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Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC₅₀ of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.

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CAS No. : 7689-03-4

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	견적 받기
50 g	견적 받기

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고객리뷰

Based on 68 publication(s) in Google Scholar

Other Forms of Camptothecin:

Camptothecin-d₅ In-stock
(R)-Camptothecin 견적 받기
Camptothecin (Standard) 견적 받기

68 Publications Citing Use of MCE Camptothecin

Cell Proliferation/Viability Assay

: Camptothecin purchased from MedChemExpress. Usage Cited in: Arch Cancer Res. 2023 Jan 30.; Camptothecin (CPT; 10^-5 -10^-10 M; 72 h) demonstrates a strong antitumor activity and an inhibitory of proliferation (IC₅₀ = 25.36 nM) in U937 cells.

: Camptothecin purchased from MedChemExpress. Usage Cited in: Cell Death Differ. 2020 Nov;27(11):3162-3176. [Abstract]; 293T cells transfected with Flag-TopBP1 and GFP-tagged RBMX and its domain (RRM, RBM1CTR, and C-RBD) are treated with 100 nM CPT for 24 h and subjected to immunoprecipitation with Flag-beads. Immunoprecipitates are immunoblotted with Flag and GFP antibodies, respectively.

: Camptothecin purchased from MedChemExpress. Usage Cited in: Nat Commun. 2019 Aug 21;10(1):3761. [Abstract]; Genotoxic stress-induced β-catenin signaling is activated via a TCF- or FOXO-independent mechanism. Representative images of the subcellular localization of β-catenin in the indicated cells treated with CPT (10 μM, 1 h), IR (10 Gy), and CDDP (10 μM, 1 h), as analyzed by immunofluorescence staining.

: Camptothecin purchased from MedChemExpress. Usage Cited in: Nat Commun. 2018 Oct 8;9(1):4139. [Abstract]; One hour after treated with UV or 2 h after treated with MMS, Camptothecin (CPT) (10 μM), or Doxorubicin (DOX; 0.5 μM), HEK293T cells expressing HA-SUMO2 and His-RhoB are subjected to sumoylation assay to detect the SUMO2 conjugation of RhoB.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC₅₀ of 679 nM^[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells^[2]^[3].

IC₅₀ & Target^[3]

Topoisomerase I

679 nM (IC₅₀)

Camptothecins

Cellular Effect

Cell Line	Type	Value	Description	References
184B5	IC₅₀	4.96 3 Compound: Camptothecin	Antiproliferative activity against human 184B5 cells after 72 hrs by SRB assay Antiproliferative activity against human 184B5 cells after 72 hrs by SRB assay	[PMID: 26602827]
184B5	IC₅₀	4.96 3 Compound: Camptothecin	Antiproliferative activity against human 184B5 cells after 72 hrs by SRB assay Antiproliferative activity against human 184B5 cells after 72 hrs by SRB assay	[PMID: 26602827]
1A9	ED₅₀	3.2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human 1A9 cells by sulforhodamine B assay Cytotoxicity against human 1A9 cells by sulforhodamine B assay	[PMID: 17350834]
1A9	ED₅₀	3.2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human 1A9 cells by sulforhodamine B assay Cytotoxicity against human 1A9 cells by sulforhodamine B assay	[PMID: 17350834]
4T1	IC₅₀	0.17 3 Compound: 1; CPT	Antiproliferative activity against mouse 4T1 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against mouse 4T1 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
4T1	IC₅₀	0.17 3 Compound: 1; CPT	Antiproliferative activity against mouse 4T1 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against mouse 4T1 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
4T1	IC₅₀	> 300 3 Compound: CPT	Antiproliferative activity against mouse 4T1 cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against mouse 4T1 cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
786-0	IC₅₀	0.015 3 Compound: CPT	Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
786-0	IC₅₀	0.015 3 Compound: CPT	Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
A2780	IC₅₀	0.004 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 72 hrs by MTS method Cytotoxicity against human A2780 cells after 72 hrs by MTS method	[PMID: 11858737]
A2780	IC₅₀	0.029 3 Compound: 1; CPT	Antiproliferative activity against human A2780 cells after 96 hrs by MTT assay Antiproliferative activity against human A2780 cells after 96 hrs by MTT assay	[PMID: 27871039]
833K	IC₅₀	10 1 Compound: CPT	Tested in vitro for growth inhibitory activity against 833K (human teratorcarcinoma) cells Tested in vitro for growth inhibitory activity against 833K (human teratorcarcinoma) cells	10.1016/S0960-894X(97)10181-0
A 172	IC₅₀	0.14 3 Compound: 13 ((S)-CPT, Camptothecin)	In vitro cytotoxicity against A172 human tumor cell lines. In vitro cytotoxicity against A172 human tumor cell lines.	10.1016/0960-894X(96)00132-1
A2780	IC₅₀	0.07 6 Compound: camptothecin	Cytotoxicity against human A2780 cells by clonogenic assay Cytotoxicity against human A2780 cells by clonogenic assay	[PMID: 16499333]
A2780	IC₅₀	0.2 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 24 hrs by MTT assay Cytotoxicity against human A2780 cells after 24 hrs by MTT assay	[PMID: 20961093]
A 172	IC₅₀	0.14 3 Compound: CPT ((S)-Camptothecin)	Cytotoxicity against A-172 human tumor cell lines Cytotoxicity against A-172 human tumor cell lines	10.1016/0960-894X(96)00131-X
A-375	IC₅₀	0.013 3 Compound: Camptothecin	Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
A2780	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human A2780 cells after 4 days by MTT assay Cytotoxicity against human A2780 cells after 4 days by MTT assay	[PMID: 18554906]
A-375	IC₅₀	0.187 3 Compound: CPT, Camptothecin	Cytotoxicity against human A375 cells after 24 hrs by MTT assay Cytotoxicity against human A375 cells after 24 hrs by MTT assay	[PMID: 24980118]
A2780	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 22044245]
A2780	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 19453174]
A-375	IC₅₀	0.66 3 Compound: CPT	Cytotoxicity against human A-375 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human A-375 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
A2780	IC₅₀	0.28 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 18095653]
A-427	IC₅₀	24 1 Compound: CPT	Antiproliferative activity measured against A427 human lung carcinoma Antiproliferative activity measured against A427 human lung carcinoma	[PMID: 9876111]
A2780	IC₅₀	0.3 3 Compound: CPT	Cytotoxicity against human A2780 cells after 4 days by MTT assay Cytotoxicity against human A2780 cells after 4 days by MTT assay	[PMID: 19702283]
A-431	IC₅₀	0.011 3 Compound: 1, CPT	Cytotoxicity against human A431 cells after 72 hrs by trypan blue assay Cytotoxicity against human A431 cells after 72 hrs by trypan blue assay	[PMID: 21071230]
A2780	IC₅₀	0.3 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 19256478]
A2780	GI₅₀	0.46 3 Compound: CPT	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
A2780	IC₅₀	0.9 3 Compound: camptothecin	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 25237727]
A20	IC₅₀	179.2 3 Compound: CPT	Cytostatic activity against mouse A20 cells after 24 hrs by CCK-8 assay Cytostatic activity against mouse A20 cells after 24 hrs by CCK-8 assay	[PMID: 38278140]
A2780	IC₅₀	13 1 Compound: CPT	Cytotoxicity against human A2780 cells after 72 hrs by MTT assay Cytotoxicity against human A2780 cells after 72 hrs by MTT assay	[PMID: 24900725]
A2780	GI₅₀	0.46 3 Compound: CPT	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
A2780	IC₅₀	7 1 Compound: Cpt	Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay	[PMID: 22749423]
A2780	IC₅₀	0.004 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 72 hrs by MTS method Cytotoxicity against human A2780 cells after 72 hrs by MTS method	[PMID: 11858737]
A-375	IC₅₀	0.013 3 Compound: Camptothecin	Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
A2780	IC₅₀	0.007 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against A2780 (human ovarian cancer) In vitro cytotoxicity against A2780 (human ovarian cancer)	[PMID: 14552770]
A2780	IC₅₀	0.029 3 Compound: 1; CPT	Antiproliferative activity against human A2780 cells after 96 hrs by MTT assay Antiproliferative activity against human A2780 cells after 96 hrs by MTT assay	[PMID: 27871039]
A-375	IC₅₀	0.187 3 Compound: CPT, Camptothecin	Cytotoxicity against human A375 cells after 24 hrs by MTT assay Cytotoxicity against human A375 cells after 24 hrs by MTT assay	[PMID: 24980118]
A2780	IC₅₀	0.07 6 Compound: camptothecin	Cytotoxicity against human A2780 cells by clonogenic assay Cytotoxicity against human A2780 cells by clonogenic assay	[PMID: 16499333]
A-375	IC₅₀	0.66 3 Compound: CPT	Cytotoxicity against human A-375 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human A-375 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
A2780	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human A2780 cells after 4 days by MTT assay Cytotoxicity against human A2780 cells after 4 days by MTT assay	[PMID: 18554906]
A-431	IC₅₀	0.011 3 Compound: 1, CPT	Cytotoxicity against human A431 cells after 72 hrs by trypan blue assay Cytotoxicity against human A431 cells after 72 hrs by trypan blue assay	[PMID: 21071230]
A549	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 24180210]
A2780	IC₅₀	0.2 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 24 hrs by MTT assay Cytotoxicity against human A2780 cells after 24 hrs by MTT assay	[PMID: 20961093]
A2780	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 22044245]
A549	IC₅₀	< 1 3 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28511910]
A2780	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 19453174]
A549	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
A549	GI₅₀	0.003 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
A2780	IC₅₀	0.28 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 18095653]
A549	IC₅₀	0.004 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 48 hrs Cytotoxicity against human A549 cells after 48 hrs	[PMID: 17673337]
A2780	IC₅₀	0.28 3 Compound: camptothecin	Cytotoxicity against human A2780 cells Cytotoxicity against human A2780 cells	[PMID: 19916529]
A2780	IC₅₀	0.3 3 Compound: CPT	Cytotoxicity against human A2780 cells after 4 days by MTT assay Cytotoxicity against human A2780 cells after 4 days by MTT assay	[PMID: 19702283]
A549	IC₅₀	0.006 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells after 96 hrs by MTT assay Antiproliferative activity against human A549 cells after 96 hrs by MTT assay	[PMID: 27871039]
A549	GI₅₀	0.007 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 48 hrs by MTT assay Growth inhibition of human A549 cells after 48 hrs by MTT assay	[PMID: 23357037]
A2780	IC₅₀	0.3 3 Compound: camptothecin	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 19256478]
A2780	IC₅₀	0.9 3 Compound: camptothecin	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 25237727]
A549	IC₅₀	0.008 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 22325897]
A2780	IC₅₀	13 1 Compound: CPT	Cytotoxicity against human A2780 cells after 72 hrs by MTT assay Cytotoxicity against human A2780 cells after 72 hrs by MTT assay	[PMID: 24900725]
A549	IC₅₀	0.009 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
A2780	IC₅₀	7 1 Compound: Cpt	Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay	[PMID: 22749423]
A549	IC₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 4 days by MTT assay Cytotoxicity against human A549 cells after 4 days by MTT assay	[PMID: 18554906]
A549	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
A549	IC₅₀	0.0158 3 Compound: 1, CPT	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 23102893]
A549	IC₅₀	0.016 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 25003995]
A549	IC₅₀	0.016 3 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B colorimetric assay Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B colorimetric assay	[PMID: 26994847]
A549	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
A549	IC₅₀	0.03 3 Compound: Camptothecin	Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
A549	IC₅₀	0.039 3 Compound: CPT	Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
A549	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 30543429]
A549	IC₅₀	0.04 3 Compound: 1, CPT	Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
A549	IC₅₀	0.047 3 Compound: 1, CPT	Antitumor activity against human A549/ATCC cells by SRB method Antitumor activity against human A549/ATCC cells by SRB method	[PMID: 19541483]
A549	IC₅₀	0.057 3 Compound: CPT	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 20942490]
A549	IC₅₀	0.058 3 Compound: CPT	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 19345580]
A549	IC₅₀	0.067 3 Compound: CPT, campothecin	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 17827007]
A549	IC₅₀	0.069 3 Compound: CPT	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 21353568]
A549	IC₅₀	0.069 3 Compound: camptothecin	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 17498951]
A549	IC₅₀	0.072 6 Compound: CPT	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 21684168]
A549	IC₅₀	0.074 3 Compound: CPT	In-vitro antitumor activity against human A549 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human A549 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
A549	IC₅₀	0.09 3 Compound: CPT; 1	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30509782]
A549	IC₅₀	0.091 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 21873069]
A549	GI₅₀	0.099 3 Compound: CPT	Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
A549	IC₅₀	0.1 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
A549	IC₅₀	0.1 3 Compound: CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 26226379]
A549	IC₅₀	0.12 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 27344492]
A549	IC₅₀	0.17 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
A549	GI₅₀	0.17 3 Compound: 1, CPT	Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
A549	GI₅₀	0.2 3 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 21388138]
A549	GI₅₀	0.21 3 Compound: 1	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 30336023]
A549	IC₅₀	0.24 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
A549	IC₅₀	0.26 3 Compound: CPT	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 28351590]
A549	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 22044245]
A549	GI₅₀	0.31 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
A549	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human A549 cells after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
A549	EC₅₀	4.17 1 Compound: 1; CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 38421819]
A549	ED₅₀	6.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 17350834]
A549	IC₅₀	0.35 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
A549	GI₅₀	0.003 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
A549	IC₅₀	0.37 3 Compound: CPT	Cytotoxicity against human A549 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
A549	IC₅₀	0.46 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27416553]
A549	GI₅₀	0.007 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 48 hrs by MTT assay Growth inhibition of human A549 cells after 48 hrs by MTT assay	[PMID: 23357037]
A549	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
A549	IC₅₀	0.47 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
A549	GI₅₀	0.099 3 Compound: CPT	Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
A549	IC₅₀	0.65 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24069881]
A549	IC₅₀	0.7 3 Compound: Camptothecin	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 28506750]
A549	GI₅₀	0.17 3 Compound: 1, CPT	Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
A549	IC₅₀	1 1 Compound: CPT	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
A549	GI₅₀	0.2 3 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 21388138]
A549	IC₅₀	1 1 Compound: CPT	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
A549	GI₅₀	0.21 3 Compound: 1	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 30336023]
A549	GI₅₀	0.31 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
A549	IC₅₀	1 1 Compound: I; CPT	Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay	[PMID: 31229877]
A549	GI₅₀	2.8 3 Compound: 1, camptothecin	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 18180162]
A549	IC₅₀	1 1 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
A549	GI₅₀	2.8 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 20662543]
A549	IC₅₀	1 1 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
A549	GI₅₀	5.69 14 Compound: 1; CPT	Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay	[PMID: 38421819]
A549	IC₅₀	1 1 Compound: camptothecin	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 25237727]
A549	IC₅₀	1 3 Compound: I; CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
A549	IC₅₀	0.004 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 48 hrs Cytotoxicity against human A549 cells after 48 hrs	[PMID: 17673337]
A549	IC₅₀	0.006 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells after 96 hrs by MTT assay Antiproliferative activity against human A549 cells after 96 hrs by MTT assay	[PMID: 27871039]
A549	IC₅₀	1.3 3 Compound: 3	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 25084144]
A549	IC₅₀	1.31 3 Compound: CPT	Cytotoxicity against against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
A549	IC₅₀	0.008 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 22325897]
A549	IC₅₀	0.008 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against A549 (human lung cancer) In vitro cytotoxicity against A549 (human lung cancer)	[PMID: 14552770]
A549	IC₅₀	1.56 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
A549	IC₅₀	1.6 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26188908]
A549	IC₅₀	0.009 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
A549	IC₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 4 days by MTT assay Cytotoxicity against human A549 cells after 4 days by MTT assay	[PMID: 18554906]
A549	IC₅₀	13.64 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28462840]
A549	IC₅₀	0.0158 3 Compound: 1, CPT	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 23102893]
A549	IC₅₀	2.21 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30109008]
A549	IC₅₀	2.53 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against AS-49 (human lung caner ) cell line was determined by SRB assay In vitro antiproliferative activity of compound against AS-49 (human lung caner ) cell line was determined by SRB assay	[PMID: 12639541]
A549	IC₅₀	0.016 3 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B colorimetric assay Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B colorimetric assay	[PMID: 26994847]
A549	IC₅₀	0.016 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 25003995]
A549	IC₅₀	2.61 3 Compound: CPT	Antiproliferative activity against human A549 cells after 3 days by MTT assay Antiproliferative activity against human A549 cells after 3 days by MTT assay	[PMID: 23084702]
A549	IC₅₀	2.8 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
A549	IC₅₀	0.021 3 Compound: CPT	Cytotoxicity against human A549 cells measured after 72 hrs Cytotoxicity against human A549 cells measured after 72 hrs	[PMID: 38716896]
A549	IC₅₀	0.03 3 Compound: Camptothecin	Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
A549	GI₅₀	2.8 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 20662543]
A549	GI₅₀	2.8 3 Compound: 1, camptothecin	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 18180162]
A549	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
A549	IC₅₀	26.45 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25599951]
A549	IC₅₀	0.039 3 Compound: CPT	Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
A549	IC₅₀	0.04 3 Compound: 1, CPT	Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human A549 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
A549	IC₅₀	3.1 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 19256478]
A549	IC₅₀	3.12 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 18095653]
A549	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 30543429]
A549	IC₅₀	3.32 3 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 30902399]
A549	IC₅₀	0.047 3 Compound: 1, CPT	Antitumor activity against human A549/ATCC cells by SRB method Antitumor activity against human A549/ATCC cells by SRB method	[PMID: 19541483]
A549	IC₅₀	3.6 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 20961093]
A549	IC₅₀	0.057 3 Compound: CPT	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 20942490]
A549	IC₅₀	32.11 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay	[PMID: 30853330]
A549	IC₅₀	0.058 3 Compound: CPT	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 19345580]
A549	IC₅₀	0.067 3 Compound: CPT, campothecin	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 17827007]
A549	IC₅₀	33.8 1 Compound: 1, CPT	Cytotoxicity against human A549 after 72 hrs by SRB assay Cytotoxicity against human A549 after 72 hrs by SRB assay	[PMID: 22647222]
A549	IC₅₀	37.05 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 72 hrs ny MTT assay Cytotoxicity against human A549 cells after 72 hrs ny MTT assay	[PMID: 23974020]
A549	IC₅₀	0.069 3 Compound: 1, CPT	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 21095131]
A549	IC₅₀	4.43 3 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30685528]
A549	IC₅₀	0.069 3 Compound: CPT	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 21353568]
A549	IC₅₀	5.379 1 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT method Cytotoxicity against human A549 cells after 48 hrs by MTT method	[PMID: 20063889]
A549	IC₅₀	0.069 3 Compound: camptothecin	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 17498951]
A549	IC₅₀	0.072 6 Compound: CPT	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 21684168]
A549	IC₅₀	5.5 3 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
A549	IC₅₀	0.074 3 Compound: CPT	In-vitro antitumor activity against human A549 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human A549 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
A549	IC₅₀	5.93 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
A549	IC₅₀	5.93 3 Compound: CPT	Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
A549	IC₅₀	0.09 3 Compound: CPT; 1	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30509782]
A549	IC₅₀	50.88 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay	[PMID: 30853330]
A549	IC₅₀	0.091 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 21873069]
A549	ED₅₀	6.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human A549 cells by sulforhodamine B assay Cytotoxicity against human A549 cells by sulforhodamine B assay	[PMID: 17350834]
A549	IC₅₀	0.1 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
A549	IC₅₀	67 1 Compound: 1, CPT, NSC-100880	Cytotoxicity against human A549 cells by WST assay Cytotoxicity against human A549 cells by WST assay	[PMID: 23578545]
A549	IC₅₀	0.1 3 Compound: CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 26226379]
A549	IC₅₀	0.12 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 27344492]
A549	IC₅₀	67 1 Compound: CPT	Cytotoxicity against A549 tumor cell line determined by WST-1 assay Cytotoxicity against A549 tumor cell line determined by WST-1 assay	[PMID: 10841808]
A549	IC₅₀	0.17 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
A549	IC₅₀	8.63 1 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 28927790]
A549	IC₅₀	8.63 1 Compound: 1; CPT	Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
A549	IC₅₀	0.24 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
A549	IC₅₀	8.87 3 Compound: Camptothecin	Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
A549	IC₅₀	0.26 3 Compound: CPT	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 28351590]
A549	IC₅₀	8.9 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
A549	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 22044245]
A549	IC₅₀	99 1 Compound: CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24900725]
A549	IC₅₀	0.32 1 Compound: 1; CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 38421819]
ADR5000 cell line	IC₅₀	0.011 3 Compound: Camptothecin	Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay	[PMID: 28233677]
A549	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human A549 cells after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
A549	IC₅₀	0.32 14 Compound: 1; CPT	Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 38421819]
ADR5000 cell line	IC₅₀	0.3 3 Compound: CPT	Cytotoxicity against human CEM/ADR5000 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human CEM/ADR5000 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
A549	IC₅₀	0.35 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
AGS	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
AGS	IC₅₀	0.02 3 Compound: 1, CPT	Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
A549	IC₅₀	0.37 3 Compound: CPT	Cytotoxicity against human A549 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
AGS	GI₅₀	23.76 3 Compound: 1, camptothecin	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 18180162]
A549	IC₅₀	0.39 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth by MTT assay	[PMID: 38169246]
A549	IC₅₀	0.39 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells Antiproliferative activity against human A549 cells	[PMID: 38665827]
AGS	IC₅₀	23.76 3 Compound: CPT	Antiproliferative activity against human AGS cells incubated for 72 hrs by MTT assay Antiproliferative activity against human AGS cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
A549	IC₅₀	0.46 3 Compound: 1; CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27416553]
B16-F10	IC₅₀	2.78 3 Compound: Camptothecin	Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay	[PMID: 24685545]
A549	IC₅₀	0.47 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
Bel-7402	IC₅₀	0.014 3 Compound: 1; CPT	Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 27871039]
A549	IC₅₀	0.65 3 Compound: 1, CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24069881]
Bel-7402	IC₅₀	0.17 3 Compound: 1, CPT	Cytotoxicity against human BEL-7402 cells after 4 days by MTT assay Cytotoxicity against human BEL-7402 cells after 4 days by MTT assay	[PMID: 18554906]
A549	IC₅₀	0.7 3 Compound: Camptothecin	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 28506750]
Bel-7402	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 22044245]
A549	IC₅₀	1 1 Compound: CPT	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
Bel-7402	IC₅₀	12.5 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 19256478]
Bel-7402	IC₅₀	12.5 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 18095653]
A549	IC₅₀	1 x 10^-3 3 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
Bel-7402	IC₅₀	2.72 6 Compound: 1 Camptothecin	In vitro cytotoxicity against Bel7402 cell line (human liver cancer) using MTT assay In vitro cytotoxicity against Bel7402 cell line (human liver cancer) using MTT assay	[PMID: 15225719]
A549	IC₅₀	1 x 10^-3 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
A549	IC₅₀	1 x 10^-3 3 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
Bel-7402	IC₅₀	6.3 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells by MTT assay Cytotoxicity against human Bel7402 cells by MTT assay	[PMID: 25237727]
BEL-7404 tumor cell line	IC₅₀	0.14 3 Compound: CPT	Cytotoxicity against human Bel7404 cells after 72 hrs by MTT assay Cytotoxicity against human Bel7404 cells after 72 hrs by MTT assay	[PMID: 26226379]
A549	IC₅₀	1 x 10^-3 3 Compound: I; CPT	Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK8 assay	[PMID: 31229877]
A549	IC₅₀	1 x 10^-3 3 Compound: camptothecin	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 25237727]
BEL-7404 tumor cell line	IC₅₀	0.4 3 Compound: CPT	Antiproliferative activity against human Bel7404 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human Bel7404 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
A549	IC₅₀	1 3 Compound: I; CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
BGC-823	IC₅₀	0.04 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells by MTT assay Cytotoxicity against human BGC823 cells by MTT assay	[PMID: 25237727]
A549	IC₅₀	1.3 3 Compound: 3	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 25084144]
BGC-823	IC₅₀	0.057 3 Compound: 1; CPT	Antiproliferative activity against human BGC823 cells after 96 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 27871039]
BGC-823	IC₅₀	1.27 3 Compound: 1; CPT	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 27416553]
A549	IC₅₀	1.31 3 Compound: CPT	Cytotoxicity against against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
BGC-823	IC₅₀	9.67 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 18095653]
A549	IC₅₀	1.56 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
A549	IC₅₀	1.6 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26188908]
BGC-823	IC₅₀	9.7 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 19256478]
BJ	IC₅₀	> 40 3 Compound: Camp	Cytotoxicity against human BJ cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human BJ cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
A549	IC₅₀	106.3 3 Compound: CPT	Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
A549	IC₅₀	13.64 3 Compound: Camptothecin	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28462840]
BT-20	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human BT20 cells after 3 days by SRB assay Cytotoxicity against human BT20 cells after 3 days by SRB assay	[PMID: 23142674]
A549	IC₅₀	14 1 Compound: CPT	In Vitro cytotoxicity against human lung cancer cell line (A549) In Vitro cytotoxicity against human lung cancer cell line (A549)	[PMID: 11334569]
BT-20	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human BT20 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human BT20 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
BT-20	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
A549	IC₅₀	2.21 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30109008]
BT-474	IC₅₀	12.75 3 Compound: CPT	Cytotoxicity against human BT474 cells after 3 days by SRB assay Cytotoxicity against human BT474 cells after 3 days by SRB assay	[PMID: 23142674]
A549	IC₅₀	2.53 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against AS-49 (human lung caner ) cell line was determined by SRB assay In vitro antiproliferative activity of compound against AS-49 (human lung caner ) cell line was determined by SRB assay	[PMID: 12639541]
A549	IC₅₀	2.61 3 Compound: CPT	Antiproliferative activity against human A549 cells after 3 days by MTT assay Antiproliferative activity against human A549 cells after 3 days by MTT assay	[PMID: 23084702]
BT-474	IC₅₀	7 3 Compound: Camptothecin	Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay	[PMID: 26988802]
BT-483	GI₅₀	1.03 3 Compound: CPT	Cytotoxicity against human BT-483 cells after 48 hrs by MTT assay Cytotoxicity against human BT-483 cells after 48 hrs by MTT assay	[PMID: 20662543]
A549	IC₅₀	2.8 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
A549	IC₅₀	26.45 3 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25599951]
BXPC-3	IC₅₀	0.24 3 Compound: 1, CPT	Cytotoxicity against human BXPC3 cells after 4 days by MTT assay Cytotoxicity against human BXPC3 cells after 4 days by MTT assay	[PMID: 18554906]
A549	IC₅₀	3.1 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 19256478]
C6	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human C6 cells measured after 72 hrs by MTT assay Antiproliferative activity against human C6 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
A549	IC₅₀	3.12 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 18095653]
CA46	IC₅₀	0.52 3 Compound: CPT	Cytotoxicity against human CA46 cells after 48 hrs by MTT assay Cytotoxicity against human CA46 cells after 48 hrs by MTT assay	[PMID: 26188908]
A549	IC₅₀	3.32 3 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 30902399]
Caco-2	IC₅₀	0.131 3 Compound: CPT, Camptothecin	Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay	[PMID: 24980118]
A549	IC₅₀	3.6 3 Compound: camptothecin	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 20961093]
Caco-2	IC₅₀	9.55 3 Compound: Camptothecin	Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 21843907]
CAKI-2	IC₅₀	3.96 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against Caki-2 (human renal caner ) cell line was determined by SRB assay In vitro antiproliferative activity of compound against Caki-2 (human renal caner ) cell line was determined by SRB assay	[PMID: 12639541]
A549	IC₅₀	32.1 3 Compound: Camptophecin	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 33421712]
A549	IC₅₀	32.11 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay	[PMID: 30853330]
CAMA-1	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human CAMA1 cells after 3 days by SRB assay Cytotoxicity against human CAMA1 cells after 3 days by SRB assay	[PMID: 23142674]
CAMA-1	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
A549	IC₅₀	33.8 1 Compound: 1, CPT	Cytotoxicity against human A549 after 72 hrs by SRB assay Cytotoxicity against human A549 after 72 hrs by SRB assay	[PMID: 22647222]
CAPAN-1	IC₅₀	0.21 3 Compound: CPT	Cytotoxicity against human Capan1 cells after 72 hrs by XTT assay Cytotoxicity against human Capan1 cells after 72 hrs by XTT assay	[PMID: 30017114]
A549	IC₅₀	330 3 Compound: C (20)(S)-1	In vitro cytotoxicity against human tumor cell line A549 In vitro cytotoxicity against human tumor cell line A549	[PMID: 10576688]
Ca-Ski	IC₅₀	1.8 3 Compound: Camptothecin	Antiproliferative activity against human CaSki cells after 24 hrs by crystal violet staining-based assay Antiproliferative activity against human CaSki cells after 24 hrs by crystal violet staining-based assay	[PMID: 29407986]
A549	IC₅₀	37.05 3 Compound: Camptothecin	Cytotoxicity against human A549 cells after 72 hrs ny MTT assay Cytotoxicity against human A549 cells after 72 hrs ny MTT assay	[PMID: 23974020]
CCRF-CEM	GI₅₀	0.002 3 Compound: camptothecin	Growth inhibition of human CEM cells by Alamar blue assay Growth inhibition of human CEM cells by Alamar blue assay	[PMID: 17418582]
A549	IC₅₀	4 3 Compound: Camptothecin	Inhibition topoisomerase 1 in human A549 cells assessed as conversion of supercoiled pBR322 DNA to relaxed form Inhibition topoisomerase 1 in human A549 cells assessed as conversion of supercoiled pBR322 DNA to relaxed form	[PMID: 11430001]
CCRF-CEM	GI₅₀	0.002 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
A549	IC₅₀	4.43 3 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30685528]
A549	IC₅₀	5.379 1 Compound: CPT	Cytotoxicity against human A549 cells after 48 hrs by MTT method Cytotoxicity against human A549 cells after 48 hrs by MTT method	[PMID: 20063889]
CCRF-CEM	IC₅₀	0.002 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells by MTT assay Cytotoxicity against human CCRF-CEM cells by MTT assay	[PMID: 30543429]
CCRF-CEM	CC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay	[PMID: 22884523]
A549	IC₅₀	5.5 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
CCRF-CEM	CC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay	[PMID: 22047799]
A549	IC₅₀	5.5 3 Compound: Camptothecin	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
A549	IC₅₀	5.93 3 Compound: CPT	Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
CCRF-CEM	IC₅₀	0.003 3 Compound: CPT	Antiproliferative activity against human CCRF-CEM cells by MTT assay Antiproliferative activity against human CCRF-CEM cells by MTT assay	[PMID: 17254669]
CCRF-CEM	IC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay	[PMID: 28233677]
A549	IC₅₀	5.93 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
A549	IC₅₀	50.88 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay	[PMID: 30853330]
CCRF-CEM	GI₅₀	0.007 3 Compound: 1	Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay	[PMID: 30336023]
A549	IC₅₀	67 1 Compound: 1, CPT, NSC-100880	Cytotoxicity against human A549 cells by WST assay Cytotoxicity against human A549 cells by WST assay	[PMID: 23578545]
CCRF-CEM	GI₅₀	0.023 1 Compound: camptothecin	Cytotoxicity against human CCRF-CEM cells after 48 hrs by cell titer-blue assay Cytotoxicity against human CCRF-CEM cells after 48 hrs by cell titer-blue assay	[PMID: 19743858]
CCRF-CEM	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against p38-proficient human CCRF-CEM cells after 3 days by MTT assay Cytotoxicity against p38-proficient human CCRF-CEM cells after 3 days by MTT assay	[PMID: 19203291]
A549	IC₅₀	67 1 Compound: CPT	Cytotoxicity against A549 tumor cell line determined by WST-1 assay Cytotoxicity against A549 tumor cell line determined by WST-1 assay	[PMID: 10841808]
A549	IC₅₀	7.8 3 Compound: CPT	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
CCRF-CEM	IC₅₀	0.08 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
CCRF-CEM	IC₅₀	0.84 1 Compound: CPT	Inhibitory concentration against CEM cell growth after incubation in liquid medium for 72 h Inhibitory concentration against CEM cell growth after incubation in liquid medium for 72 h	[PMID: 15916431]
A549	IC₅₀	8.63 1 Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 28927790]
A549	IC₅₀	8.63 1 Compound: 1; CPT	Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
CCRF-CEM	GI₅₀	43.21 1 Compound: camptothecin	Cytotoxicity against human CCRF-CEM/C2 cells after 48 hrs by cell titer-blue assay Cytotoxicity against human CCRF-CEM/C2 cells after 48 hrs by cell titer-blue assay	[PMID: 19743858]
CCRF-SB	IC₅₀	0.003 3 Compound: CPT	Antiproliferative activity against human CCRF-SB cells by MTT assay Antiproliferative activity against human CCRF-SB cells by MTT assay	[PMID: 17254669]
A549	IC₅₀	8.87 3 Compound: Camptothecin	Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
CCRF-SB	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay	[PMID: 22884523]
A549	IC₅₀	8.9 3 Compound: CPT	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
CCRF-SB	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay	[PMID: 22047799]
A549	IC₅₀	99 1 Compound: CPT	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24900725]
CEM/C2	GI₅₀	> 1 3 Compound: camptothecin	Growth inhibition of topoisomerase 1 mutated CEM/C2 cells by Alamar blue assay Growth inhibition of topoisomerase 1 mutated CEM/C2 cells by Alamar blue assay	[PMID: 17418582]
A549	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 24180210]
CEM/C2	IC₅₀	5385 1 Compound: CPT	Inhibitory concentration against CEM/C2 cell growth after incubation in liquid medium for 72 h Inhibitory concentration against CEM/C2 cell growth after incubation in liquid medium for 72 h	[PMID: 15916431]
A549	IC₅₀	< 1 3 Compound: CPT	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28511910]
A549	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
CNE	IC₅₀	0.34 3 Compound: CPT	Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay	[PMID: 30125725]
AGS	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
CNE-2	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
AGS	GI₅₀	23.76 3 Compound: 1, camptothecin	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 18180162]
CNE-2	IC₅₀	0.98 3 Compound: CPT	Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 30125725]
Col2	IC₅₀	0.045 3 Compound: CPT	Cytotoxicity against human Col2 cells by MTT assay Cytotoxicity against human Col2 cells by MTT assay	[PMID: 21353568]
AGS	IC₅₀	0.02 3 Compound: 1, CPT	Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human AGS cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
AGS	IC₅₀	23.76 3 Compound: CPT	Antiproliferative activity against human AGS cells incubated for 72 hrs by MTT assay Antiproliferative activity against human AGS cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
Col2	IC₅₀	0.045 3 Compound: camptothecin	Cytotoxicity against human Col2 cells by SRB assay Cytotoxicity against human Col2 cells by SRB assay	[PMID: 17498951]
COLO 205	IC₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay	[PMID: 24041234]
B16-F10	IC₅₀	2.78 3 Compound: Camptothecin	Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay	[PMID: 24685545]
CRL-7065 cell line	CC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human CRL7065 cells after 96 hrs by MTT assay Cytotoxicity against human CRL7065 cells after 96 hrs by MTT assay	[PMID: 22884523]
CRL-7065 cell line	CC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human CRL7065 cells after 96 hrs by MTT assay Cytotoxicity against human CRL7065 cells after 96 hrs by MTT assay	[PMID: 22047799]
CRL-7065 cell line	IC₅₀	0.5 3 Compound: CPT	Antiproliferative activity against human CRL7065 cells by MTT assay Antiproliferative activity against human CRL7065 cells by MTT assay	[PMID: 17254669]
CT26.WT	IC₅₀	0.43 3 Compound: CPT	Antiproliferative activity against mouse CT26.WT cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against mouse CT26.WT cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
Detroit 551	GI₅₀	0.99 3 Compound: CPT	Cytotoxicity against human Detroit 551 cells after 48 hrs by MTT assay Cytotoxicity against human Detroit 551 cells after 48 hrs by MTT assay	[PMID: 20662543]
Detroit 551	IC₅₀	0.99 3 Compound: CPT	Antiproliferative activity against human Detroit 551 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human Detroit 551 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
Detroit 551	GI₅₀	0.99 3 Compound: CPT	Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay	[PMID: 20591678]
DU-145	IC₅₀	0.01 3 Compound: CPT	Antiproliferative activity against human DU145 cells by MTT assay Antiproliferative activity against human DU145 cells by MTT assay	[PMID: 17254669]
DU-145	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 24800942]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells after 48 hrs by SRB assay Cytotoxicity against human DU145 cells after 48 hrs by SRB assay	[PMID: 21823606]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells by SRB assay Cytotoxicity against human DU145 cells by SRB assay	[PMID: 24502276]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells by SRB assay Antiproliferative activity against human DU145 cells by SRB assay	[PMID: 21710981]
BGC-823	IC₅₀	0.04 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells by MTT assay Cytotoxicity against human BGC823 cells by MTT assay	[PMID: 25237727]
DU-145	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
BGC-823	IC₅₀	0.057 3 Compound: 1; CPT	Antiproliferative activity against human BGC823 cells after 96 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 27871039]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells after 48 hrs Antiproliferative activity against human DU145 cells after 48 hrs	[PMID: 27070999]
BGC-823	IC₅₀	0.21 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells Cytotoxicity against human BGC823 cells	[PMID: 19916529]
DU-145	CC₅₀	0.015 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs by MTT assay Cytotoxicity against human DU145 cells after 96 hrs by MTT assay	[PMID: 22047799]
DU-145	IC₅₀	0.015 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs Cytotoxicity against human DU145 cells after 96 hrs	[PMID: 22276775]
BGC-823	IC₅₀	1.27 3 Compound: 1; CPT	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 27416553]
BGC-823	IC₅₀	9.67 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 18095653]
DU-145	IC₅₀	0.016 3 Compound: CPT	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 30543429]
BGC-823	IC₅₀	9.7 3 Compound: camptothecin	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 19256478]
DU-145	GI₅₀	0.019 3 Compound: CPT	Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
BJ	IC₅₀	> 40 3 Compound: Camp	Cytotoxicity against human BJ cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human BJ cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
DU-145	IC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay	[PMID: 26945111]
BT-20	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
DU-145	IC₅₀	0.02 3 Compound: camptothecin	Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay	[PMID: 25936262]
BT-20	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human BT20 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human BT20 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
DU-145	IC₅₀	0.02 3 Compound: Camptothecin	Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
BT-20	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human BT20 cells after 3 days by SRB assay Cytotoxicity against human BT20 cells after 3 days by SRB assay	[PMID: 23142674]
DU-145	GI₅₀	0.021 3 Compound: 1	Growth inhibition of human DU145 cells after 72 hrs by MTT assay Growth inhibition of human DU145 cells after 72 hrs by MTT assay	[PMID: 30336023]
BT-474	IC₅₀	12.75 3 Compound: CPT	Cytotoxicity against human BT474 cells after 3 days by SRB assay Cytotoxicity against human BT474 cells after 3 days by SRB assay	[PMID: 23142674]
DU-145	IC₅₀	0.0287 3 Compound: 1, CPT	Cytotoxicity against human DU145 cells by SRB assay Cytotoxicity against human DU145 cells by SRB assay	[PMID: 23102893]
BT-474	IC₅₀	7 3 Compound: Camptothecin	Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay	[PMID: 26988802]
DU-145	IC₅₀	0.029 3 Compound: 1, CPT	Cytotoxicity against human DU145 cells after 72 hrs by SRB assay Cytotoxicity against human DU145 cells after 72 hrs by SRB assay	[PMID: 25003995]
DU-145	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human DU145 cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
BT-483	GI₅₀	1.03 3 Compound: CPT	Cytotoxicity against human BT-483 cells after 48 hrs by MTT assay Cytotoxicity against human BT-483 cells after 48 hrs by MTT assay	[PMID: 20662543]
BXPC-3	IC₅₀	0.24 3 Compound: 1, CPT	Cytotoxicity against human BXPC3 cells after 4 days by MTT assay Cytotoxicity against human BXPC3 cells after 4 days by MTT assay	[PMID: 18554906]
DU-145	IC₅₀	0.07 3 Compound: 45	Anti-proliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Anti-proliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 33143937]
DU-145	CC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs by MTT assay Cytotoxicity against human DU145 cells after 96 hrs by MTT assay	[PMID: 22884523]
BXPC-3	IC₅₀	62.5 1 Compound: CPT	Cytotoxicity against human BXPC-3 cells assessed as inhibition of cell growth Cytotoxicity against human BXPC-3 cells assessed as inhibition of cell growth	[PMID: 37806498]
Bel-7402	IC₅₀	0.007 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against Bel7402 (human liver cancer) In vitro cytotoxicity against Bel7402 (human liver cancer)	[PMID: 14552770]
DU-145	IC₅₀	0.1 3 Compound: CPT	Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay	[PMID: 25799376]
Bel-7402	IC₅₀	0.014 3 Compound: 1; CPT	Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 27871039]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK8 assay Cytotoxicity against human DU145 cells after 2 days by CCK8 assay	[PMID: 26361737]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay	[PMID: 25481396]
Bel-7402	IC₅₀	0.17 3 Compound: 1, CPT	Cytotoxicity against human BEL-7402 cells after 4 days by MTT assay Cytotoxicity against human BEL-7402 cells after 4 days by MTT assay	[PMID: 18554906]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
Bel-7402	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 22044245]
Bel-7402	IC₅₀	12.5 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 18095653]
DU-145	GI₅₀	0.21 3 Compound: CPT	Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
Bel-7402	IC₅₀	12.5 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 19256478]
DU-145	GI₅₀	0.21 3 Compound: CPT	Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
Bel-7402	IC₅₀	2.72 6 Compound: 1 Camptothecin	In vitro cytotoxicity against Bel7402 cell line (human liver cancer) using MTT assay In vitro cytotoxicity against Bel7402 cell line (human liver cancer) using MTT assay	[PMID: 15225719]
DU-145	IC₅₀	0.21 3 Compound: CPT	Antiproliferative activity against human DU-145 cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human DU-145 cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
Bel-7402	IC₅₀	6.3 3 Compound: camptothecin	Cytotoxicity against human Bel7402 cells by MTT assay Cytotoxicity against human Bel7402 cells by MTT assay	[PMID: 25237727]
DU-145	IC₅₀	0.31 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 21419530]
C6	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human C6 cells measured after 72 hrs by MTT assay Antiproliferative activity against human C6 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
DU-145	IC₅₀	0.38 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
CA46	IC₅₀	0.52 3 Compound: CPT	Cytotoxicity against human CA46 cells after 48 hrs by MTT assay Cytotoxicity against human CA46 cells after 48 hrs by MTT assay	[PMID: 26188908]
DU-145	IC₅₀	0.39 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay	[PMID: 24013413]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
CAKI-2	IC₅₀	3.96 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against Caki-2 (human renal caner ) cell line was determined by SRB assay In vitro antiproliferative activity of compound against Caki-2 (human renal caner ) cell line was determined by SRB assay	[PMID: 12639541]
CAMA-1	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 21601964]
CAMA-1	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human CAMA1 cells after 3 days by SRB assay Cytotoxicity against human CAMA1 cells after 3 days by SRB assay	[PMID: 23142674]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
DU-145	IC₅₀	0.61 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 21115246]
CAMA-1	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against human CAMA-1 cells assessed as cell growth inhibition Antiproliferative activity against human CAMA-1 cells assessed as cell growth inhibition	[PMID: 38107170]
CAPAN-1	IC₅₀	0.21 3 Compound: CPT	Cytotoxicity against human Capan1 cells after 72 hrs by XTT assay Cytotoxicity against human Capan1 cells after 72 hrs by XTT assay	[PMID: 30017114]
DU-145	IC₅₀	0.66 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay	[PMID: 19939682]
DU-145	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
CCD 19Lu	IC₅₀	2 6 Compound: Camptothecin (CPT)	Tested for the cytostatic activity as inhibitory concentration against CCD-19Lu (human normal pulmonary) cells Tested for the cytostatic activity as inhibitory concentration against CCD-19Lu (human normal pulmonary) cells	10.1016/S0960-894X(97)00071-1
DU-145	IC₅₀	0.95 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay	[PMID: 25062006]
DU-145	IC₅₀	1 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 19836231]
DU-145	IC₅₀	1.06 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
DU-145	IC₅₀	1.46 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 3 days Cytotoxicity against human DU145 cells after 3 days	[PMID: 19954977]
DU-145	IC₅₀	1.99 3 Compound: Camptothecin	Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
DU-145	ED₅₀	10.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human DU145 cells by sulforhodamine B assay Cytotoxicity against human DU145 cells by sulforhodamine B assay	[PMID: 17350834]
DU-145	GI₅₀	18.2 1 Compound: 1	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 24502276]
DU-145	IC₅₀	2.37 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 22318164]
DU-145	IC₅₀	3.2 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by MTT assay Cytotoxicity against human DU145 cells after 4 days by MTT assay	[PMID: 20619511]
CCRF-CEM	CC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay	[PMID: 22047799]
DU-145	IC₅₀	3.57 3 Compound: camptothecin	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 20093033]
CCRF-CEM	CC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells after 96 hrs by MTT assay	[PMID: 22884523]
DU-145	IC₅₀	4.01 3 Compound: CPT	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 24904965]
CCRF-CEM	GI₅₀	0.002 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
CCRF-CEM	GI₅₀	0.002 3 Compound: camptothecin	Growth inhibition of human CEM cells by Alamar blue assay Growth inhibition of human CEM cells by Alamar blue assay	[PMID: 17418582]
DU-145	IC₅₀	9.29 3 Compound: CPT	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 22819942]
CCRF-CEM	GI₅₀	0.007 3 Compound: 1	Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay	[PMID: 30336023]
ECa-109 cell line	IC₅₀	9.52 3 Compound: CPT	Cytotoxicity against human ECA109 cells assessed as decrease in cell proliferation after 48 hrs by MTT assay Cytotoxicity against human ECA109 cells assessed as decrease in cell proliferation after 48 hrs by MTT assay	[PMID: 27667553]
Erythrocyte	EC₅₀	429.9 6 Compound: Camptothecin	Hemolytic activity in Homo sapiens (human) Erythrocyte after 30 min Hemolytic activity in Homo sapiens (human) Erythrocyte after 30 min	10.1007/s00044-010-9381-7
CCRF-CEM	GI₅₀	0.023 1 Compound: camptothecin	Cytotoxicity against human CCRF-CEM cells after 48 hrs by cell titer-blue assay Cytotoxicity against human CCRF-CEM cells after 48 hrs by cell titer-blue assay	[PMID: 19743858]
CCRF-CEM	GI₅₀	2 1 Compound: Camptothecin	Growth inhibition of human CEM cells Growth inhibition of human CEM cells	[PMID: 23750455]
Fibroblast	IC₅₀	459.3 1 Compound: camptothecin	Cytotoxicity against human Fibroblasts by SRB assay Cytotoxicity against human Fibroblasts by SRB assay	[PMID: 21410162]
CCRF-CEM	GI₅₀	43.21 1 Compound: camptothecin	Cytotoxicity against human CCRF-CEM/C2 cells after 48 hrs by cell titer-blue assay Cytotoxicity against human CCRF-CEM/C2 cells after 48 hrs by cell titer-blue assay	[PMID: 19743858]
GLC4 cell line	IC₅₀	10 1 Compound: Cpt	Cytotoxicity against human GLC4 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human GLC4 cells after 72 hrs by sulforhodamine B assay	[PMID: 22749423]
H22	IC₅₀	0.54 3 Compound: 1; CPT	Antiproliferative activity against mouse H22 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against mouse H22 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
CCRF-CEM	IC₅₀	0.002 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells by MTT assay Cytotoxicity against human CCRF-CEM cells by MTT assay	[PMID: 30543429]
CCRF-CEM	IC₅₀	0.003 3 Compound: CPT	Antiproliferative activity against human CCRF-CEM cells by MTT assay Antiproliferative activity against human CCRF-CEM cells by MTT assay	[PMID: 17254669]
H69AR	IC₅₀	> 300 1 Compound: 1a	Cytotoxicity against human H69AR cells overexpressing MDR1 after 72 hrs by alamar blue assay Cytotoxicity against human H69AR cells overexpressing MDR1 after 72 hrs by alamar blue assay	[PMID: 21341674]
CCRF-CEM	IC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by resazurin reduction assay	[PMID: 28233677]
HBL-100	GI₅₀	0.23 3 Compound: Camptothecin	Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay	[PMID: 23831507]
CCRF-CEM	IC₅₀	0.005 3 Compound: CPT	Cytotoxicity against human CEM cells Cytotoxicity against human CEM cells	[PMID: 22305342]
HBL-100	GI₅₀	0.23 3 Compound: CPT	Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HCC70	IC₅₀	0.044 3 Compound: Camptothecin	Antiproliferative activity against human HCC70 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human HCC70 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
CCRF-CEM	IC₅₀	0.005 6 Compound: Camptothecin (CPT)	Tested for the cytostatic activity as inhibitory concentration against CCRF-CEM human leukemia cells Tested for the cytostatic activity as inhibitory concentration against CCRF-CEM human leukemia cells	10.1016/S0960-894X(97)00071-1
HCCLM9	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HCCLM9 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HCCLM9 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
CCRF-CEM	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against p38-proficient human CCRF-CEM cells after 3 days by MTT assay Cytotoxicity against p38-proficient human CCRF-CEM cells after 3 days by MTT assay	[PMID: 19203291]
CCRF-CEM	IC₅₀	0.08 3 Compound: CPT	Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
HCT-116	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 3 days by SRB assay Cytotoxicity against human HCT116 cells after 3 days by SRB assay	[PMID: 23142674]
CCRF-CEM	IC₅₀	0.84 1 Compound: CPT	Inhibitory concentration against CEM cell growth after incubation in liquid medium for 72 h Inhibitory concentration against CEM cell growth after incubation in liquid medium for 72 h	[PMID: 15916431]
HCT-116	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 22409771]
HCT-116	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
CCRF-CEM	IC₅₀	5.3 3 Compound: Camptothecin	Cytotoxicity in human leukemic CCRF-CEM cells. Cytotoxicity in human leukemic CCRF-CEM cells.	[PMID: 14667232]
HCT-116	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
CCRF-SB	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay	[PMID: 22047799]
HCT-116	IC₅₀	≤ 0.1 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
CCRF-SB	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay Cytotoxicity against human CCRF-SB cells after 96 hrs by MTT assay	[PMID: 22884523]
CCRF-SB	IC₅₀	0.003 3 Compound: CPT	Antiproliferative activity against human CCRF-SB cells by MTT assay Antiproliferative activity against human CCRF-SB cells by MTT assay	[PMID: 17254669]
HCT-116	IC₅₀	0.00015 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 25247770]
CEM/C2	GI₅₀	1000 1 Compound: Camptothecin	Growth inhibition of multidrug-resistant human CEM/C2 cells Growth inhibition of multidrug-resistant human CEM/C2 cells	[PMID: 23750455]
HCT-116	IC₅₀	0.003 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
CEM/C2	GI₅₀	> 1 3 Compound: camptothecin	Growth inhibition of topoisomerase 1 mutated CEM/C2 cells by Alamar blue assay Growth inhibition of topoisomerase 1 mutated CEM/C2 cells by Alamar blue assay	[PMID: 17418582]
HCT-116	IC₅₀	0.009 3 Compound: CPT	Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
HCT-116	IC₅₀	0.009 3 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by MTS method Cytotoxicity against human HCT116 cells after 72 hrs by MTS method	[PMID: 11858737]
CEM/C2	IC₅₀	5385 1 Compound: CPT	Inhibitory concentration against CEM/C2 cell growth after incubation in liquid medium for 72 h Inhibitory concentration against CEM/C2 cell growth after incubation in liquid medium for 72 h	[PMID: 15916431]
HCT-116	GI₅₀	0.009 3 Compound: CPT	Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
HCT-116	GI₅₀	0.009 3 Compound: 1	Growth inhibition of human HCT116 cells after 72 hrs by MTT assay Growth inhibition of human HCT116 cells after 72 hrs by MTT assay	[PMID: 30336023]
HCT-116	GI₅₀	0.009 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
HCT-116	IC₅₀	0.0115 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28454671]
HCT-116	IC₅₀	0.013 3 Compound: CPT	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 30543429]
HCT-116	IC₅₀	0.016 3 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by WST-8 assay Cytotoxicity against human HCT116 cells after 72 hrs by WST-8 assay	[PMID: 24033077]
HCT-116	IC₅₀	0.017 3 Compound: CPT	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
HCT-116	IC₅₀	0.02 3 Compound: CPT	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
HCT-116	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
HCT-116	GI₅₀	0.03 3 Compound: 1	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 24800942]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay	[PMID: 21823606]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells by SRB assay Cytotoxicity against human HCT116 cells by SRB assay	[PMID: 24502276]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells by SRB assay Antiproliferative activity against human HCT116 cells by SRB assay	[PMID: 21710981]
CNE	IC₅₀	0.34 3 Compound: CPT	Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay	[PMID: 30125725]
CNE-2	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
HCT-116	GI₅₀	0.03 3 Compound: 2	Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
CNE-2	IC₅₀	0.98 3 Compound: CPT	Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 30125725]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells after 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs	[PMID: 27070999]
COLO 201	IC₅₀	27 3 Compound: Camptothecin	Cytotoxicity against human COLO201 cells assessed as inhibition of cell growth incubated for 24 hrs by WST-1 assay Cytotoxicity against human COLO201 cells assessed as inhibition of cell growth incubated for 24 hrs by WST-1 assay	[PMID: 39018435]
HCT-116	IC₅₀	0.04 3 Compound: CPT	In-vitro antitumor activity against human HCT-116 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human HCT-116 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
HCT-116	IC₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HCT-116 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HCT-116	GI₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
HCT-116	GI₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HCT-116	IC₅₀	0.07 3 Compound: 1, CPT	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24069881]
HCT-116	GI₅₀	0.075 3 Compound: CPT	Growth inhibition of human HCT116 cells expressing siTOP1 incubated for 72 hrs by MTT assay Growth inhibition of human HCT116 cells expressing siTOP1 incubated for 72 hrs by MTT assay	[PMID: 31176097]
HCT-116	GI₅₀	0.075 3 Compound: 1	Growth inhibition of human HCT116 cells expressing TOP1 siRNA after 72 hrs by MTT assay Growth inhibition of human HCT116 cells expressing TOP1 siRNA after 72 hrs by MTT assay	[PMID: 30336023]
HCT-116	GI₅₀	0.075 3 Compound: CPT	Cytotoxicity against human HCT116 cells expressing TOP1 siRNA assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells expressing TOP1 siRNA assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
HCT-116	GI₅₀	0.083 3 Compound: 1, CPT	Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HCT-116	IC₅₀	0.09 3 Compound: 1; CPT	Antiproliferative activity against human HCT-116 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HCT-116	IC₅₀	0.09 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 26226379]
HCT-116	IC₅₀	0.11 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 3 days by MTT assay Antiproliferative activity against human HCT116 cells after 3 days by MTT assay	[PMID: 23084702]
HCT-116	IC₅₀	0.12 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 28351590]
HCT-116	IC₅₀	0.13 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 3 days by XTT assay Antiproliferative activity against human HCT116 cells after 3 days by XTT assay	[PMID: 19691293]
HCT-116	IC₅₀	0.159 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay	[PMID: 28477443]
HCT-116	IC₅₀	0.159 3 Compound: Camptothecin	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 27318980]
HCT-116	GI₅₀	0.195 3 Compound: Camptothecin	Antiproliferative activity against human HCT-116 p53-/- cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HCT-116 p53-/- cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HCT-116	IC₅₀	0.25 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 33158579]
HCT-116	IC₅₀	0.4 3 Compound: CPT	Antitumor activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
HCT-116	IC₅₀	0.6 3 Compound: CPT	Cytotoxicity against human HCT-116 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
HCT-116	IC₅₀	1.88 3 Compound: CPT	Cytotoxicity against against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
COLO 205	IC₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay	[PMID: 24041234]
COLO 205	IC₅₀	5.4 1 Compound: 1	Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]thymidine into cellular DNA of human colorectal cells (COLO 205) Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]thymidine into cellular DNA of human colorectal cells (COLO 205)	[PMID: 10479293]
HCT-116	IC₅₀	1.88 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
CT26	IC₅₀	34 1 Compound: camptothecin	Antiproliferative activity against mouse CT26 cell line Antiproliferative activity against mouse CT26 cell line	[PMID: 16686539]
HCT-116	GI₅₀	17.38 1 Compound: 1	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24502276]
CT26.WT	IC₅₀	0.43 3 Compound: CPT	Antiproliferative activity against mouse CT26.WT cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against mouse CT26.WT cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
HCT-116	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 19655762]
HCT-116	IC₅₀	2.01 1 Compound: Camptothecin	Cytotoxicity against human HCT-116 cells assessed as cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell viability incubated for 24 hrs by MTT assay	[PMID: 35567964]
HCT-116	IC₅₀	2.3 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 4 days by MTT assay Cytotoxicity against human HCT116 cells after 4 days by MTT assay	[PMID: 20619511]
HCT-116	IC₅₀	2.77 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 3 days Cytotoxicity against human HCT116 cells after 3 days	[PMID: 19954977]
Ca-Ski	IC₅₀	1.8 3 Compound: Camptothecin	Antiproliferative activity against human CaSki cells after 24 hrs by crystal violet staining-based assay Antiproliferative activity against human CaSki cells after 24 hrs by crystal violet staining-based assay	[PMID: 29407986]
Ca-Ski	IC₅₀	> 300 3 Compound: CPT	Antiproliferative activity against human Ca-Ski cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against human Ca-Ski cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
HCT-116	IC₅₀	22.9 1 Compound: 1, CPT	Cytotoxicity against human HCT116 after 72 hrs by SRB assay Cytotoxicity against human HCT116 after 72 hrs by SRB assay	[PMID: 22647222]
HCT-116	IC₅₀	3.97 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 2 days Cytotoxicity against human HCT116 cells after 2 days	[PMID: 21419530]
HCT-116	GI₅₀	35.48 1 Compound: 1	Cytotoxicity against human HCT116 cells transfected with Top1-siRNA after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells transfected with Top1-siRNA after 72 hrs by MTT assay	[PMID: 24502276]
HCT-116	IC₅₀	6.7 3 Compound: CPT	Cytotoxicity against human HCT116 cells measured after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
HCT-116	IC₅₀	8.5 1 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay	[PMID: 32952994]
HCT-15	IC₅₀	0.0014 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
HCT-15	IC₅₀	0.02 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
HCT-15	IC₅₀	0.049 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human HCT15 cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
HCT-15	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
HCT-15	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
HCT-15	IC₅₀	0.067 3 Compound: Camptothecin	Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HCT-15	IC₅₀	0.08 3 Compound: CPT, campothecin	Cytotoxicity against human HCT15 cells by SRB assay Cytotoxicity against human HCT15 cells by SRB assay	[PMID: 17827007]
HCT-15	IC₅₀	0.08 3 Compound: CPT	Antiproliferative activity against human HCT-15 cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human HCT-15 cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
HCT-15	IC₅₀	0.083 3 Compound: camptothecin	Cytotoxicity against human HCT15 cells after 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs	[PMID: 17673337]
HCT-15	IC₅₀	0.096 6 Compound: CPT	Cytotoxicity against human HCT15 cells by sulforhodamine B assay Cytotoxicity against human HCT15 cells by sulforhodamine B assay	[PMID: 21684168]
HCT-15	IC₅₀	0.166 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay	[PMID: 21873069]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay	[PMID: 25481396]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28384547]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 22318164]
HCT-15	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay	[PMID: 26361737]
HCT-15	IC₅₀	0.31 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HCT-15	IC₅₀	0.35 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
HCT-15	IC₅₀	0.42 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay	[PMID: 24013413]
HCT-15	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 21601964]
Caco-2	IC₅₀	0.131 3 Compound: CPT, Camptothecin	Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay	[PMID: 24980118]
Caco-2	IC₅₀	9.55 3 Compound: Camptothecin	Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 21843907]
HCT-15	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
HCT-15	IC₅₀	0.52 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
HCT-15	IC₅₀	0.6 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28068603]
HCT-15	IC₅₀	0.76 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28633898]
HCT-15	IC₅₀	0.76 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay	[PMID: 19939682]
HCT-15	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells by MTT assay Cytotoxicity against human HCT15 cells by MTT assay	[PMID: 21115246]
Col2	ED₅₀	57 1 Compound: camptothecin	Cytotoxicity against human Col2 cells Cytotoxicity against human Col2 cells	[PMID: 15043407]
HCT-15	IC₅₀	1.29 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay	[PMID: 26927425]
Col2	IC₅₀	0.045 3 Compound: 1, CPT	Cytotoxicity against human Col2 cells Cytotoxicity against human Col2 cells	[PMID: 21095131]
Col2	IC₅₀	0.045 3 Compound: CPT	Cytotoxicity against human Col2 cells by MTT assay Cytotoxicity against human Col2 cells by MTT assay	[PMID: 21353568]
HCT-15	IC₅₀	1.38 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
HCT-15	IC₅₀	1.59 3 Compound: Camptothecin	Antiproliferative activity against human HCT-15 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human HCT-15 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
Col2	IC₅₀	0.045 3 Compound: camptothecin	Cytotoxicity against human Col2 cells by SRB assay Cytotoxicity against human Col2 cells by SRB assay	[PMID: 17498951]
DC3F	IC₅₀	6 1 Compound: CPT	Tested in vitro for growth inhibitory activity against DC-3F (hamster lung) cells Tested in vitro for growth inhibitory activity against DC-3F (hamster lung) cells	10.1016/S0960-894X(97)10181-0
HCT-15	IC₅₀	1.98 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay	[PMID: 25062006]
HCT-15	IC₅₀	10.07 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 24904965]
DLD-1	IC₅₀	0.21 3 Compound: 13 ((S)-CPT, Camptothecin)	In vitro cytotoxicity against DLD-1 human tumor cell lines. In vitro cytotoxicity against DLD-1 human tumor cell lines.	10.1016/0960-894X(96)00132-1
DLD-1	IC₅₀	0.21 3 Compound: CPT ((S)-Camptothecin)	Cytotoxicity against DLD-1 human tumor cell lines Cytotoxicity against DLD-1 human tumor cell lines	10.1016/0960-894X(96)00131-X
HCT-15	IC₅₀	2.82 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay	[PMID: 26945111]
DLD-1	IC₅₀	14000 3 Compound: C (20)(S)-1	In vitro cytotoxicity against human tumor cell line DLD-1 In vitro cytotoxicity against human tumor cell line DLD-1	[PMID: 10576688]
HCT-15	IC₅₀	2.82 3 Compound: camptothecin	Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay	[PMID: 25936262]
DU-145	CC₅₀	0.015 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs by MTT assay Cytotoxicity against human DU145 cells after 96 hrs by MTT assay	[PMID: 22047799]
HCT-15	IC₅₀	3 1 Compound: camptothecin	Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay	[PMID: 19655762]
DU-145	CC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs by MTT assay Cytotoxicity against human DU145 cells after 96 hrs by MTT assay	[PMID: 22884523]
HCT-15	IC₅₀	6.08 3 Compound: CPT	Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay	[PMID: 26334499]
DU-145	ED₅₀	10.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human DU145 cells by sulforhodamine B assay Cytotoxicity against human DU145 cells by sulforhodamine B assay	[PMID: 17350834]
HCT-15	IC₅₀	7.1 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 26988802]
HCT-15	IC₅₀	9.92 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 22819942]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cell line Antiproliferative activity against human DU145 cell line	[PMID: 16442283]
HCT-8	IC₅₀	< 0.005 6 Compound: 1 Camptothecin	In vitro cytotoxicity against HCT-8 cell line (human colon cancer) using MTT assay In vitro cytotoxicity against HCT-8 cell line (human colon cancer) using MTT assay	[PMID: 15225719]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 17402722]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells Antiproliferative activity against human DU145 cells	[PMID: 18630891]
HCT-8	IC₅₀	< 0.013 3 Compound: CPT	Cytotoxicity against human HCT8 cells after 3 days by MTT assay Cytotoxicity against human HCT8 cells after 3 days by MTT assay	[PMID: 20392545]
HCT-8	IC₅₀	0.024 3 Compound: 1; CPT	Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 27871039]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 19783447]
HCT-8	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 22044245]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 20630766]
HCT-8	IC₅₀	3.15 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 18095653]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells by SRB assay Antiproliferative activity against human DU145 cells by SRB assay	[PMID: 21710981]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells after 48 hrs by SRB assay Cytotoxicity against human DU145 cells after 48 hrs by SRB assay	[PMID: 21823606]
HCT-8	IC₅₀	3.2 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 19256478]
HCT-8	IC₅₀	3.6 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 25237727]
DU-145	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human DU145 cells by SRB assay Cytotoxicity against human DU145 cells by SRB assay	[PMID: 24502276]
DU-145	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 24800942]
HEC-1B cell line	IC₅₀	8.64 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against HEC-1-B (human endometrical caner ) cell line was determined by SRB assay In vitro antiproliferative activity of compound against HEC-1-B (human endometrical caner ) cell line was determined by SRB assay	[PMID: 12639541]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells after 48 hrs Antiproliferative activity against human DU145 cells after 48 hrs	[PMID: 27070999]
HEK293	IC₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay	[PMID: 28027871]
DU-145	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human DU145 cells assessed as growth inhibition Antiproliferative activity against human DU145 cells assessed as growth inhibition	[PMID: 28657311]
HEK293	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay	[PMID: 25062006]
DU-145	GI₅₀	0.01 3 Compound: 1, CPT	Antiproliferative activity against human DU145 cells Antiproliferative activity against human DU145 cells	[PMID: 20155916]
HEK293	IC₅₀	0.6 3 Compound: CPT	Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32668379]
DU-145	GI₅₀	0.01 3 Compound: 1, Camptothecin	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 17676830]
HEK293	IC₅₀	0.78 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay	[PMID: 24013413]
DU-145	GI₅₀	0.01 3 Compound: 2	Growth inhibitory activity against human prostate DU-145 cell line Growth inhibitory activity against human prostate DU-145 cell line	[PMID: 15509164]
HEK293	IC₅₀	0.83 3 Compound: Camptothecin	Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HEK293	IC₅₀	0.89 3 Compound: CPT	Cytotoxicity against human HEK293 cells measured after 72 hrs by MTT assay Cytotoxicity against human HEK293 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
DU-145	GI₅₀	0.01 3 Compound: 2	Antiproliferative activity against human DU145 cell line Antiproliferative activity against human DU145 cell line	[PMID: 16913702]
DU-145	GI₅₀	0.01 3 Compound: 2	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 17696418]
HEK293	IC₅₀	1.01 3 Compound: Camptothecin	Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
HEK293	IC₅₀	1.61 3 Compound: CPT	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
DU-145	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
DU-145	GI₅₀	0.01 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human Prostate DU-145 cell line Antiproliferative activity was determined for 50% growth inhibition against human Prostate DU-145 cell line	[PMID: 11020283]
HEK293	IC₅₀	5.6 1 Compound: CPT	Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
DU-145	GI₅₀	0.01 3 Compound: Camptothecin	Concentration required to inhibit the growth of human ProstateDU-145 cells Concentration required to inhibit the growth of human ProstateDU-145 cells	[PMID: 16033260]
HEK293	IC₅₀	5.6 x 10^-4 3 Compound: CPT	Antiproliferative activity against human HEK293 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human HEK293 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
DU-145	GI₅₀	0.019 3 Compound: CPT	Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
HEK293	IC₅₀	54.69 3 Compound: Camptothecin	Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
HEK293	IC₅₀	7.94 3 Compound: CPT	Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay	[PMID: 22819942]
DU-145	GI₅₀	0.021 3 Compound: 1	Growth inhibition of human DU145 cells after 72 hrs by MTT assay Growth inhibition of human DU145 cells after 72 hrs by MTT assay	[PMID: 30336023]
HEK293	IC₅₀	8.75 3 Compound: CPT	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hr by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hr by MTT assay	[PMID: 32682183]
DU-145	GI₅₀	0.21 3 Compound: CPT	Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
DU-145	GI₅₀	0.21 3 Compound: CPT	Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
HEK-293T	IC₅₀	0.69 3 Compound: CPT	Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay	[PMID: 35612499]
HEK-293T	IC₅₀	5.65 3 Compound: CPT	Cytotoxicity against human HEK293T cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HEK293T cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
DU-145	GI₅₀	18.2 1 Compound: 1	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 24502276]
DU-145	IC₅₀	0.01 3 Compound: CPT	Antiproliferative activity against human DU145 cells by MTT assay Antiproliferative activity against human DU145 cells by MTT assay	[PMID: 17254669]
HeLa	IC₅₀	> 50 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30109008]
HeLa	GI₅₀	0.0054 3 Compound: CPT	Growth inhibition of human HeLa cells after 72 hrs by trypan blue assay Growth inhibition of human HeLa cells after 72 hrs by trypan blue assay	[PMID: 27597409]
DU-145	IC₅₀	0.015 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 96 hrs Cytotoxicity against human DU145 cells after 96 hrs	[PMID: 22276775]
DU-145	IC₅₀	0.016 3 Compound: CPT	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 30543429]
HeLa	IC₅₀	0.0089 3 Compound: 1, CPT	Cytotoxicity against human HeLa cells after 72 hrs by trypan blue assay Cytotoxicity against human HeLa cells after 72 hrs by trypan blue assay	[PMID: 21071230]
HeLa	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of HeLa cells after 4 days Growth inhibition of HeLa cells after 4 days	[PMID: 17418582]
DU-145	IC₅₀	0.02 3 Compound: Camptothecin	Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HeLa	GI₅₀	0.04 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay	[PMID: 19715319]
DU-145	IC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay	[PMID: 26945111]
DU-145	IC₅₀	0.02 3 Compound: camptothecin	Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay	[PMID: 25936262]
HeLa	GI₅₀	0.05 3 Compound: Camptothecin	Growth inhibition of human HeLa cells after 48 hrs by MTT assay Growth inhibition of human HeLa cells after 48 hrs by MTT assay	[PMID: 23357037]
HeLa	IC₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28384547]
DU-145	IC₅₀	0.0287 3 Compound: 1, CPT	Cytotoxicity against human DU145 cells by SRB assay Cytotoxicity against human DU145 cells by SRB assay	[PMID: 23102893]
HeLa	IC₅₀	0.072 3 Compound: CPT	Cytotoxicity against human HeLa cells by sulforhodamine B assay Cytotoxicity against human HeLa cells by sulforhodamine B assay	[PMID: 19345580]
DU-145	IC₅₀	0.029 3 Compound: 1, CPT	Cytotoxicity against human DU145 cells after 72 hrs by SRB assay Cytotoxicity against human DU145 cells after 72 hrs by SRB assay	[PMID: 25003995]
DU-145	IC₅₀	0.042 3 Compound: CPT	Cytotoxicity against human DU-145 cells incubated for 48 hrs by MTT assay Cytotoxicity against human DU-145 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
HeLa	GI₅₀	0.08 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20662543]
DU-145	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human DU145 cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
HeLa	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay	[PMID: 28557449]
DU-145	IC₅₀	0.07 3 Compound: 45	Anti-proliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Anti-proliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 33143937]
HeLa	IC₅₀	0.09 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28068603]
HeLa	IC₅₀	0.12 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay	[PMID: 28425292]
DU-145	IC₅₀	0.1 3 Compound: CPT	Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay	[PMID: 25799376]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay	[PMID: 25481396]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK8 assay Cytotoxicity against human DU145 cells after 2 days by CCK8 assay	[PMID: 26361737]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
DU-145	IC₅₀	0.11 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells by SRB assay Antiproliferative activity against human HeLa cells by SRB assay	[PMID: 24200393]
DU-145	IC₅₀	0.21 3 Compound: CPT	Antiproliferative activity against human DU-145 cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human DU-145 cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
HeLa	IC₅₀	0.18 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay	[PMID: 26945111]
DU-145	IC₅₀	0.31 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 21419530]
HeLa	IC₅₀	0.18 3 Compound: camptothecin	Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay	[PMID: 25936262]
DU-145	IC₅₀	0.38 3 Compound: Camptothecin	Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
HeLa	GI₅₀	0.18 3 Compound: 1, camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 18180162]
DU-145	IC₅₀	0.39 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay	[PMID: 24013413]
HeLa	IC₅₀	0.18 3 Compound: CPT	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
HeLa	IC₅₀	0.19 6 Compound: camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 18774864]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
HeLa	ED₅₀	0.19 6 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 18220355]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 21601964]
HeLa	GI₅₀	0.19 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
DU-145	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
HeLa	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay	[PMID: 19715319]
DU-145	IC₅₀	0.61 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 21115246]
HeLa	IC₅₀	0.23 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human HeLa cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
DU-145	IC₅₀	0.61 3 Compound: Camptothecin	Antiproliferative activity against human DU-145 cells incubated for 72 hrs by microplate reader analysis Antiproliferative activity against human DU-145 cells incubated for 72 hrs by microplate reader analysis	[PMID: 37418826]
HeLa	IC₅₀	0.28 6 Compound: Camptothecin	Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay	10.1007/s00044-010-9381-7
DU-145	IC₅₀	0.66 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay	[PMID: 19939682]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay	[PMID: 25481396]
DU-145	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
DU-145	IC₅₀	0.94 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells in presence of 10% fetal bovine serum Cytotoxicity against human DU145 cells in presence of 10% fetal bovine serum	[PMID: 20188578]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HeLa	IC₅₀	0.4 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTS assay Cytotoxicity against human HeLa cells after 48 hrs by MTS assay	[PMID: 23153813]
DU-145	IC₅₀	0.95 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay	[PMID: 25062006]
DU-145	IC₅₀	1 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 19836231]
HeLa	IC₅₀	0.4 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTS assay Cytotoxicity against human HeLa cells after 48 hrs by MTS assay	[PMID: 22542106]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 21601964]
DU-145	IC₅₀	1.06 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
DU-145	IC₅₀	1.46 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 3 days Cytotoxicity against human DU145 cells after 3 days	[PMID: 19954977]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
DU-145	IC₅₀	1.99 3 Compound: Camptothecin	Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
HeLa	IC₅₀	0.41 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
HeLa	IC₅₀	0.42 3 Compound: CPT, Camptothecin	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24980118]
DU-145	IC₅₀	2.37 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 22318164]
DU-145	IC₅₀	3.2 3 Compound: Camptothecin	Cytotoxicity against human DU145 cells after 4 days by MTT assay Cytotoxicity against human DU145 cells after 4 days by MTT assay	[PMID: 20619511]
HeLa	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 24 to 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
HeLa	IC₅₀	0.5 3 Compound: camptothecine	Cytotoxicity against human HeLa cells by MTT method Cytotoxicity against human HeLa cells by MTT method	[PMID: 17547457]
DU-145	IC₅₀	3.2 3 Compound: camptothecin	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 18178085]
DU-145	IC₅₀	3.57 3 Compound: camptothecin	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 20093033]
HeLa	IC₅₀	0.5 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human HeLa cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
DU-145	IC₅₀	33.45 1 Compound: CPT	Cytotoxicity against human DU-145 cells assessed as inhibition of cell growth Cytotoxicity against human DU-145 cells assessed as inhibition of cell growth	[PMID: 37806498]
HeLa	IC₅₀	0.58 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 19836231]
HeLa	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 3 days by CCK8 assay Cytotoxicity against human HeLa cells after 3 days by CCK8 assay	[PMID: 26927425]
DU-145	IC₅₀	4.01 3 Compound: CPT	Cytotoxicity against human DU145 cells after 2 days Cytotoxicity against human DU145 cells after 2 days	[PMID: 24904965]
HeLa	GI₅₀	0.6 3 Compound: Camptothecin	Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay	[PMID: 15026047]
DU-145	IC₅₀	9.29 3 Compound: CPT	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 22819942]
HeLa	GI₅₀	0.6 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay	[PMID: 23831507]
HeLa	IC₅₀	0.63 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay	[PMID: 19939682]
Daudi	IC₅₀	118.9 3 Compound: CPT	Antiproliferative activity against human Daudi cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against human Daudi cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
HeLa	IC₅₀	0.66 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30125725]
Detroit 551	GI₅₀	0.99 3 Compound: CPT	Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay	[PMID: 20591678]
HeLa	IC₅₀	0.86 3 Compound: camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20093033]
Detroit 551	GI₅₀	0.99 3 Compound: CPT	Cytotoxicity against human Detroit 551 cells after 48 hrs by MTT assay Cytotoxicity against human Detroit 551 cells after 48 hrs by MTT assay	[PMID: 20662543]
Detroit 551	IC₅₀	0.99 3 Compound: CPT	Antiproliferative activity against human Detroit 551 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human Detroit 551 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
HeLa	IC₅₀	0.94 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 20356735]
HeLa	IC₅₀	0.94 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 24 hrs by crystal violet staining-based assay Antiproliferative activity against human HeLa cells after 24 hrs by crystal violet staining-based assay	[PMID: 29407986]
HeLa	IC₅₀	1.01 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 22318164]
Erythrocyte	EC₅₀	429.9 6 Compound: Camptothecin	Hemolytic activity in Homo sapiens (human) Erythrocyte after 30 min Hemolytic activity in Homo sapiens (human) Erythrocyte after 30 min	10.1007/s00044-010-9381-7
HeLa	IC₅₀	1.08 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 21419530]
Fibroblast	IC₅₀	459.3 1 Compound: camptothecin	Cytotoxicity against human Fibroblasts by SRB assay Cytotoxicity against human Fibroblasts by SRB assay	[PMID: 21410162]
HeLa	IC₅₀	1.1 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 4 days by MTT assay Cytotoxicity against human HeLa cells after 4 days by MTT assay	[PMID: 20619511]
HeLa	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human HeLa cells by SRB staining-based fluorescence cytometry Cytotoxicity against human HeLa cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
H22	IC₅₀	0.54 3 Compound: 1; CPT	Antiproliferative activity against mouse H22 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against mouse H22 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
H69AR	IC₅₀	> 300 1 Compound: 1a	Cytotoxicity against human H69AR cells overexpressing MDR1 after 72 hrs by alamar blue assay Cytotoxicity against human H69AR cells overexpressing MDR1 after 72 hrs by alamar blue assay	[PMID: 21341674]
HeLa	GI₅₀	1.3 3 Compound: 1	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21388138]
HBL-100	GI₅₀	0.2 3 Compound: Camptothecin	Antiproliferative activity against human HBL-100 cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay Antiproliferative activity against human HBL-100 cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay	[PMID: 37531922]
HeLa	IC₅₀	1.3 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 30007563]
HBL-100	GI₅₀	0.23 3 Compound: CPT	Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HeLa	GI₅₀	1.3 3 Compound: CPT	Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HBL-100	GI₅₀	0.23 3 Compound: Camptothecin	Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay	[PMID: 23831507]
HeLa	IC₅₀	1.37 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
HeLa	IC₅₀	1.37 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
HCC70	IC₅₀	0.044 3 Compound: Camptothecin	Antiproliferative activity against human HCC70 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human HCC70 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
HeLa	IC₅₀	1.41 3 Compound: 1; CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 27416553]
HCCLM9	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HCCLM9 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HCCLM9 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HeLa	IC₅₀	1.5 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21186067]
HeLa	IC₅₀	1.57 3 Compound: CPT	Cytotoxicity against human HeLa cells after 24 hrs by MTS assay Cytotoxicity against human HeLa cells after 24 hrs by MTS assay	[PMID: 23153813]
HeLa	IC₅₀	1.57 3 Compound: CPT	Cytotoxicity against human HeLa cells after 24 hrs by MTS assay Cytotoxicity against human HeLa cells after 24 hrs by MTS assay	[PMID: 22542106]
HeLa	IC₅₀	1.59 3 Compound: CPT	Cytotoxicity against human HeLa cells measured after 2 days by MTT assay Cytotoxicity against human HeLa cells measured after 2 days by MTT assay	[PMID: 26334499]
HeLa	IC₅₀	1.85 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 3 days Cytotoxicity against human HeLa cells after 3 days	[PMID: 19954977]
HeLa	IC₅₀	10.1 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28462840]
HeLa	IC₅₀	11.36 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as decrease in cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell proliferation after 48 hrs by MTT assay	[PMID: 27667553]
HeLa	IC₅₀	11.62 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25599951]
HeLa	IC₅₀	14 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 26188908]
HeLa	IC₅₀	19.8 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
HeLa	IC₅₀	2.62 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28633898]
HeLa	IC₅₀	24 1 Compound: CPT	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 24900725]
HeLa	IC₅₀	3.8 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28511910]
HeLa	IC₅₀	59.13 3 Compound: Camptothecin	Growth inhibition of human HeLa cells after 72 hrs by MTT assay Growth inhibition of human HeLa cells after 72 hrs by MTT assay	[PMID: 27344492]
HeLa	IC₅₀	6 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
HeLa	IC₅₀	6.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay	[PMID: 26602827]
HeLa	IC₅₀	6.51 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30685528]
HeLa	IC₅₀	60.01 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
HeLa	IC₅₀	8.28 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
HCT-116	EC₅₀	3.15 1 Compound: 1; CPT	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 38421819]
HeLa	IC₅₀	8.93 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay	[PMID: 21983445]
Hep 3B2	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HCT-116	GI₅₀	0.009 3 Compound: 1	Growth inhibition of human HCT116 cells after 72 hrs by MTT assay Growth inhibition of human HCT116 cells after 72 hrs by MTT assay	[PMID: 30336023]
Hep 3B2	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay	[PMID: 19715319]
HCT-116	GI₅₀	0.009 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
Hep 3B2	IC₅₀	0.06 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay	[PMID: 19715319]
HCT-116	GI₅₀	0.009 3 Compound: CPT	Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
HEp-2	IC₅₀	0.02 6 Compound: camptothecin	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 18774864]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cell line Antiproliferative activity against human HCT116 cell line	[PMID: 16442283]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 17402722]
HEp-2	ED₅₀	0.02 6 Compound: Camptothecin	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 18220355]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells Antiproliferative activity against human HCT116 cells	[PMID: 18630891]
HEp-2	IC₅₀	0.7 3 Compound: Camptothecin	Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HEp-2	IC₅₀	3.01 3 Compound: CPT	Cytotoxicity against against human Hep2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human Hep2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 19783447]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 20630766]
HEp-2	IC₅₀	3.04 3 Compound: CPT	Cytotoxicity against human Hep2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human Hep2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
HEp-2	IC₅₀	3.04 3 Compound: CPT	Cytotoxicity against human Hep2 cells measured after 72 hrs by MTT assay Cytotoxicity against human Hep2 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells by SRB assay Antiproliferative activity against human HCT116 cells by SRB assay	[PMID: 21710981]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay	[PMID: 21823606]
HepG2	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 22409771]
HepG2	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HCT-116	GI₅₀	0.03 3 Compound: 1	Cytotoxicity against human HCT116 cells by SRB assay Cytotoxicity against human HCT116 cells by SRB assay	[PMID: 24502276]
HCT-116	GI₅₀	0.03 3 Compound: 1	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 24800942]
HepG2	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HepG2	IC₅₀	0.01 3 Compound: CPT	Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells after 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs	[PMID: 27070999]
HCT-116	GI₅₀	0.03 3 Compound: 1	Antiproliferative activity against human HCT116 cells assessed as growth inhibition Antiproliferative activity against human HCT116 cells assessed as growth inhibition	[PMID: 28657311]
HepG2	CC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22047799]
HepG2	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 36924947]
HCT-116	GI₅₀	0.03 3 Compound: 1, CPT	Antiproliferative activity against human HCT116 cells Antiproliferative activity against human HCT116 cells	[PMID: 20155916]
HepG2	IC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs Cytotoxicity against human HepG2 cells after 96 hrs	[PMID: 22276775]
HCT-116	GI₅₀	0.03 3 Compound: 1, Camptothecin	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 17676830]
HCT-116	GI₅₀	0.03 3 Compound: 2	Growth inhibitory activity against human colon HCT116 cell line Growth inhibitory activity against human colon HCT116 cell line	[PMID: 15509164]
HepG2	IC₅₀	0.03 3 Compound: CPT	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 17254669]
HepG2	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HCT-116	GI₅₀	0.03 3 Compound: 2	Antiproliferative activity against human HCT116 cell line Antiproliferative activity against human HCT116 cell line	[PMID: 16913702]
HCT-116	GI₅₀	0.03 3 Compound: 2	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 17696418]
HepG2	CC₅₀	0.04 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22884523]
HepG2	IC₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24360564]
HCT-116	GI₅₀	0.03 3 Compound: 2	Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
HepG2	IC₅₀	0.06 3 Compound: camptothecin	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 19863101]
HCT-116	GI₅₀	0.03 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human colon HCT116 cell line Antiproliferative activity was determined for 50% growth inhibition against human colon HCT116 cell line	[PMID: 11020283]
HCT-116	GI₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
HepG2	GI₅₀	0.1 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
HCT-116	GI₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HepG2	IC₅₀	0.11 3 Compound: 1; CPT	Antiproliferative activity against human HepG2 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HCT-116	GI₅₀	0.075 3 Compound: 1	Growth inhibition of human HCT116 cells expressing TOP1 siRNA after 72 hrs by MTT assay Growth inhibition of human HCT116 cells expressing TOP1 siRNA after 72 hrs by MTT assay	[PMID: 30336023]
HepG2	IC₅₀	0.13 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells after 4 days by MTT assay Cytotoxicity against human HepG2 cells after 4 days by MTT assay	[PMID: 18554906]
HepG2	IC₅₀	0.2 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
HCT-116	GI₅₀	0.075 3 Compound: CPT	Cytotoxicity against human HCT116 cells expressing TOP1 siRNA assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells expressing TOP1 siRNA assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
HCT-116	GI₅₀	0.075 3 Compound: CPT	Growth inhibition of human HCT116 cells expressing siTOP1 incubated for 72 hrs by MTT assay Growth inhibition of human HCT116 cells expressing siTOP1 incubated for 72 hrs by MTT assay	[PMID: 31176097]
HepG2	IC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24041234]
HepG2	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
HCT-116	GI₅₀	0.083 3 Compound: 1, CPT	Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HepG2	GI₅₀	0.22 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HCT-116	GI₅₀	0.195 3 Compound: Camptothecin	Antiproliferative activity against human HCT-116 p53-/- cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HCT-116 p53-/- cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HCT-116	GI₅₀	17.38 1 Compound: 1	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24502276]
HepG2	IC₅₀	0.3 3 Compound: camptothecin	Cytotoxicity against human HEPG2 cells by MTT assay Cytotoxicity against human HEPG2 cells by MTT assay	[PMID: 18841903]
HCT-116	GI₅₀	3.86 14 Compound: 1; CPT	Growth inhibition of human HCT-116 cells incubated for 72 hrs by MTT assay Growth inhibition of human HCT-116 cells incubated for 72 hrs by MTT assay	[PMID: 38421819]
HepG2	IC₅₀	0.37 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30055465]
HCT-116	GI₅₀	35.48 1 Compound: 1	Cytotoxicity against human HCT116 cells transfected with Top1-siRNA after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells transfected with Top1-siRNA after 72 hrs by MTT assay	[PMID: 24502276]
HepG2	IC₅₀	0.4 3 Compound: CPT	Antitumor activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
HepG2	IC₅₀	0.43 3 Compound: Camp	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
HCT-116	IC₅₀	0.00015 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 25247770]
HCT-116	IC₅₀	0.003 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
HepG2	IC₅₀	0.5 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 30007563]
HepG2	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
HCT-116	IC₅₀	0.009 3 Compound: CPT	Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
HCT-116	IC₅₀	0.009 3 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by MTS method Cytotoxicity against human HCT116 cells after 72 hrs by MTS method	[PMID: 11858737]
HepG2	IC₅₀	0.66 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30600208]
HCT-116	IC₅₀	0.011 3 Compound: CPT	Cytotoxicity against human HCT-116 cells measured after 72 hrs Cytotoxicity against human HCT-116 cells measured after 72 hrs	[PMID: 38716896]
HepG2	IC₅₀	1.36 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30125725]
HCT-116	IC₅₀	0.0115 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28454671]
HepG2	IC₅₀	1.52 3 Compound: 1; CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27416553]
HCT-116	IC₅₀	0.013 3 Compound: CPT	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 30543429]
HepG2	IC₅₀	13.2 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
HepG2	IC₅₀	29.81 3 Compound: Camptothecin	Growth inhibition of human HepG2 cells after 72 hrs by MTT assay Growth inhibition of human HepG2 cells after 72 hrs by MTT assay	[PMID: 27344492]
HCT-116	IC₅₀	0.016 3 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by WST-8 assay Cytotoxicity against human HCT116 cells after 72 hrs by WST-8 assay	[PMID: 24033077]
HepG2	IC₅₀	3.5 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
HCT-116	IC₅₀	0.017 3 Compound: CPT	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
HepG2	IC₅₀	32.3 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 23562244]
HCT-116	IC₅₀	0.02 3 Compound: CPT	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
HepG2	IC₅₀	4.37 3 Compound: Camp	Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
HCT-116	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
HCT-116	IC₅₀	0.04 3 Compound: CPT	In-vitro antitumor activity against human HCT-116 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human HCT-116 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
HepG2	IC₅₀	4.79 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30685528]
HepG2	IC₅₀	4.92 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28511910]
HCT-116	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human HCT-116 cells Cytotoxicity against human HCT-116 cells	[PMID: 36924947]
HCT-116	IC₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HCT-116 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HepG2	IC₅₀	455 1 Compound: camptothecin	Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay	[PMID: 19655762]
HepG2	IC₅₀	5.69 3 Compound: CPT	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
HCT-116	IC₅₀	0.051 3 Compound: CPT	Cytotoxicity against human HCT-116 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
HCT-116	IC₅₀	0.07 3 Compound: 1, CPT	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24069881]
HepG2	IC₅₀	6.08 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30125725]
HCT-116	IC₅₀	0.09 3 Compound: 1; CPT	Antiproliferative activity against human HCT-116 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HepG2	IC₅₀	6.4 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 22326393]
HFL1	IC₅₀	1.06 3 Compound: Camptothecin	Antiproliferative activity against HFL1 cells after 72 hrs by CCK8 assay Antiproliferative activity against HFL1 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HCT-116	IC₅₀	0.09 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 26226379]
HCT-116	IC₅₀	0.11 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 3 days by MTT assay Antiproliferative activity against human HCT116 cells after 3 days by MTT assay	[PMID: 23084702]
HGC-27	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HGC-27 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HGC-27	IC₅₀	0.166 3 Compound: CPT	Antiproliferative activity against human HGC-27 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
HCT-116	IC₅₀	0.12 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 28351590]
HL-60	GI₅₀	< 0.003 3 Compound: 1, CPT	Cytotoxicity against human HL60 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HL60 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HCT-116	IC₅₀	0.13 3 Compound: CPT	Antiproliferative activity against human HCT116 cells after 3 days by XTT assay Antiproliferative activity against human HCT116 cells after 3 days by XTT assay	[PMID: 19691293]
HL-60	IC₅₀	< 0.064 3 Compound: CPT; 1	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 30509782]
HCT-116	IC₅₀	0.159 3 Compound: Camptothecin	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 27318980]
HCT-116	IC₅₀	0.159 3 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay	[PMID: 28477443]
HL-60	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 26188908]
HL-60	IC₅₀	0.017 3 Compound: 1, CPT	Cytotoxicity against human HL60 cells after 72 hrs by trypan blue assay Cytotoxicity against human HL60 cells after 72 hrs by trypan blue assay	[PMID: 21071230]
HCT-116	IC₅₀	0.21 3 Compound: CPT	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
HCT-116	IC₅₀	0.25 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 33158579]
HL-60	IC₅₀	0.018 3 Compound: Camptothecin	Antiproliferation activity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Antiproliferation activity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32201190]
HL-60	IC₅₀	0.018 3 Compound: CPT	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 21353568]
HCT-116	IC₅₀	0.4 3 Compound: CPT	Antitumor activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
HL-60	IC₅₀	0.018 3 Compound: camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 17498951]
HCT-116	IC₅₀	0.6 3 Compound: CPT	Cytotoxicity against human HCT-116 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
HL-60	IC₅₀	0.019 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells measured after 48 hrs by WST1 assay Antiproliferative activity against human HL60 cells measured after 48 hrs by WST1 assay	[PMID: 28477443]
HCT-116	IC₅₀	1 3 Compound: camptothecin	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 18178085]
HL-60	IC₅₀	0.019 3 Compound: Camptothecin	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by WST-1 assay Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by WST-1 assay	[PMID: 27318980]
HCT-116	IC₅₀	1.88 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
HCT-116	IC₅₀	1.88 3 Compound: CPT	Cytotoxicity against against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
HL-60	IC₅₀	0.02 3 Compound: Camp	Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
HCT-116	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 19655762]
HL-60	GI₅₀	0.03 3 Compound: camptothecin	Growth inhibition of human HL60 cells by Almar blue assay Growth inhibition of human HL60 cells by Almar blue assay	[PMID: 17418582]
HL-60	IC₅₀	0.035 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
HCT-116	IC₅₀	2.01 1 Compound: 1; CPT	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 38421819]
HL-60	IC₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 24041234]
HCT-116	IC₅₀	2.01 1 Compound: Camptothecin	Cytotoxicity against human HCT-116 cells assessed as cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell viability incubated for 24 hrs by MTT assay	[PMID: 35567964]
HL-60	IC₅₀	0.065 3 Compound: camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 20093033]
HCT-116	IC₅₀	2.01 14 Compound: 1; CPT	Cytotoxicity against human HCT-116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 38421819]
HCT-116	IC₅₀	2.3 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 4 days by MTT assay Cytotoxicity against human HCT116 cells after 4 days by MTT assay	[PMID: 20619511]
HL-60	IC₅₀	0.065 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days Cytotoxicity against human HL60 cells after 2 days	[PMID: 21419530]
HCT-116	IC₅₀	2.77 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 3 days Cytotoxicity against human HCT116 cells after 3 days	[PMID: 19954977]
HL-60	IC₅₀	0.067 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 19836231]
HCT-116	IC₅₀	22.9 1 Compound: 1, CPT	Cytotoxicity against human HCT116 after 72 hrs by SRB assay Cytotoxicity against human HCT116 after 72 hrs by SRB assay	[PMID: 22647222]
HL-60	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 25599951]
HCT-116	IC₅₀	3.97 3 Compound: Camptothecin	Cytotoxicity against human HCT116 cells after 2 days Cytotoxicity against human HCT116 cells after 2 days	[PMID: 21419530]
HL-60	IC₅₀	0.07 3 Compound: Camp	Induction of apoptosis in human HL60 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human HL60 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
HL-60	IC₅₀	0.089 3 Compound: CPT	Cytotoxicity against human HL60 cells by sulforhodamine B assay Cytotoxicity against human HL60 cells by sulforhodamine B assay	[PMID: 19345580]
HCT-116	IC₅₀	4.75 3 Compound: Camptothecin	Inhibition of DNA topoisomerase 1 in Homo sapiens (human) HCT116 cells Inhibition of DNA topoisomerase 1 in Homo sapiens (human) HCT116 cells	10.1007/s00044-009-9233-5
HL-60	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days Cytotoxicity against human HL60 cells after 2 days	[PMID: 21601964]
HCT-116	IC₅₀	6.7 3 Compound: CPT	Cytotoxicity against human HCT116 cells measured after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
HL-60	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
HCT-116	IC₅₀	8.5 1 Compound: Camptothecin	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay	[PMID: 32952994]
HCT-116	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 3 days by SRB assay Cytotoxicity against human HCT116 cells after 3 days by SRB assay	[PMID: 23142674]
HL-60	IC₅₀	0.42 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 30109008]
HCT-116	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 22409771]
HL-60	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 20356735]
HCT-116	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HL-60	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days by MTT assay Cytotoxicity against human HL60 cells after 2 days by MTT assay	[PMID: 22325897]
HCT-116	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HL-60	IC₅₀	0.68 3 Compound: 1	Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells	[PMID: 8410981]
HL-60	IC₅₀	0.8 3 Compound: camptothecin	Cytotoxicity against human HL60 cells by rapid colorimetric assay Cytotoxicity against human HL60 cells by rapid colorimetric assay	[PMID: 19585998]
HCT-116	IC₅₀	<= 0.1 3 Compound: CPT	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HL-60	IC₅₀	0.91 3 Compound: Camptothecin	Antitumor activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
HL-60	IC₅₀	0.92 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method	[PMID: 29131616]
HL-60	GI₅₀	1.7 1 Compound: CPT, camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 17962028]
HL-60	IC₅₀	1.7 3 Compound: Camptothecin	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 33161122]
HL-60	IC₅₀	130 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 15974606]
HCT-15	IC₅₀	0.0014 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
HL-60	IC₅₀	6 1 Compound: camptothecin	Cytotoxicity against human HL60 cells after 72 hrs by MTS assay Cytotoxicity against human HL60 cells after 72 hrs by MTS assay	[PMID: 19655762]
HCT-15	IC₅₀	0.02 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
HL60/MX2	GI₅₀	1.5 1 Compound: CPT, camptothecin	Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay	[PMID: 17962028]
HCT-15	IC₅₀	0.049 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human HCT15 cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
HOC-21 cell line	IC₅₀	14.7 14 Compound: 1a	Tested in vitro for the inhibition of HOC-21(human ovarian cancer) cell line by MTT assay Tested in vitro for the inhibition of HOC-21(human ovarian cancer) cell line by MTT assay	[PMID: 7932525]
HCT-15	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
HCT-15	IC₅₀	0.05 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
HOP-62	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay	[PMID: 28418653]
HCT-15	IC₅₀	0.067 3 Compound: Camptothecin	Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HOP-62	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human HOP62 cells after 48 hrs by SRB assay Growth inhibition of human HOP62 cells after 48 hrs by SRB assay	[PMID: 24800942]
HCT-15	IC₅₀	0.08 3 Compound: CPT	Antiproliferative activity against human HCT-15 cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human HCT-15 cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay	[PMID: 21823606]
HCT-15	IC₅₀	0.08 3 Compound: CPT, campothecin	Cytotoxicity against human HCT15 cells by SRB assay Cytotoxicity against human HCT15 cells by SRB assay	[PMID: 17827007]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells by SRB assay Cytotoxicity against human HOP62 cells by SRB assay	[PMID: 24502276]
HCT-15	IC₅₀	0.083 3 Compound: camptothecin	Cytotoxicity against human HCT15 cells after 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs	[PMID: 17673337]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells by SRB assay Antiproliferative activity against human HOP62 cells by SRB assay	[PMID: 21710981]
HCT-15	IC₅₀	0.096 6 Compound: CPT	Cytotoxicity against human HCT15 cells by sulforhodamine B assay Cytotoxicity against human HCT15 cells by sulforhodamine B assay	[PMID: 21684168]
HOP-62	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells after 48 hrs Antiproliferative activity against human HOP62 cells after 48 hrs	[PMID: 27070999]
HCT-15	IC₅₀	0.166 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay	[PMID: 21873069]
Hs 683	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human Hs683 cells after 72 hrs by MTT assay Growth inhibition of human Hs683 cells after 72 hrs by MTT assay	[PMID: 24180210]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 22318164]
HT-1080	IC₅₀	0.08 3 Compound: CPT	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 21353568]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay	[PMID: 25481396]
HT-1080	IC₅₀	0.08 3 Compound: camptothecin	Cytotoxicity against human HT1080 cells by SRB assay Cytotoxicity against human HT1080 cells by SRB assay	[PMID: 17498951]
HCT-15	IC₅₀	0.26 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28384547]
HT-29	IC₅₀	> 100 3 Compound: CPT	Cytotoxicity against human HT-29 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HCT-15	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay	[PMID: 26361737]
HCT-15	IC₅₀	0.31 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HT-29	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HT-29	IC₅₀	0.014 3 Compound: camptothecin	Growth inhibition of human HT29 cells by neutral red assay Growth inhibition of human HT29 cells by neutral red assay	[PMID: 17204425]
HCT-15	IC₅₀	0.35 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
HT-29	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
HCT-15	IC₅₀	0.42 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay	[PMID: 24013413]
HT-29	GI₅₀	0.03 3 Compound: 1, CPT	Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
HCT-15	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
HT-29	GI₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 23831811]
HCT-15	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 21601964]
HCT-15	IC₅₀	0.52 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
HT-29	GI₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 21115210]
HCT-15	IC₅₀	0.6 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28068603]
HT-29	IC₅₀	0.06 3 Compound: CPT	Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 24360564]
HCT-15	IC₅₀	0.64 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells in presence of 10% fetal bovine serum Cytotoxicity against human HCT15 cells in presence of 10% fetal bovine serum	[PMID: 20188578]
HT-29	ED₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay	[PMID: 20939540]
HCT-15	IC₅₀	0.76 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay	[PMID: 19939682]
HT-29	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 36924947]
HCT-15	IC₅₀	0.76 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 28633898]
HT-29	IC₅₀	0.0878 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of HT 29 cell population by 50%. Inhibitory concentration that reduced the viability of HT 29 cell population by 50%.	[PMID: 9003520]
HT-29	IC₅₀	0.09 3 Compound: 1, CPT	Cytotoxicity against human HT29 cells after 4 days by MTT assay Cytotoxicity against human HT29 cells after 4 days by MTT assay	[PMID: 18554906]
HCT-15	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells by MTT assay Cytotoxicity against human HCT15 cells by MTT assay	[PMID: 21115246]
HT-29	IC₅₀	0.12 3 Compound: 1, CPT	Antitumor activity against human HT-29 cells by SRB method Antitumor activity against human HT-29 cells by SRB method	[PMID: 19541483]
HCT-15	IC₅₀	1.29 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay	[PMID: 26927425]
HT-29	IC₅₀	0.4 3 Compound: 1, CPT	Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
HCT-15	IC₅₀	1.38 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
HT-29	IC₅₀	0.7 1 Compound: Camptothecin	Antiproliferative activity against human HT-29 cells by SRB assay Antiproliferative activity against human HT-29 cells by SRB assay	[PMID: 24200393]
HCT-15	IC₅₀	1.59 3 Compound: Camptothecin	Antiproliferative activity against human HCT-15 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human HCT-15 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
HT-29	IC₅₀	0.85 3 Compound: camptothecin	Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 20093033]
HCT-15	IC₅₀	1.98 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay	[PMID: 25062006]
HT-29	IC₅₀	1.07 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 19836231]
HCT-15	IC₅₀	10.07 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 2 days Cytotoxicity against human HCT15 cells after 2 days	[PMID: 24904965]
HT-29	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human HT-29 cells by SRB staining-based fluorescence cytometry Cytotoxicity against human HT-29 cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
HCT-15	IC₅₀	18 1 Compound: camptothecin	Antiproliferative activity against human HCT15 cell line Antiproliferative activity against human HCT15 cell line	[PMID: 16686539]
HT-29	IC₅₀	1.37 3 Compound: CPT	Antiproliferative activity against human HT-29 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
HCT-15	IC₅₀	2.82 3 Compound: Camptothecin	Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay	[PMID: 26945111]
HCT-15	IC₅₀	2.82 3 Compound: camptothecin	Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay	[PMID: 25936262]
HT-29	IC₅₀	1.4 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line aws determined by SRB assay In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line aws determined by SRB assay	[PMID: 12639541]
HCT-15	IC₅₀	3 1 Compound: camptothecin	Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay	[PMID: 19655762]
HT-29	IC₅₀	10 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 21843907]
HT-29	IC₅₀	2 3 Compound: camptothecin	Cytotoxicity against human HT29 cells by MTT assay Cytotoxicity against human HT29 cells by MTT assay	[PMID: 18841903]
HCT-15	IC₅₀	6.08 3 Compound: CPT	Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay	[PMID: 26334499]
HCT-15	IC₅₀	7.1 3 Compound: Camptothecin	Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay	[PMID: 26988802]
HT-29	IC₅₀	260 1 Compound: 1a	Cytotoxicity against human HT-29 cells after 72 hrs by alamar blue assay Cytotoxicity against human HT-29 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HCT-15	IC₅₀	9.92 3 Compound: CPT	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 22819942]
HT-29	IC₅₀	3.16 3 Compound: 1, CPT	Cytotoxicity against human HT29 cells after 1 hr Cytotoxicity against human HT29 cells after 1 hr	[PMID: 18419110]
HCT-8	IC₅₀	0.007 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against HCT-8 (human colon cancer) In vitro cytotoxicity against HCT-8 (human colon cancer)	[PMID: 14552770]
HT-29	IC₅₀	3.16 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against human HT29 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against human HT29 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
HT-29	IC₅₀	46 1 Compound: 1	Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay	[PMID: 7853331]
HCT-8	IC₅₀	0.024 3 Compound: 1; CPT	Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 27871039]
HCT-8	IC₅₀	0.26 3 Compound: Camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 22044245]
HT-29	IC₅₀	8.81 3 Compound: 1, CPT	Cytotoxicity against human mitoxantrone-resistant HT29 cells after 1 hr Cytotoxicity against human mitoxantrone-resistant HT29 cells after 1 hr	[PMID: 18419110]
HCT-8	IC₅₀	3.15 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 18095653]
HT-29	IC₅₀	8.81 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against BCRP overexpressing mitoxantrone-resistant human HT29 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against BCRP overexpressing mitoxantrone-resistant human HT29 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
HT-29	IC₅₀	80 1 Compound: CPT	Cytotoxicity against HT-29 tumor cell line determined by WST-1 assay Cytotoxicity against HT-29 tumor cell line determined by WST-1 assay	[PMID: 10841808]
HCT-8	IC₅₀	3.2 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 19256478]
HCT-8	IC₅₀	3.6 3 Compound: camptothecin	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 25237727]
Huh-7	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 22409771]
HCT-8	IC₅₀	< 0.005 6 Compound: 1 Camptothecin	In vitro cytotoxicity against HCT-8 cell line (human colon cancer) using MTT assay In vitro cytotoxicity against HCT-8 cell line (human colon cancer) using MTT assay	[PMID: 15225719]
Huh-7	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human Huh-7 cells measured after 72 hrs by MTT assay Antiproliferative activity against human Huh-7 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
Huh-7	IC₅₀	≤ 0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HCT-8	IC₅₀	< 0.013 3 Compound: CPT	Cytotoxicity against human HCT8 cells after 3 days by MTT assay Cytotoxicity against human HCT8 cells after 3 days by MTT assay	[PMID: 20392545]
HEK-293T	IC₅₀	0.03 3 Compound: CPT	Cytotoxicity against HEK293T cells Cytotoxicity against HEK293T cells	[PMID: 36924947]
Huh-7	IC₅₀	0.0023 3 Compound: CPT	Cytotoxicity against human HuH7 cells by MTT assay Cytotoxicity against human HuH7 cells by MTT assay	[PMID: 30543429]
HEK-293T	IC₅₀	0.69 3 Compound: CPT	Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay	[PMID: 35612499]
Huh-7	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 25247770]
HEK-293T	IC₅₀	5.65 3 Compound: CPT	Cytotoxicity against human HEK293T cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HEK293T cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
Huh-7	GI₅₀	0.006 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
Huh-7	IC₅₀	0.06 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 3 days by SRB assay Cytotoxicity against human HuH7 cells after 3 days by SRB assay	[PMID: 23142674]
HEK293	IC₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay Cytotoxicity against HEK293 cells measured after 48 hrs by MTT assay	[PMID: 28027871]
HEK293	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay	[PMID: 25062006]
Huh-7	GI₅₀	0.099 3 Compound: 1	Growth inhibition of human HuH7 cells after 72 hrs by MTT assay Growth inhibition of human HuH7 cells after 72 hrs by MTT assay	[PMID: 30336023]
HEK293	IC₅₀	0.6 3 Compound: CPT	Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32668379]
Huh-7	IC₅₀	0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay	10.1039/C4MD00306C
Huh-7	IC₅₀	0.15 3 Compound: CPT	Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HEK293	IC₅₀	0.78 3 Compound: Camptothecin	Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay	[PMID: 24013413]
Huh-7	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human HuH7 cells after 48 hrs by CCK8 assay Cytotoxicity against human HuH7 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
HEK293	IC₅₀	0.81 3 Compound: CPT	Antiproliferative activity against human HEK293 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human HEK293 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
HUVEC	IC₅₀	0.01 3 Compound: CPT	Cytotoxicity against human HUVEC cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HUVEC cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HEK293	IC₅₀	0.83 3 Compound: Camptothecin	Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
HEK293	IC₅₀	0.89 3 Compound: CPT	Cytotoxicity against human HEK293 cells measured after 72 hrs by MTT assay Cytotoxicity against human HEK293 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
HUVEC	IC₅₀	0.012 3 Compound: CPT	In-vitro cytotoxic activity against human HUVEC cells incubated for 72 hrs by CCK8 assay In-vitro cytotoxic activity against human HUVEC cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
HEK293	IC₅₀	1.01 3 Compound: Camptothecin	Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
HUVEC	IC₅₀	0.2 3 Compound: Camptothecin	Toxicity against HUVEC incubated for 48 hrs by MTT assay Toxicity against HUVEC incubated for 48 hrs by MTT assay	[PMID: 25590864]
IGROV-1	IC₅₀	0.012 3 Compound: 1, CPT	Cytotoxicity against human IGROV1 cells after 72 hrs Cytotoxicity against human IGROV1 cells after 72 hrs	[PMID: 18419110]
HEK293	IC₅₀	1.61 3 Compound: CPT	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
HEK293	IC₅₀	5.6 1 Compound: CPT	Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
IGROV-1	IC₅₀	1.65 3 Compound: 1, CPT	Cytotoxicity against human IGROV1 cells after 1 hr Cytotoxicity against human IGROV1 cells after 1 hr	[PMID: 18419110]
HEK293	IC₅₀	5.6 x 10^-4 3 Compound: CPT	Antiproliferative activity against human HEK293 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human HEK293 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
IMR-32	IC₅₀	0.08 3 Compound: Camptothecin	Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
IMR-90	IC₅₀	0.43 3 Compound: Camptothecin	Cytotoxicity against human IMR90 cells incubated for 3 days by SRB assay Cytotoxicity against human IMR90 cells incubated for 3 days by SRB assay	[PMID: 22863526]
HEK293	IC₅₀	54.69 3 Compound: Camptothecin	Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
HEK293	IC₅₀	7.94 3 Compound: CPT	Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay	[PMID: 22819942]
Jurkat	IC₅₀	0.026 3 Compound: Camptothecin	Cytotoxicity against human Jurkat cells after 2 days by MTT assay Cytotoxicity against human Jurkat cells after 2 days by MTT assay	[PMID: 22325897]
HEK293	IC₅₀	8.75 3 Compound: CPT	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hr by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hr by MTT assay	[PMID: 32682183]
Jurkat	GI₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
Jurkat	IC₅₀	0.085 3 Compound: CPT	Anticancer activity against human Jurkat cells after 48 hrs by MTT assay Anticancer activity against human Jurkat cells after 48 hrs by MTT assay	[PMID: 26890120]
HEp-2	ED₅₀	0.02 6 Compound: Camptothecin	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 18220355]
HEp-2	IC₅₀	0.02 6 Compound: camptothecin	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 18774864]
Jurkat	GI₅₀	0.09 3 Compound: 1	Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay	[PMID: 21388138]
Jurkat	IC₅₀	0.1 3 Compound: 1; CPT	Anticancer activity against human Jurkat cells incubated for 48 hrs by MTT assay Anticancer activity against human Jurkat cells incubated for 48 hrs by MTT assay	[PMID: 34175539]
HEp-2	IC₅₀	0.7 3 Compound: Camptothecin	Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
Jurkat	IC₅₀	0.11 3 Compound: CPT, Camptothecin	Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay	[PMID: 24980118]
HEp-2	IC₅₀	3.01 3 Compound: CPT	Cytotoxicity against against human Hep2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human Hep2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
HEp-2	IC₅₀	3.04 3 Compound: CPT	Cytotoxicity against human Hep2 cells measured after 72 hrs by MTT assay Cytotoxicity against human Hep2 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
Jurkat	IC₅₀	1.4 1 Compound: camptothecin	Growth inhibition of human Jurkat cells after 96 hrs Growth inhibition of human Jurkat cells after 96 hrs	[PMID: 18061452]
Jurkat	IC₅₀	22 3 Compound: CPT	Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay	[PMID: 30853330]
HEp-2	IC₅₀	3.04 3 Compound: CPT	Cytotoxicity against human Hep2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human Hep2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
Jurkat	IC₅₀	51.5 3 Compound: CPT	Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay	[PMID: 30853330]
HFL1	IC₅₀	1.06 3 Compound: Camptothecin	Antiproliferative activity against HFL1 cells after 72 hrs by CCK8 assay Antiproliferative activity against HFL1 cells after 72 hrs by CCK8 assay	[PMID: 27643560]
K562	IC₅₀	< 0.003 3 Compound: CPT	Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
HGC-27	IC₅₀	0.166 3 Compound: CPT	Antiproliferative activity against human HGC-27 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
K562	IC₅₀	< 0.003 3 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 26226379]
HGC-27	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HGC-27 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
K562	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 24360564]
K562	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human K562 cells by MTT assay Cytotoxicity against human K562 cells by MTT assay	[PMID: 36924947]
K562	IC₅₀	0.04 3 Compound: camptothecin	Cytotoxicity against human K562 cells after 5 days by XTT assay Cytotoxicity against human K562 cells after 5 days by XTT assay	[PMID: 18076140]
K562	IC₅₀	0.04 3 Compound: camptothecin	Growth inhibition of K562 cells by XTT assay after 5 days Growth inhibition of K562 cells by XTT assay after 5 days	[PMID: 17411092]
K562	GI₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 21115210]
K562	GI₅₀	0.06 3 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by XTT assay Cytotoxicity against human K562 cells after 72 hrs by XTT assay	[PMID: 20591678]
K562	IC₅₀	0.07 3 Compound: CPT	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 30055465]
K562	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 4 days by ELISA reader assay Cytotoxicity against human K562 cells after 4 days by ELISA reader assay	[PMID: 19939682]
K562	IC₅₀	0.09 3 Compound: Camp	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
K562	IC₅₀	0.13 3 Compound: Camptothecin	Antitumor activity against human K562 cells incubated for 48 hrs by MTT assay Antitumor activity against human K562 cells incubated for 48 hrs by MTT assay	[PMID: 25590864]
K562	IC₅₀	0.32 3 Compound: CPT	Cytotoxicity against human K562 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
K562	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human K562 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
K562	IC₅₀	0.58 3 Compound: Camptothecin	Antitumor activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
K562	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human K562 cells by MTT assay Cytotoxicity against human K562 cells by MTT assay	[PMID: 21115246]
K562	IC₅₀	0.711 3 Compound: Camp	Induction of apoptosis in human K562 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human K562 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
K562	IC₅₀	1.18 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 2 days Cytotoxicity against human K562 cells after 2 days	[PMID: 22318164]
K562	IC₅₀	1.4 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human K562 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human K562 cells after 48 hrs by SRB assay	[PMID: 19715319]
K562	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against imatinib-resistant human K562 cells after 72 hrs by MTT assay Cytotoxicity against imatinib-resistant human K562 cells after 72 hrs by MTT assay	[PMID: 20590148]
HL-60	GI₅₀	0.03 3 Compound: camptothecin	Growth inhibition of human HL60 cells by Almar blue assay Growth inhibition of human HL60 cells by Almar blue assay	[PMID: 17418582]
K562	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against human imitinib-resistant K562 cells by MTT assay Cytotoxicity against human imitinib-resistant K562 cells by MTT assay	[PMID: 20329739]
HL-60	GI₅₀	1.7 1 Compound: CPT, camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 17962028]
K562	IC₅₀	2.69 3 Compound: Camptothecin	Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
K562	IC₅₀	31 1 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 24900725]
HL-60	GI₅₀	< 0.003 3 Compound: 1, CPT	Cytotoxicity against human HL60 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HL60 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
K562	IC₅₀	5.37 3 Compound: CPT	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 25599951]
HL-60	IC₅₀	0.0067 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells Antiproliferative activity against human HL60 cells	[PMID: 29429833]
KB	IC₅₀	< 0.005 6 Compound: 1 Camptothecin	In vitro cytotoxicity against KB cell line (human epidermoid carcinoma of the nasopharynx) using MTT assay In vitro cytotoxicity against KB cell line (human epidermoid carcinoma of the nasopharynx) using MTT assay	[PMID: 15225719]
HL-60	IC₅₀	0.013 3 Compound: camptothecin	Cytotoxicity against human HL60 cells Cytotoxicity against human HL60 cells	[PMID: 18178085]
HL-60	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 26188908]
KB	IC₅₀	< 0.013 3 Compound: CPT	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 20392545]
KB	IC₅₀	0.003 3 Compound: 1, CPT	Cytotoxicity against human KB cells after 4 days by MTT assay Cytotoxicity against human KB cells after 4 days by MTT assay	[PMID: 18554906]
HL-60	IC₅₀	0.017 3 Compound: 1, CPT	Cytotoxicity against human HL60 cells after 72 hrs by trypan blue assay Cytotoxicity against human HL60 cells after 72 hrs by trypan blue assay	[PMID: 21071230]
KB	CC₅₀	0.006 3 Compound: Camptothecin	Compound concentration required to reduce the exponential growth of KB cells by 50% Compound concentration required to reduce the exponential growth of KB cells by 50%	[PMID: 9767632]
HL-60	IC₅₀	0.018 3 Compound: 1, CPT	Cytotoxicity against human HL60 cells Cytotoxicity against human HL60 cells	[PMID: 21095131]
KB	IC₅₀	0.008 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of KB cell population by 50%. Inhibitory concentration that reduced the viability of KB cell population by 50%.	[PMID: 9003520]
HL-60	IC₅₀	0.018 3 Compound: CPT	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 21353568]
KB	EC₅₀	0.01 6 Compound: camptothecin	Cytotoxicity against human KB cells after 72 hrs by MTS method Cytotoxicity against human KB cells after 72 hrs by MTS method	[PMID: 11858737]
HL-60	IC₅₀	0.018 3 Compound: Camptothecin	Antiproliferation activity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Antiproliferation activity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32201190]
KB	IC₅₀	0.02 3 Compound: Camptothecin	Antiproliferative activity against human KB cells by SRB assay Antiproliferative activity against human KB cells by SRB assay	[PMID: 24200393]
HL-60	IC₅₀	0.018 3 Compound: camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 17498951]
KB	IC₅₀	0.037 3 Compound: 1, CPT	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 25003995]
HL-60	IC₅₀	0.019 3 Compound: Camptothecin	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by WST-1 assay Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by WST-1 assay	[PMID: 27318980]
KB	IC₅₀	0.037 3 Compound: 1	Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B colorimetric assay Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B colorimetric assay	[PMID: 26994847]
HL-60	IC₅₀	0.019 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells measured after 48 hrs by WST1 assay Antiproliferative activity against human HL60 cells measured after 48 hrs by WST1 assay	[PMID: 28477443]
HL-60	IC₅₀	0.02 3 Compound: Camp	Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
KB	IC₅₀	0.121 3 Compound: 1, CPT	Cytotoxicity against human KB cells by SRB assay Cytotoxicity against human KB cells by SRB assay	[PMID: 23102893]
HL-60	IC₅₀	0.035 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay	[PMID: 27096049]
KB	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human KB cells by SRB staining-based fluorescence cytometry Cytotoxicity against human KB cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
KB	ED₅₀	20.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human KB cells by sulforhodamine B assay Cytotoxicity against human KB cells by sulforhodamine B assay	[PMID: 17350834]
HL-60	IC₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 24041234]
HL-60	IC₅₀	0.065 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days Cytotoxicity against human HL60 cells after 2 days	[PMID: 21419530]
KB	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human KB cells by MTT assay Cytotoxicity against human KB cells by MTT assay	[PMID: 11858760]
KB	IC₅₀	38 1 Compound: camptothecin	Cytotoxicity against human KB cells after 72 hrs by MTS assay Cytotoxicity against human KB cells after 72 hrs by MTS assay	[PMID: 19655762]
HL-60	IC₅₀	0.065 3 Compound: camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 20093033]
HL-60	IC₅₀	0.066 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against HL-60 (human assay In vitro antiproliferative activity of compound against HL-60 (human assay	[PMID: 12639541]
KB	IC₅₀	50 1 Compound: 1	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 28927790]
KB	IC₅₀	50 1 Compound: 1; CPT	Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
HL-60	IC₅₀	0.067 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 19836231]
HL-60	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 25599951]
KB	IC₅₀	8.8 1 Compound: CPT	Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay	[PMID: 22698783]
KB 3-1	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human KB3-1 cells after 4 days by MTT assay Cytotoxicity against human KB3-1 cells after 4 days by MTT assay	[PMID: 18676151]
HL-60	IC₅₀	0.07 3 Compound: Camp	Induction of apoptosis in human HL60 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human HL60 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
KB 3-1	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human KB3-1 cells by MTT method Cytotoxicity against human KB3-1 cells by MTT method	[PMID: 18771930]
HL-60	IC₅₀	0.089 3 Compound: CPT	Cytotoxicity against human HL60 cells by sulforhodamine B assay Cytotoxicity against human HL60 cells by sulforhodamine B assay	[PMID: 19345580]
HL-60	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
KB-V1	IC₅₀	0.025 3 Compound: CPT	Cytotoxicity against human multidrug resistant MDR1 overexpressing human KBV1 cells after 4 days by MTT assay Cytotoxicity against human multidrug resistant MDR1 overexpressing human KBV1 cells after 4 days by MTT assay	[PMID: 18676151]
HL-60	IC₅₀	0.1 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days Cytotoxicity against human HL60 cells after 2 days	[PMID: 21601964]
KB-V1	IC₅₀	0.025 3 Compound: CPT	Cytotoxicity against human KBV1 cells by MTT method Cytotoxicity against human KBV1 cells by MTT method	[PMID: 18771930]
KG-1	IC₅₀	1.6 3 Compound: Camptothecin	Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 33161122]
HL-60	IC₅₀	0.42 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 30109008]
KG-1	IC₅₀	2.31 3 Compound: Camptothecin	Antitumor activity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
HL-60	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 20356735]
HL-60	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells after 2 days by MTT assay Cytotoxicity against human HL60 cells after 2 days by MTT assay	[PMID: 22325897]
L02	IC₅₀	> 150 3 Compound: CPT	Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
HL-60	IC₅₀	0.68 3 Compound: 1	Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells	[PMID: 8410981]
L02	IC₅₀	0.14 3 Compound: CPT	Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay	[PMID: 35612499]
L02	IC₅₀	2.15 3 Compound: CPT	Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
HL-60	IC₅₀	0.8 3 Compound: camptothecin	Cytotoxicity against human HL60 cells by rapid colorimetric assay Cytotoxicity against human HL60 cells by rapid colorimetric assay	[PMID: 19585998]
L1210	IC₅₀	0.014 3 Compound: 1	Concentration that inhibits the proliferation of L1210 cells by 50% Concentration that inhibits the proliferation of L1210 cells by 50%	[PMID: 2537428]
HL-60	IC₅₀	0.91 3 Compound: Camptothecin	Antitumor activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
L1210	IC₅₀	510 1 Compound: CPT	Cytotoxicity against mouse L1210 cells overexpressing folate receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against mouse L1210 cells overexpressing folate receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
HL-60	IC₅₀	0.92 3 Compound: Camptothecin	Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method	[PMID: 29131616]
LN-229	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human LN229 cells after 48 hrs by CCK8 assay Cytotoxicity against human LN229 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
HL-60	IC₅₀	1.7 3 Compound: Camptothecin	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 33161122]
HL-60	IC₅₀	130 3 Compound: Camptothecin	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 15974606]
LNCaP	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against hormone-dependent human LNCAP cells after 2 days by sulforhodamine B assay Cytotoxicity against hormone-dependent human LNCAP cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
HL-60	IC₅₀	5 1 Compound: CPT	Tested in vitro for growth inhibitory activity against HL60 (human promyelocytic leukemic) cells Tested in vitro for growth inhibitory activity against HL60 (human promyelocytic leukemic) cells	10.1016/S0960-894X(97)10181-0
LNCaP	ED₅₀	2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human LNCAP cells by sulforhodamine B assay Cytotoxicity against human LNCAP cells by sulforhodamine B assay	[PMID: 17350834]
HL-60	IC₅₀	6 1 Compound: camptothecin	Cytotoxicity against human HL60 cells after 72 hrs by MTS assay Cytotoxicity against human HL60 cells after 72 hrs by MTS assay	[PMID: 19655762]
LNCaP	IC₅₀	86.1 1 Compound: Camptothecin	Cytotoxicity against human LNCAP cells by MTT assay Cytotoxicity against human LNCAP cells by MTT assay	[PMID: 11858760]
LoVo	GI₅₀	0.008 3 Compound: 1	Cytotoxicity against human LoVo cells after 72 hrs by MTT assay Cytotoxicity against human LoVo cells after 72 hrs by MTT assay	[PMID: 21388138]
HL-60	IC₅₀	< 0.064 3 Compound: CPT; 1	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 30509782]
LoVo	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human LoVo cells after 48 hrs by CCK8 assay Cytotoxicity against human LoVo cells after 48 hrs by CCK8 assay	[PMID: 30702286]
HL60/MX2	GI₅₀	1.5 1 Compound: CPT, camptothecin	Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay	[PMID: 17962028]
LoVo	IC₅₀	1.54 3 Compound: 1; CPT	Antiproliferative activity against human LoVo cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cell line Antiproliferative activity against human HOP62 cell line	[PMID: 16442283]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells Cytotoxicity against human HOP62 cells	[PMID: 17402722]
LoVo	IC₅₀	3.1 3 Compound: CPT	Cytotoxicity against human LoVo cells after 3 days by MTT assay Cytotoxicity against human LoVo cells after 3 days by MTT assay	[PMID: 20942490]
LOX IMVI	IC₅₀	48 1 Compound: 1	Cytotoxicity was determined in vitro in LOX cells (melanoma) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in LOX cells (melanoma) of human tumor cell lines by using MTT assay	[PMID: 7853331]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells Antiproliferative activity against human HOP62 cells	[PMID: 18630891]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells Cytotoxicity against human HOP62 cells	[PMID: 19783447]
Lu1	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against human Lu1 cells after 2 days by sulforhodamine B assay Cytotoxicity against human Lu1 cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
Lu1	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human Lu1 cells by MTT assay Cytotoxicity against human Lu1 cells by MTT assay	[PMID: 11858760]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells Cytotoxicity against human HOP62 cells	[PMID: 20630766]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells by SRB assay Antiproliferative activity against human HOP62 cells by SRB assay	[PMID: 21710981]
LX-1	IC₅₀	0.12 3 Compound: camptothecin	Cytotoxicity against human LX1 cells after 72 hrs by MTS method Cytotoxicity against human LX1 cells after 72 hrs by MTS method	[PMID: 11858737]
M059J	IC₅₀	5.5 3 Compound: CPT	Cytotoxicity against human M059J cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human M059J cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay	[PMID: 21823606]
Mahlavu	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 22409771]
HOP-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human HOP62 cells by SRB assay Cytotoxicity against human HOP62 cells by SRB assay	[PMID: 24502276]
Mahlavu	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HOP-62	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human HOP62 cells after 48 hrs by SRB assay Growth inhibition of human HOP62 cells after 48 hrs by SRB assay	[PMID: 24800942]
MCF10	IC₅₀	24.77 3 Compound: Camptothecin	Cytotoxicity against human MCF10 cells assessed as reduction in cell viability after 3 hrs by MTT assay Cytotoxicity against human MCF10 cells assessed as reduction in cell viability after 3 hrs by MTT assay	[PMID: 33962153]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells after 48 hrs Antiproliferative activity against human HOP62 cells after 48 hrs	[PMID: 27070999]
MCF-10A	IC₅₀	0.27 3 Compound: CPT	Cytotoxicity against human MCF10A cells after 2 days Cytotoxicity against human MCF10A cells after 2 days	[PMID: 24904965]
HOP-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human HOP62 cells assessed as growth inhibition Antiproliferative activity against human HOP62 cells assessed as growth inhibition	[PMID: 28657311]
HOP-62	GI₅₀	0.01 3 Compound: 1, CPT	Antiproliferative activity against human HOP62 cells Antiproliferative activity against human HOP62 cells	[PMID: 20155916]
MCF-10A	IC₅₀	0.97 3 Compound: Camptothecin	Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay	[PMID: 26361737]
HOP-62	GI₅₀	0.01 3 Compound: 1, Camptothecin	Cytotoxicity against human HOP62 cells Cytotoxicity against human HOP62 cells	[PMID: 17676830]
MCF-10A	IC₅₀	2.19 3 Compound: 1; CPT	Antiproliferative activity against human MCF-10A cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF-10A cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
MCF-10A	IC₅₀	2.58 3 Compound: CPT	Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
HOP-62	GI₅₀	0.01 3 Compound: 2	Growth inhibitory activity against human lung HOP-62 cell line Growth inhibitory activity against human lung HOP-62 cell line	[PMID: 15509164]
HOP-62	GI₅₀	0.01 3 Compound: 2	Antiproliferative activity against human HOP62 cell line Antiproliferative activity against human HOP62 cell line	[PMID: 16913702]
MCF-12A	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MCF12A cells after 3 days by SRB assay Cytotoxicity against human MCF12A cells after 3 days by SRB assay	[PMID: 23142674]
HOP-62	GI₅₀	0.01 3 Compound: 2	Cytotoxicity against human HOP62 cells Cytotoxicity against human HOP62 cells	[PMID: 17696418]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
HOP-62	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
HOP-62	GI₅₀	0.01 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human lung HOP-62 cell line Antiproliferative activity was determined for 50% growth inhibition against human lung HOP-62 cell line	[PMID: 11020283]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
HOP-62	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay Cytotoxicity against human HOP62 cells after 48 hrs by SRB assay	[PMID: 28418653]
MCF7	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human MCF7 cells after 72 hrs by MTT assay Growth inhibition of human MCF7 cells after 72 hrs by MTT assay	[PMID: 24180210]
HOS	IC₅₀	0.049 3 Compound: CPT	Cytotoxicity against human HOS cells incubated for 48 hrs by MTT assay Cytotoxicity against human HOS cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
MCF7	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 23142674]
MCF7	IC₅₀	< 0.024 6 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay	[PMID: 24940955]
HT-1080	IC₅₀	0.08 3 Compound: 1, CPT	Cytotoxicity against human HT1080 cells Cytotoxicity against human HT1080 cells	[PMID: 21095131]
HT-1080	IC₅₀	0.08 3 Compound: CPT	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 21353568]
MCF7	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 22409771]
MCF7	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HT-1080	IC₅₀	0.08 3 Compound: camptothecin	Cytotoxicity against human HT1080 cells by SRB assay Cytotoxicity against human HT1080 cells by SRB assay	[PMID: 17498951]
MCF7	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
MCF7	IC₅₀	≤ 0.1 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
MCF7	IC₅₀	0.0005 3 Compound: 3	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 25084144]
MCF7	IC₅₀	0.0006 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 25247770]
MCF7	GI₅₀	0.002 3 Compound: Camptothecin	Growth inhibition of human MCF7 cells after 48 hrs by MTT assay Growth inhibition of human MCF7 cells after 48 hrs by MTT assay	[PMID: 23357037]
MCF7	IC₅₀	0.003 3 Compound: 3	Cytotoxicity against human MCF7 cells in presence of 10 mM DTT after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells in presence of 10 mM DTT after 48 hrs by SRB assay	[PMID: 25084144]
MCF7	GI₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23831811]
MCF7	GI₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21115210]
MCF7	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 24800942]
MCF7	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 21710981]
MCF7	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of adriamycin-resistant MCF7 cells after 4 days Growth inhibition of adriamycin-resistant MCF7 cells after 4 days	[PMID: 17418582]
MCF7	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of MCF7 cells after 4 days Growth inhibition of MCF7 cells after 4 days	[PMID: 17418582]
MCF7	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human MCF7 cells after 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs	[PMID: 27070999]
MCF7	GI₅₀	0.012 3 Compound: CPT	Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
MCF7	GI₅₀	0.013 3 Compound: 18	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 28418653]
MCF7	GI₅₀	0.013 3 Compound: 1	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 21823606]
MCF7	GI₅₀	0.013 3 Compound: 1	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 24502276]
MCF7	GI₅₀	0.013 3 Compound: 2	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
MCF7	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 20392545]
MCF7	CC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22047799]
MCF7	IC₅₀	0.021 3 Compound: CPT	In-vitro antitumor activity against human MCF7 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human MCF7 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
MCF7	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
HT-29	EC₅₀	60 1 Compound: Camptothecin	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 20825206]
HT-29	ED₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay	[PMID: 20939540]
MCF7	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 28274626]
MCF7	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
HT-29	ED₅₀	0.06 3 Compound: camptothecin	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 19839614]
MCF7	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 17254669]
MCF7	IC₅₀	0.056 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 21978950]
HT-29	GI₅₀	0.03 3 Compound: 1, CPT	Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	IC₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay	[PMID: 19939682]
HT-29	GI₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 21115210]
MCF7	GI₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HT-29	GI₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 23831811]
MCF7	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 21513293]
HT-29	IC₅₀	0.014 3 Compound: camptothecin	Growth inhibition of human HT29 cells by neutral red assay Growth inhibition of human HT29 cells by neutral red assay	[PMID: 17204425]
MCF7	EC₅₀	0.072 3 Compound: camptothecin	Cytotoxicity against human MCF7 after 3 days by SRB assay Cytotoxicity against human MCF7 after 3 days by SRB assay	[PMID: 15730238]
HT-29	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
HT-29	IC₅₀	0.06 3 Compound: CPT	Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 24360564]
MCF7	IC₅₀	0.073 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay	[PMID: 28409637]
MCF7	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay	[PMID: 25481396]
HT-29	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 36924947]
MCF7	CC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22884523]
HT-29	IC₅₀	0.0878 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of HT 29 cell population by 50%. Inhibitory concentration that reduced the viability of HT 29 cell population by 50%.	[PMID: 9003520]
MCF7	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells incubated for 3 days by SRB assay Cytotoxicity against human MCF7 cells incubated for 3 days by SRB assay	[PMID: 22863526]
HT-29	IC₅₀	0.09 3 Compound: 1, CPT	Cytotoxicity against human HT29 cells after 4 days by MTT assay Cytotoxicity against human HT29 cells after 4 days by MTT assay	[PMID: 18554906]
HT-29	IC₅₀	0.12 3 Compound: 1, CPT	Antitumor activity against human HT-29 cells by SRB method Antitumor activity against human HT-29 cells by SRB method	[PMID: 19541483]
MCF7	IC₅₀	0.084 3 Compound: CPT	Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
HT-29	IC₅₀	0.19 3 Compound: CPT	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
MCF7	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human MCF7 cells after 4 days by MTT assay Cytotoxicity against human MCF7 cells after 4 days by MTT assay	[PMID: 18554906]
MCF7	GI₅₀	0.28 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
HT-29	IC₅₀	0.4 3 Compound: 1, CPT	Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	IC₅₀	0.34 3 Compound: Camp	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
HT-29	IC₅₀	0.7 1 Compound: Camptothecin	Antiproliferative activity against human HT-29 cells by SRB assay Antiproliferative activity against human HT-29 cells by SRB assay	[PMID: 24200393]
MCF7	IC₅₀	0.35 3 Compound: CPT	Cytotoxicity against human MCF7 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
HT-29	IC₅₀	0.85 3 Compound: camptothecin	Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 20093033]
MCF7	GI₅₀	0.35 3 Compound: CPT	Cytotoxicity against human MCF-7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF-7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
HT-29	IC₅₀	1.07 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 19836231]
HT-29	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human HT-29 cells by SRB staining-based fluorescence cytometry Cytotoxicity against human HT-29 cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
MCF7	IC₅₀	0.42 3 Compound: CPT	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30125725]
HT-29	IC₅₀	1.37 3 Compound: CPT	Antiproliferative activity against human HT-29 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
MCF7	IC₅₀	0.56 3 Compound: 1; CPT	Antiproliferative activity against human MCF7 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
MCF7	GI₅₀	0.57 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay	[PMID: 20591678]
HT-29	IC₅₀	1.4 3 Compound: Camptothecin	In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line aws determined by SRB assay In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line aws determined by SRB assay	[PMID: 12639541]
MCF7	IC₅₀	0.65 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21186067]
HT-29	IC₅₀	1.87 3 Compound: CPT	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
MCF7	IC₅₀	0.68 3 Compound: CPT; 1	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30509782]
HT-29	IC₅₀	10 3 Compound: Camptothecin	Cytotoxicity against human HT-29 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 21843907]
HT-29	IC₅₀	2 3 Compound: camptothecin	Cytotoxicity against human HT29 cells by MTT assay Cytotoxicity against human HT29 cells by MTT assay	[PMID: 18841903]
MCF7	IC₅₀	0.68 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30600208]
HT-29	IC₅₀	2.35 3 Compound: CPT	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38128233]
MCF7	IC₅₀	1.1 3 Compound: 1, CPT	Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by SRB staining-based fluorescence cytometry Cytotoxicity against human MCF7 cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
HT-29	IC₅₀	260 1 Compound: 1a	Cytotoxicity against human HT-29 cells after 72 hrs by alamar blue assay Cytotoxicity against human HT-29 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HT-29	IC₅₀	3.16 3 Compound: 1, CPT	Cytotoxicity against human HT29 cells after 1 hr Cytotoxicity against human HT29 cells after 1 hr	[PMID: 18419110]
MCF7	IC₅₀	1.6 1 Compound: Camptothecin	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 22376176]
HT-29	IC₅₀	3.16 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against human HT29 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against human HT29 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
MCF7	IC₅₀	1.6 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 21410162]
MCF7	IC₅₀	1.67 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
HT-29	IC₅₀	30 1 Compound: camptothecin	Antiproliferative activity against human HT29 cell line Antiproliferative activity against human HT29 cell line	[PMID: 16686539]
HT-29	IC₅₀	46 1 Compound: 1	Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay	[PMID: 7853331]
MCF7	IC₅₀	1.8 3 Compound: camptothecin	Cytotoxicity against human tamoxifen-resistant MCF7 cells by WST-1 assay Cytotoxicity against human tamoxifen-resistant MCF7 cells by WST-1 assay	[PMID: 22197145]
MCF7	IC₅₀	10 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 19655762]
HT-29	IC₅₀	8.81 3 Compound: 1, CPT	Cytotoxicity against human mitoxantrone-resistant HT29 cells after 1 hr Cytotoxicity against human mitoxantrone-resistant HT29 cells after 1 hr	[PMID: 18419110]
HT-29	IC₅₀	8.81 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against BCRP overexpressing mitoxantrone-resistant human HT29 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against BCRP overexpressing mitoxantrone-resistant human HT29 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
MCF7	IC₅₀	10 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 18841903]
MCF7	IC₅₀	13.62 3 Compound: Camptothecin	Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
HT-29	IC₅₀	80 1 Compound: CPT	Cytotoxicity against HT-29 tumor cell line determined by WST-1 assay Cytotoxicity against HT-29 tumor cell line determined by WST-1 assay	[PMID: 10841808]
HT-29	IC₅₀	> 100 3 Compound: CPT	Cytotoxicity against human HT-29 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
MCF7	IC₅₀	14.2 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 4 days by MTT assay Cytotoxicity against human MCF7 cells after 4 days by MTT assay	[PMID: 20619511]
HT-29	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
MCF7	IC₅₀	160 1 Compound: Camptothecin	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
MCF7	IC₅₀	2.43 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 21115246]
MCF7	IC₅₀	2.5 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hr by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hr by MTT assay	[PMID: 32682183]
MCF7	IC₅₀	2.5 3 Compound: CPT	Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis	[PMID: 30897325]
MCF7	IC₅₀	2.6 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by WST-1 assay Cytotoxicity against human MCF7 cells by WST-1 assay	[PMID: 22197145]
MCF7	IC₅₀	2.8 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
MCF7	IC₅₀	26 1 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24900725]
HUVEC	ED₅₀	258 1 Compound: camptothecin	Cytotoxicity against HUVEC Cytotoxicity against HUVEC	[PMID: 15043407]
MCF7	IC₅₀	28.66 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28462840]
HUVEC	IC₅₀	0.01 3 Compound: CPT	Cytotoxicity against human HUVEC cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HUVEC cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
MCF7	IC₅₀	3 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay	[PMID: 19655762]
HUVEC	IC₅₀	0.012 3 Compound: CPT	In-vitro cytotoxic activity against human HUVEC cells incubated for 72 hrs by CCK8 assay In-vitro cytotoxic activity against human HUVEC cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
MCF7	ED₅₀	3.2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human MCF7 cells by sulforhodamine B assay Cytotoxicity against human MCF7 cells by sulforhodamine B assay	[PMID: 17350834]
HUVEC	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
HUVEC	IC₅₀	0.06 3 Compound: CPT	Cytotoxicity against HUVEC cells Cytotoxicity against HUVEC cells	[PMID: 36924947]
MCF7	GI₅₀	3.21 3 Compound: CPT	Cytotoxicity against human MCF-7/TDP1 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF-7/TDP1 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
HUVEC	IC₅₀	0.2 3 Compound: Camptothecin	Toxicity against HUVEC incubated for 48 hrs by MTT assay Toxicity against HUVEC incubated for 48 hrs by MTT assay	[PMID: 25590864]
MCF7	IC₅₀	3.3 1 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 24200393]
MCF7	IC₅₀	3.91 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days Cytotoxicity against human MCF7 cells after 2 days	[PMID: 22318164]
MCF7	IC₅₀	4.54 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
MCF7	GI₅₀	6 3 Compound: 1	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21388138]
MCF7	IC₅₀	6 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
MCF7	IC₅₀	65.1 1 Compound: CPT	Cytotoxicity against human MCF7 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
MCF7	IC₅₀	7.42 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 3 days Cytotoxicity against human MCF7 cells after 3 days	[PMID: 19954977]
HeLa	ED₅₀	0.19 6 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 18220355]
MCF7	IC₅₀	71.3 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
HeLa	GI₅₀	0.0054 3 Compound: CPT	Growth inhibition of human HeLa cells after 72 hrs by trypan blue assay Growth inhibition of human HeLa cells after 72 hrs by trypan blue assay	[PMID: 27597409]
MCF7	IC₅₀	87.5 1 Compound: 1	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 28927790]
MCF7	IC₅₀	87.5 1 Compound: 1; CPT	Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
HeLa	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of HeLa cells after 4 days Growth inhibition of HeLa cells after 4 days	[PMID: 17418582]
HeLa	GI₅₀	0.04 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay	[PMID: 19715319]
MDA-MB-157	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human MDA-MB-157 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-157 cells after 3 days by SRB assay	[PMID: 23142674]
HeLa	GI₅₀	0.05 3 Compound: Camptothecin	Growth inhibition of human HeLa cells after 48 hrs by MTT assay Growth inhibition of human HeLa cells after 48 hrs by MTT assay	[PMID: 23357037]
MDA-MB-231	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 23142674]
HeLa	GI₅₀	0.08 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20662543]
MDA-MB-231	IC₅₀	> 6.4 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Top1 assessed as cell viability by MTT assay Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Top1 assessed as cell viability by MTT assay	[PMID: 34844412]
HeLa	GI₅₀	0.18 3 Compound: 1, camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 18180162]
MDA-MB-231	IC₅₀	0.17 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 34171512]
MDA-MB-231	IC₅₀	0.241 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
HeLa	GI₅₀	0.19 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HeLa	GI₅₀	0.6 3 Compound: Camptothecin	Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay	[PMID: 15026047]
MDA-MB-231	IC₅₀	0.291 3 Compound: camptothecin	Growth inhibition of human MDA-MB-231 cells by neutral red assay Growth inhibition of human MDA-MB-231 cells by neutral red assay	[PMID: 17204425]
MDA-MB-231	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
HeLa	GI₅₀	0.6 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay	[PMID: 23831507]
MDA-MB-231	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human MDA231 cells after 48 hrs by CCK8 assay Cytotoxicity against human MDA231 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
HeLa	GI₅₀	0.6 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay Antiproliferative activity against human HeLa cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay	[PMID: 37531922]
HeLa	GI₅₀	1.3 3 Compound: 1	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21388138]
MDA-MB-231	IC₅₀	0.33 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 after 48 hrs by SRB assay Cytotoxicity against human MDA-MB-231 after 48 hrs by SRB assay	[PMID: 21044847]
HeLa	GI₅₀	1.3 3 Compound: CPT	Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
MDA-MB-231	IC₅₀	0.342 3 Compound: CPT, Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay	[PMID: 24980118]
MDA-MB-231	GI₅₀	0.4 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
HeLa	IC₅₀	0.0089 3 Compound: 1, CPT	Cytotoxicity against human HeLa cells after 72 hrs by trypan blue assay Cytotoxicity against human HeLa cells after 72 hrs by trypan blue assay	[PMID: 21071230]
HeLa	IC₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28384547]
MDA-MB-231	IC₅₀	0.42 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HeLa	IC₅₀	0.072 3 Compound: CPT	Cytotoxicity against human HeLa cells by sulforhodamine B assay Cytotoxicity against human HeLa cells by sulforhodamine B assay	[PMID: 19345580]
MDA-MB-231	IC₅₀	0.49 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
MDA-MB-231	IC₅₀	0.68 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells by MTT assay Cytotoxicity against human MDA-MB-231 cells by MTT assay	[PMID: 19836231]
HeLa	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay	[PMID: 28557449]
MDA-MB-231	IC₅₀	0.92 3 Compound: camptothecin	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 20093033]
HeLa	IC₅₀	0.09 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28068603]
HeLa	IC₅₀	0.108 3 Compound: CPT	Cytotoxicity against human HeLa cells measured after 72 hrs Cytotoxicity against human HeLa cells measured after 72 hrs	[PMID: 38716896]
MDA-MB-231	IC₅₀	0.97 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 2 days Cytotoxicity against human MDA-MB-231 cells after 2 days	[PMID: 21419530]
MDA-MB-231	IC₅₀	1.06 3 Compound: CPT	Cytotoxicity against HER-negative human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-negative human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
HeLa	IC₅₀	0.12 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay	[PMID: 28425292]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells by SRB assay Antiproliferative activity against human HeLa cells by SRB assay	[PMID: 24200393]
MDA-MB-231	IC₅₀	1.1 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 3 days Cytotoxicity against human MDA-MB-231 cells after 3 days	[PMID: 19954977]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
MDA-MB-231	GI₅₀	1.3 3 Compound: Camptothecin	Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay	[PMID: 20438092]
MDA-MB-231	IC₅₀	16.44 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 30109008]
HeLa	IC₅₀	0.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
MDA-MB-231	IC₅₀	162 1 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 24900725]
HeLa	IC₅₀	0.18 3 Compound: CPT	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
MDA-MB-231	IC₅₀	2.11 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
HeLa	IC₅₀	0.18 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay	[PMID: 26945111]
MDA-MB-231	IC₅₀	2.7 3 Compound: camptothecin	Cytotoxicity against human MDA-MB-231 cells by WST-1 assay Cytotoxicity against human MDA-MB-231 cells by WST-1 assay	[PMID: 22197145]
HeLa	IC₅₀	0.18 3 Compound: camptothecin	Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay	[PMID: 25936262]
HeLa	IC₅₀	0.19 6 Compound: camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 18774864]
MDA-MB-231	IC₅₀	23.98 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
MDA-MB-231	IC₅₀	264 1 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Ctrl assessed as cell viability by MTT assay Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Ctrl assessed as cell viability by MTT assay	[PMID: 34844412]
HeLa	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human HeLa cells after 48 hrs by SRB assay	[PMID: 19715319]
MDA-MB-231	IC₅₀	28.4 1 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay	[PMID: 32952994]
HeLa	IC₅₀	0.23 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human HeLa cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
HeLa	IC₅₀	0.28 6 Compound: Camptothecin	Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay	10.1007/s00044-010-9381-7
MDA-MB-231	IC₅₀	307 1 Compound: 1	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay	[PMID: 28927790]
HeLa	IC₅₀	0.4 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTS assay Cytotoxicity against human HeLa cells after 48 hrs by MTS assay	[PMID: 22542106]
MDA-MB-231	IC₅₀	307 1 Compound: 1; CPT	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
HeLa	IC₅₀	0.4 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTS assay Cytotoxicity against human HeLa cells after 48 hrs by MTS assay	[PMID: 23153813]
MDA-MB-231	IC₅₀	4.2 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay	[PMID: 20619511]
MDA-MB-231	IC₅₀	5.77 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay	[PMID: 26602827]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
MDA-MB-231	IC₅₀	540 1 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 21601964]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay	[PMID: 25481396]
MDA-MB-231	IC₅₀	8.83 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
MDA-MB-361	IC₅₀	0.17 3 Compound: CPT	Cytotoxicity against human MDA-MB-361 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-361 cells after 3 days by SRB assay	[PMID: 23142674]
HeLa	IC₅₀	0.4 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 27643560]
MDA-MB-435	IC₅₀	< 0.001 3 Compound: 1, CPT	Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay	[PMID: 24069881]
HeLa	IC₅₀	0.41 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
MDA-MB-435	GI₅₀	0.033 3 Compound: 1, CPT	Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HeLa	IC₅₀	0.42 3 Compound: CPT, Camptothecin	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24980118]
HeLa	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 24 to 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
MDA-MB-435	IC₅₀	0.0436 3 Compound: CPT	Antiproliferative activity against human MDA-MB-435 cells after 3 days by MTT assay Antiproliferative activity against human MDA-MB-435 cells after 3 days by MTT assay	[PMID: 23084702]
MDA-MB-435	IC₅₀	0.31 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HeLa	IC₅₀	0.5 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human HeLa cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
HeLa	IC₅₀	0.5 3 Compound: camptothecine	Cytotoxicity against human HeLa cells by MTT method Cytotoxicity against human HeLa cells by MTT method	[PMID: 17547457]
MDA-MB-435	IC₅₀	0.71 3 Compound: CPT	Cytotoxicity against human MDA-MB-435 cells after 3 days by MTT assay Cytotoxicity against human MDA-MB-435 cells after 3 days by MTT assay	[PMID: 20942490]
MDA-MB-435	IC₅₀	1 3 Compound: CPT	Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay	[PMID: 26226379]
HeLa	IC₅₀	0.58 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 19836231]
MDA-MB-435	IC₅₀	2.7 3 Compound: CPT	Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
HeLa	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 3 days by CCK8 assay Cytotoxicity against human HeLa cells after 3 days by CCK8 assay	[PMID: 26927425]
HeLa	IC₅₀	0.63 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay	[PMID: 19939682]
MDA-MB-436	IC₅₀	31.86 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-436 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human MDA-MB-436 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
HeLa	IC₅₀	0.63 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells in presence of 10% fetal bovine serum Cytotoxicity against human HeLa cells in presence of 10% fetal bovine serum	[PMID: 20188578]
MDA-MB-453	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MDA-MB-453 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-453 cells after 3 days by SRB assay	[PMID: 23142674]
HeLa	IC₅₀	0.66 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30125725]
MDA-MB-468	IC₅₀	1.71 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
MDA-MB-468	IC₅₀	14.76 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-468 cells after 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-468 cells after 72 hrs by SRB assay	[PMID: 26602827]
HeLa	IC₅₀	0.86 3 Compound: camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20093033]
HeLa	IC₅₀	0.94 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 20356735]
MEF	IC₅₀	5.87 6 Compound: Camptothecin	Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay	[PMID: 25867737]
MES-SA	IC₅₀	57 1 Compound: 1a	Cytotoxicity against human MESSA cells after 72 hrs by alamar blue assay Cytotoxicity against human MESSA cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HeLa	IC₅₀	0.94 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 24 hrs by crystal violet staining-based assay Antiproliferative activity against human HeLa cells after 24 hrs by crystal violet staining-based assay	[PMID: 29407986]
HeLa	IC₅₀	1.01 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 22318164]
MES-SA/Dx5	IC₅₀	52 1 Compound: 1a	Cytotoxicity against human MES-SA/Dx5 cells overexpressing MDR1 after 72 hrs by alamar blue assay Cytotoxicity against human MES-SA/Dx5 cells overexpressing MDR1 after 72 hrs by alamar blue assay	[PMID: 21341674]
MFE-296	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HeLa	IC₅₀	1.08 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 2 days Cytotoxicity against human HeLa cells after 2 days	[PMID: 21419530]
HeLa	IC₅₀	1.08 3 Compound: camptothecin	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 18178085]
MGC-803	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
MGC-803	IC₅₀	2.96 3 Compound: CPT	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 30685528]
HeLa	IC₅₀	1.1 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 4 days by MTT assay Cytotoxicity against human HeLa cells after 4 days by MTT assay	[PMID: 20619511]
MGC-803	IC₅₀	4.27 3 Compound: CPT	Antiproliferative activity against human MGC803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
HeLa	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human HeLa cells by SRB staining-based fluorescence cytometry Cytotoxicity against human HeLa cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
HeLa	IC₅₀	1.3 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 30007563]
MGC-803	IC₅₀	9.45 3 Compound: Camptothecin	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28462840]
MHCC97H	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human MHCC97H cells after 48 hrs by CCK8 assay Cytotoxicity against human MHCC97H cells after 48 hrs by CCK8 assay	[PMID: 30702286]
HeLa	IC₅₀	1.37 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
HeLa	IC₅₀	1.37 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
MIA PaCa-2	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
MIA PaCa-2	IC₅₀	0.18 3 Compound: CPT	Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in presence of type 1 collagen coated surface by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in presence of type 1 collagen coated surface by MTT assay	[PMID: 28689976]
HeLa	IC₅₀	1.41 3 Compound: 1; CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 27416553]
HeLa	IC₅₀	1.5 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21186067]
MIA PaCa-2	IC₅₀	0.19 3 Compound: Camptothecin	Antiproliferative activity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
HeLa	IC₅₀	1.57 3 Compound: CPT	Cytotoxicity against human HeLa cells after 24 hrs by MTS assay Cytotoxicity against human HeLa cells after 24 hrs by MTS assay	[PMID: 22542106]
MIA PaCa-2	IC₅₀	0.19 3 Compound: Camptothecin	Cytotoxicity against human MIAPaCa2 cells after 48 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells after 48 hrs by MTT assay	[PMID: 24041234]
MIA PaCa-2	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay	[PMID: 21775156]
HeLa	IC₅₀	1.57 3 Compound: CPT	Cytotoxicity against human HeLa cells after 24 hrs by MTS assay Cytotoxicity against human HeLa cells after 24 hrs by MTS assay	[PMID: 23153813]
MOLT-4	IC₅₀	0.04 1 Compound: CPT	Cytotoxicity against human MOLT4 cells after 72 hrs by MTT assay Cytotoxicity against human MOLT4 cells after 72 hrs by MTT assay	[PMID: 24900725]
HeLa	IC₅₀	1.59 3 Compound: CPT	Cytotoxicity against human HeLa cells measured after 2 days by MTT assay Cytotoxicity against human HeLa cells measured after 2 days by MTT assay	[PMID: 26334499]
MRC5	CC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay	[PMID: 22884523]
HeLa	IC₅₀	1.66 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 32932211]
MRC5	CC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay	[PMID: 22047799]
HeLa	IC₅₀	1.85 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 3 days Cytotoxicity against human HeLa cells after 3 days	[PMID: 19954977]
MRC5	IC₅₀	0.8 3 Compound: CPT	Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 3 days by resazurin staining based analysis Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 3 days by resazurin staining based analysis	[PMID: 34952177]
HeLa	IC₅₀	10.1 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28462840]
HeLa	IC₅₀	11.36 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as decrease in cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell proliferation after 48 hrs by MTT assay	[PMID: 27667553]
MRC5	IC₅₀	1.7 x 10^-5 3 Compound: CPT	Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
MRC5	IC₅₀	1.7 3 Compound: I; CPT	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
HeLa	IC₅₀	11.62 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25599951]
MSTO-211H	GI₅₀	0.0021 3 Compound: CPT	Growth inhibition of human MSTO-211H cells after 72 hrs by trypan blue assay Growth inhibition of human MSTO-211H cells after 72 hrs by trypan blue assay	[PMID: 27597409]
HeLa	IC₅₀	117.2 1 Compound: Camptothecin (table 1)	Concentration required to inhibit growth of human cervical HeLa carcinoma cell line Concentration required to inhibit growth of human cervical HeLa carcinoma cell line	[PMID: 15454230]
HeLa	IC₅₀	127 3 Compound: Camptothecin	Inhibitory activity against DNA topoisomerase-1 obtained from Hela cells Inhibitory activity against DNA topoisomerase-1 obtained from Hela cells	[PMID: 7699697]
MT4	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human MT4 cells after 96 hrs by MTT assay Cytotoxicity against human MT4 cells after 96 hrs by MTT assay	[PMID: 22884523]
MT4	IC₅₀	0.004 3 Compound: CPT	Antiproliferative activity against human MT4 cells by MTT assay Antiproliferative activity against human MT4 cells by MTT assay	[PMID: 17254669]
HeLa	IC₅₀	14 3 Compound: CPT	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 26188908]
HeLa	IC₅₀	19.8 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
MT4	IC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human MT4 cells after 96 hrs Cytotoxicity against human MT4 cells after 96 hrs	[PMID: 22276775]
MT4	CC₅₀	0.01 3 Compound: Camptothecin	Compound concentration required to reduce the exponential growth of MT-4 cells by 50% Compound concentration required to reduce the exponential growth of MT-4 cells by 50%	[PMID: 9767632]
HeLa	IC₅₀	2.62 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay	[PMID: 28633898]
HeLa	IC₅₀	24 1 Compound: CPT	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 24900725]
MX1	IC₅₀	1700 1 Compound: CPT	Cytotoxicity against human MX1 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MX1 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
HeLa	IC₅₀	3.8 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28511910]
NB-4	IC₅₀	2.01 3 Compound: Camptothecin	Antitumor activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
NCI/ADR-RES	IC₅₀	0.8 3 Compound: camptothecin	Cytotoxicity against human MCF7/ADR cells by WST-1 assay Cytotoxicity against human MCF7/ADR cells by WST-1 assay	[PMID: 22197145]
HeLa	IC₅₀	59.13 3 Compound: Camptothecin	Growth inhibition of human HeLa cells after 72 hrs by MTT assay Growth inhibition of human HeLa cells after 72 hrs by MTT assay	[PMID: 27344492]
NCI-H1299	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human NCI-H1299 cells by MTT assay Cytotoxicity against human NCI-H1299 cells by MTT assay	[PMID: 28506750]
HeLa	IC₅₀	6 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
HeLa	IC₅₀	6.13 3 Compound: Camptothecin	Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay	[PMID: 26602827]
NCI-H1299	IC₅₀	3.14 3 Compound: CPT	Antiproliferative activity against human H1299 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human H1299 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
NCI-H1975	IC₅₀	1.2 3 Compound: Camptothecin	Cytotoxicity against human NCI-H1975 cells by MTT assay Cytotoxicity against human NCI-H1975 cells by MTT assay	[PMID: 28506750]
HeLa	IC₅₀	6.51 3 Compound: CPT	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30685528]
HeLa	IC₅₀	60.01 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
NCI-H23	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human NCI-H23 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human NCI-H23 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
HeLa	IC₅₀	8.28 3 Compound: CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
NCI-H446	IC₅₀	> 200 3 Compound: CPT	Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
NCI-H446	IC₅₀	> 200 3 Compound: CPT	Cytotoxicity against human NCI-H446 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H446 cells after 72 hrs by MTT assay	[PMID: 26226379]
HeLa	IC₅₀	8.9 1 Compound: 1; CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 38421819]
HeLa	IC₅₀	8.93 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay	[PMID: 21983445]
NCI-H460	IC₅₀	< 0.04 3 Compound: Camptothecin	Cytotoxicity against human H460 cells after 72 hrs by MTS assay Cytotoxicity against human H460 cells after 72 hrs by MTS assay	[PMID: 21513293]
HeLa	IC₅₀	8.9 14 Compound: 1; CPT	Cytotoxicity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 38421819]
NCI-H460	IC₅₀	> 1000 1 Compound: 1a	Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay in presence of 40 mg/ml HSA Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay in presence of 40 mg/ml HSA	[PMID: 21341674]
NCI-H460	IC₅₀	> 25 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 20638158]
HeLa	IC₅₀	9 3 Compound: Camptothecin	Inhibition topoisomerase 1 in human HeLa cells assessed as conversion of supercoiled pBR322 DNA to relaxed form Inhibition topoisomerase 1 in human HeLa cells assessed as conversion of supercoiled pBR322 DNA to relaxed form	[PMID: 11430001]
HeLa	IC₅₀	> 300 3 Compound: CPT	Cytostatic activity against human HeLa cells after 24 hrs by CCK-8 assay Cytostatic activity against human HeLa cells after 24 hrs by CCK-8 assay	[PMID: 38278140]
NCI-H460	IC₅₀	0.002 3 Compound: Camptothecin	Cytotoxicity against human NCI-H460 cells incubated for 3 days by SRB assay Cytotoxicity against human NCI-H460 cells incubated for 3 days by SRB assay	[PMID: 22863526]
NCI-H460	GI₅₀	0.002 3 Compound: CPT	Growth inhibition of human H460 cells after 72 hrs by trypan blue assay Growth inhibition of human H460 cells after 72 hrs by trypan blue assay	[PMID: 27597409]
HeLa	IC₅₀	> 50 3 Compound: Camptothecin	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30109008]
Hep 3B2	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay	[PMID: 19715319]
NCI-H460	IC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by MTT assay	[PMID: 22758788]
NCI-H460	GI₅₀	0.0057 3 Compound: Camptothecin	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
Hep 3B2	IC₅₀	0.06 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human Hep3B cells after 48 hrs by SRB assay	[PMID: 19715319]
NCI-H460	IC₅₀	0.0062 3 Compound: 1, CPT	Cytotoxicity against human H460 cells after 72 hrs Cytotoxicity against human H460 cells after 72 hrs	[PMID: 18419110]
Hep 3B2	IC₅₀	102.9 3 Compound: CPT	Antiproliferative activity against human Hep3B cells at 2:1 compound:(2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diphenyl-ethyl]amino]-1-(1H-indo Antiproliferative activity against human Hep3B cells at 2:1 compound:(2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diphenyl-ethyl]amino]-1-(1H-indo	[PMID: 38278140]
NCI-H460	EC₅₀	0.0069 3 Compound: camptothecin	Cytotoxicity against human H460 after 3 days by SRB assay Cytotoxicity against human H460 after 3 days by SRB assay	[PMID: 15730238]
Hep 3B2	IC₅₀	434.29 1 Compound: CPT	Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth	[PMID: 37806498]
Hep 3B2	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
NCI-H460	GI₅₀	0.03 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay	[PMID: 20591678]
NCI-H460	IC₅₀	0.12 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
Hep 3B2	IC₅₀	> 300 3 Compound: CPT	Antiproliferative activity against human Hep3B cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against human Hep3B cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
NCI-H460	IC₅₀	0.18 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against human H460 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against human H460 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
Hep 3B2	IC₅₀	> 300 3 Compound: CPT	Antiproliferative activity against human Hep3B cells incubated for 24 hrs in presence of 12.5 uM (2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diph Antiproliferative activity against human Hep3B cells incubated for 24 hrs in presence of 12.5 uM (2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diph	[PMID: 38278140]
Hep 3B2	IC₅₀	> 300 3 Compound: CPT	Antiproliferative activity against human Hep3B cells incubated for 24 hrs in presence of 25 uM (2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diphen Antiproliferative activity against human Hep3B cells incubated for 24 hrs in presence of 25 uM (2R)-2,6-diamino-N-[(1R)-5-amino-1-[[(1R)-2-[[(1R)-2-[[(1R)-5-amino-1-[[(1R)-5-amino-1-[[(1R)-2-[[(1R)-1-[[(1R)-5-amino-1-carbamoyl-pentyl]carbamoyl]-2,2-diphen	[PMID: 38278140]
NCI-H460	IC₅₀	0.19 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
NCI-H460	IC₅₀	0.33 3 Compound: 1, CPT	Cytotoxicity against human H460 cells after 1 hr Cytotoxicity against human H460 cells after 1 hr	[PMID: 18419110]
NCI-H460	IC₅₀	0.33 3 Compound: 1, CPT	Antiproliferative activity against human NCI-H460 cells after short term exposure for 1 hr measured after 72 hrs in drug-free medium Antiproliferative activity against human NCI-H460 cells after short term exposure for 1 hr measured after 72 hrs in drug-free medium	[PMID: 19530720]
HepG2	CC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22047799]
NCI-H460	IC₅₀	110 1 Compound: Camptothecin	Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
HepG2	CC₅₀	0.04 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22884523]
HepG2	GI₅₀	0.1 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
NCI-H460	IC₅₀	13 1 Compound: 1a	Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HepG2	GI₅₀	0.22 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells incubated for 72 hrs by MTT assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
NCI-H460	IC₅₀	5 1 Compound: Cpt	Cytotoxicity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay	[PMID: 22749423]
HepG2	IC₅₀	0.01 3 Compound: CPT	Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
NCI-H460	IC₅₀	5.37 3 Compound: CPT	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
HepG2	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 36924947]
NCI-H69	IC₅₀	1 1 Compound: 1a	Cytotoxicity against human H69 cells after 72 hrs by alamar blue assay Cytotoxicity against human H69 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HepG2	IC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 96 hrs Cytotoxicity against human HepG2 cells after 96 hrs	[PMID: 22276775]
NCI-N87	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
HepG2	IC₅₀	0.03 3 Compound: CPT	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 17254669]
NCI-N87	IC₅₀	2.32 3 Compound: CPT	Cytotoxicity against HER-positive human NCI-N87 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human NCI-N87 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
HepG2	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
OVCAR-3	GI₅₀	0.22 3 Compound: 18	Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 28418653]
HepG2	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 24800942]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 21823606]
HepG2	IC₅₀	0.05 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24360564]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR3 cells by SRB assay Cytotoxicity against human OVCAR3 cells by SRB assay	[PMID: 24502276]
HepG2	IC₅₀	0.06 3 Compound: camptothecin	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 19863101]
HepG2	IC₅₀	0.09 6 Compound: 1	Cytotoxicity in HepG2-T14 cancer cell line Cytotoxicity in HepG2-T14 cancer cell line	10.1016/S0960-894X(01)80158-X
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR3 cells by SRB assay Antiproliferative activity against human OVCAR3 cells by SRB assay	[PMID: 21710981]
OVCAR-3	GI₅₀	0.22 3 Compound: 2	Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
HepG2	IC₅₀	0.11 3 Compound: 1; CPT	Antiproliferative activity against human HepG2 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
HepG2	IC₅₀	0.13 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells after 4 days by MTT assay Cytotoxicity against human HepG2 cells after 4 days by MTT assay	[PMID: 18554906]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR3 cells after 48 hrs Antiproliferative activity against human OVCAR3 cells after 48 hrs	[PMID: 27070999]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant mouse P388 cells after 4 days by MTT method Cytotoxicity against camptothecin-resistant mouse P388 cells after 4 days by MTT method	[PMID: 19303306]
HepG2	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against mouse CPT45-resistant topoisomerase 1-deficient P388 cells after 4 days by MTT assay Cytotoxicity against mouse CPT45-resistant topoisomerase 1-deficient P388 cells after 4 days by MTT assay	[PMID: 18676151]
HepG2	IC₅₀	0.2 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
HepG2	IC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24041234]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant mouse P388 cells by MTT method Cytotoxicity against camptothecin-resistant mouse P388 cells by MTT method	[PMID: 18771930]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT method Cytotoxicity against mouse P388 cells after 4 days by MTT method	[PMID: 19303306]
HepG2	IC₅₀	0.3 3 Compound: camptothecin	Cytotoxicity against human HEPG2 cells by MTT assay Cytotoxicity against human HEPG2 cells by MTT assay	[PMID: 18841903]
HepG2	IC₅₀	0.37 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30055465]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT assay Cytotoxicity against mouse P388 cells after 4 days by MTT assay	[PMID: 19299037]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells by MTT method Cytotoxicity against mouse P388 cells by MTT method	[PMID: 18771930]
HepG2	IC₅₀	0.4 3 Compound: CPT	Antitumor activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
P388	IC₅₀	0.009 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT assay Cytotoxicity against mouse P388 cells after 4 days by MTT assay	[PMID: 18676151]
HepG2	IC₅₀	0.43 3 Compound: Camp	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
HepG2	IC₅₀	0.5 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 30007563]
P388	IC₅₀	0.014 3 Compound: CPT	Cytotoxicity against mouse P388 cells after MTT assay Cytotoxicity against mouse P388 cells after MTT assay	[PMID: 18829334]
HepG2	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
P388	IC₅₀	0.014 3 Compound: CPT	Cytotoxicity against mouse P388 cells by MTT method Cytotoxicity against mouse P388 cells by MTT method	[PMID: 19012996]
HepG2	IC₅₀	0.66 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30600208]
P388	IC₅₀	32.1 1 Compound: camptothecin	Cytotoxicity against mouse P388 cells after 72 hrs Cytotoxicity against mouse P388 cells after 72 hrs	[PMID: 17624792]
P388	IC₅₀	4.74 14 Compound: 1a	Tested in vitro for the inhibition of P388 (mouse leukemia) cell line by MTT assay Tested in vitro for the inhibition of P388 (mouse leukemia) cell line by MTT assay	[PMID: 7932525]
HepG2	IC₅₀	1.36 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30125725]
HepG2	IC₅₀	1.36 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells assessed reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 38107170]
P388CPT45	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant and TOP1 deficient mouse P388/CPT45 cells after MTT assay Cytotoxicity against camptothecin-resistant and TOP1 deficient mouse P388/CPT45 cells after MTT assay	[PMID: 18829334]
P388CPT45	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against mouse P388/CPT45 cells after 4 days by MTT assay Cytotoxicity against mouse P388/CPT45 cells after 4 days by MTT assay	[PMID: 19299037]
HepG2	IC₅₀	1.52 3 Compound: 1; CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27416553]
PANC-1	IC₅₀	0.09 3 Compound: CPT	Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay	[PMID: 30017114]
HepG2	IC₅₀	1.8 3 Compound: CPT	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
PANC-1	IC₅₀	0.18 3 Compound: CPT	Cytotoxicity against human PANC1 cells after 48 hrs by XTT assay Cytotoxicity against human PANC1 cells after 48 hrs by XTT assay	[PMID: 30017114]
HepG2	IC₅₀	13.2 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30025344]
PANC-1	GI₅₀	6.29 3 Compound: 1, CPT	Cytotoxicity against human PANC1 cells incubated for 72 hrs by MTT assay Cytotoxicity against human PANC1 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HepG2	IC₅₀	13.2 3 Compound: Camptothecin	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by alamarBlue assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by alamarBlue assay	[PMID: 38107170]
HepG2	IC₅₀	29.81 3 Compound: Camptothecin	Growth inhibition of human HepG2 cells after 72 hrs by MTT assay Growth inhibition of human HepG2 cells after 72 hrs by MTT assay	[PMID: 27344492]
PBMC	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human PBMC assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human PBMC assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
PC-3	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human PC3 cells incubated for 72 hrs by MTT assay Cytotoxicity against human PC3 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
HepG2	IC₅₀	3.5 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
PC-3	IC₅₀	> 40 3 Compound: Camp	Induction of apoptosis in human PC3 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human PC3 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
HepG2	IC₅₀	32.3 3 Compound: Camptothecin	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 23562244]
HepG2	IC₅₀	33.16 1 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth	[PMID: 37806498]
PC-3	IC₅₀	0.01 3 Compound: Camptothecin	Growth inhibition of human PC3 cells after 72 hrs by MTT assay Growth inhibition of human PC3 cells after 72 hrs by MTT assay	[PMID: 24180210]
HepG2	IC₅₀	4.37 3 Compound: Camp	Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
PC-3	IC₅₀	0.03 3 Compound: Camptothecin	Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HepG2	IC₅₀	4.79 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30685528]
PC-3	GI₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21115210]
HepG2	IC₅₀	4.92 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28511910]
PC-3	GI₅₀	0.09 3 Compound: CPT	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 20662543]
PC-3	GI₅₀	0.09 3 Compound: 1, camptothecin	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 18180162]
HepG2	IC₅₀	455 1 Compound: camptothecin	Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay	[PMID: 19655762]
HepG2	IC₅₀	5.69 3 Compound: CPT	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
PC-3	IC₅₀	0.1 3 Compound: CPT	Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay	[PMID: 25799376]
PC-3	IC₅₀	0.4 3 Compound: Camp	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
HepG2	IC₅₀	6.08 3 Compound: CPT	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30125725]
HepG2	IC₅₀	6.3 1 Compound: 1	Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]thymidine into cellular DNA of human hepatocellular cells (HepG2) Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]thymidine into cellular DNA of human hepatocellular cells (HepG2)	[PMID: 10479293]
PC-3	GI₅₀	0.48 3 Compound: 1	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21388138]
PC-3	GI₅₀	0.7 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay	[PMID: 19715319]
HepG2	IC₅₀	6.4 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 22326393]
PC-3	IC₅₀	1.2 3 Compound: Camptothecin	Antiproliferative activity against human PC3 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
HepG2	IC₅₀	7.25 1 Compound: 1; CPT	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 38421819]
PC-3	IC₅₀	1.2 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 24041234]
HepG2	IC₅₀	7.25 14 Compound: 1; CPT	Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 38421819]
PC-3	IC₅₀	1.4 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay	[PMID: 19715319]
HepG2	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 22409771]
PC-3	IC₅₀	12 1 Compound: 1a	Cytotoxicity against human PC3 cells after 72 hrs by alamar blue assay Cytotoxicity against human PC3 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
HepG2	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
HepG2	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
PC-3	IC₅₀	16.24 3 Compound: CPT	Cytotoxicity against human PC3 after 48 hrs by SRB assay Cytotoxicity against human PC3 after 48 hrs by SRB assay	[PMID: 21044847]
PC-3	ED₅₀	16.7 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human PC3 cells by sulforhodamine B assay Cytotoxicity against human PC3 cells by sulforhodamine B assay	[PMID: 17350834]
Hs 683	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human Hs683 cells after 72 hrs by MTT assay Growth inhibition of human Hs683 cells after 72 hrs by MTT assay	[PMID: 24180210]
PC-3	IC₅₀	18.24 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30109008]
Huh-7	GI₅₀	0.006 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 29705710]
PC-3	IC₅₀	2.4 3 Compound: CPT	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
PC-3	IC₅₀	2.5 3 Compound: CPT	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 26226379]
Huh-7	GI₅₀	0.099 3 Compound: 1	Growth inhibition of human HuH7 cells after 72 hrs by MTT assay Growth inhibition of human HuH7 cells after 72 hrs by MTT assay	[PMID: 30336023]
Huh-7	IC₅₀	0.0023 3 Compound: CPT	Cytotoxicity against human HuH7 cells by MTT assay Cytotoxicity against human HuH7 cells by MTT assay	[PMID: 30543429]
PC-3	IC₅₀	6.96 3 Compound: Camptothecin	Antiproliferative activity against human PC3 cells by MTT assay Antiproliferative activity against human PC3 cells by MTT assay	[PMID: 29131616]
PC-3	IC₅₀	78 1 Compound: CPT	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 24900725]
Huh-7	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 25247770]
Huh-7	IC₅₀	0.06 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 3 days by SRB assay Cytotoxicity against human HuH7 cells after 3 days by SRB assay	[PMID: 23142674]
PC-3M	IC₅₀	0.19 3 Compound: Camptothecin	Anticancer activity in human PC-3M cells expressing PTB/GFP fusion protein assessed as perinucleolar compartment disassembly and measured after 24 hrs by Hoechst 33342 staining based microscopic method Anticancer activity in human PC-3M cells expressing PTB/GFP fusion protein assessed as perinucleolar compartment disassembly and measured after 24 hrs by Hoechst 33342 staining based microscopic method	[PMID: 35696646]
Huh-7	IC₅₀	0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay	10.1039/C4MD00306C
PC-3M	IC₅₀	0.48 3 Compound: Camptothecin	Cytotoxicity against human PC-3M cells expressing PTB/GFP fusion protein assessed as reduction in ATP level and measured after 24 to 48 hrs by ATPlite luminescence assay Cytotoxicity against human PC-3M cells expressing PTB/GFP fusion protein assessed as reduction in ATP level and measured after 24 to 48 hrs by ATPlite luminescence assay	[PMID: 35696646]
QG-56	IC₅₀	4.63 14 Compound: 1a	Tested in vitro for the inhibition of QG-56 (human lung squamous cell carcinoma) cell line by MTT assay Tested in vitro for the inhibition of QG-56 (human lung squamous cell carcinoma) cell line by MTT assay	[PMID: 7932525]
Huh-7	IC₅₀	0.15 3 Compound: CPT	Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
Huh-7	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human HuH7 cells after 48 hrs by CCK8 assay Cytotoxicity against human HuH7 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
Raji	IC₅₀	1 3 Compound: camptothecin	Cytotoxicity against human Raji cells by MTT assay Cytotoxicity against human Raji cells by MTT assay	[PMID: 20329739]
Raji	IC₅₀	3.27 3 Compound: Camptothecin	Cytotoxicity against human Raji cells after 48 hrs by MTT assay Cytotoxicity against human Raji cells after 48 hrs by MTT assay	[PMID: 30109008]
Huh-7	IC₅₀	113.1 3 Compound: CPT	Antiproliferative activity against human Huh-7 cells incubated for 24 hrs by CCK-8 assay Antiproliferative activity against human Huh-7 cells incubated for 24 hrs by CCK-8 assay	[PMID: 38278140]
Huh-7	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 22409771]
RD	IC₅₀	1.24 3 Compound: CPT	Cytotoxicity against human TE32 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human TE32 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
Huh-7	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human Huh-7 cells measured after 72 hrs by MTT assay Antiproliferative activity against human Huh-7 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
RD	IC₅₀	1.24 3 Compound: CPT	Cytotoxicity against human TE32 cells measured after 72 hrs by MTT assay Cytotoxicity against human TE32 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
Huh-7	IC₅₀	<= 0.1 3 Compound: CPT	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
RD	IC₅₀	1.72 3 Compound: CPT	Cytotoxicity against against human RD cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human RD cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
RD	IC₅₀	4.47 3 Compound: Camptothecin	Cytotoxicity against human TE-32 cells after 72 hrs ny MTT assay Cytotoxicity against human TE-32 cells after 72 hrs ny MTT assay	[PMID: 23974020]
IGROV-1	IC₅₀	0.012 3 Compound: 1, CPT	Cytotoxicity against human IGROV1 cells after 72 hrs Cytotoxicity against human IGROV1 cells after 72 hrs	[PMID: 18419110]
IGROV-1	IC₅₀	1.65 3 Compound: 1, CPT	Cytotoxicity against human IGROV1 cells after 1 hr Cytotoxicity against human IGROV1 cells after 1 hr	[PMID: 18419110]
RD	IC₅₀	4.49 3 Compound: Camptothecin	Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
RKO	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human RKO cells measured after 72 hrs by MTT assay Antiproliferative activity against human RKO cells measured after 72 hrs by MTT assay	[PMID: 35462164]
RKO	IC₅₀	0.0617 3 Compound: CPT	Antiproliferative activity against human RKO cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human RKO cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
IMR-32	IC₅₀	0.08 3 Compound: Camptothecin	Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
IMR-32	IC₅₀	2.21 1 Compound: Camptothecin	Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptors Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptors	[PMID: 12617894]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT method Cytotoxicity against human RPMI8402 cells after 4 days by MTT method	[PMID: 19303306]
IMR-90	IC₅₀	0.43 3 Compound: Camptothecin	Cytotoxicity against human IMR90 cells incubated for 3 days by SRB assay Cytotoxicity against human IMR90 cells incubated for 3 days by SRB assay	[PMID: 22863526]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay	[PMID: 19299037]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells by MTT method Cytotoxicity against human RPMI8402 cells by MTT method	[PMID: 18771930]
RPMI 8402	IC₅₀	0.005 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay	[PMID: 18676151]
RPMI 8402	IC₅₀	0.005 3 Compound: Camptothecin	Cytotoxic activity against human lymphoblast tumor cell line RPMI8402 after 4 days of treatment Cytotoxic activity against human lymphoblast tumor cell line RPMI8402 after 4 days of treatment	[PMID: 12747798]
RPMI 8402	IC₅₀	0.006 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after MTT assay Cytotoxicity against human RPMI8402 cells after MTT assay	[PMID: 18829334]
RPMI-7951	IC₅₀	0.22 3 Compound: CPT	Cytotoxicity against human RPMI7951 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human RPMI7951 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32435422]
RPMI-8226	IC₅₀	0.006 3 Compound: CPT	Cytotoxicity against human RPMI8226 cells by MTT method Cytotoxicity against human RPMI8226 cells by MTT method	[PMID: 19012996]
RPMI-8226	IC₅₀	2.05 6 Compound: Camptothecin	Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay	[PMID: 25867737]
SAOS-2	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human Saos2 cells incubated for 72 hrs by MTT assay Cytotoxicity against human Saos2 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
SAS	GI₅₀	6 3 Compound: CPT	Cytotoxicity against human SAS cells after 48 hrs by MTT assay Cytotoxicity against human SAS cells after 48 hrs by MTT assay	[PMID: 20662543]
SAS	GI₅₀	6 3 Compound: 1, camptothecin	Antiproliferative activity against human SAS cells after 48 hrs by MTT assay Antiproliferative activity against human SAS cells after 48 hrs by MTT assay	[PMID: 18180162]
SAS	IC₅₀	6 3 Compound: CPT	Antiproliferative activity against human SAS cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SAS cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
SF-268	IC₅₀	0.04 3 Compound: Camptothecin	Cytotoxicity against human SF268 cells after 72 hrs by MTS assay Cytotoxicity against human SF268 cells after 72 hrs by MTS assay	[PMID: 21513293]
Jurkat	GI₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
SF-268	EC₅₀	0.059 3 Compound: camptothecin	Cytotoxicity against human SF-268 after 3 days by SRB assay Cytotoxicity against human SF-268 after 3 days by SRB assay	[PMID: 15730238]
Jurkat	GI₅₀	0.09 3 Compound: 1	Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay	[PMID: 21388138]
SF-268	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SF268 cells incubated for 3 days by SRB assay Cytotoxicity against human SF268 cells incubated for 3 days by SRB assay	[PMID: 22863526]
Jurkat	IC₅₀	0.026 3 Compound: Camptothecin	Cytotoxicity against human Jurkat cells after 2 days by MTT assay Cytotoxicity against human Jurkat cells after 2 days by MTT assay	[PMID: 22325897]
SF-268	GI₅₀	0.19 3 Compound: CPT	Cytotoxicity against human SF268 cells after 72 hrs by XTT assay Cytotoxicity against human SF268 cells after 72 hrs by XTT assay	[PMID: 20591678]
Jurkat	IC₅₀	0.085 3 Compound: CPT	Anticancer activity against human Jurkat cells after 48 hrs by MTT assay Anticancer activity against human Jurkat cells after 48 hrs by MTT assay	[PMID: 26890120]
SF-539	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human SF539 cells after 48 hrs by SRB assay Cytotoxicity against human SF539 cells after 48 hrs by SRB assay	[PMID: 28418653]
Jurkat	IC₅₀	0.1 3 Compound: 1; CPT	Anticancer activity against human Jurkat cells incubated for 48 hrs by MTT assay Anticancer activity against human Jurkat cells incubated for 48 hrs by MTT assay	[PMID: 34175539]
SF-539	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human SF539 cells after 48 hrs by SRB assay Growth inhibition of human SF539 cells after 48 hrs by SRB assay	[PMID: 24800942]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells after 48 hrs by SRB assay Cytotoxicity against human SF539 cells after 48 hrs by SRB assay	[PMID: 21823606]
Jurkat	IC₅₀	0.11 3 Compound: CPT, Camptothecin	Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay	[PMID: 24980118]
Jurkat	IC₅₀	1.4 1 Compound: camptothecin	Growth inhibition of human Jurkat cells after 96 hrs Growth inhibition of human Jurkat cells after 96 hrs	[PMID: 18061452]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells by SRB assay Cytotoxicity against human SF539 cells by SRB assay	[PMID: 24502276]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells by SRB assay Antiproliferative activity against human SF539 cells by SRB assay	[PMID: 21710981]
Jurkat	IC₅₀	22 3 Compound: CPT	Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 48 hrs by MTT assay	[PMID: 30853330]
SF-539	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
Jurkat	IC₅₀	22 3 Compound: Camptophecin	Cytotoxicity against human Jurkat cells Cytotoxicity against human Jurkat cells	[PMID: 33421712]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells after 48 hrs Antiproliferative activity against human SF539 cells after 48 hrs	[PMID: 27070999]
Jurkat	IC₅₀	5.6 1 Compound: Camptothecin	Inhibitory activity against Jurkat human leukemia cells Inhibitory activity against Jurkat human leukemia cells	[PMID: 11384245]
Jurkat	IC₅₀	5.6 1 Compound: Camptothecin	Growth inhibitory activity against human Jurkat leukemia cell line (JLC) Growth inhibitory activity against human Jurkat leukemia cell line (JLC)	[PMID: 12620081]
Sf9	IC₅₀	0.025 3 Compound: CPT	Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis	[PMID: 30897325]
Jurkat	IC₅₀	51.5 3 Compound: CPT	Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay Antiproliferative activity against human Jurkat cells assessed as reduction in cell proliferation measured after 24 hrs by MTT assay	[PMID: 30853330]
SGC-7901	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
SGC-7901	IC₅₀	5.8 3 Compound: CPT	Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
K562	GI₅₀	0.06 3 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by XTT assay Cytotoxicity against human K562 cells after 72 hrs by XTT assay	[PMID: 20591678]
SH-SY5Y	IC₅₀	> 100 3 Compound: Camptothecin	Growth inhibition of human SH-SY5Y cells after 72 hrs by MTT assay Growth inhibition of human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 27344492]
K562	GI₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 21115210]
SH-SY5Y	IC₅₀	0.61 3 Compound: CPT	Cytotoxicity against human SH-SY5Y cells expressing low level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells expressing low level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
K562	GI₅₀	54.3 14 Compound: 1; CPT	Growth inhibition of human K562 cells incubated for 72 hrs by MTT assay Growth inhibition of human K562 cells incubated for 72 hrs by MTT assay	[PMID: 38421819]
SiHa	GI₅₀	0.55 3 Compound: Camptothecin	Antiproliferative activity against human SiHa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human SiHa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
K562	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 24360564]
SK-BR-3	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human SKBR3 cells after 3 days by SRB assay Cytotoxicity against human SKBR3 cells after 3 days by SRB assay	[PMID: 23142674]
SK-BR-3	GI₅₀	0.15 3 Compound: Camptothecin	Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay	[PMID: 20438092]
K562	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against human K562 cells by MTT assay Cytotoxicity against human K562 cells by MTT assay	[PMID: 36924947]
SK-BR-3	IC₅₀	0.21 3 Compound: CPT	Cytotoxicity against HER-positive human SK-BR-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human SK-BR-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
K562	IC₅₀	0.04 3 Compound: camptothecin	Growth inhibition of K562 cells by XTT assay after 5 days Growth inhibition of K562 cells by XTT assay after 5 days	[PMID: 17411092]
SK-HEP1	IC₅₀	0.9 3 Compound: CPT	Antiproliferative activity against human SKHEP1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human SKHEP1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
K562	IC₅₀	0.04 3 Compound: camptothecin	Cytotoxicity against human K562 cells after 5 days by XTT assay Cytotoxicity against human K562 cells after 5 days by XTT assay	[PMID: 18076140]
SK-HEP1	IC₅₀	0.96 3 Compound: CPT	Cytotoxicity against human SKHEP1 cells after 72 hrs by MTT assay Cytotoxicity against human SKHEP1 cells after 72 hrs by MTT assay	[PMID: 26226379]
K562	IC₅₀	0.07 3 Compound: CPT	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 30055465]
K562	IC₅₀	0.08 3 Compound: CPT	Antiproliferative activity against human K562 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
SK-MEL	GI₅₀	0.047 3 Compound: 1	Cytotoxicity against human SK-MEL cells after 72 hrs by MTT assay Cytotoxicity against human SK-MEL cells after 72 hrs by MTT assay	[PMID: 21388138]
SK-MEL-2	IC₅₀	0.075 3 Compound: CPT, campothecin	Cytotoxicity against human SK-MEL-2 cells by SRB assay Cytotoxicity against human SK-MEL-2 cells by SRB assay	[PMID: 17827007]
K562	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 4 days by ELISA reader assay Cytotoxicity against human K562 cells after 4 days by ELISA reader assay	[PMID: 19939682]
SK-MEL-2	IC₅₀	0.165 3 Compound: camptothecin	Cytotoxicity against human SK-MEL-2 cells after 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs	[PMID: 17673337]
K562	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human K562 cells in presence of 10% fetal bovine serum Cytotoxicity against human K562 cells in presence of 10% fetal bovine serum	[PMID: 20188578]
SK-MEL-2	IC₅₀	6.88 6 Compound: CPT	Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay	[PMID: 21684168]
K562	IC₅₀	0.09 3 Compound: Camp	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
SK-MEL-2	IC₅₀	7.86 3 Compound: CPT	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by MTT assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by MTT assay	[PMID: 21873069]
K562	IC₅₀	0.13 3 Compound: Camptothecin	Antitumor activity against human K562 cells incubated for 48 hrs by MTT assay Antitumor activity against human K562 cells incubated for 48 hrs by MTT assay	[PMID: 25590864]
SK-MEL-24	IC₅₀	0.46 3 Compound: CPT	Cytotoxicity against human SK-MEL-24 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human SK-MEL-24 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32435422]
K562	IC₅₀	0.32 3 Compound: CPT	Cytotoxicity against human K562 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
K562	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 24 to 72 hrs by MTT assay Cytotoxicity against human K562 cells after 24 to 72 hrs by MTT assay	[PMID: 24303808]
SK-MEL-28	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay	[PMID: 24180210]
K562	IC₅₀	0.58 3 Compound: Camptothecin	Antitumor activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
SK-MEL-28	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human SK-MEL-28 cells by MTT assay Antiproliferative activity against human SK-MEL-28 cells by MTT assay	[PMID: 17254669]
K562	IC₅₀	0.59 3 Compound: Camptothecin	Cytotoxicity against human K562 cells by MTT assay Cytotoxicity against human K562 cells by MTT assay	[PMID: 21115246]
SK-MEL-28	CC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay	[PMID: 22884523]
K562	IC₅₀	0.711 3 Compound: Camp	Induction of apoptosis in human K562 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human K562 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
SK-MEL-28	CC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay	[PMID: 22047799]
SK-MEL-28	IC₅₀	2.26 3 Compound: CPT	Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
K562	IC₅₀	1.18 3 Compound: Camptothecin	Cytotoxicity against human K562 cells after 2 days Cytotoxicity against human K562 cells after 2 days	[PMID: 22318164]
K562	IC₅₀	1.4 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human K562 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human K562 cells after 48 hrs by SRB assay	[PMID: 19715319]
SK-MES-1	IC₅₀	0.01 3 Compound: CPT	Antiproliferative activity against human SKMES1 cells by MTT assay Antiproliferative activity against human SKMES1 cells by MTT assay	[PMID: 17254669]
SK-MES-1	CC₅₀	0.03 3 Compound: Camptothecin	Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay	[PMID: 22047799]
K562	IC₅₀	2 1 Compound: 1; CPT	Cytotoxicity against human K562 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 38421819]
SK-MES-1	CC₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay	[PMID: 22884523]
K562	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against human imitinib-resistant K562 cells by MTT assay Cytotoxicity against human imitinib-resistant K562 cells by MTT assay	[PMID: 20329739]
SK-OV-3	IC₅₀	0.014 3 Compound: camptothecin	Cytotoxicity against human SK-OV3 cells after 48 hrs Cytotoxicity against human SK-OV3 cells after 48 hrs	[PMID: 17673337]
K562	IC₅₀	2 1 Compound: camptothecin	Cytotoxicity against imatinib-resistant human K562 cells after 72 hrs by MTT assay Cytotoxicity against imatinib-resistant human K562 cells after 72 hrs by MTT assay	[PMID: 20590148]
SK-OV-3	IC₅₀	0.051 3 Compound: Camptothecin	Inhibitory concentration the viability of SKOV 3 cell population by 50%. Inhibitory concentration the viability of SKOV 3 cell population by 50%.	[PMID: 9003520]
K562	IC₅₀	2.69 3 Compound: Camptothecin	Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
SK-OV-3	IC₅₀	1.54 6 Compound: CPT	Cytotoxicity against human SKOV3 cells by sulforhodamine B assay Cytotoxicity against human SKOV3 cells by sulforhodamine B assay	[PMID: 21684168]
K562	IC₅₀	31 1 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 24900725]
SK-OV-3	IC₅₀	2.544 3 Compound: CPT	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 21873069]
K562	IC₅₀	5.37 3 Compound: CPT	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 25599951]
SK-OV-3	IC₅₀	2.56 3 Compound: Camptothecin	Antitumor activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
K562	IC₅₀	57 1 Compound: CPT	Antiproliferative activity measured against K562adr leukemia cells. Antiproliferative activity measured against K562adr leukemia cells.	[PMID: 9876111]
SK-OV-3	IC₅₀	3.82 3 Compound: CPT	Cytotoxicity against HER-positive human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
K562	IC₅₀	< 0.003 3 Compound: CPT	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 26226379]
SK-OV-3	IC₅₀	37 1 Compound: 1	Cytotoxicity was determined in vitro in SK-OV-3 cells (ovarian) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in SK-OV-3 cells (ovarian) of human tumor cell lines by using MTT assay	[PMID: 7853331]
K562	IC₅₀	< 0.003 3 Compound: CPT	Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
SK-OV-3	IC₅₀	4.86 3 Compound: Camptothecin	Antitumor activity against taxol-resistant human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against taxol-resistant human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
SK-OV-3	IC₅₀	5.5 1 Compound: CPT	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
KB	CC₅₀	0.006 3 Compound: Camptothecin	Compound concentration required to reduce the exponential growth of KB cells by 50% Compound concentration required to reduce the exponential growth of KB cells by 50%	[PMID: 9767632]
SK-OV-3	IC₅₀	5.5 1 Compound: CPT	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
KB	EC₅₀	0.0036 3 Compound: camptothecin	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 17552563]
SK-OV-3	IC₅₀	5.5 1 Compound: I; CPT	Antiproliferative activity against human SKOV3 cells incubated for 48 hrs by CCK8 assay Antiproliferative activity against human SKOV3 cells incubated for 48 hrs by CCK8 assay	[PMID: 31229877]
SK-OV-3	IC₅₀	5.5 1 Compound: CPT	Antiproliferative activity against human SKOV3 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human SKOV3 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
KB	EC₅₀	0.01 6 Compound: camptothecin	Cytotoxicity against human KB cells after 72 hrs by MTS method Cytotoxicity against human KB cells after 72 hrs by MTS method	[PMID: 11858737]
SK-OV-3	IC₅₀	5.5 1 Compound: Camptothecin	Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
KB	EC₅₀	0.01 6 Compound: camptothecin	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 15270571]
SK-OV-3	IC₅₀	5.5 3 Compound: I; CPT	Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
KB	ED₅₀	2.3 6 Compound: Camptothecin	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 7130986]
SK-VLB	IC₅₀	0.053 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of SKVLB cell population by 50%. Inhibitory concentration that reduced the viability of SKVLB cell population by 50%.	[PMID: 9003520]
KB	ED₅₀	20.9 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human KB cells by sulforhodamine B assay Cytotoxicity against human KB cells by sulforhodamine B assay	[PMID: 17350834]
SK-VLB	IC₅₀	41 1 Compound: 1	Cytotoxicity was determined in vitro in SKVLB cells(ovarian with upregulated MDRp-glycoprotein) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in SKVLB cells(ovarian with upregulated MDRp-glycoprotein) of human tumor cell lines by using MTT assay	[PMID: 7853331]
KB	ED₅₀	22 1 Compound: camptothecin	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 15043407]
KB	IC₅₀	0.003 3 Compound: 1, CPT	Cytotoxicity against human KB cells after 4 days by MTT assay Cytotoxicity against human KB cells after 4 days by MTT assay	[PMID: 18554906]
SMMC-7721	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
KB	IC₅₀	0.008 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of KB cell population by 50%. Inhibitory concentration that reduced the viability of KB cell population by 50%.	[PMID: 9003520]
SMMC-7721	IC₅₀	0.003 3 Compound: camptothecin	Cytotoxicity against human SMMC7721 cells after 48 hrs by SRB assay Cytotoxicity against human SMMC7721 cells after 48 hrs by SRB assay	[PMID: 21973054]
SMMC-7721	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human SMMC7721 after 48 hrs by SRB assay Cytotoxicity against human SMMC7721 after 48 hrs by SRB assay	[PMID: 21044847]
KB	IC₅₀	0.009 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against KB (human epidermoid carcinoma of the nasopharynx) In vitro cytotoxicity against KB (human epidermoid carcinoma of the nasopharynx)	[PMID: 14552770]
SMMC-7721	IC₅₀	0.45 3 Compound: CPT; 1	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 30509782]
KB	IC₅₀	0.01 6 Compound: 1	Cytotoxicity in KB cancer cell line Cytotoxicity in KB cancer cell line	10.1016/S0960-894X(01)80158-X
KB	IC₅₀	0.01 6 Compound: Camptothecin	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 8759170]
SMMC-7721	IC₅₀	1.08 3 Compound: CPT	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 30125725]
KB	IC₅₀	0.02 3 Compound: CPT	Concentration required to inhibit cell proliferation in KBV-1 tumor cell line; overexpress MDR1 Concentration required to inhibit cell proliferation in KBV-1 tumor cell line; overexpress MDR1	[PMID: 15482929]
SN12C	GI₅₀	0.02 3 Compound: 18	Cytotoxicity against human SN12C cells after 48 hrs by SRB assay Cytotoxicity against human SN12C cells after 48 hrs by SRB assay	[PMID: 28418653]
KB	IC₅₀	0.02 3 Compound: Camptothecin	Antiproliferative activity against human KB cells by SRB assay Antiproliferative activity against human KB cells by SRB assay	[PMID: 24200393]
SN12C	GI₅₀	0.02 3 Compound: 1	Growth inhibition of human SN12C cells after 48 hrs by SRB assay Growth inhibition of human SN12C cells after 48 hrs by SRB assay	[PMID: 24800942]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells after 48 hrs by SRB assay Cytotoxicity against human SN12C cells after 48 hrs by SRB assay	[PMID: 21823606]
KB	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against drug-resistant tumor cell line KBV20C. Antiproliferative activity against drug-resistant tumor cell line KBV20C.	[PMID: 10411476]
KB	IC₅₀	0.035 3 Compound: Camptothecin	Antiproliferative activity against drug-resistant tumor cell line KB7D. Antiproliferative activity against drug-resistant tumor cell line KB7D.	[PMID: 10411476]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells by SRB assay Cytotoxicity against human SN12C cells by SRB assay	[PMID: 24502276]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells by SRB assay Antiproliferative activity against human SN12C cells by SRB assay	[PMID: 21710981]
KB	IC₅₀	0.037 3 Compound: 1	Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B colorimetric assay Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B colorimetric assay	[PMID: 26994847]
SN12C	GI₅₀	0.02 3 Compound: 2	Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
KB	IC₅₀	0.037 3 Compound: 1, CPT	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 25003995]
KB	IC₅₀	0.04 3 Compound: Camptothecin	Antiproliferative activity against drug-resistant tumor cell line KBwt. Antiproliferative activity against drug-resistant tumor cell line KBwt.	[PMID: 10411476]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells after 48 hrs Antiproliferative activity against human SN12C cells after 48 hrs	[PMID: 27070999]
SNU-475	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human SNU475 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human SNU475 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
KB	IC₅₀	0.04 6 Compound: 1	Cytotoxicity in KB VP-16 R cancer cell line Cytotoxicity in KB VP-16 R cancer cell line	10.1016/S0960-894X(01)80158-X
KB	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against drug-resistant tumor cell line KBMDR. Antiproliferative activity against drug-resistant tumor cell line KBMDR.	[PMID: 10411476]
SNU-638	IC₅₀	0.098 3 Compound: CPT	Cytotoxicity against human SNU638 cells by MTT assay Cytotoxicity against human SNU638 cells by MTT assay	[PMID: 21353568]
SNU-638	IC₅₀	0.098 3 Compound: camptothecin	Cytotoxicity against human SNU638 cells by SRB assay Cytotoxicity against human SNU638 cells by SRB assay	[PMID: 17498951]
KB	IC₅₀	0.121 3 Compound: 1, CPT	Cytotoxicity against human KB cells by SRB assay Cytotoxicity against human KB cells by SRB assay	[PMID: 23102893]
KB	IC₅₀	1.04 3 Compound: Camptothecin	Antiproliferative activity against drug-resistant tumor cell line KBCamp. Antiproliferative activity against drug-resistant tumor cell line KBCamp.	[PMID: 10411476]
SNU-638	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against human SNU638 cells by MTT assay Cytotoxicity against human SNU638 cells by MTT assay	[PMID: 23608763]
Splenocyte	CC₅₀	0.62 3 Compound: CPT	Cytotoxicity against BALB/c mouse splenocytes assessed as cell viability after 48 hrs by alamar blue assay Cytotoxicity against BALB/c mouse splenocytes assessed as cell viability after 48 hrs by alamar blue assay	[PMID: 27639365]
KB	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human KB cells by SRB staining-based fluorescence cytometry Cytotoxicity against human KB cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
SU-DHL-2	IC₅₀	0.94 3 Compound: Camptothecin	Antitumor activity against human SUDHL2 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human SUDHL2 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
KB	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human KB cells by MTT assay Cytotoxicity against human KB cells by MTT assay	[PMID: 11858760]
KB	IC₅₀	38 1 Compound: camptothecin	Cytotoxicity against human KB cells after 72 hrs by MTS assay Cytotoxicity against human KB cells after 72 hrs by MTS assay	[PMID: 19655762]
SW1573	GI₅₀	0.21 3 Compound: CPT	Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
SW1573	GI₅₀	0.25 3 Compound: Camptothecin	Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay	[PMID: 23831507]
KB	IC₅₀	50 1 Compound: 1	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 28927790]
KB	IC₅₀	50 1 Compound: 1; CPT	Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
SW1990	IC₅₀	0.2 3 Compound: CPT	Antitumor activity against human SW1990 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human SW1990 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
KB	IC₅₀	8.8 1 Compound: CPT	Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay	[PMID: 22698783]
SW480	IC₅₀	0.21 3 Compound: Camptothecin	Antiproliferation activity against human SW480 cells assessed as reduction in cell viability measured after 72 hours by MTT assay Antiproliferation activity against human SW480 cells assessed as reduction in cell viability measured after 72 hours by MTT assay	[PMID: 32201190]
KB	IC₅₀	< 0.005 6 Compound: 1 Camptothecin	In vitro cytotoxicity against KB cell line (human epidermoid carcinoma of the nasopharynx) using MTT assay In vitro cytotoxicity against KB cell line (human epidermoid carcinoma of the nasopharynx) using MTT assay	[PMID: 15225719]
SW480	IC₅₀	0.29 3 Compound: CPT; 1	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 30509782]
SW-620	EC₅₀	0.0021 3 Compound: Cpt, camptothecin	Antiproliferative activity against human SW620 cells by soft agar assay Antiproliferative activity against human SW620 cells by soft agar assay	[PMID: 17287122]
KB	IC₅₀	< 0.013 3 Compound: CPT	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 20392545]
SW626	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human SW626 cells by MTT assay Cytotoxicity against human SW626 cells by MTT assay	[PMID: 11858760]
SW948	IC₅₀	0.16 3 Compound: CPT	Antiproliferative activity against human SW948 cells after 3 days by XTT assay Antiproliferative activity against human SW948 cells after 3 days by XTT assay	[PMID: 19691293]
T-24	IC₅₀	0.006 3 Compound: camptothecin	Growth inhibition of human T24 cells by neutral red assay Growth inhibition of human T24 cells by neutral red assay	[PMID: 17204425]
T-24	IC₅₀	3.09 3 Compound: CPT	Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
KB 3-1	IC₅₀	0.01 3 Compound: CPT	Concentration required to inhibit cell proliferation in KB3-1 tumor cell line Concentration required to inhibit cell proliferation in KB3-1 tumor cell line	[PMID: 15482929]
T-24	IC₅₀	6.8 3 Compound: CPT	Antiproliferative activity against human T24 cells after 48 hrs by MTT assay Antiproliferative activity against human T24 cells after 48 hrs by MTT assay	[PMID: 30685528]
KB 3-1	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human KB3-1 cells after 4 days by MTT assay Cytotoxicity against human KB3-1 cells after 4 days by MTT assay	[PMID: 18676151]
T-24	IC₅₀	88 1 Compound: 1, CPT, NSC-100880	Cytotoxicity against human chemo-resistant T24 cells by WST assay Cytotoxicity against human chemo-resistant T24 cells by WST assay	[PMID: 23578545]
T-24	IC₅₀	88 1 Compound: CPT	Cytotoxicity against T24 tumor cell line determined by WST-1 assay Cytotoxicity against T24 tumor cell line determined by WST-1 assay	[PMID: 10841808]
KB 3-1	IC₅₀	0.015 3 Compound: CPT	Cytotoxicity against human KB3-1 cells by MTT method Cytotoxicity against human KB3-1 cells by MTT method	[PMID: 18771930]
KB 3-1	IC₅₀	0.02 3 Compound: CPT	Concentration required to inhibit cell proliferation in KBH5.0 tumor cell line; overexpress BCRP Concentration required to inhibit cell proliferation in KBH5.0 tumor cell line; overexpress BCRP	[PMID: 15482929]
T47D	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human T47D cells after 3 days by SRB assay Cytotoxicity against human T47D cells after 3 days by SRB assay	[PMID: 23142674]
T47D	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
KB VCR R	IC₅₀	0.009 3 Compound: 1 (Camptothecin)	In vitro cytotoxicity against KB/VCR (Vincristine-resistant cancer cell line) In vitro cytotoxicity against KB/VCR (Vincristine-resistant cancer cell line)	[PMID: 14552770]
KB VCR R	IC₅₀	0.03 6 Compound: 1	Cytotoxicity in KB VCR R cancer cell line Cytotoxicity in KB VCR R cancer cell line	10.1016/S0960-894X(01)80158-X
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
KB-V1	IC₅₀	0.025 3 Compound: CPT	Cytotoxicity against human multidrug resistant MDR1 overexpressing human KBV1 cells after 4 days by MTT assay Cytotoxicity against human multidrug resistant MDR1 overexpressing human KBV1 cells after 4 days by MTT assay	[PMID: 18676151]
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human T47D cells by MTT assay Cytotoxicity against human T47D cells by MTT assay	[PMID: 23608763]
KB-V1	IC₅₀	0.025 3 Compound: CPT	Cytotoxicity against human KBV1 cells by MTT method Cytotoxicity against human KBV1 cells by MTT method	[PMID: 18771930]
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
T47D	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by CCK8 assay Cytotoxicity against human T47D cells after 2 days by CCK8 assay	[PMID: 26361737]
KG-1	IC₅₀	1.6 3 Compound: Camptothecin	Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 33161122]
KG-1	IC₅₀	2.31 3 Compound: Camptothecin	Antitumor activity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
T47D	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
L02	IC₅₀	0.14 3 Compound: CPT	Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay	[PMID: 35612499]
T47D	IC₅₀	0.09 3 Compound: CPT	Antiproliferative activity against human T47D cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human T47D cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
L02	IC₅₀	0.59 3 Compound: CPT	Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
T47D	IC₅₀	0.25 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human T47D cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
L02	IC₅₀	2.15 3 Compound: CPT	Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
T47D	IC₅₀	0.28 3 Compound: CPT	Cytotoxicity against human T47D cells after 2 days Cytotoxicity against human T47D cells after 2 days	[PMID: 24904965]
L02	IC₅₀	> 150 3 Compound: CPT	Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
T47D	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by CCK-8 assay Cytotoxicity against human T47D cells after 2 days by CCK-8 assay	[PMID: 24013413]
T47D	IC₅₀	0.31 3 Compound: Camptothecin	Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
T47D	IC₅₀	0.49 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
T47D	IC₅₀	0.59 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
L1210	ED₅₀	2.8 x 10^-6 2 Compound: 1, Camptothecin	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 423214]
T47D	IC₅₀	0.75 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 4 days by CCK-8 assay Cytotoxicity against human T47D cells after 4 days by CCK-8 assay	[PMID: 25062006]
T47D	IC₅₀	1.53 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
L1210	IC₅₀	0.014 3 Compound: 1	Concentration that inhibits the proliferation of L1210 cells by 50% Concentration that inhibits the proliferation of L1210 cells by 50%	[PMID: 2537428]
L1210	IC₅₀	0.015 3 Compound: Camptothecin	Cytotoxicity was measured on cultured murine lymphoblastic leukemia cells (L1210) Cytotoxicity was measured on cultured murine lymphoblastic leukemia cells (L1210)	[PMID: 8246238]
T47D	IC₅₀	1.62 3 Compound: CPT	Cytotoxicity against human T47D cells measured after 2 days by MTT assay Cytotoxicity against human T47D cells measured after 2 days by MTT assay	[PMID: 26334499]
L1210	IC₅₀	0.03 3 Compound: 1, CPT, NSC-100880	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 23578545]
T47D	IC₅₀	1.84 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay	[PMID: 26945111]
T47D	IC₅₀	1.84 3 Compound: camptothecin	Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay	[PMID: 25936262]
L1210	IC₅₀	0.03 3 Compound: Camptothecin	Inhibitory concentration required against L1210 leukemia cells Inhibitory concentration required against L1210 leukemia cells	[PMID: 12182872]
T47D	GI₅₀	1.9 3 Compound: CPT	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
L1210	IC₅₀	0.06 3 Compound: CPT	In vitro cytotoxic activity of compound against mouse leukemia L1210 cell line In vitro cytotoxic activity of compound against mouse leukemia L1210 cell line	[PMID: 15081041]
L1210	IC₅₀	0.18 3 Compound: 13 ((S)-CPT, Camptothecin)	In vitro cytotoxicity against L1210 mouse leukemia tumor cell line. In vitro cytotoxicity against L1210 mouse leukemia tumor cell line.	10.1016/0960-894X(96)00132-1
T47D	IC₅₀	11.17 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 3 days by CCK8 assay Cytotoxicity against human T47D cells after 3 days by CCK8 assay	[PMID: 26927425]
T47D	IC₅₀	13.7 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 27643560]
L1210	IC₅₀	0.18 3 Compound: CPT ((S)-Camptothecin)	Cytotoxicity against L1210 tumor cell lines in mice Cytotoxicity against L1210 tumor cell lines in mice	10.1016/0960-894X(96)00131-X
T47D	GI₅₀	2 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 48 hrs by SRB assay Antiproliferative activity against human T47D cells after 48 hrs by SRB assay	[PMID: 23831507]
L1210	IC₅₀	0.33 3 Compound: CPT	Inhibitory concentration against L1210 leukemia cell proliferation Inhibitory concentration against L1210 leukemia cell proliferation	[PMID: 12873503]
T47D	GI₅₀	2 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
L1210	IC₅₀	126 1 Compound: CPT	Compound was evaluated for cytotoxic activity on L1210 murine leukemia cells Compound was evaluated for cytotoxic activity on L1210 murine leukemia cells	10.1016/S0960-894X(97)00398-3
T47D	IC₅₀	2.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28384547]
L1210	IC₅₀	14 1 Compound: 1; CPT	Cytotoxicity against mouse L1210 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Cytotoxicity against mouse L1210 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 38421819]
L1210	IC₅₀	23 1 Compound: 1 (Camptothecin)	Inhibitory activity in mice bearing L1210 leukemia Inhibitory activity in mice bearing L1210 leukemia	[PMID: 1846923]
T47D	IC₅₀	2.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28068603]
L1210	IC₅₀	510 1 Compound: CPT	Cytotoxicity against mouse L1210 cells overexpressing folate receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against mouse L1210 cells overexpressing folate receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
T47D	IC₅₀	2.31 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28633898]
T47D	IC₅₀	207 1 Compound: 1	Cytotoxicity was determined in vitro in T47D cells(breast) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in T47D cells(breast) of human tumor cell lines by using MTT assay	[PMID: 7853331]
T47D	IC₅₀	3.67 3 Compound: Camptothecin	Cytotoxicity against human T47D cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human T47D cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
T47D	IC₅₀	4.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 26988802]
T47D	IC₅₀	9.17 3 Compound: CPT	Cytotoxicity against human T47D cells after 72 hrs by MTT assay Cytotoxicity against human T47D cells after 72 hrs by MTT assay	[PMID: 22819942]
TERT-RPE1	IC₅₀	> 40 3 Compound: Camp	Cytotoxicity against human RPE1 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human RPE1 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
TERT-RPE1	IC₅₀	27.2 3 Compound: Camp	Induction of apoptosis in human RPE1 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human RPE1 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
THP-1	IC₅₀	0.071 3 Compound: Camptothecin	Cytotoxicity against human THP1 cells after 2 days by MTT assay Cytotoxicity against human THP1 cells after 2 days by MTT assay	[PMID: 22325897]
THP-1	EC₅₀	0.16 3 Compound: camptothecin	Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method	[PMID: 20192247]
THP-1	IC₅₀	0.6 3 Compound: 1, CPT	Cytotoxicity against human THP1 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human THP1 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
THP-1	IC₅₀	1.89 3 Compound: Camptothecin	Antitumor activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
L2987	IC₅₀	0.4 3 Compound: 1 (CPT)	Compound was evaluated for antigen specific activity in vitro L2987 cell line Compound was evaluated for antigen specific activity in vitro L2987 cell line	[PMID: 11755358]
U-251	GI₅₀	0.01 3 Compound: Camptothecin	Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
U2OS	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human U2OS cells incubated for 72 hrs by MTT assay Cytotoxicity against human U2OS cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
L929	IC₅₀	1.132 3 Compound: CPT	Cytotoxicity against mouse L929 cells measured after 72 hrs Cytotoxicity against mouse L929 cells measured after 72 hrs	[PMID: 38716896]
LN-229	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human LN229 cells after 48 hrs by CCK8 assay Cytotoxicity against human LN229 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
U-373MG ATCC	IC₅₀	0.015 3 Compound: Camptothecin	Growth inhibition of human U373 cells after 72 hrs by MTT assay Growth inhibition of human U373 cells after 72 hrs by MTT assay	[PMID: 24180210]
LNCaP	ED₅₀	2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human LNCAP cells by sulforhodamine B assay Cytotoxicity against human LNCAP cells by sulforhodamine B assay	[PMID: 17350834]
U-373MG ATCC	GI₅₀	0.033 3 Compound: 1	Cytotoxicity against human U373 cells after 72 hrs by MTT assay Cytotoxicity against human U373 cells after 72 hrs by MTT assay	[PMID: 21388138]
LNCaP	ED₅₀	28 1 Compound: camptothecin	Cytotoxicity against human LNCAP cells Cytotoxicity against human LNCAP cells	[PMID: 15043407]
U-87MG ATCC	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human U87 cells measured after 72 hrs by MTT assay Antiproliferative activity against human U87 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
LNCaP	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against hormone-dependent human LNCAP cells after 2 days by sulforhodamine B assay Cytotoxicity against hormone-dependent human LNCAP cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
U-87MG ATCC	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human U87 cells after 72 hrs by MTT assay Cytotoxicity against human U87 cells after 72 hrs by MTT assay	[PMID: 21186067]
U-937	IC₅₀	0.015 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay	[PMID: 17158054]
LNCaP	IC₅₀	86.1 1 Compound: Camptothecin	Cytotoxicity against human LNCAP cells by MTT assay Cytotoxicity against human LNCAP cells by MTT assay	[PMID: 11858760]
U-937	IC₅₀	0.032 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay	[PMID: 17158054]
U-937	IC₅₀	0.3 3 Compound: 1, CPT	Cytotoxicity against human U937 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human U937 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
LOX IMVI	IC₅₀	48 1 Compound: 1	Cytotoxicity was determined in vitro in LOX cells (melanoma) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in LOX cells (melanoma) of human tumor cell lines by using MTT assay	[PMID: 7853331]
U-937	IC₅₀	0.68 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay	[PMID: 17158054]
LX-1	IC₅₀	0.12 3 Compound: camptothecin	Cytotoxicity against human LX1 cells after 72 hrs by MTS method Cytotoxicity against human LX1 cells after 72 hrs by MTS method	[PMID: 11858737]
U-937	IC₅₀	1.81 3 Compound: Camptothecin	Antitumor activity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
U-937	IC₅₀	1.98 3 Compound: Camptothecin	Cytotoxicity against human U937 cells after 2 days by MTT assay Cytotoxicity against human U937 cells after 2 days by MTT assay	[PMID: 22325897]
UACC-62	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay	[PMID: 28418653]
LoVo	GI₅₀	0.008 3 Compound: 1	Cytotoxicity against human LoVo cells after 72 hrs by MTT assay Cytotoxicity against human LoVo cells after 72 hrs by MTT assay	[PMID: 21388138]
LoVo	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human LoVo cells after 48 hrs by CCK8 assay Cytotoxicity against human LoVo cells after 48 hrs by CCK8 assay	[PMID: 30702286]
UACC-62	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human UACC62 cells after 48 hrs by SRB assay Growth inhibition of human UACC62 cells after 48 hrs by SRB assay	[PMID: 24800942]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay	[PMID: 21823606]
LoVo	IC₅₀	1.54 3 Compound: 1; CPT	Antiproliferative activity against human LoVo cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
LoVo	IC₅₀	3.1 3 Compound: CPT	Cytotoxicity against human LoVo cells after 3 days by MTT assay Cytotoxicity against human LoVo cells after 3 days by MTT assay	[PMID: 20942490]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells by SRB assay Cytotoxicity against human UACC62 cells by SRB assay	[PMID: 24502276]
Lu1	ED₅₀	29 1 Compound: camptothecin	Cytotoxicity against human Lu1 cells Cytotoxicity against human Lu1 cells	[PMID: 15043407]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells by SRB assay Antiproliferative activity against human UACC62 cells by SRB assay	[PMID: 21710981]
UACC-62	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
Lu1	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against human Lu1 cells after 2 days by sulforhodamine B assay Cytotoxicity against human Lu1 cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
Lu1	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human Lu1 cells by MTT assay Cytotoxicity against human Lu1 cells by MTT assay	[PMID: 11858760]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells after 48 hrs Antiproliferative activity against human UACC62 cells after 48 hrs	[PMID: 27070999]
M059J	IC₅₀	5.5 3 Compound: CPT	Cytotoxicity against human M059J cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human M059J cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
Vero	IC₅₀	0.02 6 Compound: camptothecin	Cytotoxicity against african green monkey Vero cells after 7 days by XTT assay Cytotoxicity against african green monkey Vero cells after 7 days by XTT assay	[PMID: 8021652]
Vero	IC₅₀	58 6 Compound: Camptothecin	Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells by MTT assay Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells by MTT assay	10.1007/s00044-010-9381-7
MCF-10A	IC₅₀	0.27 3 Compound: CPT	Cytotoxicity against human MCF10A cells after 2 days Cytotoxicity against human MCF10A cells after 2 days	[PMID: 24904965]
WI-38	IC₅₀	0.03 6 Compound: camptothecin	Cytotoxicity against human WI38 cells assessed as cell viability by WST-1 assay Cytotoxicity against human WI38 cells assessed as cell viability by WST-1 assay	[PMID: 24593048]
WI-38	IC₅₀	0.03 3 Compound: Camptothecin	Cytotoxicity against human WI38 cells after 48 hrs by WST-1 assay Cytotoxicity against human WI38 cells after 48 hrs by WST-1 assay	[PMID: 28557449]
MCF-10A	IC₅₀	0.97 3 Compound: Camptothecin	Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay	[PMID: 26361737]
MCF-10A	IC₅₀	2.19 3 Compound: 1; CPT	Antiproliferative activity against human MCF-10A cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF-10A cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
WI-38	IC₅₀	0.23 3 Compound: Campthotecin	Cytotoxicity against human WI38 cells by MTT assay Cytotoxicity against human WI38 cells by MTT assay	[PMID: 26063305]
MCF-10A	IC₅₀	2.58 3 Compound: CPT	Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human MCF-10A cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
WI-38	IC₅₀	0.4 6 Compound: Camptothecin	Cytotoxicity against human WI38 cells by MTT assay Cytotoxicity against human WI38 cells by MTT assay	[PMID: 23816880]
WI-38	IC₅₀	786 1 Compound: CPT	Cytotoxicity against human WI38 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human WI38 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
MCF-10A	IC₅₀	3.02 3 Compound: CPT	Cytotoxicity against HER-negative human MCF-10A cells incubated for 48 hrs by CCK-8 assay Cytotoxicity against HER-negative human MCF-10A cells incubated for 48 hrs by CCK-8 assay	[PMID: 38104378]
MCF-12A	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MCF12A cells after 3 days by SRB assay Cytotoxicity against human MCF12A cells after 3 days by SRB assay	[PMID: 23142674]
WI-38	IC₅₀	8.37 3 Compound: CPT	Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay	[PMID: 30685528]
MCF10	IC₅₀	24.77 3 Compound: Camptothecin	Cytotoxicity against human MCF10 cells assessed as reduction in cell viability after 3 hrs by MTT assay Cytotoxicity against human MCF10 cells assessed as reduction in cell viability after 3 hrs by MTT assay	[PMID: 33962153]
WiDr	IC₅₀	0.07 6 Compound: camptothecin	Cytotoxicity against human WiDr cells by MTT assay Cytotoxicity against human WiDr cells by MTT assay	[PMID: 18774864]
WiDr	ED₅₀	0.07 6 Compound: Camptothecin	Cytotoxicity against human WiDr cells by MTT assay Cytotoxicity against human WiDr cells by MTT assay	[PMID: 18220355]
WiDr	GI₅₀	1.7 3 Compound: CPT	Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
WiDr	GI₅₀	1.8 3 Compound: Camptothecin	Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay	[PMID: 23831507]
WIL2-NS	CC₅₀	0.005 3 Compound: Camptothecin	Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay	[PMID: 22884523]
WIL2-NS	CC₅₀	0.005 3 Compound: Camptothecin	Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay	[PMID: 22047799]
WIL2-NS	IC₅₀	0.005 3 Compound: CPT	Antiproliferative activity against human WIL-2NS cells by MTT assay Antiproliferative activity against human WIL-2NS cells by MTT assay	[PMID: 17254669]
ZR-75-1	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay	[PMID: 23142674]
ZR-75-30	IC₅₀	0.24 3 Compound: CPT	Antiproliferative activity against human ZR-7530 cells after 72 hrs by MTT assay Antiproliferative activity against human ZR-7530 cells after 72 hrs by MTT assay	[PMID: 28351590]
MCF7	CC₅₀	0.02 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22047799]
MCF7	CC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22884523]
MCF7	EC₅₀	0.072 3 Compound: camptothecin	Cytotoxicity against human MCF7 after 3 days by SRB assay Cytotoxicity against human MCF7 after 3 days by SRB assay	[PMID: 15730238]
MCF7	ED₅₀	3.2 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human MCF7 cells by sulforhodamine B assay Cytotoxicity against human MCF7 cells by sulforhodamine B assay	[PMID: 17350834]
MCF7	ED₅₀	> 10 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 2 days by sulforhodamine B assay	[PMID: 19026551]
MCF7	GI₅₀	0.002 3 Compound: Camptothecin	Growth inhibition of human MCF7 cells after 48 hrs by MTT assay Growth inhibition of human MCF7 cells after 48 hrs by MTT assay	[PMID: 23357037]
MCF7	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 20630766]
MCF7	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 21710981]
MCF7	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 24800942]
MCF7	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human MCF7 cells after 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs	[PMID: 27070999]
MCF7	GI₅₀	0.01 3 Compound: 1, CPT	Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	GI₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21115210]
MCF7	GI₅₀	0.01 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23831811]
MCF7	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of MCF7 cells after 4 days Growth inhibition of MCF7 cells after 4 days	[PMID: 17418582]
MCF7	GI₅₀	0.01 3 Compound: camptothecin	Growth inhibition of adriamycin-resistant MCF7 cells after 4 days Growth inhibition of adriamycin-resistant MCF7 cells after 4 days	[PMID: 17418582]
MCF7	GI₅₀	0.012 3 Compound: CPT	Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
MCF7	GI₅₀	0.013 3 Compound: 1	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 21823606]
MCF7	GI₅₀	0.013 3 Compound: 1	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 24502276]
MCF7	GI₅₀	0.013 3 Compound: 1	Antiproliferative activity against human MCF7 cells assessed as growth inhibition Antiproliferative activity against human MCF7 cells assessed as growth inhibition	[PMID: 28657311]
MCF7	GI₅₀	0.013 3 Compound: 18	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 28418653]
MCF7	GI₅₀	0.013 3 Compound: 2	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
MCF7	GI₅₀	0.06 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
MCF7	GI₅₀	0.28 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
MCF7	GI₅₀	0.35 3 Compound: CPT	Cytotoxicity against human MCF-7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF-7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
MCF7	GI₅₀	0.57 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay	[PMID: 20591678]
MCF7	GI₅₀	1.98 14 Compound: 1; CPT	Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 38421819]
MCF7	GI₅₀	3.21 3 Compound: CPT	Cytotoxicity against human MCF-7/TDP1 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF-7/TDP1 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 34008967]
MCF7	GI₅₀	6 3 Compound: 1	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21388138]
MCF7	IC₅₀	0.0005 3 Compound: 3	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 25084144]
MCF7	IC₅₀	0.0006 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 25247770]
MCF7	IC₅₀	0.003 3 Compound: 3	Cytotoxicity against human MCF7 cells in presence of 10 mM DTT after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells in presence of 10 mM DTT after 48 hrs by SRB assay	[PMID: 25084144]
MCF7	IC₅₀	0.021 3 Compound: CPT	In-vitro antitumor activity against human MCF7 cells incubated for 72 hrs by CCK8 assay In-vitro antitumor activity against human MCF7 cells incubated for 72 hrs by CCK8 assay	[PMID: 35550978]
MCF7	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 20392545]
MCF7	IC₅₀	0.02 6 Compound: 1	Cytotoxicity in MCF-7 cancer cell line Cytotoxicity in MCF-7 cancer cell line	10.1016/S0960-894X(01)80158-X
MCF7	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 28274626]
MCF7	IC₅₀	0.03 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 31546197]
MCF7	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 17254669]
MCF7	IC₅₀	0.04 3 Compound: CPT	Cytotoxicity against against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
MCF7	IC₅₀	0.056 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 21978950]
MCF7	IC₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay	[PMID: 19939682]
MCF7	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 21513293]
MCF7	IC₅₀	0.073 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay	[PMID: 28409637]
MCF7	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells incubated for 3 days by SRB assay Cytotoxicity against human MCF7 cells incubated for 3 days by SRB assay	[PMID: 22863526]
MCF7	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay	[PMID: 25481396]
MCF7	IC₅₀	0.084 3 Compound: CPT	Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay	[PMID: 32292547]
MCF7	IC₅₀	0.2 3 Compound: 1, CPT	Cytotoxicity against human MCF7 cells after 4 days by MTT assay Cytotoxicity against human MCF7 cells after 4 days by MTT assay	[PMID: 18554906]
MCF7	IC₅₀	0.32 3 Compound: CPT	In vitro cytotoxic activity of compound against human MCF-7 cell line In vitro cytotoxic activity of compound against human MCF-7 cell line	[PMID: 15081041]
MCF7	IC₅₀	0.324 3 Compound: CPT	Cytotoxicity against human MCF7 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
MCF7	IC₅₀	0.34 3 Compound: Camp	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
MCF7	IC₅₀	0.35 3 Compound: CPT	Cytotoxicity against human MCF7 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
MCF7	IC₅₀	0.42 3 Compound: CPT	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30125725]
MCF7	IC₅₀	0.56 3 Compound: 1; CPT	Antiproliferative activity against human MCF7 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
MCF7	IC₅₀	0.65 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21186067]
MCF7	IC₅₀	0.68 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30600208]
MCF7	IC₅₀	0.68 3 Compound: CPT; 1	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30509782]
MCF7	IC₅₀	1.1 3 Compound: 1, CPT	Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay Cytotoxicity against estrogen receptor-positive human MCF7 cells expressing wild type p53 after 48 hrs by SRB assay	[PMID: 19715319]
MCF7	IC₅₀	1.22 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by SRB staining-based fluorescence cytometry Cytotoxicity against human MCF7 cells by SRB staining-based fluorescence cytometry	[PMID: 19653666]
MCF7	IC₅₀	1.6 1 Compound: Camptothecin	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 22376176]
MCF7	IC₅₀	1.6 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells by SRB assay Cytotoxicity against human MCF7 cells by SRB assay	[PMID: 21410162]
MCF7	IC₅₀	1.67 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
MCF7	IC₅₀	1.8 3 Compound: camptothecin	Cytotoxicity against human tamoxifen-resistant MCF7 cells by WST-1 assay Cytotoxicity against human tamoxifen-resistant MCF7 cells by WST-1 assay	[PMID: 22197145]
MCF7	IC₅₀	10 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 19655762]
MCF7	IC₅₀	10 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 18841903]
MCF7	IC₅₀	11.12 3 Compound: 4	Anticancer activity against human MCF7 cells Anticancer activity against human MCF7 cells	[PMID: 21599000]
MCF7	IC₅₀	13.62 3 Compound: Camptothecin	Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
MCF7	IC₅₀	14.2 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 4 days by MTT assay Cytotoxicity against human MCF7 cells after 4 days by MTT assay	[PMID: 20619511]
MCF7	IC₅₀	160 1 Compound: Camptothecin	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
MCF7	IC₅₀	18.6 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 36996717]
MCF7	IC₅₀	2.43 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 21115246]
MCF7	IC₅₀	2.5 3 Compound: CPT	Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis	[PMID: 30897325]
MCF7	IC₅₀	2.5 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hr by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hr by MTT assay	[PMID: 32682183]
MCF7	IC₅₀	2.6 3 Compound: camptothecin	Cytotoxicity against human MCF7 cells by WST-1 assay Cytotoxicity against human MCF7 cells by WST-1 assay	[PMID: 22197145]
MCF7	IC₅₀	2.8 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CytoX cell viability assay	[PMID: 32526552]
MCF7	IC₅₀	26 1 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24900725]
MCF7	IC₅₀	28.66 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28462840]
MCF7	IC₅₀	3 1 Compound: camptothecin	Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay	[PMID: 19655762]
MCF7	IC₅₀	3.1 1 Compound: 1; CPT	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38421819]
MCF7	IC₅₀	3.1 1 Compound: CPT	Antiproliferative activity measured against MCF-7-mdr cells. Antiproliferative activity measured against MCF-7-mdr cells.	[PMID: 9876111]
MCF7	IC₅₀	3.3 1 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells by SRB assay Antiproliferative activity against human MCF7 cells by SRB assay	[PMID: 24200393]
MCF7	IC₅₀	3.91 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 2 days Cytotoxicity against human MCF7 cells after 2 days	[PMID: 22318164]
MCF7	IC₅₀	4.54 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
MCF7	IC₅₀	6 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 24 hrs by XTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 24 hrs by XTT assay	[PMID: 26649907]
MCF7	IC₅₀	6.39 3 Compound: CPT	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
MCF7	IC₅₀	6.85 3 Compound: CPT	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
MCF7	IC₅₀	65.1 1 Compound: CPT	Cytotoxicity against human MCF7 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
MCF7	IC₅₀	7.42 3 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 3 days Cytotoxicity against human MCF7 cells after 3 days	[PMID: 19954977]
MCF7	IC₅₀	71.3 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28063351]
MCF7	IC₅₀	87.5 1 Compound: 1	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 28927790]
MCF7	IC₅₀	87.5 1 Compound: 1; CPT	Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine containing medium assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against multidrug resistant human MCF7 cells cultured in vinblastine free medium assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
MCF7	IC₅₀	< 0.0018 3 Compound: Camptothecin	Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against vinblastine-sensitive human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28006904]
MCF7	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 23142674]
MCF7	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human MCF7 cells after 72 hrs by MTT assay Growth inhibition of human MCF7 cells after 72 hrs by MTT assay	[PMID: 24180210]
MCF7	IC₅₀	< 0.01 3 Compound: Camptothecin	Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 6 days by SRB assay Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 6 days by SRB assay	[PMID: 38107170]
MCF7	IC₅₀	< 0.024 6 Compound: Camptothecin	Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay	[PMID: 24940955]
MCF7	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 22409771]
MCF7	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MCF7	IC₅₀	<= 0.1 3 Compound: CPT	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
MDA-MB-157	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human MDA-MB-157 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-157 cells after 3 days by SRB assay	[PMID: 23142674]
MDA-MB-231	GI₅₀	0.4 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
MDA-MB-231	GI₅₀	1.3 3 Compound: Camptothecin	Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay	[PMID: 20438092]
MDA-MB-231	IC₅₀	0.108 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
MDA-MB-231	IC₅₀	0.17 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 34171512]
MDA-MB-231	IC₅₀	0.241 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay	[PMID: 34052678]
MDA-MB-231	IC₅₀	0.291 3 Compound: camptothecin	Growth inhibition of human MDA-MB-231 cells by neutral red assay Growth inhibition of human MDA-MB-231 cells by neutral red assay	[PMID: 17204425]
MDA-MB-231	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system	[PMID: 20392646]
MDA-MB-231	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human MDA231 cells after 48 hrs by CCK8 assay Cytotoxicity against human MDA231 cells after 48 hrs by CCK8 assay	[PMID: 30702286]
MDA-MB-231	IC₅₀	0.33 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 after 48 hrs by SRB assay Cytotoxicity against human MDA-MB-231 after 48 hrs by SRB assay	[PMID: 21044847]
MDA-MB-231	IC₅₀	0.342 3 Compound: CPT, Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 24 hrs by MTT assay	[PMID: 24980118]
MDA-MB-231	IC₅₀	0.42 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
MDA-MB-231	IC₅₀	0.49 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
MDA-MB-231	IC₅₀	0.53 3 Compound: CPT	Cytotoxicity against HER-negative human MDA-MB-231 cells incubated for 48 hrs by CCK-8 assay Cytotoxicity against HER-negative human MDA-MB-231 cells incubated for 48 hrs by CCK-8 assay	[PMID: 38104378]
MDA-MB-231	IC₅₀	0.62 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
MDA-MB-231	IC₅₀	0.68 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells by MTT assay Cytotoxicity against human MDA-MB-231 cells by MTT assay	[PMID: 19836231]
MDA-MB-231	IC₅₀	0.92 3 Compound: camptothecin	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 20093033]
MDA-MB-231	IC₅₀	0.97 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 2 days Cytotoxicity against human MDA-MB-231 cells after 2 days	[PMID: 21419530]
MDA-MB-231	IC₅₀	1.06 3 Compound: CPT	Cytotoxicity against HER-negative human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-negative human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
MDA-MB-231	IC₅₀	1.1 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 3 days Cytotoxicity against human MDA-MB-231 cells after 3 days	[PMID: 19954977]
MDA-MB-231	IC₅₀	16.44 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 30109008]
MDA-MB-231	IC₅₀	162 1 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 24900725]
MDA-MB-231	IC₅₀	2.11 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
MDA-MB-231	IC₅₀	2.7 3 Compound: camptothecin	Cytotoxicity against human MDA-MB-231 cells by WST-1 assay Cytotoxicity against human MDA-MB-231 cells by WST-1 assay	[PMID: 22197145]
MDA-MB-231	IC₅₀	23.98 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
MDA-MB-231	IC₅₀	264 1 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Ctrl assessed as cell viability by MTT assay Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Ctrl assessed as cell viability by MTT assay	[PMID: 34844412]
MDA-MB-231	IC₅₀	28.4 1 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 4 days by [3H]-thymidine incorporation assay	[PMID: 32952994]
MDA-MB-231	IC₅₀	307 1 Compound: 1	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay	[PMID: 28927790]
MDA-MB-231	IC₅₀	307 1 Compound: 1; CPT	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay	[PMID: 28285912]
MDA-MB-231	IC₅₀	4.16 3 Compound: camptothecin	Cytotoxicity against human MDA-MB-231 cells Cytotoxicity against human MDA-MB-231 cells	[PMID: 18178085]
MDA-MB-231	IC₅₀	4.2 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay	[PMID: 20619511]
MDA-MB-231	IC₅₀	5.77 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay	[PMID: 26602827]
MDA-MB-231	IC₅₀	540 1 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
MDA-MB-231	IC₅₀	8.83 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
MDA-MB-231	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 23142674]
MDA-MB-231	IC₅₀	< 0.01 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition	[PMID: 38107170]
MDA-MB-231	IC₅₀	> 100 3 Compound: CPT	Cytotoxicity against human MDA-MB-231 cells Cytotoxicity against human MDA-MB-231 cells	[PMID: 36924947]
MDA-MB-231	IC₅₀	> 100 3 Compound: CPT	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
MDA-MB-231	IC₅₀	> 6.4 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Top1 assessed as cell viability by MTT assay Antiproliferative activity against human MDA-MB-231 cells transfected with siRNA-Top1 assessed as cell viability by MTT assay	[PMID: 34844412]
MDA-MB-361	IC₅₀	0.17 3 Compound: CPT	Cytotoxicity against human MDA-MB-361 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-361 cells after 3 days by SRB assay	[PMID: 23142674]
MDA-MB-361	IC₅₀	0.17 3 Compound: Camptothecin	Antitumor activity against human MDA-MB-361 cells assessed as tumor growth inhibition Antitumor activity against human MDA-MB-361 cells assessed as tumor growth inhibition	[PMID: 38107170]
MDA-MB-435	GI₅₀	0.033 3 Compound: 1, CPT	Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
MDA-MB-435	GI₅₀	0.04 3 Compound: 1	Antiproliferative activity against human MDA-MB-435 cell line Antiproliferative activity against human MDA-MB-435 cell line	[PMID: 16442283]
MDA-MB-435	GI₅₀	0.04 3 Compound: 1	Antiproliferative activity against human MDA-MB-435 cells Antiproliferative activity against human MDA-MB-435 cells	[PMID: 18630891]
MDA-MB-435	GI₅₀	0.04 3 Compound: 1	Cytotoxicity against human MDA-MB-435 cells Cytotoxicity against human MDA-MB-435 cells	[PMID: 19783447]
MDA-MB-435	GI₅₀	0.04 3 Compound: 1, CPT	Antiproliferative activity against human MDA-MB-435 cells Antiproliferative activity against human MDA-MB-435 cells	[PMID: 20155916]
MDA-MB-435	GI₅₀	0.04 3 Compound: 1, Camptothecin	Cytotoxicity against human MDA-MB-435 cells Cytotoxicity against human MDA-MB-435 cells	[PMID: 17676830]
MDA-MB-435	GI₅₀	0.04 3 Compound: 2	Growth inhibitory activity against human breast MDA-MB-435 cell line Growth inhibitory activity against human breast MDA-MB-435 cell line	[PMID: 15509164]
MDA-MB-435	GI₅₀	0.04 3 Compound: 2	Antiproliferative activity against human MDA-MB-435 cell line Antiproliferative activity against human MDA-MB-435 cell line	[PMID: 16913702]
MDA-MB-435	GI₅₀	0.04 3 Compound: 2	Cytotoxicity against human MDA-MB-435 cells Cytotoxicity against human MDA-MB-435 cells	[PMID: 17696418]
MDA-MB-435	GI₅₀	0.04 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human breast MDA-MB-435 cell line Antiproliferative activity was determined for 50% growth inhibition against human breast MDA-MB-435 cell line	[PMID: 11020283]
MDA-MB-435	GI₅₀	0.04 3 Compound: Camptothecin	Concentration required to inhibit the growth of human Breast MDA-MB-435 cells Concentration required to inhibit the growth of human Breast MDA-MB-435 cells	[PMID: 16033260]
MDA-MB-435	IC₅₀	0.0436 3 Compound: CPT	Antiproliferative activity against human MDA-MB-435 cells after 3 days by MTT assay Antiproliferative activity against human MDA-MB-435 cells after 3 days by MTT assay	[PMID: 23084702]
MDA-MB-435	IC₅₀	0.31 3 Compound: 1; CPT	Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition rate incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition rate incubated for 72 hrs by MTT assay	[PMID: 34844412]
MDA-MB-435	IC₅₀	0.71 3 Compound: CPT	Cytotoxicity against human MDA-MB-435 cells after 3 days by MTT assay Cytotoxicity against human MDA-MB-435 cells after 3 days by MTT assay	[PMID: 20942490]
MDA-MB-435	IC₅₀	1 3 Compound: CPT	Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay	[PMID: 26226379]
MDA-MB-435	IC₅₀	15 1 Compound: camptothecin	Inhibition against MDA-MB-435 human breast cancer cells in the absence of HSA Inhibition against MDA-MB-435 human breast cancer cells in the absence of HSA	[PMID: 11052802]
MDA-MB-435	IC₅₀	2.7 3 Compound: CPT	Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
MDA-MB-435	IC₅₀	375 1 Compound: camptothecin	Inhibition against MDA-MB-435 human breast cancer cells in the presence of 11 mg/mL HSA Inhibition against MDA-MB-435 human breast cancer cells in the presence of 11 mg/mL HSA	[PMID: 11052802]
MDA-MB-435	IC₅₀	< 0.001 3 Compound: 1, CPT	Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay	[PMID: 24069881]
MDA-MB-436	IC₅₀	31.86 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-436 cells measured after 72 hrs by Ez-cytox assay Antiproliferative activity against human MDA-MB-436 cells measured after 72 hrs by Ez-cytox assay	[PMID: 31398033]
MDA-MB-453	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human MDA-MB-453 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-453 cells after 3 days by SRB assay	[PMID: 23142674]
MDA-MB-453	IC₅₀	< 0.01 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-453 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-453 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 38107170]
MDA-MB-468	IC₅₀	1.71 3 Compound: Camptothecin	Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
MDA-MB-468	IC₅₀	14.76 3 Compound: Camptothecin	Antiproliferative activity against human MDA-MB-468 cells after 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-468 cells after 72 hrs by SRB assay	[PMID: 26602827]
MDA-MB-468	IC₅₀	> 100 3 Compound: CPT	Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
MEF	IC₅₀	5.87 6 Compound: Camptothecin	Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay	[PMID: 25867737]
MES-SA	IC₅₀	57 1 Compound: 1a	Cytotoxicity against human MESSA cells after 72 hrs by alamar blue assay Cytotoxicity against human MESSA cells after 72 hrs by alamar blue assay	[PMID: 21341674]
MES-SA/Dx5	IC₅₀	52 1 Compound: 1a	Cytotoxicity against human MES-SA/Dx5 cells overexpressing MDR1 after 72 hrs by alamar blue assay Cytotoxicity against human MES-SA/Dx5 cells overexpressing MDR1 after 72 hrs by alamar blue assay	[PMID: 21341674]
MFE-296	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MG-63	IC₅₀	0.046 3 Compound: CPT	Cytotoxicity against human MG-63 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MG-63 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
MGC-803	IC₅₀	17.76 3 Compound: Camptothecin	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 36996717]
MGC-803	IC₅₀	2.96 3 Compound: CPT	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 30685528]
MGC-803	IC₅₀	4.27 3 Compound: CPT	Antiproliferative activity against human MGC803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
MGC-803	IC₅₀	9.45 3 Compound: Camptothecin	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28462840]
MGC-803	IC₅₀	> 100 3 Compound: CPT	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
MGC-803	IC₅₀	> 150 3 Compound: CPT	Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
MHCC97H	IC₅₀	0.32 1 Compound: Camptothecin	Cytotoxicity against human MHCC97H cells after 48 hrs by CCK8 assay Cytotoxicity against human MHCC97H cells after 48 hrs by CCK8 assay	[PMID: 30702286]
MIA PaCa-2	IC₅₀	0.18 3 Compound: CPT	Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in presence of type 1 collagen coated surface by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in presence of type 1 collagen coated surface by MTT assay	[PMID: 28689976]
MIA PaCa-2	IC₅₀	0.19 3 Compound: Camptothecin	Antiproliferative activity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
MIA PaCa-2	IC₅₀	0.19 3 Compound: Camptothecin	Cytotoxicity against human MIAPaCa2 cells after 48 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells after 48 hrs by MTT assay	[PMID: 24041234]
MIA PaCa-2	IC₅₀	0.4 3 Compound: Camptothecin	Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay	[PMID: 21775156]
MIA PaCa-2	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
MKN-45	IC₅₀	17 1 Compound: CPT	In Vitro cytotoxicity against human stomach cancer cell line (MKN45) In Vitro cytotoxicity against human stomach cancer cell line (MKN45)	[PMID: 11334569]
MOLT-4	IC₅₀	0.04 1 Compound: CPT	Cytotoxicity against human MOLT4 cells after 72 hrs by MTT assay Cytotoxicity against human MOLT4 cells after 72 hrs by MTT assay	[PMID: 24900725]
MRC5	CC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay	[PMID: 22047799]
MRC5	CC₅₀	0.2 3 Compound: Camptothecin	Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay Cytotoxicity against human MRC5 cells after 96 hrs by MTT assay	[PMID: 22884523]
MRC5	IC₅₀	0.8 3 Compound: CPT	Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 3 days by resazurin staining based analysis Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 3 days by resazurin staining based analysis	[PMID: 34952177]
MRC5	IC₅₀	0.89 3 Compound: 4	Antiproliferative activity against human MRC5 cells Antiproliferative activity against human MRC5 cells	[PMID: 21599000]
MRC5	IC₅₀	1.7 x 10^-5 3 Compound: CPT	Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
MRC5	IC₅₀	1.7 3 Compound: I; CPT	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
MRC5	IC₅₀	9.02 3 Compound: Camptothecin	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36758308]
MRC5	IC₅₀	> 300 3 Compound: CPT	Cytostatic activity against human MRC5 cells after 24 hrs by CCK-8 assay Cytostatic activity against human MRC5 cells after 24 hrs by CCK-8 assay	[PMID: 38278140]
MSTO-211H	GI₅₀	0.0021 3 Compound: CPT	Growth inhibition of human MSTO-211H cells after 72 hrs by trypan blue assay Growth inhibition of human MSTO-211H cells after 72 hrs by trypan blue assay	[PMID: 27597409]
MT4	CC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human MT4 cells after 96 hrs by MTT assay Cytotoxicity against human MT4 cells after 96 hrs by MTT assay	[PMID: 22884523]
MT4	CC₅₀	0.01 3 Compound: Camptothecin	Compound concentration required to reduce the exponential growth of MT-4 cells by 50% Compound concentration required to reduce the exponential growth of MT-4 cells by 50%	[PMID: 9767632]
MT4	IC₅₀	0.004 3 Compound: CPT	Antiproliferative activity against human MT4 cells by MTT assay Antiproliferative activity against human MT4 cells by MTT assay	[PMID: 17254669]
MT4	IC₅₀	0.004 3 Compound: Camptothecin	Cytotoxicity against human MT4 cells after 96 hrs Cytotoxicity against human MT4 cells after 96 hrs	[PMID: 22276775]
MX1	IC₅₀	1700 1 Compound: CPT	Cytotoxicity against human MX1 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MX1 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
Macrophage	EC₅₀	18.32 3 Compound: CPT	Cytotoxicity against BALB/c mouse macrophage assessed as cell viability measured after 48 hrs infection by propidium iodide staining analysis relative to control Cytotoxicity against BALB/c mouse macrophage assessed as cell viability measured after 48 hrs infection by propidium iodide staining analysis relative to control	[PMID: 36823782]
Macrophage	IC₅₀	0.62 3 Compound: CPT	Cytotoxicity against BALB/C mouse macrophages Cytotoxicity against BALB/C mouse macrophages	[PMID: 22932312]
Mahlavu	IC₅₀	< 0.1 3 Compound: CPT	Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 22409771]
Mahlavu	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
NB-4	IC₅₀	2.01 3 Compound: Camptothecin	Antitumor activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
NCI-H128	IC₅₀	18 1 Compound: CPT	In Vitro cytotoxicity against human lung cancer cell line (H128) In Vitro cytotoxicity against human lung cancer cell line (H128)	[PMID: 11334569]
NCI-H1299	IC₅₀	0.8 3 Compound: Camptothecin	Cytotoxicity against human NCI-H1299 cells by MTT assay Cytotoxicity against human NCI-H1299 cells by MTT assay	[PMID: 28506750]
NCI-H1299	IC₅₀	3.14 3 Compound: CPT	Antiproliferative activity against human H1299 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human H1299 cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
NCI-H1299	IC₅₀	> 100 3 Compound: CPT	Antiproliferative activity against human NCI-H1299 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human NCI-H1299 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
NCI-H1975	IC₅₀	1.2 3 Compound: Camptothecin	Cytotoxicity against human NCI-H1975 cells by MTT assay Cytotoxicity against human NCI-H1975 cells by MTT assay	[PMID: 28506750]
NCI-H23	IC₅₀	0.07 3 Compound: CPT	Cytotoxicity against human NCI-H23 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human NCI-H23 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
NCI-H446	IC₅₀	> 200 3 Compound: CPT	Cytotoxicity against human NCI-H446 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H446 cells after 72 hrs by MTT assay	[PMID: 26226379]
NCI-H446	IC₅₀	> 200 3 Compound: CPT	Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
NCI-H460	EC₅₀	0.0069 3 Compound: camptothecin	Cytotoxicity against human H460 after 3 days by SRB assay Cytotoxicity against human H460 after 3 days by SRB assay	[PMID: 15730238]
NCI-H460	GI₅₀	0.002 3 Compound: CPT	Growth inhibition of human H460 cells after 72 hrs by trypan blue assay Growth inhibition of human H460 cells after 72 hrs by trypan blue assay	[PMID: 27597409]
NCI-H460	GI₅₀	0.0057 3 Compound: Camptothecin	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
NCI-H460	GI₅₀	0.03 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay	[PMID: 20591678]
NCI-H460	IC₅₀	0.002 3 Compound: Camptothecin	Cytotoxicity against human NCI-H460 cells incubated for 3 days by SRB assay Cytotoxicity against human NCI-H460 cells incubated for 3 days by SRB assay	[PMID: 22863526]
NCI-H460	IC₅₀	0.003 3 Compound: Camptothecin	Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by MTT assay	[PMID: 22758788]
NCI-H460	IC₅₀	0.0062 3 Compound: 1, CPT	Cytotoxicity against human H460 cells after 72 hrs Cytotoxicity against human H460 cells after 72 hrs	[PMID: 18419110]
NCI-H460	IC₅₀	0.03 3 Compound: 4	Anticancer activity against human NCI-H460 cells Anticancer activity against human NCI-H460 cells	[PMID: 21599000]
NCI-H460	IC₅₀	0.12 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 32711231]
NCI-H460	IC₅₀	0.18 3 Compound: 1, camptothecin, CPT	Antiproliferative activity against human H460 cells after 1 hr of drug exposure measured after 72 hrs Antiproliferative activity against human H460 cells after 1 hr of drug exposure measured after 72 hrs	[PMID: 18424133]
NCI-H460	IC₅₀	0.19 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells assessed as cell viability after 96 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as cell viability after 96 hrs by MTT assay	[PMID: 27156772]
NCI-H460	IC₅₀	0.33 3 Compound: 1, CPT	Cytotoxicity against human H460 cells after 1 hr Cytotoxicity against human H460 cells after 1 hr	[PMID: 18419110]
NCI-H460	IC₅₀	0.33 3 Compound: 1, CPT	Antiproliferative activity against human NCI-H460 cells after short term exposure for 1 hr measured after 72 hrs in drug-free medium Antiproliferative activity against human NCI-H460 cells after short term exposure for 1 hr measured after 72 hrs in drug-free medium	[PMID: 19530720]
NCI-H460	IC₅₀	0.33 3 Compound: 1a (Camptothecin)	In vitro cytotoxic activity against human non small cell lung carcinoma H460 cell line In vitro cytotoxic activity against human non small cell lung carcinoma H460 cell line	[PMID: 11052801]
NCI-H460	IC₅₀	0.79 3 Compound: Camptothecin	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36758308]
NCI-H460	IC₅₀	110 1 Compound: Camptothecin	Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 29541373]
NCI-H460	IC₅₀	13 1 Compound: 1a	Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
NCI-H460	IC₅₀	5 1 Compound: Cpt	Cytotoxicity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human NCI-H460 cells after 72 hrs by sulforhodamine B assay	[PMID: 22749423]
NCI-H460	IC₅₀	5.37 3 Compound: CPT	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
NCI-H460	IC₅₀	< 0.04 3 Compound: Camptothecin	Cytotoxicity against human H460 cells after 72 hrs by MTS assay Cytotoxicity against human H460 cells after 72 hrs by MTS assay	[PMID: 21513293]
NCI-H460	IC₅₀	> 1000 1 Compound: 1a	Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay in presence of 40 mg/ml HSA Cytotoxicity against human H460 cells after 72 hrs by alamar blue assay in presence of 40 mg/ml HSA	[PMID: 21341674]
NCI-H460	IC₅₀	> 25 3 Compound: CPT	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 20638158]
NCI-H520	IC₅₀	25.01 1 Compound: CPT	Cytotoxicity against human NCI-H520 cells assessed as inhibition of cell growth Cytotoxicity against human NCI-H520 cells assessed as inhibition of cell growth	[PMID: 37806498]
NCI-H69	IC₅₀	1 1 Compound: 1a	Cytotoxicity against human H69 cells after 72 hrs by alamar blue assay Cytotoxicity against human H69 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
NCI-H928	IC₅₀	7.8 1 Compound: 1	Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]-thymidine into cellular DNA of human lung carcinoma cells (H928) Cytotoxicity expressed as the concentration that inhibited incorporation of [3H]-thymidine into cellular DNA of human lung carcinoma cells (H928)	[PMID: 10479293]
NCI-N87	IC₅₀	0.6 3 Compound: Camptothecin	Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
NCI-N87	IC₅₀	2.07 3 Compound: CPT	Cytotoxicity against HER-positive human NCI-N87 cells incubated for 48 hrs by CCK-8 assay Cytotoxicity against HER-positive human NCI-N87 cells incubated for 48 hrs by CCK-8 assay	[PMID: 38104378]
NCI-N87	IC₅₀	2.32 3 Compound: CPT	Cytotoxicity against HER-positive human NCI-N87 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human NCI-N87 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
NCI/ADR-RES	IC₅₀	0.8 3 Compound: camptothecin	Cytotoxicity against human MCF7/ADR cells by WST-1 assay Cytotoxicity against human MCF7/ADR cells by WST-1 assay	[PMID: 22197145]
NHDF	IC₅₀	5.38 3 Compound: Camptothecin	Cytotoxicity against HDF cells Cytotoxicity against HDF cells	[PMID: 32932211]
NIH3T3	IC₅₀	0.086 3 Compound: CPT	Cytotoxicity against mouse NIH3T3 cells measured after 72 hrs Cytotoxicity against mouse NIH3T3 cells measured after 72 hrs	[PMID: 38716896]
NIH3T3	IC₅₀	12 3 Compound: Camptothecin	Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed form Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed form	[PMID: 11430001]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR-3 cell line Antiproliferative activity against human OVCAR-3 cell line	[PMID: 16442283]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR-3 cells Cytotoxicity against human OVCAR-3 cells	[PMID: 17402722]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR-3 cells Antiproliferative activity against human OVCAR-3 cells	[PMID: 18630891]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR-3 cells Cytotoxicity against human OVCAR-3 cells	[PMID: 19783447]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR-3 cells Cytotoxicity against human OVCAR-3 cells	[PMID: 20630766]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR3 cells by SRB assay Antiproliferative activity against human OVCAR3 cells by SRB assay	[PMID: 21710981]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 21823606]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Cytotoxicity against human OVCAR3 cells by SRB assay Cytotoxicity against human OVCAR3 cells by SRB assay	[PMID: 24502276]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 24800942]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR3 cells after 48 hrs Antiproliferative activity against human OVCAR3 cells after 48 hrs	[PMID: 27070999]
OVCAR-3	GI₅₀	0.22 3 Compound: 1	Antiproliferative activity against human OVCAR3 cells assessed as growth inhibition Antiproliferative activity against human OVCAR3 cells assessed as growth inhibition	[PMID: 28657311]
OVCAR-3	GI₅₀	0.22 3 Compound: 1, CPT	Antiproliferative activity against human OVCAR-3 cells Antiproliferative activity against human OVCAR-3 cells	[PMID: 20155916]
OVCAR-3	GI₅₀	0.22 3 Compound: 1, Camptothecin	Cytotoxicity against human OVCAR-3 cells Cytotoxicity against human OVCAR-3 cells	[PMID: 17676830]
OVCAR-3	GI₅₀	0.22 3 Compound: 18	Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay Cytotoxicity against human OVCAR3 cells after 48 hrs by SRB assay	[PMID: 28418653]
OVCAR-3	GI₅₀	0.22 3 Compound: 2	Growth inhibitory activity against human ovarian OVCAR-3 cell line Growth inhibitory activity against human ovarian OVCAR-3 cell line	[PMID: 15509164]
OVCAR-3	GI₅₀	0.22 3 Compound: 2	Antiproliferative activity against human OVCAR-3 cell line Antiproliferative activity against human OVCAR-3 cell line	[PMID: 16913702]
OVCAR-3	GI₅₀	0.22 3 Compound: 2	Cytotoxicity against human OVCAR-3 cells Cytotoxicity against human OVCAR-3 cells	[PMID: 17696418]
OVCAR-3	GI₅₀	0.22 3 Compound: 2	Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
OVCAR-3	GI₅₀	0.22 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human ovarian OVCAR-3 cell line Antiproliferative activity was determined for 50% growth inhibition against human ovarian OVCAR-3 cell line	[PMID: 11020283]
P388	ED₅₀	8.6 x 10^-6 2 Compound: 1, Camptothecin	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 423214]
P388	IC₅₀	0.004 1 Compound: CPT, campothecin	Cytotoxicity against human P388 cells Cytotoxicity against human P388 cells	[PMID: 18511275]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells by MTT method Cytotoxicity against mouse P388 cells by MTT method	[PMID: 18771930]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT assay Cytotoxicity against mouse P388 cells after 4 days by MTT assay	[PMID: 19299037]
P388	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT method Cytotoxicity against mouse P388 cells after 4 days by MTT method	[PMID: 19303306]
P388	IC₅₀	0.005 6 Compound: Camptothecin (CPT)	Tested for the cytostatic activity as inhibitory concentration against P-388 mouse leukemia cells Tested for the cytostatic activity as inhibitory concentration against P-388 mouse leukemia cells	10.1016/S0960-894X(97)00071-1
P388	IC₅₀	0.009 3 Compound: CPT	Cytotoxicity against mouse P388 cells after 4 days by MTT assay Cytotoxicity against mouse P388 cells after 4 days by MTT assay	[PMID: 18676151]
P388	IC₅₀	0.01 3 Compound: CPT	Concentration required to inhibit cell proliferation in P388 tumor cell line Concentration required to inhibit cell proliferation in P388 tumor cell line	[PMID: 15482929]
P388	IC₅₀	0.014 3 Compound: CPT	Cytotoxicity against mouse P388 cells after MTT assay Cytotoxicity against mouse P388 cells after MTT assay	[PMID: 18829334]
P388	IC₅₀	0.014 3 Compound: CPT	Cytotoxicity against mouse P388 cells by MTT method Cytotoxicity against mouse P388 cells by MTT method	[PMID: 19012996]
P388	IC₅₀	0.032 3 Compound: CPT	In vitro inhibitory concentration against murine P388 leukemia cell proliferation In vitro inhibitory concentration against murine P388 leukemia cell proliferation	[PMID: 10346933]
P388	IC₅₀	13 1 Compound: Camptothecin	Inhibitory activity against P388 murine leukemia cells Inhibitory activity against P388 murine leukemia cells	[PMID: 11384245]
P388	IC₅₀	13 1 Compound: Camptothecin	Growth inhibitory activity against murine P388 leukemia cells Growth inhibitory activity against murine P388 leukemia cells	[PMID: 12620081]
P388	IC₅₀	32.1 1 Compound: camptothecin	Cytotoxicity against mouse P388 cells after 72 hrs Cytotoxicity against mouse P388 cells after 72 hrs	[PMID: 17624792]
P388	IC₅₀	4.74 14 Compound: 1	In vitro antitumor activity against P388 (murine leukemia) cells. In vitro antitumor activity against P388 (murine leukemia) cells.	[PMID: 9632364]
P388	IC₅₀	4.74 14 Compound: 1a	Tested in vitro for the inhibition of P388 (mouse leukemia) cell line by MTT assay Tested in vitro for the inhibition of P388 (mouse leukemia) cell line by MTT assay	[PMID: 7932525]
P388	IC₅₀	7 1 Compound: Camptothecin	Inhibitory activity against P388 Leukemia cells Inhibitory activity against P388 Leukemia cells	[PMID: 12565975]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against mouse CPT45-resistant topoisomerase 1-deficient P388 cells after 4 days by MTT assay Cytotoxicity against mouse CPT45-resistant topoisomerase 1-deficient P388 cells after 4 days by MTT assay	[PMID: 18676151]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant mouse P388 cells by MTT method Cytotoxicity against camptothecin-resistant mouse P388 cells by MTT method	[PMID: 18771930]
P388	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant mouse P388 cells after 4 days by MTT method Cytotoxicity against camptothecin-resistant mouse P388 cells after 4 days by MTT method	[PMID: 19303306]
P388CPT45	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against camptothecin-resistant and TOP1 deficient mouse P388/CPT45 cells after MTT assay Cytotoxicity against camptothecin-resistant and TOP1 deficient mouse P388/CPT45 cells after MTT assay	[PMID: 18829334]
P388CPT45	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against mouse P388/CPT45 cells after 4 days by MTT assay Cytotoxicity against mouse P388/CPT45 cells after 4 days by MTT assay	[PMID: 19299037]
P388CPT5	IC₅₀	2.8 3 Compound: CPT	In vitro inhibitory concentration against murine P388CPT5 leukemia cell proliferation In vitro inhibitory concentration against murine P388CPT5 leukemia cell proliferation	[PMID: 10346933]
PANC-1	GI₅₀	6.29 3 Compound: 1, CPT	Cytotoxicity against human PANC1 cells incubated for 72 hrs by MTT assay Cytotoxicity against human PANC1 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
PANC-1	IC₅₀	0.09 3 Compound: CPT	Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay Cytotoxicity against human PANC1 cells after 72 hrs by XTT assay	[PMID: 30017114]
PANC-1	IC₅₀	0.18 3 Compound: CPT	Cytotoxicity against human PANC1 cells after 48 hrs by XTT assay Cytotoxicity against human PANC1 cells after 48 hrs by XTT assay	[PMID: 30017114]
PANC-1	IC₅₀	0.233 3 Compound: CPT	Cytotoxicity against human PANC-1 cells incubated for 48 hrs by MTT assay Cytotoxicity against human PANC-1 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
PBMC	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human PBMC assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human PBMC assessed as cell viability after 24 hrs by MTT assay	[PMID: 24484281]
PC-3	ED₅₀	16.7 1 Compound: 3a, CPT, Camptothecin	Cytotoxicity against human PC3 cells by sulforhodamine B assay Cytotoxicity against human PC3 cells by sulforhodamine B assay	[PMID: 17350834]
PC-3	GI₅₀	0.06 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21115210]
PC-3	GI₅₀	0.09 3 Compound: 1, camptothecin	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 18180162]
PC-3	GI₅₀	0.09 3 Compound: CPT	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 20662543]
PC-3	GI₅₀	0.48 3 Compound: 1	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21388138]
PC-3	GI₅₀	0.7 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay	[PMID: 19715319]
PC-3	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human PC3 cells incubated for 72 hrs by MTT assay Cytotoxicity against human PC3 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
PC-3	IC₅₀	0.01 3 Compound: Camptothecin	Growth inhibition of human PC3 cells after 72 hrs by MTT assay Growth inhibition of human PC3 cells after 72 hrs by MTT assay	[PMID: 24180210]
PC-3	IC₅₀	0.03 3 Compound: Camptothecin	Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
PC-3	IC₅₀	0.1 3 Compound: CPT	Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay	[PMID: 25799376]
PC-3	IC₅₀	0.234 3 Compound: CPT	Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT assay Cytotoxicity against human PC-3 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
PC-3	IC₅₀	0.31 3 Compound: CPT	In vitro cytotoxic activity of compound against human PC3 cell line In vitro cytotoxic activity of compound against human PC3 cell line	[PMID: 15081041]
PC-3	IC₅₀	0.4 3 Compound: Camp	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
PC-3	IC₅₀	1.2 3 Compound: Camptothecin	Antiproliferative activity against human PC3 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as cell viability after 48 hrs by MTT assay	10.1039/C4MD00344F
PC-3	IC₅₀	1.2 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 24041234]
PC-3	IC₅₀	1.4 3 Compound: 1, CPT	Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay Cytotoxicity against p53-deficient human PC3 cells after 48 hrs by SRB assay	[PMID: 19715319]
PC-3	IC₅₀	12 1 Compound: 1a	Cytotoxicity against human PC3 cells after 72 hrs by alamar blue assay Cytotoxicity against human PC3 cells after 72 hrs by alamar blue assay	[PMID: 21341674]
PC-3	IC₅₀	1414.4 1 Compound: Camptothecin (table 1)	Concentration required to inhibit growth of human prostate PC-3 carcinoma cell line Concentration required to inhibit growth of human prostate PC-3 carcinoma cell line	[PMID: 15454230]
PC-3	IC₅₀	16.24 3 Compound: CPT	Cytotoxicity against human PC3 after 48 hrs by SRB assay Cytotoxicity against human PC3 after 48 hrs by SRB assay	[PMID: 21044847]
PC-3	IC₅₀	18.24 3 Compound: Camptothecin	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30109008]
PC-3	IC₅₀	2.4 3 Compound: CPT	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
PC-3	IC₅₀	2.5 3 Compound: CPT	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 26226379]
PC-3	IC₅₀	52 1 Compound: camptothecin	Antiproliferative activity against human PC3 cell line Antiproliferative activity against human PC3 cell line	[PMID: 16686539]
PC-3	IC₅₀	57 1 Compound: CPT	Antiproliferative activity measured against PC-3 human prostate adenocarcinoma Antiproliferative activity measured against PC-3 human prostate adenocarcinoma	[PMID: 9876111]
PC-3	IC₅₀	6.6 3 Compound: CPT	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38154256]
PC-3	IC₅₀	6.96 3 Compound: Camptothecin	Antiproliferative activity against human PC3 cells by MTT assay Antiproliferative activity against human PC3 cells by MTT assay	[PMID: 29131616]
PC-3	IC₅₀	78 1 Compound: CPT	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 24900725]
PC-3	IC₅₀	> 100 3 Compound: CPT	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 37708799]
PC-3	IC₅₀	> 40 3 Compound: Camp	Induction of apoptosis in human PC3 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human PC3 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
PC-3M	IC₅₀	0.19 3 Compound: Camptothecin	Anticancer activity in human PC-3M cells expressing PTB/GFP fusion protein assessed as perinucleolar compartment disassembly and measured after 24 hrs by Hoechst 33342 staining based microscopic method Anticancer activity in human PC-3M cells expressing PTB/GFP fusion protein assessed as perinucleolar compartment disassembly and measured after 24 hrs by Hoechst 33342 staining based microscopic method	[PMID: 35696646]
PC-3M	IC₅₀	0.48 3 Compound: Camptothecin	Cytotoxicity against human PC-3M cells expressing PTB/GFP fusion protein assessed as reduction in ATP level and measured after 24 to 48 hrs by ATPlite luminescence assay Cytotoxicity against human PC-3M cells expressing PTB/GFP fusion protein assessed as reduction in ATP level and measured after 24 to 48 hrs by ATPlite luminescence assay	[PMID: 35696646]
Panel (56 tumour cell lines)	IC₅₀	0.04 3 Compound: 20(S)-Camptothecin	Tested in vitro for cytotoxicity against 56 human tumor cell lines Tested in vitro for cytotoxicity against 56 human tumor cell lines	[PMID: 10714502]
Panel NCI-60 (60 carcinoma cell lines)	GI₅₀	10 1 Compound: Camptothecin E	Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program	[PMID: 15743190]
QG-56	IC₅₀	4.63 14 Compound: 1	In vitro antitumor activity against QG-56 (human lung cancer) cells. In vitro antitumor activity against QG-56 (human lung cancer) cells.	[PMID: 9632364]
QG-56	IC₅₀	4.63 14 Compound: 1a	Tested in vitro for the inhibition of QG-56 (human lung squamous cell carcinoma) cell line by MTT assay Tested in vitro for the inhibition of QG-56 (human lung squamous cell carcinoma) cell line by MTT assay	[PMID: 7932525]
RD	IC₅₀	1.24 3 Compound: CPT	Cytotoxicity against human TE32 cells measured after 72 hrs by MTT assay Cytotoxicity against human TE32 cells measured after 72 hrs by MTT assay	[PMID: 27721148]
RD	IC₅₀	1.24 3 Compound: CPT	Cytotoxicity against human TE32 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human TE32 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28923388]
RD	IC₅₀	1.72 3 Compound: CPT	Cytotoxicity against against human RD cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against against human RD cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30340899]
RD	IC₅₀	4.47 3 Compound: Camptothecin	Cytotoxicity against human TE-32 cells after 72 hrs ny MTT assay Cytotoxicity against human TE-32 cells after 72 hrs ny MTT assay	[PMID: 23974020]
RD	IC₅₀	4.49 3 Compound: Camptothecin	Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 28923382]
RKO	IC₅₀	0.0617 3 Compound: CPT	Antiproliferative activity against human RKO cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human RKO cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
RKO	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human RKO cells measured after 72 hrs by MTT assay Antiproliferative activity against human RKO cells measured after 72 hrs by MTT assay	[PMID: 35462164]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells by MTT method Cytotoxicity against human RPMI8402 cells by MTT method	[PMID: 18771930]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay	[PMID: 19299037]
RPMI 8402	IC₅₀	0.004 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT method Cytotoxicity against human RPMI8402 cells after 4 days by MTT method	[PMID: 19303306]
RPMI 8402	IC₅₀	0.005 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay	[PMID: 18676151]
RPMI 8402	IC₅₀	0.005 3 Compound: Camptothecin	Cytotoxic activity against human lymphoblast tumor cell line RPMI8402 after 4 days of treatment Cytotoxic activity against human lymphoblast tumor cell line RPMI8402 after 4 days of treatment	[PMID: 12747798]
RPMI 8402	IC₅₀	0.006 3 Compound: CPT	Concentration required to inhibit cell proliferation in RPM18402 tumor cell line Concentration required to inhibit cell proliferation in RPM18402 tumor cell line	[PMID: 15482929]
RPMI 8402	IC₅₀	0.006 3 Compound: CPT	Cytotoxicity against human RPMI8402 cells after MTT assay Cytotoxicity against human RPMI8402 cells after MTT assay	[PMID: 18829334]
RPMI 8402	IC₅₀	> 10 3 Compound: CPT	Concentration required to inhibit cell proliferation in CPT-K5 tumor cell line; camptothecin resistant Concentration required to inhibit cell proliferation in CPT-K5 tumor cell line; camptothecin resistant	[PMID: 15482929]
RPMI-7951	IC₅₀	0.22 3 Compound: CPT	Cytotoxicity against human RPMI7951 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human RPMI7951 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32435422]
RPMI-8226	IC₅₀	0.006 3 Compound: CPT	Cytotoxicity against human RPMI8226 cells by MTT method Cytotoxicity against human RPMI8226 cells by MTT method	[PMID: 19012996]
RPMI-8226	IC₅₀	2.05 6 Compound: Camptothecin	Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay	[PMID: 25867737]
Raji	IC₅₀	1 3 Compound: camptothecin	Cytotoxicity against human Raji cells by MTT assay Cytotoxicity against human Raji cells by MTT assay	[PMID: 20329739]
Raji	IC₅₀	3.27 3 Compound: Camptothecin	Cytotoxicity against human Raji cells after 48 hrs by MTT assay Cytotoxicity against human Raji cells after 48 hrs by MTT assay	[PMID: 30109008]
Renca	IC₅₀	304 1 Compound: camptothecin	Antiproliferative activity against mouse Renca cell line Antiproliferative activity against mouse Renca cell line	[PMID: 16686539]
SAOS-2	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human Saos2 cells incubated for 72 hrs by MTT assay Cytotoxicity against human Saos2 cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
SAOS-2	IC₅₀	0.055 3 Compound: CPT	Cytotoxicity against human SAOS-2 cells incubated for 48 hrs by MTT assay Cytotoxicity against human SAOS-2 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
SAS	GI₅₀	6 3 Compound: 1, camptothecin	Antiproliferative activity against human SAS cells after 48 hrs by MTT assay Antiproliferative activity against human SAS cells after 48 hrs by MTT assay	[PMID: 18180162]
SAS	GI₅₀	6 3 Compound: CPT	Cytotoxicity against human SAS cells after 48 hrs by MTT assay Cytotoxicity against human SAS cells after 48 hrs by MTT assay	[PMID: 20662543]
SAS	IC₅₀	6 3 Compound: CPT	Antiproliferative activity against human SAS cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SAS cells incubated for 72 hrs by MTT assay	10.1039/C4MD00133H
SF-268	EC₅₀	0.059 3 Compound: camptothecin	Cytotoxicity against human SF-268 after 3 days by SRB assay Cytotoxicity against human SF-268 after 3 days by SRB assay	[PMID: 15730238]
SF-268	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF268 cell line Antiproliferative activity against human SF268 cell line	[PMID: 16442283]
SF-268	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF268 cells Cytotoxicity against human SF268 cells	[PMID: 17402722]
SF-268	GI₅₀	0.19 3 Compound: CPT	Cytotoxicity against human SF268 cells after 72 hrs by XTT assay Cytotoxicity against human SF268 cells after 72 hrs by XTT assay	[PMID: 20591678]
SF-268	IC₅₀	0.04 3 Compound: Camptothecin	Cytotoxicity against human SF268 cells after 72 hrs by MTS assay Cytotoxicity against human SF268 cells after 72 hrs by MTS assay	[PMID: 21513293]
SF-268	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SF268 cells incubated for 3 days by SRB assay Cytotoxicity against human SF268 cells incubated for 3 days by SRB assay	[PMID: 22863526]
SF-268	IC₅₀	0.19 3 Compound: 4	Anticancer activity against human SF268 cells Anticancer activity against human SF268 cells	[PMID: 21599000]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells Antiproliferative activity against human SF539 cells	[PMID: 18630891]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells Cytotoxicity against human SF539 cells	[PMID: 19783447]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells Cytotoxicity against human SF539 cells	[PMID: 20630766]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells by SRB assay Antiproliferative activity against human SF539 cells by SRB assay	[PMID: 21710981]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells after 48 hrs by SRB assay Cytotoxicity against human SF539 cells after 48 hrs by SRB assay	[PMID: 21823606]
SF-539	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human SF539 cells by SRB assay Cytotoxicity against human SF539 cells by SRB assay	[PMID: 24502276]
SF-539	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human SF539 cells after 48 hrs by SRB assay Growth inhibition of human SF539 cells after 48 hrs by SRB assay	[PMID: 24800942]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells after 48 hrs Antiproliferative activity against human SF539 cells after 48 hrs	[PMID: 27070999]
SF-539	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human SF539 cells assessed as growth inhibition Antiproliferative activity against human SF539 cells assessed as growth inhibition	[PMID: 28657311]
SF-539	GI₅₀	0.01 3 Compound: 1, CPT	Antiproliferative activity against human SF539 cells Antiproliferative activity against human SF539 cells	[PMID: 20155916]
SF-539	GI₅₀	0.01 3 Compound: 1, Camptothecin	Cytotoxicity against human SF539 cells Cytotoxicity against human SF539 cells	[PMID: 17676830]
SF-539	GI₅₀	0.01 3 Compound: 2	Antiproliferative activity against human SF539 cell line Antiproliferative activity against human SF539 cell line	[PMID: 16913702]
SF-539	GI₅₀	0.01 3 Compound: 2	Cytotoxicity against human SF539 cells Cytotoxicity against human SF539 cells	[PMID: 17696418]
SF-539	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
SF-539	GI₅₀	0.01 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human CNS SF-539 cell line Antiproliferative activity was determined for 50% growth inhibition against human CNS SF-539 cell line	[PMID: 11020283]
SF-539	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human SF539 cells after 48 hrs by SRB assay Cytotoxicity against human SF539 cells after 48 hrs by SRB assay	[PMID: 28418653]
SGC-7901	IC₅₀	5.8 3 Compound: CPT	Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay	[PMID: 35868003]
SGC-7901	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
SH-SY5Y	IC₅₀	0.61 3 Compound: CPT	Cytotoxicity against human SH-SY5Y cells expressing low level of topoisomerase I/II measured after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells expressing low level of topoisomerase I/II measured after 72 hrs by MTT assay	[PMID: 35612499]
SH-SY5Y	IC₅₀	> 100 3 Compound: Camptothecin	Growth inhibition of human SH-SY5Y cells after 72 hrs by MTT assay Growth inhibition of human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 27344492]
SK-BR-3	GI₅₀	0.15 3 Compound: Camptothecin	Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay	[PMID: 20438092]
SK-BR-3	IC₅₀	0.21 3 Compound: CPT	Cytotoxicity against HER-positive human SK-BR-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human SK-BR-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
SK-BR-3	IC₅₀	0.38 3 Compound: CPT	Cytotoxicity against HER-positive human SK-BR-3 cells incubated for 48 hrs by CCK-8 assay Cytotoxicity against HER-positive human SK-BR-3 cells incubated for 48 hrs by CCK-8 assay	[PMID: 38104378]
SK-BR-3	IC₅₀	20 1 Compound: CPT	In Vitro cytotoxicity against human breast cancer cell line (SK-BR-3) In Vitro cytotoxicity against human breast cancer cell line (SK-BR-3)	[PMID: 11334569]
SK-BR-3	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human SKBR3 cells after 3 days by SRB assay Cytotoxicity against human SKBR3 cells after 3 days by SRB assay	[PMID: 23142674]
SK-BR-3	IC₅₀	< 0.01 3 Compound: Camptothecin	Antiproliferative activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay	[PMID: 38107170]
SK-HEP1	IC₅₀	0.9 3 Compound: CPT	Antiproliferative activity against human SKHEP1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay Antiproliferative activity against human SKHEP1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay	[PMID: 31880942]
SK-HEP1	IC₅₀	0.96 3 Compound: CPT	Cytotoxicity against human SKHEP1 cells after 72 hrs by MTT assay Cytotoxicity against human SKHEP1 cells after 72 hrs by MTT assay	[PMID: 26226379]
SK-MEL	GI₅₀	0.047 3 Compound: 1	Cytotoxicity against human SK-MEL cells after 72 hrs by MTT assay Cytotoxicity against human SK-MEL cells after 72 hrs by MTT assay	[PMID: 21388138]
SK-MEL-2	IC₅₀	0.075 3 Compound: CPT, campothecin	Cytotoxicity against human SK-MEL-2 cells by SRB assay Cytotoxicity against human SK-MEL-2 cells by SRB assay	[PMID: 17827007]
SK-MEL-2	IC₅₀	0.165 3 Compound: camptothecin	Cytotoxicity against human SK-MEL-2 cells after 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs	[PMID: 17673337]
SK-MEL-2	IC₅₀	6.88 6 Compound: CPT	Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay	[PMID: 21684168]
SK-MEL-2	IC₅₀	7.86 3 Compound: CPT	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by MTT assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by MTT assay	[PMID: 21873069]
SK-MEL-24	IC₅₀	0.46 3 Compound: CPT	Cytotoxicity against human SK-MEL-24 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human SK-MEL-24 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32435422]
SK-MEL-28	CC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay	[PMID: 22047799]
SK-MEL-28	CC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells after 96 hrs by MTT assay	[PMID: 22884523]
SK-MEL-28	IC₅₀	0.04 3 Compound: CPT	Antiproliferative activity against human SK-MEL-28 cells by MTT assay Antiproliferative activity against human SK-MEL-28 cells by MTT assay	[PMID: 17254669]
SK-MEL-28	IC₅₀	2.26 3 Compound: CPT	Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
SK-MEL-28	IC₅₀	< 0.01 3 Compound: Camptothecin	Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay	[PMID: 24180210]
SK-MES-1	CC₅₀	0.03 3 Compound: Camptothecin	Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay	[PMID: 22047799]
SK-MES-1	CC₅₀	0.05 3 Compound: Camptothecin	Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay Cytotoxicity against human SKMES1 cells after 96 hrs by MTT assay	[PMID: 22884523]
SK-MES-1	IC₅₀	0.01 3 Compound: CPT	Antiproliferative activity against human SKMES1 cells by MTT assay Antiproliferative activity against human SKMES1 cells by MTT assay	[PMID: 17254669]
SK-OV-3	IC₅₀	0.014 3 Compound: camptothecin	Cytotoxicity against human SK-OV3 cells after 48 hrs Cytotoxicity against human SK-OV3 cells after 48 hrs	[PMID: 17673337]
SK-OV-3	IC₅₀	0.051 3 Compound: Camptothecin	Inhibitory concentration the viability of SKOV 3 cell population by 50%. Inhibitory concentration the viability of SKOV 3 cell population by 50%.	[PMID: 9003520]
SK-OV-3	IC₅₀	0.241 3 Compound: CPT	Cytotoxicity against human SK-OV-3 cells incubated for 48 hrs by MTT assay Cytotoxicity against human SK-OV-3 cells incubated for 48 hrs by MTT assay	[PMID: 38185054]
SK-OV-3	IC₅₀	1.54 6 Compound: CPT	Cytotoxicity against human SKOV3 cells by sulforhodamine B assay Cytotoxicity against human SKOV3 cells by sulforhodamine B assay	[PMID: 21684168]
SK-OV-3	IC₅₀	2.544 3 Compound: CPT	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 21873069]
SK-OV-3	IC₅₀	2.56 3 Compound: Camptothecin	Antitumor activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
SK-OV-3	IC₅₀	20 1 Compound: CPT	In Vitro cytotoxicity against human ovarian cancer cell line (SK-OV-3) In Vitro cytotoxicity against human ovarian cancer cell line (SK-OV-3)	[PMID: 11334569]
SK-OV-3	IC₅₀	3.82 3 Compound: CPT	Cytotoxicity against HER-positive human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against HER-positive human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 36351049]
SK-OV-3	IC₅₀	37 1 Compound: 1	Cytotoxicity was determined in vitro in SK-OV-3 cells (ovarian) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in SK-OV-3 cells (ovarian) of human tumor cell lines by using MTT assay	[PMID: 7853331]
SK-OV-3	IC₅₀	4.07 3 Compound: CPT	Cytotoxicity against HER-positive human SK-OV-3 cells incubated for 48 hrs by CCK-8 assay Cytotoxicity against HER-positive human SK-OV-3 cells incubated for 48 hrs by CCK-8 assay	[PMID: 38104378]
SK-OV-3	IC₅₀	4.86 3 Compound: Camptothecin	Antitumor activity against taxol-resistant human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against taxol-resistant human SK-OV-3 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
SK-OV-3	IC₅₀	5.5 1 Compound: CPT	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 analysis	[PMID: 34952177]
SK-OV-3	IC₅₀	5.5 x 10^-3 3 Compound: CPT	Antiproliferative activity against human SKOV3 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human SKOV3 cells after 48 hrs by CCK-8 assay	[PMID: 29501943]
SK-OV-3	IC₅₀	5.5 x 10^-3 3 Compound: CPT	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by CCK-8 assay	[PMID: 33962152]
SK-OV-3	IC₅₀	5.5 x 10^-3 3 Compound: Camptothecin	Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by CCK8 assay Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by CCK8 assay	[PMID: 27017547]
SK-OV-3	IC₅₀	5.5 x 10^-3 3 Compound: I; CPT	Antiproliferative activity against human SKOV3 cells incubated for 48 hrs by CCK8 assay Antiproliferative activity against human SKOV3 cells incubated for 48 hrs by CCK8 assay	[PMID: 31229877]
SK-OV-3	IC₅₀	5.5 3 Compound: I; CPT	Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK8 assay	[PMID: 32279049]
SK-VLB	IC₅₀	0.053 3 Compound: Camptothecin	Inhibitory concentration that reduced the viability of SKVLB cell population by 50%. Inhibitory concentration that reduced the viability of SKVLB cell population by 50%.	[PMID: 9003520]
SK-VLB	IC₅₀	41 1 Compound: 1	Cytotoxicity was determined in vitro in SKVLB cells(ovarian with upregulated MDRp-glycoprotein) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in SKVLB cells(ovarian with upregulated MDRp-glycoprotein) of human tumor cell lines by using MTT assay	[PMID: 7853331]
SMMC-7721	IC₅₀	0.003 3 Compound: camptothecin	Cytotoxicity against human SMMC7721 cells after 48 hrs by SRB assay Cytotoxicity against human SMMC7721 cells after 48 hrs by SRB assay	[PMID: 21973054]
SMMC-7721	IC₅₀	0.02 3 Compound: CPT	Cytotoxicity against human SMMC7721 after 48 hrs by SRB assay Cytotoxicity against human SMMC7721 after 48 hrs by SRB assay	[PMID: 21044847]
SMMC-7721	IC₅₀	0.45 3 Compound: CPT; 1	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 30509782]
SMMC-7721	IC₅₀	1.08 3 Compound: CPT	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 30125725]
SMMC-7721	IC₅₀	3.95 3 Compound: Camptothecin	Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell growth by SRB assay Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell growth by SRB assay	[PMID: 38107170]
SMMC-7721	IC₅₀	> 10 3 Compound: CPT	Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34852457]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cell line Antiproliferative activity against human SN12C cell line	[PMID: 16442283]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells Cytotoxicity against human SN12C cells	[PMID: 17402722]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells Antiproliferative activity against human SN12C cells	[PMID: 18630891]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells Cytotoxicity against human SN12C cells	[PMID: 19783447]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells Cytotoxicity against human SN12C cells	[PMID: 20630766]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells by SRB assay Antiproliferative activity against human SN12C cells by SRB assay	[PMID: 21710981]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells after 48 hrs by SRB assay Cytotoxicity against human SN12C cells after 48 hrs by SRB assay	[PMID: 21823606]
SN12C	GI₅₀	0.02 3 Compound: 1	Cytotoxicity against human SN12C cells by SRB assay Cytotoxicity against human SN12C cells by SRB assay	[PMID: 24502276]
SN12C	GI₅₀	0.02 3 Compound: 1	Growth inhibition of human SN12C cells after 48 hrs by SRB assay Growth inhibition of human SN12C cells after 48 hrs by SRB assay	[PMID: 24800942]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells after 48 hrs Antiproliferative activity against human SN12C cells after 48 hrs	[PMID: 27070999]
SN12C	GI₅₀	0.02 3 Compound: 1	Antiproliferative activity against human SN12C cells assessed as growth inhibition Antiproliferative activity against human SN12C cells assessed as growth inhibition	[PMID: 28657311]
SN12C	GI₅₀	0.02 3 Compound: 1, CPT	Antiproliferative activity against human SN12C cells Antiproliferative activity against human SN12C cells	[PMID: 20155916]
SN12C	GI₅₀	0.02 3 Compound: 1, Camptothecin	Cytotoxicity against human SN12C cells Cytotoxicity against human SN12C cells	[PMID: 17676830]
SN12C	GI₅₀	0.02 3 Compound: 18	Cytotoxicity against human SN12C cells after 48 hrs by SRB assay Cytotoxicity against human SN12C cells after 48 hrs by SRB assay	[PMID: 28418653]
SN12C	GI₅₀	0.02 3 Compound: 2	Growth inhibitory activity against human renal SN12C cell line Growth inhibitory activity against human renal SN12C cell line	[PMID: 15509164]
SN12C	GI₅₀	0.02 3 Compound: 2	Antiproliferative activity against human SN12C cell line Antiproliferative activity against human SN12C cell line	[PMID: 16913702]
SN12C	GI₅₀	0.02 3 Compound: 2	Cytotoxicity against human SN12C cells Cytotoxicity against human SN12C cells	[PMID: 17696418]
SN12C	GI₅₀	0.02 3 Compound: 2	Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
SN12C	GI₅₀	0.02 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human renal SN12C cell line Antiproliferative activity was determined for 50% growth inhibition against human renal SN12C cell line	[PMID: 11020283]
SN12C	GI₅₀	0.02 3 Compound: Camptothecin	Concentration required to inhibit the growth of human Renal SN12C cells Concentration required to inhibit the growth of human Renal SN12C cells	[PMID: 16033260]
SNU-475	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human SNU475 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay Cytotoxicity against human SNU475 cells assessed as growth inhibition after 72 hrs by sulforhodamine B assay	[PMID: 26810835]
SNU-638	IC₅₀	0.098 3 Compound: 1, CPT	Cytotoxicity against human SNU638 cells Cytotoxicity against human SNU638 cells	[PMID: 21095131]
SNU-638	IC₅₀	0.098 3 Compound: CPT	Cytotoxicity against human SNU638 cells by MTT assay Cytotoxicity against human SNU638 cells by MTT assay	[PMID: 21353568]
SNU-638	IC₅₀	0.098 3 Compound: camptothecin	Cytotoxicity against human SNU638 cells by SRB assay Cytotoxicity against human SNU638 cells by SRB assay	[PMID: 17498951]
SNU-638	IC₅₀	0.28 3 Compound: Camptothecin	Cytotoxicity against human SNU638 cells by MTT assay Cytotoxicity against human SNU638 cells by MTT assay	[PMID: 23608763]
SU-DHL-2	IC₅₀	0.94 3 Compound: Camptothecin	Antitumor activity against human SUDHL2 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human SUDHL2 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
SW-620	EC₅₀	0.0021 3 Compound: Cpt, camptothecin	Antiproliferative activity against human SW620 cells by soft agar assay Antiproliferative activity against human SW620 cells by soft agar assay	[PMID: 17287122]
SW-620	EC₅₀	0.15 1 Compound: Camptothecin	Concentration required to inhibit growth of SW620 (human colon cancer) cells in the presence of 10 uM of Compound 2e Concentration required to inhibit growth of SW620 (human colon cancer) cells in the presence of 10 uM of Compound 2e	[PMID: 15857116]
SW-620	EC₅₀	1.2 1 Compound: Camptothecin	Concentration required to inhibit growth of SW620 (human colon cancer) cells Concentration required to inhibit growth of SW620 (human colon cancer) cells	[PMID: 15857116]
SW1573	GI₅₀	0.21 3 Compound: CPT	Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
SW1573	GI₅₀	0.25 3 Compound: Camptothecin	Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay	[PMID: 23831507]
SW1573	GI₅₀	0.3 3 Compound: Camptothecin	Antiproliferative activity against human SW1573 cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay	[PMID: 37531922]
SW1990	IC₅₀	0.2 3 Compound: CPT	Antitumor activity against human SW1990 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay Antitumor activity against human SW1990 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay	[PMID: 32668379]
SW480	IC₅₀	0.01 6 Compound: 1	Cytotoxicity in SW480 cancer cell line Cytotoxicity in SW480 cancer cell line	10.1016/S0960-894X(01)80158-X
SW480	IC₅₀	0.21 3 Compound: Camptothecin	Antiproliferation activity against human SW480 cells assessed as reduction in cell viability measured after 72 hours by MTT assay Antiproliferation activity against human SW480 cells assessed as reduction in cell viability measured after 72 hours by MTT assay	[PMID: 32201190]
SW480	IC₅₀	0.29 3 Compound: CPT; 1	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 30509782]
SW480	IC₅₀	3.75 3 Compound: Camptothecin	Inhibition of DNA topoisomerase 1 in Homo sapiens (human) SW480 cells Inhibition of DNA topoisomerase 1 in Homo sapiens (human) SW480 cells	10.1007/s00044-009-9233-5
SW480	IC₅₀	8.56 3 Compound: CPT	Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38128233]
SW626	IC₅₀	28.7 1 Compound: Camptothecin	Cytotoxicity against human SW626 cells by MTT assay Cytotoxicity against human SW626 cells by MTT assay	[PMID: 11858760]
SW948	IC₅₀	0.16 3 Compound: CPT	Antiproliferative activity against human SW948 cells after 3 days by XTT assay Antiproliferative activity against human SW948 cells after 3 days by XTT assay	[PMID: 19691293]
Sf9	IC₅₀	0.025 3 Compound: CPT	Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis	[PMID: 30897325]
SiHa	GI₅₀	0.55 3 Compound: Camptothecin	Antiproliferative activity against human SiHa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human SiHa cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
Splenocyte	CC₅₀	0.62 3 Compound: CPT	Cytotoxicity against BALB/c mouse splenocytes assessed as cell viability after 48 hrs by alamar blue assay Cytotoxicity against BALB/c mouse splenocytes assessed as cell viability after 48 hrs by alamar blue assay	[PMID: 27639365]
T-24	IC₅₀	0.006 3 Compound: camptothecin	Growth inhibition of human T24 cells by neutral red assay Growth inhibition of human T24 cells by neutral red assay	[PMID: 17204425]
T-24	IC₅₀	3.09 3 Compound: CPT	Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30875505]
T-24	IC₅₀	6.8 3 Compound: CPT	Antiproliferative activity against human T24 cells after 48 hrs by MTT assay Antiproliferative activity against human T24 cells after 48 hrs by MTT assay	[PMID: 30685528]
T-24	IC₅₀	88 1 Compound: 1, CPT, NSC-100880	Cytotoxicity against human chemo-resistant T24 cells by WST assay Cytotoxicity against human chemo-resistant T24 cells by WST assay	[PMID: 23578545]
T-24	IC₅₀	88 1 Compound: CPT	Cytotoxicity against T24 tumor cell line determined by WST-1 assay Cytotoxicity against T24 tumor cell line determined by WST-1 assay	[PMID: 10841808]
T47D	GI₅₀	1.9 3 Compound: CPT	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
T47D	GI₅₀	2 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
T47D	GI₅₀	2 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 48 hrs by SRB assay Antiproliferative activity against human T47D cells after 48 hrs by SRB assay	[PMID: 23831507]
T47D	GI₅₀	2 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay Antiproliferative activity against human T47D cells assessed as inhibition of culture growth incubated for 48 hrs by SRB assay	[PMID: 37531922]
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Cytotoxicity against human T47D cells by MTT assay Cytotoxicity against human T47D cells by MTT assay	[PMID: 23608763]
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay	[PMID: 29402741]
T47D	IC₅₀	0.07 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay	[PMID: 30262132]
T47D	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by CCK8 assay Cytotoxicity against human T47D cells after 2 days by CCK8 assay	[PMID: 26361737]
T47D	IC₅₀	0.08 3 Compound: Camptothecin	Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay	[PMID: 27484510]
T47D	IC₅₀	0.09 3 Compound: CPT	Antiproliferative activity against human T47D cells after 72 hrs by EZ-Cytox colorimetric assay Antiproliferative activity against human T47D cells after 72 hrs by EZ-Cytox colorimetric assay	[PMID: 34678573]
T47D	IC₅₀	0.25 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells measured after 72 hrs by EZ-Cytox assay Antiproliferative activity against human T47D cells measured after 72 hrs by EZ-Cytox assay	[PMID: 31398033]
T47D	IC₅₀	0.28 3 Compound: CPT	Cytotoxicity against human T47D cells after 2 days Cytotoxicity against human T47D cells after 2 days	[PMID: 24904965]
T47D	IC₅₀	0.3 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by CCK-8 assay Cytotoxicity against human T47D cells after 2 days by CCK-8 assay	[PMID: 24013413]
T47D	IC₅₀	0.31 3 Compound: Camptothecin	Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay	[PMID: 26022080]
T47D	IC₅₀	0.49 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay	[PMID: 29510948]
T47D	IC₅₀	0.59 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay	[PMID: 27654394]
T47D	IC₅₀	0.75 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 4 days by CCK-8 assay Cytotoxicity against human T47D cells after 4 days by CCK-8 assay	[PMID: 25062006]
T47D	IC₅₀	1.53 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis	[PMID: 22503656]
T47D	IC₅₀	1.62 3 Compound: CPT	Cytotoxicity against human T47D cells measured after 2 days by MTT assay Cytotoxicity against human T47D cells measured after 2 days by MTT assay	[PMID: 26334499]
T47D	IC₅₀	1.84 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay	[PMID: 26945111]
T47D	IC₅₀	1.84 3 Compound: camptothecin	Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay	[PMID: 25936262]
T47D	IC₅₀	11.17 3 Compound: Camptothecin	Cytotoxicity against human T47D cells after 3 days by CCK8 assay Cytotoxicity against human T47D cells after 3 days by CCK8 assay	[PMID: 26927425]
T47D	IC₅₀	13.7 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 27643560]
T47D	IC₅₀	2.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28068603]
T47D	IC₅₀	2.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28384547]
T47D	IC₅₀	2.31 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 28633898]
T47D	IC₅₀	207 1 Compound: 1	Cytotoxicity was determined in vitro in T47D cells(breast) of human tumor cell lines by using MTT assay Cytotoxicity was determined in vitro in T47D cells(breast) of human tumor cell lines by using MTT assay	[PMID: 7853331]
T47D	IC₅₀	3.67 3 Compound: Camptothecin	Cytotoxicity against human T47D cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay Cytotoxicity against human T47D cells assessed as cell growth inhibition measured after 2 days by cell counting kit-8 assay	[PMID: 27707625]
T47D	IC₅₀	4.1 3 Compound: Camptothecin	Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay	[PMID: 26988802]
T47D	IC₅₀	9.17 3 Compound: CPT	Cytotoxicity against human T47D cells after 72 hrs by MTT assay Cytotoxicity against human T47D cells after 72 hrs by MTT assay	[PMID: 22819942]
T47D	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human T47D cells after 3 days by SRB assay Cytotoxicity against human T47D cells after 3 days by SRB assay	[PMID: 23142674]
T47D	IC₅₀	< 1 3 Compound: CPT	Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
TERT-RPE1	ED₅₀	230 1 Compound: camptothecin	Cytotoxicity against human telomerase reverse transcriptase expressing human RPE1 cells Cytotoxicity against human telomerase reverse transcriptase expressing human RPE1 cells	[PMID: 15043407]
TERT-RPE1	IC₅₀	27.2 3 Compound: Camp	Induction of apoptosis in human RPE1 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay Induction of apoptosis in human RPE1 cells assessed as caspase 3/7 activity after 24 hrs by caspase-glo luminescent assay	[PMID: 29223099]
TERT-RPE1	IC₅₀	> 40 3 Compound: Camp	Cytotoxicity against human RPE1 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay Cytotoxicity against human RPE1 cells assessed as reduction in cell viability after 48 hrs by ATPlite-based luminescent assay	[PMID: 29223099]
THP-1	EC₅₀	0.16 3 Compound: camptothecin	Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method Cytotoxicity against human THP1 cells after 72 hrs by erythosin B staining method	[PMID: 20192247]
THP-1	IC₅₀	0.071 3 Compound: Camptothecin	Cytotoxicity against human THP1 cells after 2 days by MTT assay Cytotoxicity against human THP1 cells after 2 days by MTT assay	[PMID: 22325897]
THP-1	IC₅₀	0.6 3 Compound: 1, CPT	Cytotoxicity against human THP1 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human THP1 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
THP-1	IC₅₀	1.89 3 Compound: Camptothecin	Antitumor activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
Tumor Cell line	GI₅₀	44 1 Compound: camptothecin	Mean GI50 against variety of human tumor cell lines Mean GI50 against variety of human tumor cell lines	[PMID: 11052802]
U-251	GI₅₀	0.01 3 Compound: Camptothecin	Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 48 hrs by sulphorhodamine B assay	[PMID: 29313676]
U-373MG ATCC	GI₅₀	0.033 3 Compound: 1	Cytotoxicity against human U373 cells after 72 hrs by MTT assay Cytotoxicity against human U373 cells after 72 hrs by MTT assay	[PMID: 21388138]
U-373MG ATCC	IC₅₀	0.015 3 Compound: Camptothecin	Growth inhibition of human U373 cells after 72 hrs by MTT assay Growth inhibition of human U373 cells after 72 hrs by MTT assay	[PMID: 24180210]
U-87MG ATCC	IC₅₀	0.25 3 Compound: 21	Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability	[PMID: 32858470]
U-87MG ATCC	IC₅₀	0.5 3 Compound: Camptothecin	Cytotoxicity against human U87 cells after 72 hrs by MTT assay Cytotoxicity against human U87 cells after 72 hrs by MTT assay	[PMID: 21186067]
U-87MG ATCC	IC₅₀	< 1.85 3 Compound: CPT	Antiproliferative activity against human U87 cells measured after 72 hrs by MTT assay Antiproliferative activity against human U87 cells measured after 72 hrs by MTT assay	[PMID: 35462164]
U-937	IC₅₀	0.015 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay	[PMID: 17158054]
U-937	IC₅₀	0.032 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay	[PMID: 17158054]
U-937	IC₅₀	0.3 3 Compound: 1, CPT	Cytotoxicity against human U937 cells expressing p53 mutant after 48 hrs by SRB assay Cytotoxicity against human U937 cells expressing p53 mutant after 48 hrs by SRB assay	[PMID: 19715319]
U-937	IC₅₀	0.68 3 Compound: camptothecin	Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay	[PMID: 17158054]
U-937	IC₅₀	1.81 3 Compound: Camptothecin	Antitumor activity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs Antitumor activity against human U-937 cells assessed as reduction in cell viability incubated for 72 hrs	[PMID: 36906964]
U-937	IC₅₀	1.98 3 Compound: Camptothecin	Cytotoxicity against human U937 cells after 2 days by MTT assay Cytotoxicity against human U937 cells after 2 days by MTT assay	[PMID: 22325897]
U-937	IC₅₀	18.24 3 Compound: Camptothecin	Antiproliferative activity against human U-937 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay Antiproliferative activity against human U-937 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 36996717]
U2OS	GI₅₀	> 287 3 Compound: 1, CPT	Cytotoxicity against human U2OS cells incubated for 72 hrs by MTT assay Cytotoxicity against human U2OS cells incubated for 72 hrs by MTT assay	[PMID: 22867019]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cell line Antiproliferative activity against human UACC62 cell line	[PMID: 16442283]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells Cytotoxicity against human UACC62 cells	[PMID: 17402722]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells Antiproliferative activity against human UACC62 cells	[PMID: 18630891]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells Cytotoxicity against human UACC62 cells	[PMID: 19783447]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells Cytotoxicity against human UACC62 cells	[PMID: 20630766]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells by SRB assay Antiproliferative activity against human UACC62 cells by SRB assay	[PMID: 21710981]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay	[PMID: 21823606]
UACC-62	GI₅₀	0.01 3 Compound: 1	Cytotoxicity against human UACC62 cells by SRB assay Cytotoxicity against human UACC62 cells by SRB assay	[PMID: 24502276]
UACC-62	GI₅₀	0.01 3 Compound: 1	Growth inhibition of human UACC62 cells after 48 hrs by SRB assay Growth inhibition of human UACC62 cells after 48 hrs by SRB assay	[PMID: 24800942]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells after 48 hrs Antiproliferative activity against human UACC62 cells after 48 hrs	[PMID: 27070999]
UACC-62	GI₅₀	0.01 3 Compound: 1	Antiproliferative activity against human UACC62 cells assessed as growth inhibition Antiproliferative activity against human UACC62 cells assessed as growth inhibition	[PMID: 28657311]
UACC-62	GI₅₀	0.01 3 Compound: 1, CPT	Antiproliferative activity against human UACC62 cells Antiproliferative activity against human UACC62 cells	[PMID: 20155916]
UACC-62	GI₅₀	0.01 3 Compound: 1, Camptothecin	Cytotoxicity against human UACC62 cells Cytotoxicity against human UACC62 cells	[PMID: 17676830]
UACC-62	GI₅₀	0.01 3 Compound: 2	Growth inhibitory activity against human melanoma UACC-62 cell line Growth inhibitory activity against human melanoma UACC-62 cell line	[PMID: 15509164]
UACC-62	GI₅₀	0.01 3 Compound: 2	Antiproliferative activity against human UACC62 cell line Antiproliferative activity against human UACC62 cell line	[PMID: 16913702]
UACC-62	GI₅₀	0.01 3 Compound: 2	Cytotoxicity against human UACC62 cells Cytotoxicity against human UACC62 cells	[PMID: 17696418]
UACC-62	GI₅₀	0.01 3 Compound: 2	Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay	[PMID: 22329436]
UACC-62	GI₅₀	0.01 3 Compound: 2 (Camptothecin)	Antiproliferative activity was determined for 50% growth inhibition against human melanoma UACC-62 cell line Antiproliferative activity was determined for 50% growth inhibition against human melanoma UACC-62 cell line	[PMID: 11020283]
UACC-62	GI₅₀	0.01 3 Compound: Camptothecin	Concentration required to inhibit the growth of human Melanoma UACC-62 cells Concentration required to inhibit the growth of human Melanoma UACC-62 cells	[PMID: 16033260]
UACC-62	GI₅₀	< 0.01 3 Compound: 18	Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay	[PMID: 28418653]
Vero	IC₅₀	0.02 6 Compound: camptothecin	Cytotoxicity against african green monkey Vero cells after 7 days by XTT assay Cytotoxicity against african green monkey Vero cells after 7 days by XTT assay	[PMID: 8021652]
Vero	IC₅₀	0.054 6 Compound: camptothecin	Cytotoxicity against african green monkey Vero cells Cytotoxicity against african green monkey Vero cells	[PMID: 8254347]
Vero	IC₅₀	0.054 6 Compound: camptothecin	Cytotoxicity against african green monkey Vero cells Cytotoxicity against african green monkey Vero cells	[PMID: 9514005]
Vero	IC₅₀	0.6 6 Compound: Camptothecin	Cytotoxicity against african green monkey Vero cells Cytotoxicity against african green monkey Vero cells	[PMID: 21985060]
Vero	IC₅₀	27 3 Compound: Camptothecin	Inhibition topoisomerase 1 in african green monkey Vero cells assessed as conversion of supercoiled pBR322 DNA to relaxed form Inhibition topoisomerase 1 in african green monkey Vero cells assessed as conversion of supercoiled pBR322 DNA to relaxed form	[PMID: 11430001]
Vero	IC₅₀	58 6 Compound: Camptothecin	Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells by MTT assay Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells by MTT assay	10.1007/s00044-010-9381-7
WI-38	IC₅₀	0.03 3 Compound: Camptothecin	Cytotoxicity against human WI38 cells after 48 hrs by WST-1 assay Cytotoxicity against human WI38 cells after 48 hrs by WST-1 assay	[PMID: 28557449]
WI-38	IC₅₀	0.03 6 Compound: camptothecin	Cytotoxicity against human WI38 cells assessed as cell viability by WST-1 assay Cytotoxicity against human WI38 cells assessed as cell viability by WST-1 assay	[PMID: 24593048]
WI-38	IC₅₀	0.23 3 Compound: Campthotecin	Cytotoxicity against human WI38 cells by MTT assay Cytotoxicity against human WI38 cells by MTT assay	[PMID: 26063305]
WI-38	IC₅₀	0.4 6 Compound: Camptothecin	Cytotoxicity against human WI38 cells by MTT assay Cytotoxicity against human WI38 cells by MTT assay	[PMID: 23816880]
WI-38	IC₅₀	786 1 Compound: CPT	Cytotoxicity against human WI38 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human WI38 cells overexpressing biotin receptor assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24901491]
WI-38	IC₅₀	8.37 3 Compound: CPT	Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay	[PMID: 30685528]
WIL2-NS	CC₅₀	0.005 3 Compound: Camptothecin	Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay	[PMID: 22047799]
WIL2-NS	CC₅₀	0.005 3 Compound: Camptothecin	Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay Cytotoxicity against human WIL2-NS cells after 96 hrs by MTT assay	[PMID: 22884523]
WIL2-NS	IC₅₀	0.005 3 Compound: CPT	Antiproliferative activity against human WIL-2NS cells by MTT assay Antiproliferative activity against human WIL-2NS cells by MTT assay	[PMID: 17254669]
WiDr	ED₅₀	0.07 6 Compound: Camptothecin	Cytotoxicity against human WiDr cells by MTT assay Cytotoxicity against human WiDr cells by MTT assay	[PMID: 18220355]
WiDr	GI₅₀	1.7 3 Compound: CPT	Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
WiDr	GI₅₀	1.8 3 Compound: Camptothecin	Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay	[PMID: 23831507]
WiDr	IC₅₀	0.07 6 Compound: camptothecin	Cytotoxicity against human WiDr cells by MTT assay Cytotoxicity against human WiDr cells by MTT assay	[PMID: 18774864]
WiDr	IC₅₀	17 1 Compound: CPT	In Vitro cytotoxicity against human colon cancer cell line (WiDr) In Vitro cytotoxicity against human colon cancer cell line (WiDr)	[PMID: 11334569]
ZR-75-1	IC₅₀	< 0.01 3 Compound: CPT	Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay	[PMID: 23142674]
ZR-75-30	IC₅₀	0.24 3 Compound: CPT	Antiproliferative activity against human ZR-7530 cells after 72 hrs by MTT assay Antiproliferative activity against human ZR-7530 cells after 72 hrs by MTT assay	[PMID: 28351590]
carcinoma cell line	IC₅₀	0.33 3 Compound: CPT (Camptothecin)	Cytotoxicity against human non-small-cell lung carcinoma cell line H460 (NSCLC-H460) Cytotoxicity against human non-small-cell lung carcinoma cell line H460 (NSCLC-H460)	[PMID: 11563925]

In Vitro

High TOP1 enzymatic activity MCF7 (Luminal subtype) and HCC1419 (HER2 subtype) show high sensitivity toward Camptothecin (0.1 μM to 5 μM; 72 hours) treatment, exhibiting the IC₅₀ values of 0.089 μM and 0.067 μM, respectively^[4].
Camptothecin (0.5 μM; 6 and 24 hours) reduces desferrioxamine-activated VEGF expression.
Camptothecin (0.5 μM; 8 to 24 hours) strongly prevents the desferrioxamine-dependent HIF-1a accumulation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[4]

Cell Line:	MCF7 (Luminal subtype) and HCC1419 (HER2 subtype)
Concentration:	0.1 μM to 5 μM
Incubation Time:	72 hours
Result:	High TOP1 enzymatic activity MCF7 (Luminal subtype) and HCC1419 (HER2 subtype) show high sensitivity toward CPT (0.1 μM to 5 μM; 72 hours) treatment, exhibiting the IC₅₀ values of 0.089 μM and 0.067 μM, respectively.

RT-PCR^[2]

Cell Line:	HeLa and HEK293 cell lines
Concentration:	0.5 μmol/L
Incubation Time:	6 and 24 hours
Result:	Reduces desferrioxamine-activated VEGF expression in both cell lines after 6 and 24 hours of treatment, whereas in normoxic condition camptothecin does not affect the VEGF mRNA level.

Western Blot Analysis^[2]

Cell Line:	HeLa and HEK293 cell lines
Concentration:	0.5 μmol/L
Incubation Time:	8 to 24 hours
Result:	Strongly prevents the desferrioxamine-dependent HIF-1a accumulation after 8 to 24 hours, whereas it does not affect HIF-1b levels.

In Vivo

Camptothecin (2 mg/kg every other day) treats mice, has developed numerous pulmonary metastases.
Treatment with both kinase inhibitor of nuclear factor-kappaB-1 (KINK-1) and Camptothecin led to a statistically significant reduction in the number of pulmonary metastases^[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	C57BL6 mice (injected with B16F10 melanoma cells)^[5]
Dosage:	2 mg/kg
Administration:	every other day, after 19 days
Result:	Has developed numerous pulmonary metastases.

Clinical Trial

분자량

348.35

화학식

C₂₀H₁₆N₂O₄

CAS No.

7689-03-4

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C([C@@](O)(CC)C(OC2)=O)C=C(N1C3)C(C3=C4)=NC5=C4C=CC=C5

Structure Classification

Initial Source

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)

용액&용해도

In Vitro:

1M NaOH : 10 mg/mL (28.71 mM; ultrasonic and adjust pH to 11 with NaOH)

DMSO : 6.25 mg/mL (17.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8707 mL	14.3534 mL	28.7068 mL
5 mM	0.5741 mL	2.8707 mL	5.7414 mL
10 mM	0.2871 mL	1.4353 mL	2.8707 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (protect from light). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 15% Cremophor EL 85% Saline
Solubility: 10 mg/mL (28.71 mM); Suspended solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.77%

Select Batch:

Data Sheet (287 KB) SDS (644 KB)

COA (259 KB) RP-HPLC (243 KB)

Handling Instructions (2659 KB)

References

[1]. Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. [Content Brief]

[2]. Bertozzi D, et al. The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells. Mol Cancer Ther. 2014;13(1):239-248. [Content Brief]

[3]. Huang Q, et al. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents. Eur J Med Chem. 2013;63:746-757. [Content Brief]

[4]. Tesauro C, et al. Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study. BMC Cancer. 2019;19(1):1158. Published 2019 Nov 29. [Content Brief]

[5]. Schön M, et al. KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment. J Natl Cancer Inst. 2008;100(12):862-875.. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / 1M NaOH	1 mM	2.8707 mL	14.3534 mL	28.7068 mL	71.7669 mL
	5 mM	0.5741 mL	2.8707 mL	5.7414 mL	14.3534 mL
	10 mM	0.2871 mL	1.4353 mL	2.8707 mL	7.1767 mL
	15 mM	0.1914 mL	0.9569 mL	1.9138 mL	4.7845 mL
1M NaOH	20 mM	0.1435 mL	0.7177 mL	1.4353 mL	3.5883 mL
1M NaOH	25 mM	0.1148 mL	0.5741 mL	1.1483 mL	2.8707 mL

Camptothecin Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Camptothecin (Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT)

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Other Forms of Camptothecin:

68 Publications Citing Use of MCE Camptothecin

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Camptothecin Related Classifications

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Camptothecin (Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT)

고객리뷰

Other Forms of Camptothecin:

Camptothecin Related Antibodies

68 Publications Citing Use of MCE Camptothecin

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Topoisomerase Isoform Specific Products:

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References

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Camptothecin Related Antibodies

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농도 희석 계산기

Complete Stock Solution Preparation Table

Camptothecin Related Classifications

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